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Searching for up to 100 curated homologs for WP_018123680.1 NCBI__GCF_000375485.1:WP_018123680.1 (262 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DVU0464 prephenate and/or arogenate dehydrogenase from Desulfovibrio vulgaris Hildenborough JW710
    50% identity, 95% coverage of query (229 bits)

2pv7B / P43902 Crystal structure of chorismate mutase / prephenate dehydrogenase (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution (see paper)
    30% identity, 78% coverage of query (100 bits)

P43902 prephenate dehydrogenase (EC 1.3.1.12) from Haemophilus influenzae (see paper)
    30% identity, 78% coverage of query (100 bits)

Build an alignment

Build an alignment for WP_018123680.1 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

TyrA / b2600 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
tyrA / P07023 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli (strain K12) (see 12 papers)
    28% identity, 94% coverage of query (98.6 bits)

A0A101IGG2 prephenate dehydrogenase (NADP+) (EC 1.3.1.13) from Methanothrix harundinacea (see paper)
    30% identity, 83% coverage of query (94.0 bits)

A8AAX2 prephenate dehydrogenase (NADP+) (EC 1.3.1.13) from Ignicoccus hospitalis (see 2 papers)
    28% identity, 88% coverage of query (78.2 bits)

E1R5M5 arogenate dehydrogenase [NAD(P)+] (EC 1.3.1.79) from Sediminispirochaeta smaragdinae (see paper)
    27% identity, 77% coverage of query (77.0 bits)

O30012 prephenate dehydrogenase (EC 1.3.1.12); prephenate dehydratase (EC 4.2.1.51); chorismate mutase (EC 5.4.99.5) from Archaeoglobus fulgidus (see paper)
    27% identity, 79% coverage of query (76.6 bits)

Q74NC4 prephenate dehydratase (EC 4.2.1.51) from Nanoarchaeum equitans (see paper)
    24% identity, 89% coverage of query (70.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory