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Searching for up to 100 curated homologs for WP_019896063.1 NCBI__GCF_000384235.1:WP_019896063.1 (594 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

O87870 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Thauera aromatica (see paper)
    45% identity, 95% coverage of query (473 bits)

A0L8G4 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Magnetococcus marinus (see paper)
    33% identity, 96% coverage of query (280 bits)

6n2nA / A0L8G4 Crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus (see paper)
    33% identity, 96% coverage of query (279 bits)

6n2oC 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound
    33% identity, 96% coverage of query (279 bits)

6n2oA 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound
    33% identity, 96% coverage of query (279 bits)

korA / B0R3G0 2-oxoglutarate--ferredoxin oxidoreductase α subunit (EC 1.2.7.3) from Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) (see 2 papers)
    36% identity, 81% coverage of query (263 bits)

korA / Q9AJM0 2-oxoglutarate:ferredoxin oxidoreductase α subunit (EC 1.2.7.3) from Hydrogenobacter thermophilus (see paper)
Q9AJM0 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 3 papers)
    33% identity, 95% coverage of query (260 bits)

Build an alignment

Build an alignment for WP_019896063.1 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

ST2300 / P72578 2-oxoacid:ferredoxin oxidoreductase α subunit (EC 1.2.7.11; EC 1.2.7.1; EC 1.2.7.3; EC 1.2.7.7) from Sulfolobus sp. (see 2 papers)
OFOA_SULSP / P72578 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11 from Sulfolobus sp. (see 3 papers)
P72578 2-oxoacid oxidoreductase (ferredoxin) (subunit 2/2) (EC 1.2.7.11) from Sulfolobus sp. (see 2 papers)
    29% identity, 97% coverage of query (217 bits)

OFOA1_SULTO / Q96Y66 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha; OFOR1; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see 2 papers)
Q96Y66 2-oxoacid oxidoreductase (ferredoxin) (subunit 2/2) (EC 1.2.7.11) from Sulfurisphaera tokodaii (see paper)
    29% identity, 97% coverage of query (214 bits)

5b48A / Q96Y66 2-oxoacid:ferredoxin oxidoreductase 1 from sulfolobus tokodai (see paper)
    29% identity, 97% coverage of query (213 bits)

OFOA_SACSO / A0A0E3JT70 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11 from Saccharolobus solfataricus (Sulfolobus solfataricus) (see paper)
    29% identity, 90% coverage of query (213 bits)

Q4J6I9 2-oxoacid oxidoreductase (ferredoxin) (subunit 2/2) (EC 1.2.7.11) from Sulfolobus acidocaldarius (see paper)
    27% identity, 94% coverage of query (189 bits)

5b46A / Q96XT2 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - ligand free form (see paper)
    28% identity, 90% coverage of query (188 bits)

OFOA2_SULTO / Q96XT2 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha; OFOR2; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q96XT2 2-oxoacid oxidoreductase (ferredoxin) (subunit 2/2) (EC 1.2.7.11) from Sulfurisphaera tokodaii (see paper)
    28% identity, 90% coverage of query (188 bits)

5b47A 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - pyruvate complex
    28% identity, 90% coverage of query (188 bits)

OFOA2_AERPE / Q9YBX7 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha; OFOR2; EC 1.2.7.11 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (see paper)
    31% identity, 80% coverage of query (181 bits)

porA / B0R4X6 pyruvate—ferredoxin oxidoreductaseα subunit (EC 1.2.7.1) from Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) (see 10 papers)
    29% identity, 92% coverage of query (178 bits)

korA / O53182 2-oxoglutarate:ferredoxin oxidoreductase α/γ subunit (EC 1.2.7.3) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
KORA_MYCTU / O53182 2-oxoglutarate oxidoreductase subunit KorA; Alpha-ketoglutarate oxidoreductase subunit alpha/gamma; KG oxidoreductase subunit alpha/gamma; KGO subunit alpha/gamma; KOR subunit alpha/gamma; EC 1.2.7.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    32% identity, 75% coverage of query (137 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory