Searching for up to 100 curated homologs for WP_019895085.1 NCBI__GCF_000384235.1:WP_019895085.1 (547 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
54% identity, 100% coverage of query (607 bits)
als / CAA66718.1 acetolactate synthase from Synechocystis sp (see paper)
52% identity, 100% coverage of query (568 bits)
Q04789 acetolactate synthase (EC 2.2.1.6); branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) from Bacillus subtilis (see 2 papers)
38% identity, 97% coverage of query (401 bits)
4rjiC Acetolactate synthase from bacillus subtilis bound to thdp - crystal form i (see paper)
38% identity, 97% coverage of query (400 bits)
4rjkG Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
38% identity, 97% coverage of query (400 bits)
4rjkF Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
38% identity, 97% coverage of query (400 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
37% identity, 98% coverage of query (360 bits)
Q836A5 acetolactate synthase (EC 2.2.1.6) from Enterococcus faecalis (see 2 papers)
35% identity, 98% coverage of query (353 bits)
Q5M4L0 acetolactate synthase (EC 2.2.1.6) from Streptococcus thermophilus (see paper)
36% identity, 98% coverage of query (346 bits)
5d6rB Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor
36% identity, 97% coverage of query (345 bits)
5dx6B / P27696 Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
37% identity, 98% coverage of query (344 bits)
1ozfA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
36% identity, 97% coverage of query (342 bits)
1ozgA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
36% identity, 98% coverage of query (342 bits)
budB / P27696 catabolic acetolactate synthase (EC 2.2.1.6) from Klebsiella pneumoniae (see 2 papers)
36% identity, 97% coverage of query (341 bits)
5wdgA Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate
36% identity, 97% coverage of query (335 bits)
5dx6A Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
36% identity, 98% coverage of query (333 bits)
als / Q7DAV2 α-acetolactate synthase subunit (EC 2.2.1.6) from Lactococcus lactis subsp. lactis (strain IL1403) (see 2 papers)
Q7DAV2 acetolactate synthase (EC 2.2.1.6) from Lactococcus lactis (see paper)
34% identity, 98% coverage of query (327 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
35% identity, 97% coverage of query (316 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
34% identity, 94% coverage of query (292 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
33% identity, 97% coverage of query (284 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
32% identity, 92% coverage of query (283 bits)
Q5SJ01 acetolactate synthase (EC 2.2.1.6); pyruvate decarboxylase (EC 4.1.1.1) from Thermus thermophilus (see paper)
33% identity, 94% coverage of query (280 bits)
IlvI / b0077 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ilvI / P00893 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli (strain K12) (see 7 papers)
P00893 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
33% identity, 100% coverage of query (280 bits)
G0ZSE6 acetolactate synthase (EC 2.2.1.6) from Pseudomonas sp. (see paper)
33% identity, 97% coverage of query (280 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
31% identity, 97% coverage of query (279 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
33% identity, 97% coverage of query (276 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
33% identity, 97% coverage of query (275 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
31% identity, 96% coverage of query (271 bits)
V5Q0Z4 acetolactate synthase (EC 2.2.1.6) from Myosoton aquaticum (see paper)
33% identity, 97% coverage of query (271 bits)
ilvB / Q0KCU4 acetohydroxyacid synthase subunit B (EC 2.2.1.6) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
32% identity, 100% coverage of query (271 bits)
Q5VB49 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
33% identity, 97% coverage of query (270 bits)
Q5VB44 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
33% identity, 97% coverage of query (270 bits)
5k2oA / P17597 Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, pyrithiobac (see paper)
32% identity, 96% coverage of query (266 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
32% identity, 96% coverage of query (266 bits)
Q5VB42 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
33% identity, 97% coverage of query (266 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
32% identity, 96% coverage of query (266 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
32% identity, 96% coverage of query (266 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
32% identity, 96% coverage of query (266 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
32% identity, 96% coverage of query (266 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
32% identity, 96% coverage of query (266 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
32% identity, 96% coverage of query (266 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
32% identity, 96% coverage of query (266 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
32% identity, 96% coverage of query (266 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
32% identity, 96% coverage of query (266 bits)
1yhzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
32% identity, 96% coverage of query (266 bits)
1yhyA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
32% identity, 96% coverage of query (266 bits)
1ybhA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide chlorimuron ethyl
32% identity, 96% coverage of query (266 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
32% identity, 96% coverage of query (266 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
32% identity, 96% coverage of query (266 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
33% identity, 97% coverage of query (265 bits)
P45261 acetolactate synthase (EC 2.2.1.6) from Haemophilus influenzae (see paper)
30% identity, 100% coverage of query (260 bits)
6vz8D / P17597 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
32% identity, 96% coverage of query (260 bits)
Q42768 acetolactate synthase (EC 2.2.1.6) from Gossypium hirsutum (see paper)
32% identity, 97% coverage of query (259 bits)
Q6K2E8 acetolactate synthase (EC 2.2.1.6) from Oryza sativa (see paper)
31% identity, 97% coverage of query (259 bits)
A5X300 acetolactate synthase (EC 2.2.1.6) from Oryza sativa Indica Group (see paper)
31% identity, 97% coverage of query (259 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
32% identity, 97% coverage of query (256 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
32% identity, 94% coverage of query (254 bits)
Build an alignment for WP_019895085.1 and 57 homologs with ≥ 30% identity
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1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
29% identity, 96% coverage of query (247 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
29% identity, 96% coverage of query (246 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
29% identity, 96% coverage of query (244 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
29% identity, 96% coverage of query (244 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
29% identity, 96% coverage of query (244 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
29% identity, 95% coverage of query (244 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
28% identity, 96% coverage of query (244 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
28% identity, 96% coverage of query (244 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
28% identity, 96% coverage of query (243 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
28% identity, 96% coverage of query (243 bits)
6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl
28% identity, 95% coverage of query (242 bits)
6desA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone
28% identity, 95% coverage of query (242 bits)
6depA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl
28% identity, 95% coverage of query (242 bits)
6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam
28% identity, 95% coverage of query (241 bits)
6demA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl
28% identity, 95% coverage of query (241 bits)
6delA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl
28% identity, 95% coverage of query (241 bits)
6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl
29% identity, 95% coverage of query (240 bits)
6deqA / A0A1D8PJF9 Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam (see paper)
28% identity, 95% coverage of query (238 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
28% identity, 96% coverage of query (234 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
28% identity, 96% coverage of query (233 bits)
6dekA Crystal structure of candida albicans acetohydroxyacid synthase catalytic subunit
28% identity, 95% coverage of query (233 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
28% identity, 96% coverage of query (231 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
28% identity, 96% coverage of query (230 bits)
7egvA Acetolactate synthase from trichoderma harzianum with inhibitor harzianic acid (see paper)
28% identity, 95% coverage of query (228 bits)
2ihvA / Q9LCV9 Carboxyethylarginine synthase from streptomyces clavuligerus: 5- guanidinovaleric acid complex (see paper)
33% identity, 90% coverage of query (226 bits)
2ihuA Carboxyethylarginine synthase from streptomyces clavuligerus: putative reaction intermediate complex
33% identity, 90% coverage of query (226 bits)
2ihuC Carboxyethylarginine synthase from streptomyces clavuligerus: putative reaction intermediate complex
33% identity, 90% coverage of query (226 bits)
ceaS / Q9LCV9 N2-(carboxyethyl)arginine synthase subunit (EC 2.5.1.66) from Streptomyces clavuligerus (see paper)
CEAS_STRCL / Q9LCV9 N(2)-(2-carboxyethyl)arginine synthase; CEA synthetase; CEAS; EC 2.5.1.66 from Streptomyces clavuligerus (see 3 papers)
33% identity, 90% coverage of query (226 bits)
1upaA Carboxyethylarginine synthase from streptomyces clavuligerus (semet structure)
33% identity, 90% coverage of query (226 bits)
6wo1A / Q96VZ6 Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit (see paper)
28% identity, 93% coverage of query (224 bits)
8i01A / P0AEP7 Crystal structure of escherichia coli glyoxylate carboligase (see paper)
30% identity, 94% coverage of query (223 bits)
8i07D Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
29% identity, 94% coverage of query (223 bits)
8i07A Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
29% identity, 94% coverage of query (223 bits)
8beoB Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
30% identity, 94% coverage of query (223 bits)
8beoA Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
30% identity, 94% coverage of query (223 bits)
4feeA High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal b (see paper)
27% identity, 96% coverage of query (196 bits)
1powA The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from lactobacillus plantarum
27% identity, 96% coverage of query (196 bits)
2ezuA Pyruvate oxidase variant f479w in complex with reaction intermediate 2-acetyl-thiamin diphosphate
27% identity, 96% coverage of query (195 bits)
2ez9A Pyruvate oxidase variant f479w in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate
27% identity, 96% coverage of query (195 bits)
2ez8A Pyruvate oxidase variant f479w in complex with reaction intermediate 2-lactyl-thiamin diphosphate
27% identity, 96% coverage of query (195 bits)
2ez4B Pyruvate oxidase variant f479w
27% identity, 96% coverage of query (195 bits)
1y9dD / P37063 Pyruvate oxidase variant v265a from lactobacillus plantarum (see paper)
27% identity, 96% coverage of query (189 bits)
5ahkA / Q4K6F7 Crystal structure of acetohydroxy acid synthase pf5 from pseudomonas protegens
26% identity, 96% coverage of query (186 bits)
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Lawrence Berkeley National Laboratory