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Searching for up to 100 curated homologs for WP_015945030.1 NCBI__GCF_000021925.1:WP_015945030.1 (406 a.a.)

Found high-coverage hits (≥70%) to 50 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

XylR / P16557 Transcription factor XylR (repressor) from Bacillus subtilis 168 (see 2 papers)
    30% identity, 94% coverage of query (182 bits)

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Build an alignment for WP_015945030.1 and 1 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

XylR / VIMSS38296 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus subtilis subsp. subtilis str. 168
    29% identity, 90% coverage of query (168 bits)

XylR / VIMSS6926953 XylR regulator of Xylose utilization, effector Xylose (repressor) from Paenibacillus sp. JDR-2
    31% identity, 85% coverage of query (155 bits)

XylR / P70928_BACLI Transcription factor XylR (repressor) from Bacillus licheniformis Gibson 46 (see paper)
    28% identity, 94% coverage of query (153 bits)

XylR / VIMSS730014 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus licheniformis DSM 13
    27% identity, 94% coverage of query (152 bits)

XylR / VIMSS854293 XylR regulator of Xylose utilization, effector Xylose (repressor) from Geobacillus kaustophilus HTA426
    29% identity, 94% coverage of query (150 bits)

XylR / VIMSS3426742 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus pumilus SAFR-032
    28% identity, 95% coverage of query (150 bits)

XylR / VIMSS822024 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus clausii KSM-K16
    30% identity, 79% coverage of query (146 bits)

XylR / VIMSS65339 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus halodurans C-125
    28% identity, 94% coverage of query (139 bits)

5f7qE / Q8YAF1 Rok repressor lmo0178 from listeria monocytogenes bound to operator (see paper)
    26% identity, 93% coverage of query (138 bits)

XylR / VIMSS279908 XylR regulator of Xylose utilization, effector Xylose (repressor) from Oceanobacillus iheyensis HTE831
    27% identity, 94% coverage of query (132 bits)

Q8RDE9 glucokinase (EC 2.7.1.2) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
    27% identity, 77% coverage of query (120 bits)

glcK / P54495 glucokinase (EC 2.7.1.1) from Bacillus subtilis (strain 168) (see paper)
GLK_BACSU / P54495 Glucokinase; Glucose kinase; EC 2.7.1.2 from Bacillus subtilis (strain 168) (see paper)
P54495 glucokinase (EC 2.7.1.2) from Bacillus subtilis (see paper)
    29% identity, 78% coverage of query (115 bits)

NanR / VIMSS6110394 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides plebeius DSM 17135
    25% identity, 81% coverage of query (115 bits)

NagC / VIMSS3566654 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Aeromonas salmonicida subsp. salmonicida A449
    24% identity, 94% coverage of query (112 bits)

glcK / GI|1303865 glucokinase; EC 2.7.1.2 from Bacillus subtilis (see paper)
    28% identity, 78% coverage of query (112 bits)

NagC / VIMSS4630820 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Moritella sp. PE36
    24% identity, 93% coverage of query (109 bits)

NanR / VIMSS6257414 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides eggerthii DSM 20697
    26% identity, 81% coverage of query (109 bits)

Mlc / b1594 DNA-binding transcriptional repressor Mlc from Escherichia coli K-12 substr. MG1655 (see 15 papers)
MLC_ECOLI / P50456 DNA-binding transcriptional repressor Mlc; Making large colonies protein; Membrane linked control from Escherichia coli (strain K12) (see 15 papers)
Mlc / P50456 Transcription factor Mlc (repressor) from Escherichia coli K12 MG1655 (see 4 papers)
mlc / RF|NP_416111.1 protein mlc from Escherichia coli K12 (see 7 papers)
    23% identity, 85% coverage of query (109 bits)

NagC / VIMSS339340 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (activator/repressor) from Vibrio parahaemolyticus RIMD 2210633
    23% identity, 85% coverage of query (107 bits)

5f7rA Rok repressor lmo0178 from listeria monocytogenes bound to inducer
    24% identity, 78% coverage of query (107 bits)

NagC / VIMSS1972937 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Psychromonas ingrahamii 37
    25% identity, 78% coverage of query (104 bits)

NanR / VIMSS3720738 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides vulgatus ATCC 8482
    23% identity, 83% coverage of query (103 bits)

NagC / b0676 DNA-binding transcriptional dual regulator NagC from Escherichia coli K-12 substr. MG1655 (see 14 papers)
NAGC_ECOLI / P0AF20 N-acetylglucosamine repressor from Escherichia coli (strain K12) (see paper)
NagC / P0AF20 Transcription factor NagC (activator/repressor) from Escherichia coli K12 MG1655 (see 3 papers)
nagC / SP|P0AF20 N-acetylglucosamine repressor from Escherichia coli K12 (see paper)
    23% identity, 83% coverage of query (102 bits)

IolR / VIMSS5474541 IolR regulator of Inositol utilization (repressor) from Thermotoga neapolitana DSM 4359
    25% identity, 94% coverage of query (100 bits)

NagC / VIMSS2859304 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Psychromonas sp. CNPT3
    25% identity, 80% coverage of query (100 bits)

1z6rA / P50456 Crystal structure of mlc from escherichia coli (see paper)
    23% identity, 85% coverage of query (100 bits)

1z05A / Q9KQJ1 Crystal structure of the rok family transcriptional regulator, homolog of e.Coli mlc protein.
    24% identity, 84% coverage of query (99.8 bits)

NagC / VIMSS7700176 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Tolumonas auensis DSM 9187
    23% identity, 84% coverage of query (99.0 bits)

XylR / Q9WXW5_THEMA Transcription factor XylR (repressor) from Thermotoga maritima MSB8
    23% identity, 94% coverage of query (95.5 bits)

XylR / VIMSS10362834 XylR regulator of Xylose utilization, effector Xylose; Glucose (repressor) from Thermotoga naphthophila RKU-10
    23% identity, 94% coverage of query (94.0 bits)

NagC / VIMSS79758 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Pasteurella multocida subsp. multocida str. Pm70
    23% identity, 80% coverage of query (93.2 bits)

NagC / VIMSS2773935 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Reinekea sp. MED297
    23% identity, 86% coverage of query (92.0 bits)

NagC / VIMSS548778 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (activator/repressor) from Photorhabdus luminescens TTO1
    22% identity, 80% coverage of query (91.3 bits)

GLK_STRCO / P0A4E1 Glucokinase; Glucose kinase; ORF 3; EC 2.7.1.2 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
P0A4E1 glucokinase (EC 2.7.1.2) from Streptomyces coelicolor (see paper)
glkA glucokinase; EC 2.7.1.2 from Streptomyces coelicolor (see 2 papers)
    29% identity, 70% coverage of query (89.4 bits)

IolR / VIMSS1300 IolR regulator of Inositol utilization (repressor) from Thermotoga maritima MSB8
    22% identity, 95% coverage of query (87.4 bits)

XylR / VIMSS130011 XylR regulator of Xylose utilization, effector Xylose (repressor) from Agrobacterium tumefaciens C58
    25% identity, 78% coverage of query (84.3 bits)

XylR / VIMSS354812 XylR regulator of Xylose utilization, effector Xylose (repressor) from Enterococcus faecalis V583
    24% identity, 95% coverage of query (80.5 bits)

XylR / VIMSS2205864 XylR regulator of Xylose utilization, effector Xylose (repressor) from Rhizobium leguminosarum bv. viciae 3841
    25% identity, 80% coverage of query (80.1 bits)

XylR / VIMSS1781991 XylR regulator of Xylose utilization, effector Xylose (repressor) from Mesorhizobium sp. BNC1
    24% identity, 77% coverage of query (77.8 bits)

CelQ / VIMSS115991 CelQ regulator of Cellobiose utilization, effector Cellobiose-6-phosphate (repressor) from Streptococcus pneumoniae TIGR4
    23% identity, 94% coverage of query (72.4 bits)

ManR / VIMSS5475666 ManR regulator of Mannan and beta-mannosides utilization, effector Mannose (repressor) from Thermotoga neapolitana DSM 4359
    23% identity, 94% coverage of query (71.6 bits)

ManR / Q9X0V1_THEMA Transcription factor ManR (repressor) from Thermotoga maritima MSB8
    24% identity, 94% coverage of query (69.7 bits)

GluR / VIMSS7271596 GluR regulator of Glucose utilization; Trehalose utilization, effector Glucose (repressor) from Thermotoga sp. RQ2
    24% identity, 86% coverage of query (69.7 bits)

XylR / VIMSS85562 XylR regulator of Xylose utilization, effector Xylose (repressor) from Mesorhizobium loti MAFF303099
    22% identity, 80% coverage of query (69.3 bits)

CelQ / VIMSS2059852 CelQ regulator of Cellobiose utilization, effector Cellobiose-6-phosphate (repressor) from Streptococcus sanguinis SK36
    21% identity, 93% coverage of query (67.4 bits)

TreR / VIMSS5474560 TreR regulator of Trehalose utilization, effector Trehalose (repressor) from Thermotoga neapolitana DSM 4359
    22% identity, 94% coverage of query (67.4 bits)

BglR / VIMSS927 BglR regulator of Beta-glucosides utilization, effector Cellobiose (repressor) from Thermotoga maritima MSB8
    26% identity, 82% coverage of query (65.5 bits)

GLK_PYRCJ / A3MUZ0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MUZ0 glucokinase (EC 2.7.1.2) from Pyrobaculum calidifontis (see paper)
    23% identity, 78% coverage of query (64.7 bits)

TreR / VIMSS3678087 TreR regulator of Trehalose utilization, effector Trehalose (repressor) from Thermotoga lettingae TMO
    22% identity, 82% coverage of query (64.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory