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Searching for up to 100 curated homologs for WP_019894569.1 NCBI__GCF_000384235.1:WP_019894569.1 (618 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

asnO / Q92W82 N-acetylglutaminylglutamine amide synthase from Rhizobium meliloti (strain 1021) (see paper)
    50% identity, 98% coverage of query (578 bits)

asnB / GB|CAB15032.1 asparagine synthase (glutamine-hydrolysing) 1; EC 6.3.5.4 from Bacillus subtilis (see 4 papers)
    31% identity, 98% coverage of query (285 bits)

ddaH / E2JA33 N-3-fumaroyl-(S)-2,3-diaminopropanoate aminotransferase from Enterobacter agglomerans (see 2 papers)
    32% identity, 98% coverage of query (281 bits)

oxyD / L8EVF2 malonamoyl-CoA synthetase from Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234) (see 3 papers)
    34% identity, 99% coverage of query (273 bits)

asnO / GI|1934835 asparagine synthase (glutamine-hydrolysing) 3; EC 6.3.5.4 from Bacillus subtilis (see 3 papers)
    31% identity, 87% coverage of query (256 bits)

ltsA / BAD83576.1 glutamine amidotransferase from Rhodococcus erythropolis (see paper)
    32% identity, 84% coverage of query (226 bits)

Build an alignment

Build an alignment for WP_019894569.1 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

asnH / Q9CDJ2 peptidoglycan asparagine synthase from Lactococcus lactis subsp. lactis (strain IL1403) (see paper)
    28% identity, 98% coverage of query (222 bits)

ASNH_MYCBO / P64248 Putative asparagine synthetase [glutamine-hydrolyzing]; EC 6.3.5.4 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
    31% identity, 94% coverage of query (216 bits)

CHYD_PENRW / B6HLP8 Amidase chyE; Chrysogine biosynthesis cluster protein D; EC 3.-.-.- from Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum) (see paper)
    27% identity, 91% coverage of query (179 bits)

1ct9A / P22106 Crystal structure of asparagine synthetase b from escherichia coli (see paper)
    29% identity, 82% coverage of query (171 bits)

Q6HA26 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus sylvestris (see paper)
    28% identity, 89% coverage of query (170 bits)

E7EAQ2 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus pinaster (see paper)
    28% identity, 82% coverage of query (169 bits)

D9IXC8 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus pinaster (see paper)
    29% identity, 82% coverage of query (167 bits)

AsnB / b0674 asparagine synthetase B (EC 6.3.5.4; EC 6.3.1.1; EC 3.5.1.38; EC 3.5.1.2) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
asnB / P22106 asparagine synthetase B (EC 6.3.5.4; EC 6.3.1.1; EC 3.5.1.38) from Escherichia coli (strain K12) (see 17 papers)
ASNB_ECOLI / P22106 Asparagine synthetase B [glutamine-hydrolyzing]; AS-B; EC 6.3.5.4 from Escherichia coli (strain K12) (see 6 papers)
asnB asparagine synthetase B, glutamine-hydrolyzing; EC 6.3.5.4 from Escherichia coli (see paper)
    29% identity, 87% coverage of query (167 bits)

Q9SP19 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Helianthus annuus (see paper)
    29% identity, 83% coverage of query (165 bits)

ASNS_SCHPO / P78753 Probable asparagine synthetase [glutamine-hydrolyzing]; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
asn1 / RF|NP_595291.1 asparagine synthetase; EC 6.3.5.4 from Schizosaccharomyces pombe (see 2 papers)
    29% identity, 80% coverage of query (162 bits)

ASNS2_ORYSJ / Q43011 Asparagine synthetase [glutamine-hydrolyzing] 2; Glutamine-dependent asparagine synthetase 2; EC 6.3.5.4 from Oryza sativa subsp. japonica (Rice) (see paper)
Q43011 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Oryza sativa Japonica Group (see paper)
    28% identity, 89% coverage of query (160 bits)

ASNS2_YEAST / P49090 Asparagine synthetase [glutamine-hydrolyzing] 2; Glutamine-dependent asparagine synthetase 2; EC 6.3.5.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    27% identity, 82% coverage of query (146 bits)

A9XS73 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Phaseolus vulgaris (see paper)
    27% identity, 82% coverage of query (145 bits)

Q9SM55 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Phaseolus vulgaris (see paper)
    27% identity, 82% coverage of query (142 bits)

Asns / P49088 asparagine synthetase subunit (EC 6.3.5.4) from Rattus norvegicus (see paper)
    26% identity, 90% coverage of query (132 bits)

ASNS_MOUSE / Q61024 Asparagine synthetase [glutamine-hydrolyzing]; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Mus musculus (Mouse) (see paper)
    26% identity, 90% coverage of query (132 bits)

Q2L9S5 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Bombyx mori (see paper)
    26% identity, 91% coverage of query (119 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory