Searching for up to 100 curated homologs for WP_015944362.1 NCBI__GCF_000021925.1:WP_015944362.1 (327 a.a.)
Found high-coverage hits (≥70%) to 71 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
J9H7D1 asparaginase (EC 3.5.1.1) from Staphylococcus sp. (see paper)
37% identity, 98% coverage of query (219 bits)
7c8xA Blasnase-t13a with l-asn
36% identity, 94% coverage of query (193 bits)
7c8qA Blasnase-t13a with d-asn
35% identity, 94% coverage of query (192 bits)
8h4aB / A0A6I7U6Y2 Blasnase-t13a/m57p
35% identity, 94% coverage of query (191 bits)
7cbuA Blasnase-t13a with l-asp
35% identity, 94% coverage of query (189 bits)
2wltA / Q9ZLB9 The crystal structure of helicobacter pylori l-asparaginase at 1.4 a resolution (see paper)
31% identity, 97% coverage of query (175 bits)
2gvnA / I1SBD9 L-asparaginase from erwinia carotovora in complex with aspartic acid (see paper)
35% identity, 94% coverage of query (170 bits)
A0A2X5A091 asparaginase (EC 3.5.1.1); glutaminase (EC 3.5.1.2) from Helicobacter pylori (see paper)
30% identity, 97% coverage of query (169 bits)
P50286 asparaginase (EC 3.5.1.1) from Wolinella succinogenes (see paper)
33% identity, 98% coverage of query (169 bits)
ansB1 / Q6Q4F4 L-asparaginase subunit (EC 3.5.1.38) from Pectobacterium atrosepticum (see 10 papers)
Q6Q4F4 asparaginase (EC 3.5.1.1) from Pectobacterium atrosepticum (see paper)
34% identity, 98% coverage of query (169 bits)
ASPG2_BACSU / O34482 L-asparaginase 2; L-ASNase 2; L-asparagine amidohydrolase 2; EC 3.5.1.1 from Bacillus subtilis (strain 168) (see paper)
34% identity, 94% coverage of query (169 bits)
Q9ZLB9 asparaginase (EC 3.5.1.1) from Helicobacter pylori J99 (see paper)
31% identity, 97% coverage of query (169 bits)
5k3oA / P50286 Wolinella succinogenes l-asparaginase p121 and l-aspartic acid (see paper)
33% identity, 98% coverage of query (168 bits)
5k45A Wolinella succinogenes l-asparaginase p121 + l-glutamic acid
33% identity, 98% coverage of query (168 bits)
B6ZCD8 asparaginase (EC 3.5.1.1) from Helicobacter pylori (see paper)
I0ZIE0 asparaginase (EC 3.5.1.1) from Helicobacter pylori (see paper)
30% identity, 97% coverage of query (167 bits)
BPHYT_RS08815 L-asparaginase (EC 3.5.1.1) from Burkholderia phytofirmans PsJN
35% identity, 92% coverage of query (166 bits)
2hlnA L-asparaginase from erwinia carotovora in complex with glutamic acid
33% identity, 98% coverage of query (166 bits)
1jazA Crystal structure of monoclinic form of d90e mutant of escherichia coli asparaginase ii
32% identity, 99% coverage of query (162 bits)
7r5qA Escherichia coli type ii asparaginase n24s mutant in complex with glu
32% identity, 99% coverage of query (162 bits)
AnsB / b2957 L-asparaginase 2 (EC 3.5.1.38; EC 3.5.1.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ansB / P00805 L-asparaginase 2 (EC 3.5.1.38) from Escherichia coli (strain K12) (see 73 papers)
ASPG2_ECOLI / P00805 L-asparaginase 2; L-asparaginase II; L-ASNase II; L-asparagine amidohydrolase II; Colaspase; EC 3.5.1.1 from Escherichia coli (strain K12) (see 5 papers)
33% identity, 92% coverage of query (160 bits)
C0KWF5 asparaginase (EC 3.5.1.1) from Escherichia coli (see paper)
32% identity, 90% coverage of query (160 bits)
Q6Q4F3 asparaginase (EC 3.5.1.1) from Dickeya chrysanthemi (see 2 papers)
33% identity, 94% coverage of query (160 bits)
1ho3A Crystal structure analysis of e. Coli l-asparaginase ii (y25f mutant)
33% identity, 92% coverage of query (160 bits)
7u6mC / P06608 Albumin binding domain fused to a mutant of the erwinia asparaginase (see paper)
33% identity, 94% coverage of query (159 bits)
ASPG_DICCH / P06608 L-asparaginase; L-ASNase; L-asparagine amidohydrolase; EC 3.5.1.1 from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 3 papers)
33% identity, 94% coverage of query (159 bits)
Q66CJ2 asparaginase (EC 3.5.1.1) from Yersinia pseudotuberculosis (see 2 papers)
34% identity, 85% coverage of query (158 bits)
fraE / Q8ZLD3 N-(1-deoxy-D-fructos-1-yl)-L-asparaginase (EC 3.5.1.1) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
34% identity, 94% coverage of query (157 bits)
1hg0A X-ray structure of the complex between erwinia chrysanthemi l- asparaginase and succinic acid
33% identity, 94% coverage of query (157 bits)
1jsrA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-l-norleucine
33% identity, 94% coverage of query (157 bits)
1jslA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-d-norleucine
33% identity, 94% coverage of query (157 bits)
1hfwA X-ray structure of the complex between erwinia chrysanthemi l- asparaginase and l-glutamate
32% identity, 94% coverage of query (155 bits)
ASP22_YEAST / P0CX77 L-asparaginase 2-2; L-asparaginase II; L-asparagine amidohydrolase II; ASP II; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
ASP23_YEAST / P0CX78 L-asparaginase 2-3; L-asparaginase II; L-asparagine amidohydrolase II; ASP II; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
ASP24_YEAST / P0CX79 L-asparaginase 2-4; L-asparaginase II; L-asparagine amidohydrolase II; ASP II; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
ASP21_YEAST / P0CZ17 L-asparaginase 2-1; L-asparaginase II; L-asparagine amidohydrolase II; ASP II; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P0CZ17 asparaginase (EC 3.5.1.1) from Saccharomyces cerevisiae (see paper)
30% identity, 98% coverage of query (154 bits)
P38986 asparaginase (EC 3.5.1.1) from Saccharomyces cerevisiae (see paper)
31% identity, 98% coverage of query (154 bits)
P38986 L-asparaginase 1; L-asparaginase I; L-asparagine amidohydrolase I; ASP I; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
31% identity, 98% coverage of query (154 bits)
1hg1A X-ray structure of the complex between erwinia chrysanthemi l- asparaginase and d-aspartate
32% identity, 94% coverage of query (153 bits)
ASPQ_PSEFA / O68897 Glutaminase-asparaginase; L-ASNase/L-GLNase; L-asparagine/L-glutamine amidohydrolase; EC 3.5.1.38 from Pseudomonas fluorescens biotype A (see paper)
32% identity, 89% coverage of query (148 bits)
6pa3A / P00805 E. Coli l-asparaginase ii double mutant (t89v,k162t) in complex with l-asn at ph 7.0 (see paper)
32% identity, 92% coverage of query (145 bits)
ansB / PDB|1AGX_A glutaminase-asparaginase; EC 3.5.1.38 from Acinetobacter glutaminasificans (see 3 papers)
31% identity, 94% coverage of query (144 bits)
Build an alignment for WP_015944362.1 and 38 homologs with ≥ 30% identity
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6wywA Crystal structure of pseudomonas 7a glutaminase-asparaginase in complex with l-asp at ph 4.5
29% identity, 98% coverage of query (141 bits)
6wyyA Crystal structure of pseudomonas 7a glutaminase-asparaginase in complex with l-glu at ph 6.5
28% identity, 98% coverage of query (140 bits)
1zq1A / Q9V0T9 Structure of gatde tRNA-dependent amidotransferase from pyrococcus abyssi (see paper)
30% identity, 97% coverage of query (138 bits)
6wyzA Crystal structure of pseudomonas 7a glutaminase-asparaginase (mutant k173m) in complex with d-glu at ph 5.5
28% identity, 98% coverage of query (138 bits)
1djoA / P10182 Crystal structure of pseudomonas 7a glutaminase-asparaginase with the inhibitor donv covalently bound in the active site (see paper)
29% identity, 89% coverage of query (133 bits)
4pgaA Glutaminase-asparaginase from pseudomonas 7a
29% identity, 89% coverage of query (133 bits)
1djpA Crystal structure of pseudomonas 7a glutaminase-asparaginase with the inhibitor don covalently bound in the active site
29% identity, 89% coverage of query (133 bits)
ASPQ_PSES7 / P10182 Glutaminase-asparaginase; L-ASNase/L-GLNase; L-asparagine/L-glutamine amidohydrolase; PGA; EC 3.5.1.38 from Pseudomonas sp. (strain ATCC 29598 / 7A) (see paper)
29% identity, 89% coverage of query (131 bits)
gatD / O26802 glutamyl-tRNA(Gln) amidotransferase subunit D (EC 6.3.5.7) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see paper)
29% identity, 98% coverage of query (124 bits)
ASPG_THEKO / Q5JIW4 L-asparaginase; L-asparagine amidohydrolase; TkA; TkAsn; EC 3.5.1.1 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 3 papers)
5ot0A / Q5JIW4 The thermostable l-asparaginase from thermococcus kodakarensis (see paper)
31% identity, 98% coverage of query (115 bits)
ASPG1_BACSU / P26900 L-asparaginase 1; L-ASNase 1; L-asparagine amidohydrolase 1; EC 3.5.1.1 from Bacillus subtilis (strain 168) (see paper)
27% identity, 98% coverage of query (109 bits)
4q0mA / Q8TZE8 Crystal structure of pyrococcus furiosus l-asparaginase (see paper)
28% identity, 99% coverage of query (103 bits)
ASPG_PYRFU / Q8TZE8 L-asparaginase; EC 3.5.1.1 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see 6 papers)
Q8TZE8 asparaginase (EC 3.5.1.1) from Pyrococcus furiosus (see 2 papers)
28% identity, 98% coverage of query (101 bits)
ASPG_MYCTU / P9WPX5 L-asparaginase; L-ASNase; L-asparagine amidohydrolase; EC 3.5.1.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
31% identity, 85% coverage of query (98.2 bits)
AnsA / b1767 L-asparaginase 1 (EC 3.5.1.38; EC 3.5.1.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ansA / P0A962 L-asparaginase 1 (EC 3.5.1.38) from Escherichia coli (strain K12) (see 11 papers)
ASPG1_ECOLI / P0A962 L-asparaginase 1; L-asparaginase I; L-ASNase I; L-asparagine amidohydrolase I; EC 3.5.1.1 from Escherichia coli (strain K12) (see paper)
27% identity, 99% coverage of query (89.4 bits)
CA265_RS25090 L-asparaginase (EC 3.5.1.1) from Pedobacter sp. GW460-11-11-14-LB5
26% identity, 97% coverage of query (85.1 bits)
6nxcB / P0A962 Ecai(t162a) mutant in complex with citrate at ph 4 (see paper)
26% identity, 99% coverage of query (84.7 bits)
2himA Crystal structure and allosteric regulation of the cytoplasmic escherichia coli l-asparaginase i
25% identity, 98% coverage of query (82.4 bits)
PfGW456L13_740 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens GW456-L13
26% identity, 81% coverage of query (80.5 bits)
ASPG_DIRIM / Q9U518 L-asparaginase; DiAsp; L-asparagine amidohydrolase; EC 3.5.1.1 from Dirofilaria immitis (Canine heartworm) (see paper)
24% identity, 84% coverage of query (76.6 bits)
4r8lA Crystal structure of the asp-bound guinea pig l-asparaginase 1 catalytic domain
22% identity, 98% coverage of query (76.3 bits)
H0W0T5 asparaginase (EC 3.5.1.1) from Cavia porcellus (see paper)
23% identity, 98% coverage of query (75.9 bits)
Pf1N1B4_2023 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N1B4
24% identity, 98% coverage of query (74.3 bits)
5dndD / H0W0T5 Crystal structure of the asn-bound guinea pig l-asparaginase 1 catalytic domain active site mutant t116a (see paper)
22% identity, 98% coverage of query (74.3 bits)
AO356_11100 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2C3
25% identity, 94% coverage of query (72.8 bits)
AO353_09960 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2E3
25% identity, 95% coverage of query (72.4 bits)
7r6bB / A0A3N4B0Q2 Crystal structure of mutant r43d/l124d/r125a/c273s of l-asparaginase i from yersinia pestis (see paper)
23% identity, 98% coverage of query (71.6 bits)
Pf6N2E2_4087 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2E2
25% identity, 94% coverage of query (69.7 bits)
LPP60_RAT / O88202 60 kDa lysophospholipase; Lysophospholipase-transacylase; EC 3.1.1.5; EC 3.5.1.1; EC 3.1.1.47 from Rattus norvegicus (Rat) (see 3 papers)
22% identity, 98% coverage of query (68.9 bits)
W0G253 asparaginase (EC 3.5.1.1) from Rhizomucor miehei (see paper)
24% identity, 78% coverage of query (65.9 bits)
A0JNU3 1-alkyl-2-acetylglycerophosphocholine esterase (subunit 3/3) (EC 3.1.1.47) from Mus musculus (see paper)
21% identity, 98% coverage of query (65.1 bits)
ASPG / Q86U10 60 kDa lysophospholipase (EC 3.1.1.47; EC 3.5.1.38) from Homo sapiens (see 4 papers)
22% identity, 98% coverage of query (58.5 bits)
A0A1I0U0N3 asparaginase (EC 3.5.1.1) from Pseudomonas otitidis (see paper)
23% identity, 91% coverage of query (54.7 bits)
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Lawrence Berkeley National Laboratory