Searching for up to 100 curated homologs for WP_017549750.1 NCBI__GCF_000330705.1:WP_017549750.1 (271 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.14.7 / Q9X665 FhuC aka FhuA, component of Iron (Fe3+)-hydroxamate porter (transports Fe3+-ferrichrome and Fe3+-ferrioxamine B with FhuD1, and these compounds plus aerobactin and coprogen with FhuD2) (see 2 papers)
52% identity, 93% coverage of query (277 bits)
fhuC / GI|2832798 ferrichrome transport ATP-binding protein FhuC from Bacillus subtilis (see paper)
45% identity, 96% coverage of query (255 bits)
TC 3.A.1.14.14 / Q9A197 Putative ferrichrome ABC transporter aka SiuA aka Spy0386, component of The Fe3+ /Fe3+ferrichrome/Fe3+heme uptake porter; SiuABDG (FTSABCD) from Streptococcus pyogenes serotype M1 (see 2 papers)
43% identity, 96% coverage of query (239 bits)
FepC / b0588 ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
FepC / P23878 ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) from Escherichia coli (strain K12) (see 3 papers)
FEPC_ECOLI / P23878 Ferric enterobactin transport ATP-binding protein FepC; EC 7.2.2.17 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.2 / P23878 FepC aka B0588, component of Iron (Fe3+)-enterobactin porter from Escherichia coli (see 3 papers)
40% identity, 87% coverage of query (214 bits)
FPUD_BACAN / Q81V82 Petrobactin import ATP-binding protein FpuD; EC 7.2.2.- from Bacillus anthracis (see paper)
40% identity, 91% coverage of query (214 bits)
TC 3.A.1.14.6 / Q9RCF3 ViuC, component of The iron-vibriobactin/enterobactin uptake porter from Vibrio cholerae (see 2 papers)
41% identity, 90% coverage of query (211 bits)
FPUC_BACAN / Q81LM1 Petrobactin import ATP-binding protein FpuC; EC 7.2.2.- from Bacillus anthracis (see paper)
42% identity, 89% coverage of query (211 bits)
YUSV_BACSU / O32188 Probable siderophore transport system ATP-binding protein YusV from Bacillus subtilis (strain 168) (see 2 papers)
38% identity, 93% coverage of query (210 bits)
TC 3.A.1.14.8 / Q8GRB0 PvuE, component of The iron-vibrioferrin uptake porter from Vibrio parahaemolyticus (see paper)
38% identity, 91% coverage of query (208 bits)
FecE / b4287 ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
FecE / P15031 ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) from Escherichia coli (strain K12) (see 2 papers)
FECE_ECOLI / P15031 Fe(3+) dicitrate transport ATP-binding protein FecE; Iron(III) dicitrate transport ATP-binding protein FecE; EC 7.2.2.18 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.1 / P15031 Fe(3+) dicitrate transport ATP-binding protein FecE, component of Iron (Fe3+) or ferric-dicitrate porter from Escherichia coli (strain K12) (see 4 papers)
fecE / GB|AAC77243.1 iron(III) dicitrate transport ATP-binding protein FecE from Escherichia coli K12 (see 6 papers)
39% identity, 91% coverage of query (206 bits)
TC 3.A.1.14.4 / Q47087 CbrD, component of Iron-chrysobactine porter from Erwinia chrysanthemi (see paper)
cbrD / GB|CAA60669.1 achromobactin ABC transporter, ATP-binding protein CbrD from Erwinia chrysanthemi str. 3937 (see paper)
39% identity, 90% coverage of query (206 bits)
TC 3.A.1.14.13 / Q9RK11 CchE, component of Ferric iron-coelichelin uptake porter, CchCDEF from Streptomyces coelicolor (see paper)
42% identity, 93% coverage of query (198 bits)
FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
36% identity, 93% coverage of query (180 bits)
YCLP_BACSU / P94420 Petrobactin import ATP-binding protein YclP; EC 7.2.2.- from Bacillus subtilis (strain 168) (see paper)
36% identity, 87% coverage of query (179 bits)
TC 3.A.1.14.10 / Q99YA4 Putative ABC transporter aka SiaC, component of The heme porter, Shp/SiaABC (HtsABC). Shp is a cell surface heme binding protein that transfers the heme directly to HstA (Nygaard et al., 2006). The crystal structure of the heme binding domain of Shp has been solved (Aranda et al., 2007). HtsABC is required for the uptake of staphyloferrin A (Beasley et al. 2009). The Shp cell surface heme receptor feeds iron-heme to the transporter in preparation for uptake from Streptococcus pyogenes serotype M1 (see 2 papers)
34% identity, 88% coverage of query (176 bits)
TC 3.A.1.14.12 / Q9L177 DesC, component of Desferrioxamine B uptake porter, DesABC from Streptomyces coelicolor (see paper)
36% identity, 86% coverage of query (176 bits)
BTUDA_HALSA / Q9HQ18 Cobalamin import ATP-binding protein BtuD; Vitamin B12-transporting ATPase; EC 7.6.2.8 from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) (see paper)
34% identity, 89% coverage of query (169 bits)
FATE_BACAN / Q81XB3 Petrobactin import ATP-binding protein FatE; EC 7.2.2.- from Bacillus anthracis (see paper)
34% identity, 86% coverage of query (152 bits)
Build an alignment for WP_017549750.1 and 18 homologs with ≥ 30% identity
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TC 3.A.1.14.20 / Q7W025 Hemin import ATP-binding protein HmuV, component of Heme-iron (hemin) utilization transporter BhuTUV from Bordetella pertussis (see paper)
28% identity, 89% coverage of query (139 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
28% identity, 79% coverage of query (111 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
29% identity, 87% coverage of query (106 bits)
1f3oA / Q58206 Crystal structure of mj0796 atp-binding cassette (see paper)
33% identity, 74% coverage of query (105 bits)
1l2tA Dimeric structure of mj0796, a bacterial abc transporter cassette
33% identity, 74% coverage of query (103 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
29% identity, 82% coverage of query (103 bits)
7ahhC Opua inhibited inward-facing, sbd docked
28% identity, 78% coverage of query (103 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
28% identity, 78% coverage of query (103 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
29% identity, 78% coverage of query (102 bits)
7ahdC Opua (e190q) occluded
28% identity, 78% coverage of query (101 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
28% identity, 85% coverage of query (101 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
28% identity, 85% coverage of query (101 bits)
2olkA Abc protein artp in complex with adp-beta-s
28% identity, 85% coverage of query (101 bits)
2oljA Abc protein artp in complex with adp/mg2+
28% identity, 85% coverage of query (101 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
28% identity, 84% coverage of query (96.3 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
28% identity, 83% coverage of query (96.3 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
28% identity, 83% coverage of query (96.3 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
28% identity, 83% coverage of query (96.3 bits)
5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
29% identity, 79% coverage of query (95.1 bits)
8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
29% identity, 79% coverage of query (94.7 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
27% identity, 83% coverage of query (94.4 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
28% identity, 84% coverage of query (94.0 bits)
8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
28% identity, 79% coverage of query (93.6 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
31% identity, 79% coverage of query (92.4 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
28% identity, 83% coverage of query (91.7 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
28% identity, 83% coverage of query (91.7 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
28% identity, 83% coverage of query (91.7 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
28% identity, 83% coverage of query (91.7 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
28% identity, 84% coverage of query (91.7 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
28% identity, 83% coverage of query (91.7 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
30% identity, 78% coverage of query (91.7 bits)
7ch6C / P63386 Cryo-em structure of e.Coli mlafeb with amppnp (see paper)
29% identity, 84% coverage of query (91.7 bits)
6xgyA Crystal structure of e. Coli mlafb abc transport subunits in the dimeric state
30% identity, 81% coverage of query (91.3 bits)
IRTA_MYCS2 / A0R6H8 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
28% identity, 77% coverage of query (90.9 bits)
7cgnB The overall structure of the mlafedb complex in atp-bound eqtall conformation (mutation of e170q on mlaf)
29% identity, 84% coverage of query (90.5 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
28% identity, 83% coverage of query (90.1 bits)
7pruA Structure of ctatm1 in the inward-facing partially occluded with cargo bound
28% identity, 79% coverage of query (89.7 bits)
7pr1A / G0SBE6 Structure of ctatm1 in the occluded conformation with atp bound (see paper)
28% identity, 79% coverage of query (89.4 bits)
1g291 / Q9YGA6 Malk (see paper)
27% identity, 84% coverage of query (89.0 bits)
7mitE / Q63563 Vascular katp channel: kir6.1 sur2b propeller-like conformation 1 (see paper)
29% identity, 80% coverage of query (88.6 bits)
4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
29% identity, 79% coverage of query (88.6 bits)
4fi3C / P06611 Structure of vitamin b12 transporter btucd-f in a nucleotide-bound state (see paper)
27% identity, 82% coverage of query (88.2 bits)
7ch8I Cryo-em structure of p.Aeruginosa mlafebd with adp-v
28% identity, 82% coverage of query (87.8 bits)
4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
29% identity, 79% coverage of query (87.4 bits)
5xu1B / Q8DQF8 Structure of a non-canonical abc transporter from streptococcus pneumoniae r6 (see paper)
31% identity, 74% coverage of query (87.4 bits)
IRTA_MYCT3 / G7CBF5 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
26% identity, 78% coverage of query (87.0 bits)
ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
26% identity, 83% coverage of query (86.7 bits)
8g4cB / O34697 Bceabs atpgs high res tm (see paper)
26% identity, 77% coverage of query (86.7 bits)
5ws4A / A0A0D8G707 Crystal structure of tripartite-type abc transporter macb from acinetobacter baumannii (see paper)
30% identity, 75% coverage of query (85.9 bits)
1l7vC Bacterial abc transporter involved in b12 uptake
27% identity, 82% coverage of query (85.9 bits)
5eg1B / Q9X2W0 Antibacterial peptide abc transporter mcjd with a resolved lipid (see paper)
27% identity, 80% coverage of query (85.5 bits)
5ofrA Structure of the antibacterial peptide abc transporter mcjd in a high energy outward occluded intermediate state
27% identity, 80% coverage of query (85.5 bits)
7tchB Bceab e169q variant atp-bound conformation
26% identity, 77% coverage of query (85.5 bits)
ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
24% identity, 96% coverage of query (84.7 bits)
7zdaC If(apo/asym) conformation of cyddc in adp+pi(cydc)/atp(cydd) bound state (dataset-2)
26% identity, 85% coverage of query (83.6 bits)
7zdkC If(apo/asym) conformation of cyddc in amp-pnp(cydc)/amp-pnp(cydd) bound state (dataset-8)
26% identity, 85% coverage of query (83.6 bits)
7zdfC If(heme/confined) conformation of cyddc in amp-pnp(cydd) bound state (dataset-4)
26% identity, 85% coverage of query (83.6 bits)
8ipsA / P23886 Cryo-em structure of heme transporter cyddc from escherichia coli in the inward facing heme loading state (see paper)
26% identity, 85% coverage of query (83.6 bits)
8j5qD / P9WQJ5 Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- translocation state (see paper)
28% identity, 77% coverage of query (82.8 bits)
8wm7D / Q8YZ75 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
29% identity, 76% coverage of query (82.4 bits)
HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
29% identity, 82% coverage of query (82.4 bits)
7zdtC Occ(apo/return) conformation of cyddc mutant (e500q.C) in atp(cydc) bound state (dataset-18)
26% identity, 85% coverage of query (82.4 bits)
1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
29% identity, 82% coverage of query (82.4 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
24% identity, 83% coverage of query (82.0 bits)
8j5tD Cryo-em structure of mycobacterium tuberculosis oppabcd in the catalytic intermediate state
28% identity, 77% coverage of query (81.6 bits)
8j5sD Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- catalytic intermediate state
28% identity, 77% coverage of query (81.6 bits)
MDR3_HUMAN / P21439 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3; EC 7.6.2.1 from Homo sapiens (Human) (see 28 papers)
TC 3.A.1.201.3 / P21439 Short chain fatty acid phosphatidylcholine translocase (phospholipid flippase), MDR3; AbcB4; Pgy3 from Homo sapiens (Human) (see 15 papers)
25% identity, 83% coverage of query (81.6 bits)
4f4cA / P34712 The crystal structure of the multi-drug transporter (see paper)
25% identity, 84% coverage of query (81.6 bits)
3bk7A / Q9UZA4 Structure of the complete abce1/rnaase-l inhibitor protein from pyrococcus abysii (see paper)
29% identity, 70% coverage of query (81.3 bits)
7y1jA / Q63563 Structure of sur2a in complex with mg-atp and repaglinide in the inward-facing conformation. (see paper)
28% identity, 80% coverage of query (81.3 bits)
8w9mD Cryo-em structure of the cyanobacterial nitrate transporter nrtbcd in complex with atp
29% identity, 76% coverage of query (81.3 bits)
7y1lA Structure of sur2b in complex with mg-atp and repaglinide in the inward-facing conformation
28% identity, 80% coverage of query (80.9 bits)
8jwiA Cryo-em structure of the outward-facing plasmodium falciparum multidrug resistance protein 1
24% identity, 78% coverage of query (80.9 bits)
7zdbC If(heme/bound) conformation of cyddc in adp+pi(cydc)/atp(cydd) bound state (dataset-2)
26% identity, 81% coverage of query (80.5 bits)
7vlsA Structure of sur2b in complex with mgatp/adp and p1075
28% identity, 80% coverage of query (80.5 bits)
7vltA Structure of sur2b in complex with mg-atp/adp and levcromakalim
28% identity, 80% coverage of query (80.5 bits)
7vlrA Structure of sur2b in complex with mg-atp/adp
28% identity, 80% coverage of query (80.5 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
26% identity, 83% coverage of query (80.5 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
26% identity, 83% coverage of query (80.5 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
26% identity, 83% coverage of query (80.5 bits)
8jwfA / Q7K6A5 Cryo-em structure of plasmodium falciparum multidrug resistance protein 1 with h1 helix in complex with mfq (see paper)
24% identity, 78% coverage of query (80.1 bits)
7niwA / P21439 Nanodisc reconstituted human abcb4 in complex with 4b1-fab (posaconazole-bound, inward-open conformation) (see paper)
25% identity, 83% coverage of query (80.1 bits)
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