Searching for up to 100 curated homologs for WP_017597037.1 NCBI__GCF_000341125.1:WP_017597037.1 (536 a.a.)
Found high-coverage hits (≥70%) to 67 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q9X4K7 propionyl-CoA carboxylase (EC 6.4.1.3) from Streptomyces coelicolor (see 2 papers)
79% identity, 97% coverage of query (839 bits)
1xnyA Biotin and propionyl-coa bound to acyl-coa carboxylase beta subunit from s. Coelicolor (pccb)
79% identity, 97% coverage of query (839 bits)
3ib9A / Q9X4K7 Propionyl-coa carboxylase beta subunit, d422l (see paper)
78% identity, 97% coverage of query (836 bits)
PCCB_SACEN / P53003 Propionyl-CoA carboxylase beta chain; PCCase; Propanoyl-CoA:carbon dioxide ligase; EC 6.4.1.3 from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see paper)
75% identity, 100% coverage of query (810 bits)
ACCD5_MYCTU / P9WQH7 Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta5 subunit; Acetyl-CoA carboxylase; ACC; Propionyl-CoA carboxylase; PCC; EC 2.1.3.15; EC 2.1.3.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 6 papers)
70% identity, 98% coverage of query (748 bits)
PCCB_HALMT / I3R7F1 Propionyl-CoA carboxylase, carboxyltransferase subunit; PCC; EC 6.4.1.3 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
I3R7F1 propionyl-CoA carboxylase (subunit 2/3) (EC 6.4.1.3) from Haloferax mediterranei (see paper)
61% identity, 97% coverage of query (650 bits)
5iniF / A0ACI9 Structural basis for acyl-coa carboxylase-mediated assembly of unusual polyketide synthase extender units incorporated into the stambomycin antibiotics (see paper)
61% identity, 97% coverage of query (635 bits)
pccB / Q3J4E3 propionyl-CoA carboxylase β subunit (EC 6.4.1.3) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see paper)
PCCB_CERS4 / Q3J4E3 Propionyl-CoA carboxylase beta chain; PCCase; Propanoyl-CoA:carbon dioxide ligase; EC 6.4.1.3 from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides) (see paper)
59% identity, 96% coverage of query (617 bits)
8pn7A / C5AP75 Engineered glycolyl-coa carboxylase (g20r variant) with bound coa (see paper)
59% identity, 96% coverage of query (610 bits)
Dsui_0517 Propionyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.3) from Dechlorosoma suillum PS
57% identity, 96% coverage of query (607 bits)
3n6rB / Q168G2 Crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) (see paper)
57% identity, 96% coverage of query (604 bits)
PCCB_ROSDO / Q168G2 Propionyl-CoA carboxylase beta chain; EC 6.4.1.3 from Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) (see paper)
57% identity, 96% coverage of query (604 bits)
1vrgA / Q9WZH5 Crystal structure of propionyl-coa carboxylase, beta subunit (tm0716) from thermotoga maritima at 2.30 a resolution
58% identity, 96% coverage of query (601 bits)
Dshi_0718 Propionyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.3) from Dinoroseobacter shibae DFL-12
59% identity, 96% coverage of query (593 bits)
mmdA / Q57079 (S)-methylmalonyl-CoA decarboxylase α subunit (EC 7.2.4.3) from Veillonella parvula (see 5 papers)
MMDA_VEIPA / Q57079 Methylmalonyl-CoA decarboxylase subunit alpha; Carboxyltransferase; EC 7.2.4.3 from Veillonella parvula (Staphylococcus parvulus) (see 8 papers)
TC 3.B.1.1.2 / Q57079 Alpha-subunit,methylmalonyl-CoA decarboxylase, component of Na+-transporting methylmalonyl-CoA decarboxylase from Veillonella parvula (see paper)
AAC36820.1 methylmalonyl-CoA decarboxylase alpha-subunit from Veillonella parvula (see paper)
CAA80872.1 alpha-subunit,methylmalonyl-CoA decarboxylase from Veillonella parvula (see paper)
56% identity, 97% coverage of query (592 bits)
MMDA_PROMO / O54028 Methylmalonyl-CoA decarboxylase subunit alpha; EC 7.2.4.3 from Propionigenium modestum (see paper)
55% identity, 97% coverage of query (592 bits)
mmdA / CAA05137.1 methylmalonyl-CoA decarboxylase, alpha-subunit, partial from Propionigenium modestum (see paper)
55% identity, 96% coverage of query (591 bits)
PCCB_PIG / P79384 Propionyl-CoA carboxylase beta chain, mitochondrial; PCCase subunit beta; Propanoyl-CoA:carbon dioxide ligase subunit beta; EC 6.4.1.3 from Sus scrofa (Pig) (see paper)
55% identity, 95% coverage of query (568 bits)
Q20676 propionyl-CoA carboxylase (subunit 1/2) (EC 6.4.1.3) from Caenorhabditis elegans (see paper)
55% identity, 95% coverage of query (565 bits)
PCCB / P05166 propionyl-CoA carboxylase β chain, mitochondrial (EC 6.4.1.3) from Homo sapiens (see 4 papers)
PCCB_HUMAN / P05166 Propionyl-CoA carboxylase beta chain, mitochondrial; PCCase subunit beta; Propanoyl-CoA:carbon dioxide ligase subunit beta; EC 6.4.1.3 from Homo sapiens (Human) (see 11 papers)
P05166 propionyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.3) from Homo sapiens (see paper)
55% identity, 95% coverage of query (564 bits)
7ybuP / P05166 Human propionyl-coenzyme a carboxylase
55% identity, 95% coverage of query (563 bits)
PCCB_MOUSE / Q99MN9 Propionyl-CoA carboxylase beta chain, mitochondrial; PCCase subunit beta; Propanoyl-CoA:carbon dioxide ligase subunit beta; EC 6.4.1.3 from Mus musculus (Mouse) (see paper)
Q99MN9 propionyl-CoA carboxylase (EC 6.4.1.3) from Mus musculus (see paper)
55% identity, 95% coverage of query (559 bits)
Pccb / P07633 propionyl-CoA carboxylase β subunit (EC 6.4.1.3) from Rattus norvegicus (see 2 papers)
54% identity, 95% coverage of query (555 bits)
pccB / Q877I3 acyl CoA carboxylase carboxyltransferase subunit (EC 2.1.3.15; EC 6.4.1.3; EC 6.3.4.14) from Acidianus brierleyi (see 2 papers)
Q877I3 acetyl-CoA carboxylase (subunit 1/3) (EC 6.4.1.2); propionyl-CoA carboxylase (subunit 2/3) (EC 6.4.1.3) from Acidianus brierleyi (see paper)
pccB / BAC55869.1 carboxyltransferase subunit of acetyl-CoA carboxylase from Acidianus brierleyi (see paper)
52% identity, 96% coverage of query (550 bits)
Caur_3435 / A9WKJ2 propionyl-CoA carboxylase β subunit (EC 6.4.1.3) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
53% identity, 97% coverage of query (548 bits)
Msed_1375 / A4YGI1 acyl CoA carboxylase carboxyltransferase subunit from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see paper)
Q8J2Z5 acetyl-CoA carboxylase (EC 6.4.1.2) from Metallosphaera sedula (see paper)
52% identity, 96% coverage of query (547 bits)
mmdA / Q8GBW6 methylmalonyl-CoA carboxyltransferase 12S subunit (EC 2.1.3.1) from Propionibacterium freudenreichii subsp. shermanii (see 3 papers)
12S_PROFR / Q8GBW6 Methylmalonyl-CoA carboxyltransferase 12S subunit; Transcarboxylase 12S subunit; EC 2.1.3.1 from Propionibacterium freudenreichii subsp. shermanii (see 2 papers)
12S / CAD59919.1 Methylmalonyl-CoA carboxyltransferase 12S subunit from Propionibacterium freudenreichii subsp. shermanii (see paper)
51% identity, 97% coverage of query (521 bits)
1on3E / Q8GBW6 Transcarboxylase 12s crystal structure: hexamer assembly and substrate binding to a multienzyme core (with methylmalonyl-coenzyme a and methylmalonic acid bound) (see paper)
51% identity, 97% coverage of query (521 bits)
ACCD4_MYCTU / O53578 Biotin-dependent long chain acyl-coenzyme A carboxylase beta4 subunit; EC 2.1.3.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
51% identity, 99% coverage of query (513 bits)
1on3C Transcarboxylase 12s crystal structure: hexamer assembly and substrate binding to a multienzyme core (with methylmalonyl-coenzyme a and methylmalonic acid bound)
50% identity, 97% coverage of query (510 bits)
8sgxE / A0A640KR17 Leishmania tarentolae propionyl-coa carboxylase (alpha-4-beta-6) (see paper)
53% identity, 92% coverage of query (509 bits)
AAA25676.1 methylmalonyl-CoA carboxyltransferase subunit 12S monomer from Propionibacterium freudenreichii subsp. shermanii (see paper)
45% identity, 97% coverage of query (407 bits)
ACCD6_MYCTU / P9WQH5 Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta6 subunit; Acetyl-CoA carboxylase; ACC; Propionyl-CoA carboxylase; PCC; EC 2.1.3.15; EC 2.1.3.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
46% identity, 83% coverage of query (353 bits)
4g2rB / P9WQH5 Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor haloxyfop from mycobacterium tuberculosis (see paper)
44% identity, 81% coverage of query (321 bits)
pccB / Q5UWC0 propionyl-CoA carboxylase (EC 6.4.1.3) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see paper)
35% identity, 95% coverage of query (313 bits)
6tzvA Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor phenyl-cyclodiaone from mycobacterium tuberculosis
42% identity, 81% coverage of query (294 bits)
6prwA Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor quizalofop-p derivative from mycobacterium tuberculosis
42% identity, 81% coverage of query (294 bits)
6pk2A Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor quizalofop-p derivative from mycobacterium tuberculosis
42% identity, 81% coverage of query (294 bits)
6p7uA Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor quizalofop-p from mycobacterium tuberculosis
42% identity, 81% coverage of query (294 bits)
6p7uC / P9WQH5 Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor quizalofop-p from mycobacterium tuberculosis
41% identity, 81% coverage of query (286 bits)
6tzvC Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor phenyl-cyclodiaone from mycobacterium tuberculosis
41% identity, 81% coverage of query (286 bits)
6prwC Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor quizalofop-p derivative from mycobacterium tuberculosis
41% identity, 81% coverage of query (286 bits)
6pk2C Crystal structure of the carboxyltransferase subunit of acc (accd6) in complex with inhibitor quizalofop-p derivative from mycobacterium tuberculosis
41% identity, 81% coverage of query (286 bits)
ACCD1_MYCTU / I6YDK7 Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase beta1 subunit; 3-methylcrotonyl-CoA carboxylase; MCC; EC 2.1.3.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
33% identity, 92% coverage of query (245 bits)
Caur_2034 / A9WEI4 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
33% identity, 91% coverage of query (241 bits)
Sama_1361 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) from Shewanella amazonensis SB2B
31% identity, 94% coverage of query (234 bits)
liuB / Q9I297 methylcrotonyl-CoA carboxylase β-subunit (EC 6.4.1.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I297 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Pseudomonas aeruginosa (see paper)
34% identity, 89% coverage of query (233 bits)
3u9sF / Q9I297 Crystal structure of p. Aeruginosa 3-methylcrotonyl-coa carboxylase (mcc) 750 kd holoenzyme, coa complex (see paper)
34% identity, 89% coverage of query (233 bits)
MCCB_DROME / Q9V9A7 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; MCCase subunit beta; 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; EC 6.4.1.4 from Drosophila melanogaster (Fruit fly) (see paper)
31% identity, 94% coverage of query (230 bits)
Psest_1083 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) from Pseudomonas stutzeri RCH2
33% identity, 90% coverage of query (230 bits)
AO356_01585 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2C3
34% identity, 91% coverage of query (227 bits)
Pf6N2E2_2192 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2E2
34% identity, 91% coverage of query (225 bits)
ACCD2_MYCTU / O86318 Probable biotin-dependent acyl-coenzyme A carboxylase beta2 subunit; EC 2.1.3.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
31% identity, 94% coverage of query (225 bits)
SM_b21122 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) from Sinorhizobium meliloti 1021
31% identity, 91% coverage of query (218 bits)
mccB non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase; EC 6.4.1.4 from Emericella nidulans (see paper)
mccB / AAR23111.1 non-biotin containing subunit of 3-methylcrotonyl CoA carboxylase from Aspergillus nidulans (see paper)
32% identity, 91% coverage of query (218 bits)
Q9LDD8 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Arabidopsis thaliana (see 2 papers)
30% identity, 94% coverage of query (218 bits)
8f3dA / A0A640KGP9 3-methylcrotonyl-coa carboxylase in filament, beta-subunit centered (see paper)
32% identity, 89% coverage of query (214 bits)
8rthF / Q385A6 Trypanosoma brucei 3-methylcrotonyl-coa carboxylase (see paper)
31% identity, 92% coverage of query (212 bits)
8j4zJ / Q9HCC0 Human 3-methylcrotonyl-coa carboxylase in bccp-cts state with substrate
30% identity, 90% coverage of query (211 bits)
8k2vG 3-methylcrotonyl-coa carboxylase in mccd state with acetyl coa
30% identity, 90% coverage of query (211 bits)
MCCC2 / Q9HCC0 3-methylcrotonyl-CoA carboxylase β subunit (EC 6.4.1.4) from Homo sapiens (see 4 papers)
MCCB_HUMAN / Q9HCC0 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; MCCase subunit beta; 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; EC 6.4.1.4 from Homo sapiens (Human) (see 14 papers)
31% identity, 90% coverage of query (210 bits)
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atuC / Q9HZV9 cis-geranyl-CoA carboxylase β-subunit (EC 6.4.1.5) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9HZV9 geranoyl-CoA carboxylase (EC 6.4.1.5) from Pseudomonas aeruginosa (see paper)
29% identity, 87% coverage of query (199 bits)
8jxmC / Q9HCC0 Human 3-methylcrotonyl-coa carboxylase in bccp-h2 state with mcoa
28% identity, 90% coverage of query (174 bits)
3gmaB / B7TVP1 Glutaconyl-coa decarboxylase a subunit from clostridium symbiosum co- crystallized with glutaryl-coa (see paper)
24% identity, 98% coverage of query (130 bits)
3gf3A Glutaconyl-coa decarboxylase a subunit from clostridium symbiosum co- crystallized with glutaconyl-coa
23% identity, 98% coverage of query (129 bits)
B7TVP1 glutaconyl-CoA decarboxylase (EC 7.2.4.5) from [Clostridium] symbiosum (see paper)
23% identity, 98% coverage of query (124 bits)
gcdA / Q06700 GcdA (EC 7.2.4.5) from Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) (see 2 papers)
Q06700 glutaconyl-CoA decarboxylase (subunit 4/4) (EC 7.2.4.5) from Acidaminococcus fermentans (see 2 papers)
TC 3.B.1.1.3 / Q06700 GcdA, component of Na+-transporting glutaconyl-CoA decarboxylase from Acidaminococcus fermentans (see 4 papers)
23% identity, 93% coverage of query (99.0 bits)
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Lawrence Berkeley National Laboratory