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Searching for up to 100 curated homologs for WP_019555704.1 NCBI__GCF_000381085.1:WP_019555704.1 (212 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Pog / b3229 stringent starvation protein A from Escherichia coli K-12 substr. MG1655 (see 8 papers)
TC 1.A.12.3.1 / P0ACA3 The bacterial CLIC homologue, stringent starvation protein A, SspA (212 aas; 0 TMSs) [N-terminal Trx domain; C-terminal glutathione S-transferase (GST) domain] from Escherichia coli (strain K12) (see 5 papers)
sspA stringent starvation protein A from Escherichia coli K12 (see 5 papers)
    48% identity, 97% coverage of query (199 bits)

SSPA_COXBU / Q83AY0 Stringent starvation protein A homolog from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see paper)
    46% identity, 96% coverage of query (182 bits)

4qq7A / B4E6Q3 Crystal structure of putative stringent starvation protein a from burkholderia cenocepacia with bound glutathione
    45% identity, 94% coverage of query (180 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    40% identity, 93% coverage of query (154 bits)

Build an alignment

Build an alignment for WP_019555704.1 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

6wegD Structure of ft (mgla-sspa)-ppgpp-pigr peptide complex
    26% identity, 88% coverage of query (87.0 bits)

6wmtS F. Tularensis rnaps70-(mgla-sspa)-ppgpp-pigr-igla DNA complex (see paper)
    26% identity, 87% coverage of query (85.9 bits)

A0A4Y5QZW9 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    26% identity, 92% coverage of query (70.9 bits)

4yquA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-31
    28% identity, 74% coverage of query (70.5 bits)

6mhbA Glutathione s-transferase omega 1 bound to covalent inhibitor 18
    28% identity, 74% coverage of query (70.1 bits)

3qagA / Q9H4Y5 Human glutathione transferase o2 with glutathione -new crystal form (see paper)
    27% identity, 78% coverage of query (69.3 bits)

3vlnA Human glutathione transferase o1-1 c32s mutant in complex with ascorbic acid
    29% identity, 74% coverage of query (68.9 bits)

GSTO1 / P78417 glutathione transferase, Ω class subunit (EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2) from Homo sapiens (see 2 papers)
GSTO1_HUMAN / P78417 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 5 papers)
P78417 methylarsonate reductase (EC 1.20.4.2); glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 7 papers)
    29% identity, 74% coverage of query (67.8 bits)

6mhcA / P78417 Glutathione s-transferase omega 1 bound to covalent inhibitor 37 (see paper)
    29% identity, 74% coverage of query (67.8 bits)

G7N132 glutathione transferase (EC 2.5.1.18) from Macaca mulatta (see paper)
    27% identity, 83% coverage of query (67.8 bits)

6mhdA Glutathione s-transferase omega 1 bound to covalent inhibitor 44
    29% identity, 74% coverage of query (67.8 bits)

4is0A Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of the non-catalytic ligandin site.
    29% identity, 74% coverage of query (67.8 bits)

4yqvA Glutathione s-transferase omega 1 bound to covalent inhibitor c4-10
    29% identity, 74% coverage of query (67.8 bits)

4yqmA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-27
    29% identity, 74% coverage of query (67.8 bits)

1eemA Glutathione transferase from homo sapiens
    29% identity, 74% coverage of query (67.8 bits)

6pnoA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n- isopropylsulfamoyl)phenyl)acetamide
    29% identity, 74% coverage of query (67.8 bits)

6pnmA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3- (morpholinosulfonyl)phenyl)acetamide
    29% identity, 74% coverage of query (67.8 bits)

5v3qA Human gsto1-1 complexed with ml175
    29% identity, 74% coverage of query (67.8 bits)

5uehA Structure of gsto1 covalently conjugated to quinolinic acid fluorosulfate
    29% identity, 74% coverage of query (67.8 bits)

6pnnA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n-(2- methoxyethyl)-n-methylsulfamoyl)phenyl)acetamide
    29% identity, 74% coverage of query (67.8 bits)

GSTO2_HUMAN / Q9H4Y5 Glutathione S-transferase omega-2; GSTO-2; Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 3 papers)
Q9H4Y5 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 3 papers)
    27% identity, 78% coverage of query (67.4 bits)

6srbB / A0A1M2V359 Crystal structure of glutathione transferase omega 3c from trametes versicolor (see paper)
    25% identity, 92% coverage of query (66.2 bits)

A0A023JBX8 glutathione transferase (EC 2.5.1.18) from Macaca fascicularis (see paper)
    27% identity, 78% coverage of query (66.2 bits)

A0A4Y5QZX3 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 87% coverage of query (65.9 bits)

7dweA / A0A4Y5R087 Crystal structure of a glutathione s-transferase sbgstu7 from salix babylonica in complex with glutathione
    31% identity, 76% coverage of query (65.5 bits)

L7QHV5 glutathione transferase (EC 2.5.1.18) from Oncorhynchus kisutch (see paper)
    27% identity, 76% coverage of query (65.5 bits)

Q9FUT0 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    30% identity, 74% coverage of query (65.5 bits)

A0A4Y5R087 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    31% identity, 76% coverage of query (65.1 bits)

A0A4Y5QZX9 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    32% identity, 73% coverage of query (65.1 bits)

A0A4Y5R2N2 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    31% identity, 72% coverage of query (64.7 bits)

A0A4Y5R2M7 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    25% identity, 87% coverage of query (63.9 bits)

A0A4Y5QZZ8 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    30% identity, 73% coverage of query (63.5 bits)

7zvpA Crystal structure of poplar glutathione transferase u19 in complex with glutathione
    29% identity, 73% coverage of query (63.5 bits)

GSTO1_PIG / Q9N1F5 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Sus scrofa (Pig) (see paper)
    26% identity, 75% coverage of query (63.2 bits)

gst7 / CAB38121.1 GST7 protein from Zea mays (see paper)
    28% identity, 73% coverage of query (63.2 bits)

4gltA / Q1GZF4 Crystal structure of glutathione s-transferase mfla_2116 (target efi- 507160) from methylobacillus flagellatus kt with gsh bound
    28% identity, 76% coverage of query (62.8 bits)

A0A4Y5R032 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    27% identity, 75% coverage of query (62.8 bits)

B3VQJ6 glutathione transferase (EC 2.5.1.18) from Phanerodontia chrysosporium (see paper)
    25% identity, 72% coverage of query (62.8 bits)

A1YW90 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    27% identity, 91% coverage of query (62.4 bits)

7dw4A / A0A4Y5R032 Crystal structure of a glutathione s-transferase mutant sbgstu6(i55t) from salix babylonica in complex with glutathione
    27% identity, 75% coverage of query (62.0 bits)

Q9ZW27 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    27% identity, 74% coverage of query (61.6 bits)

Q8RW04 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    27% identity, 86% coverage of query (61.6 bits)

GSTU5_ARATH / P46421 Glutathione S-transferase U5; AtGSTU5; AtGSTU1; GST class-tau member 5; Glutathione S-transferase 103-1A; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
P46421 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    25% identity, 76% coverage of query (61.2 bits)

Q93WY5 glutathione transferase (EC 2.5.1.18) from Oryza sativa (see 2 papers)
    28% identity, 78% coverage of query (60.8 bits)

5kejA / A0A1P8NWC2 Crystallographic structure of the tau class glutathione s-transferase migstu in complex with s-hexyl-glutathione (see paper)
    24% identity, 75% coverage of query (60.8 bits)

Q84UH6 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Triticum aestivum (see paper)
    26% identity, 88% coverage of query (60.8 bits)

5g5fA Crystallographic structure of the tau class glutathione s-transferase migstu in complex with reduced glutathione.
    24% identity, 75% coverage of query (60.8 bits)

5j4uA / B9I0G5 Crystal structure of a glutathione s-transferase ptgstu30 from populus trichocarpa in complex with gsh
    27% identity, 87% coverage of query (60.5 bits)

8qllA / Q9Z339 Crystal structure of rat glutathione transferase omega 1 bound to glutathione (see paper)
    28% identity, 76% coverage of query (60.5 bits)

Q3MUP2 glutathione transferase (EC 2.5.1.18) from Hordeum vulgare (see paper)
    28% identity, 92% coverage of query (60.1 bits)

GSTU1_ARATH / Q9ZW30 Glutathione S-transferase U1; AtGSTU1; GST class-tau member 1; Glutathione S-transferase 19; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    29% identity, 80% coverage of query (60.1 bits)

A0A4Y5R0K8 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 78% coverage of query (59.7 bits)

D2WL57 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    29% identity, 83% coverage of query (59.3 bits)

A0A4Y5QZX2 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 73% coverage of query (59.3 bits)

Q8RW03 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    28% identity, 72% coverage of query (58.9 bits)

J9WQY6 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Populus tomentosa (see paper)
    26% identity, 85% coverage of query (58.5 bits)

Q8RW02 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    26% identity, 90% coverage of query (58.5 bits)

5agyA / I1MJ34 Crystal structure of a tau class gst mutant from glycine (see paper)
    27% identity, 92% coverage of query (58.2 bits)

DHAR3_ARATH / Q8LE52 Glutathione S-transferase DHAR3, chloroplastic; Chloride intracellular channel homolog 3; CLIC homolog 3; Glutathione-dependent dehydroascorbate reductase 3; AtDHAR3; ChlDHAR; GSH-dependent dehydroascorbate reductase 3; EC 2.5.1.18; EC 1.8.5.1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    25% identity, 88% coverage of query (58.2 bits)

B2ZHM6 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Pinus bungeana (see paper)
    26% identity, 88% coverage of query (57.8 bits)

GSTU24 / Q9SHH6 glutathione S-transferase U24 monomer (EC 2.5.1.18) from Arabidopsis thaliana (see 6 papers)
GSTUO_ARATH / Q9SHH6 Glutathione S-transferase U24; AtGSTU24; GST class-tau member 24; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9SHH6 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    26% identity, 92% coverage of query (57.4 bits)

4kh7B / Q8Z859 Crystal structure of a glutathione transferase family member from salmonella enterica ty2, target efi-507262, with bound glutathione
    24% identity, 79% coverage of query (57.4 bits)

5d9xA Dehydroascorbate reductase complexed with gsh
    26% identity, 88% coverage of query (57.4 bits)

5d9wA Dehydroascorbate reductase (osdhar) complexed with asa
    26% identity, 88% coverage of query (57.4 bits)

5d9vA / Q65XA0 Crystal structure of oxidized dehydroascorbate reductase (osdhar) from oryza sativa l. Japonica (see paper)
    26% identity, 88% coverage of query (56.6 bits)

DHAR1_ORYSJ / Q65XA0 Probable glutathione S-transferase DHAR1, cytosolic; GSH-dependent dehydroascorbate reductase 1; OsDHAR1; Glutathione-dependent dehydroascorbate reductase 1; EC 2.5.1.18; EC 1.8.5.1 from Oryza sativa subsp. japonica (Rice) (see 5 papers)
Q65XA0 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Oryza sativa Japonica Group (see 2 papers)
    26% identity, 88% coverage of query (56.6 bits)

4topA Glycine max glutathione transferase
    26% identity, 92% coverage of query (56.6 bits)

GSTU19 / Q9ZRW8 glutathione S-transferase U19 monomer (EC 2.5.1.18) from Arabidopsis thaliana (see 6 papers)
GSTUJ_ARATH / Q9ZRW8 Glutathione S-transferase U19; AtGSTU19; GST class-tau member 19; Glutathione S-transferase 8; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
Q9ZRW8 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see 3 papers)
    25% identity, 85% coverage of query (56.2 bits)

O49235 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    26% identity, 92% coverage of query (56.2 bits)

5g5aA / Q9SHH7 Glutathione transferase u25 from arabidopsis thaliana in complex with glutathione disulfide
    26% identity, 85% coverage of query (56.2 bits)

Q59721 4-chlorobenzoate dehalogenase (EC 3.8.1.6) from Burkholderia sp. (see paper)
bphK / CAA54033.1 glutathione S-transferase from Paraburkholderia xenovorans LB400 (see paper)
    27% identity, 81% coverage of query (56.2 bits)

2gdrA / Q59721 Crystal structure of a bacterial glutathione transferase (see paper)
    27% identity, 81% coverage of query (55.8 bits)

Q9SHH7 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    26% identity, 85% coverage of query (55.8 bits)

Q8LGN6 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    26% identity, 87% coverage of query (55.8 bits)

2dsaA Ternary complex of bphk, a bacterial gst
    27% identity, 81% coverage of query (55.8 bits)

8jzkA / A0A5N5L538 Crystal structure of glutathione s-transferase tau7 from salix lindleyana in complex with gsh
    29% identity, 70% coverage of query (55.5 bits)

5evoA / U5XYA0 Structure of dehydroascrobate reductase from pennisetum americanum in complex with two non-native ligands, acetate in the g-site and glycerol in the h-site (see paper)
    27% identity, 85% coverage of query (55.1 bits)

DHAR2_ARATH / Q9FRL8 Glutathione S-transferase DHAR2; Chloride intracellular channel homolog 2; CLIC homolog 2; Glutathione-dependent dehydroascorbate reductase 2; AtDHAR2; CytDHAR; GSH-dependent dehydroascorbate reductase 2; EC 2.5.1.18; EC 1.8.5.1 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    24% identity, 88% coverage of query (54.3 bits)

5lolA / Q9FRL8 Glutathione-bound dehydroascorbate reductase 2 of arabidopsis thaliana (see paper)
    24% identity, 88% coverage of query (54.3 bits)

4chsA Crystal structure of a tau class glutathione transferase 10 from glycine max
    27% identity, 91% coverage of query (53.9 bits)

5echB / Q8L7C9 Crystal structure of fin219-fip1 complex with ja and atp (see paper)
    26% identity, 85% coverage of query (53.1 bits)

GSTUK_ARATH / Q8L7C9 Glutathione S-transferase U20; AtGSTU20; FIN219-interacting protein 1; GST class-tau member 20; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    27% identity, 85% coverage of query (53.1 bits)

5myeA / B9HM36 Solution structure of c20s variant of dehydroascorbate reductase 3a from populus trichocarpa in complex with dehydroascorbic acid. (see paper)
    24% identity, 88% coverage of query (50.4 bits)

5n9uA Dehydroascorbate reductase 3a from populus trichocarpa complexed with gsh.
    23% identity, 88% coverage of query (49.3 bits)

3uarA / Q60CN1 Crystal structure of glutathione transferase (target efi-501774) from methylococcus capsulatus str. Bath with gsh bound
    27% identity, 86% coverage of query (48.1 bits)

4mk3A / Q1LJ46 Crystal structure of a glutathione transferase family member from cupriavidus metallidurans ch34, target efi-507362, with bound glutathione sulfinic acid (gso2h)
    24% identity, 88% coverage of query (47.0 bits)

4isdA / C5A7Z5 Crystal structure of glutathione transferase homolog from burkholderia gl bgr1, target efi-501803, with bound glutathione
    26% identity, 91% coverage of query (47.0 bits)

DHAR1_ARATH / Q9FWR4 Glutathione S-transferase DHAR1, mitochondrial; Chloride intracellular channel homolog 1; CLIC homolog 1; Glutathione-dependent dehydroascorbate reductase 1; AtDHAR1; GSH-dependent dehydroascorbate reductase 1; mtDHAR; EC 2.5.1.18; EC 1.8.5.1 from Arabidopsis thaliana (Mouse-ear cress) (see 9 papers)
Q9FWR4 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Arabidopsis thaliana (see paper)
TC 1.A.12.2.1 / Q9FWR4 The plant Cl- intracellular channel protein DHAR1 (glutathione dehydrogenase/dehydroascorbate reductase) from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
DHAR1 / SP|Q9LN37 glutathione S-transferase DHAR1, mitochondrial; EC 1.8.5.1 from Arabidopsis thaliana
    22% identity, 88% coverage of query (46.2 bits)

5elgA / Q9FWR4 The structure of dhar1 from arabidopsis thaliana
    22% identity, 88% coverage of query (46.2 bits)

4jbbA / A6TBY7 Crystal structure of glutathione s-transferase a6tby7(target efi- 507184) from klebsiella pneumoniae mgh 78578, gsh complex
    26% identity, 84% coverage of query (46.2 bits)

5f06A / U5GTL0 Crystal structure of glutathione transferase f7 from populus trichocarpa (see paper)
    25% identity, 71% coverage of query (45.8 bits)

6nv6B Crystal structure of the theta class glutathione s-transferase from the citrus canker pathogen xanthomonas axonopodis pv. Citri with glutathione bound (see paper)
    23% identity, 80% coverage of query (45.4 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    27% identity, 71% coverage of query (45.1 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    27% identity, 71% coverage of query (45.1 bits)

6sraA Crystal structure of glutathione transferase omega 2c from trametes versicolor in complex with naringenin
    22% identity, 93% coverage of query (43.5 bits)

6sr9A Crystal structure of glutathione transferase omega 2c from trametes versicolor in complex with oxyresveratrol
    22% identity, 93% coverage of query (43.5 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory