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Searching for up to 100 curated homologs for WP_019894885.1 NCBI__GCF_000384235.1:WP_019894885.1 (147 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

hisI / CAX46381.1 phosphoribosyl AMP-cyclohydrolase, partial from Chromohalobacter salexigens (see paper)
    62% identity, 93% coverage of query (169 bits)

HIS3_METTH / O26347 Phosphoribosyl-AMP cyclohydrolase; PRA-CH; EC 3.5.4.19 from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) (see paper)
    54% identity, 76% coverage of query (135 bits)

HSERO_RS20310 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) from Herbaspirillum seropedicae SmR1
    56% identity, 70% coverage of query (128 bits)

Q8YH95 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) from Brucella melitensis bv. 1 (see paper)
    51% identity, 71% coverage of query (109 bits)

At-IE / O82768 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19; EC 3.6.1.31) from Arabidopsis thaliana (see paper)
HIS2_ARATH / O82768 Histidine biosynthesis bifunctional protein hisIE, chloroplastic; Protein HISTIDINE BIOSYNTHESIS 2; EC 3.5.4.19; EC 3.6.1.31 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    40% identity, 71% coverage of query (96.3 bits)

7bgmA / A0A072U2X9 Crystal structure of mthisn2, a bifunctional enzyme from the histidine biosynthetic pathway (see paper)
    39% identity, 71% coverage of query (95.5 bits)

7bgnA Crystal structure of mthisn2-amp complex, a bifunctional enzyme from the histidine biosynthetic pathway
    39% identity, 71% coverage of query (95.5 bits)

HIS3_METVA / Q50837 Phosphoribosyl-AMP cyclohydrolase; PRA-CH; EC 3.5.4.19 from Methanococcus vannielii (see paper)
Q50837 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) from Methanococcus vannielii (see paper)
    45% identity, 73% coverage of query (93.6 bits)

HIS2_SCHPO / O59667 Histidine biosynthesis bifunctional protein his7; EC 3.5.4.19; EC 3.6.1.31 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
his7 / GI|3006138 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase His7; EC 3.5.4.19; EC 3.6.1.31 from Schizosaccharomyces pombe (see 2 papers)
    36% identity, 84% coverage of query (63.2 bits)

Build an alignment

Build an alignment for WP_019894885.1 and 9 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory