Searching for up to 100 curated homologs for WP_017598059.1 NCBI__GCF_000341125.1:WP_017598059.1 (455 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q9EYM7 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Streptomyces venezuelae (see paper)
    69% identity, 100% coverage of query (627 bits)

Y1077_MYCTU / P9WP51 Probable cystathionine beta-synthase Rv1077; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    65% identity, 100% coverage of query (584 bits)

7xnzB / P9WP51 Native cystathionine beta-synthase of mycobacterium tuberculosis. (see paper)
    65% identity, 99% coverage of query (580 bits)

7xoyA Cystathionine beta-synthase of mycobacterium tuberculosis in the presence of s-adenosylmethionine and serine.
    65% identity, 99% coverage of query (580 bits)

7qgtB Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with aoaa.
    38% identity, 100% coverage of query (298 bits)

8s5hA / P35520 Full-length human cystathionine beta-synthase with c-terminal 6xhis- tag, basal state, helical reconstruction (see paper)
    40% identity, 88% coverage of query (294 bits)

uptG / AAK53485.1 cystathionine beta-lyase from Xanthomonas campestris pv. campestris (see 4 papers)
    37% identity, 100% coverage of query (293 bits)

CBS / P35520 cystathionine β-synthase monomer (EC 4.2.1.22) from Homo sapiens (see 12 papers)
CBS_HUMAN / P35520 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Homo sapiens (Human) (see 43 papers)
P35520 cystathionine beta-synthase (EC 4.2.1.22) from Homo sapiens (see 18 papers)
    40% identity, 88% coverage of query (293 bits)

4pcuA Crystal structure of delta516-525 e201s human cystathionine beta- synthase with adomet
    37% identity, 100% coverage of query (293 bits)

Cbs / P32232 cystathionine β-synthase subunit (EC 4.2.1.22) from Rattus norvegicus (see 2 papers)
CBS_RAT / P32232 Cystathionine beta-synthase; Beta-thionase; Hemoprotein H-450; Serine sulfhydrase; EC 4.2.1.22 from Rattus norvegicus (Rat) (see 3 papers)
    40% identity, 88% coverage of query (288 bits)

CBS / A0A563XPB1 cystathionine β-synthase (EC 4.2.1.22) from Gallus gallus (see 7 papers)
    41% identity, 94% coverage of query (283 bits)

CYS4 / P32582 Cys4 (EC 4.2.1.22) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
CBS_YEAST / P32582 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; Sulfur transfer protein 4; EC 4.2.1.22 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P32582 cystathionine beta-synthase (EC 4.2.1.22) from Saccharomyces cerevisiae (see 3 papers)
    35% identity, 99% coverage of query (282 bits)

mecA cystathionine beta-synthase; EC 4.2.1.22 from Emericella nidulans (see 2 papers)
    42% identity, 86% coverage of query (280 bits)

5ohxA / Q2V0C9 Structure of active cystathionine b-synthase from apis mellifera (see paper)
    37% identity, 100% coverage of query (257 bits)

CBS_APIME / Q2V0C9 Cystathionine beta-synthase; EC 4.2.1.22 from Apis mellifera (Honeybee) (see paper)
Q2V0C9 cystathionine beta-synthase (EC 4.2.1.22) from Apis mellifera (see paper)
    36% identity, 100% coverage of query (257 bits)

6xwlC / A0A125YSJ9 Cystathionine beta-synthase from toxoplasma gondii (see paper)
    37% identity, 99% coverage of query (256 bits)

6xylA Crystal structure of delta466-491 cystathionine beta-synthase from toxoplasma gondii with l-serine
    37% identity, 99% coverage of query (251 bits)

3pc2A Full length structure of cystathionine beta-synthase from drosophila
    35% identity, 95% coverage of query (251 bits)

3pc3A / Q9VRD9 Full length structure of cystathionine beta-synthase from drosophila in complex with aminoacrylate (see paper)
    35% identity, 95% coverage of query (250 bits)

Q9VRD9 cystathionine beta-synthase (EC 4.2.1.22) from Drosophila melanogaster (see paper)
    35% identity, 95% coverage of query (250 bits)

3pc4A Full length structure of cystathionine beta-synthase from drosophila in complex with serine
    35% identity, 95% coverage of query (250 bits)

6kr5B / Q401L7 Crystal structure of o-acetyl serine sulfhydrylase isoform 3 from entamoeba histolytica (see paper)
    32% identity, 73% coverage of query (155 bits)

5z5cB / Q8REP3 Crystal structure of hydrogen sulfide-producing enzyme (fn1055) from fusobacterium nucleatum: lysine-dimethylated form (see paper)
    30% identity, 71% coverage of query (130 bits)

5b55A Crystal structure of hydrogen sulfide-producing enzyme (fn1055) d232n mutant in complexed with alpha-aminoacrylate intermediate: lysine- dimethylated form
    30% identity, 71% coverage of query (129 bits)

Build an alignment

Build an alignment for WP_017598059.1 and 24 homologs with ≥ 30% identity

Or download the sequences

Additional hits (identity < 30%)

CBS1_CAEEL / G5EFH8 Cystathionine beta-synthase cbs-1; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Caenorhabditis elegans (see 2 papers)
    26% identity, 72% coverage of query (74.3 bits)

Or start over