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Searching for up to 100 curated homologs for WP_020173422.1 NCBI__GCF_000385335.1:WP_020173422.1 (355 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

A0T1V9 low-specificity L-threonine aldolase (EC 4.1.2.48) from Sinorhizobium arboris (see paper)
    45% identity, 98% coverage of query (308 bits)

Q59IT3 phenylserine aldolase (EC 4.1.2.26) from Pseudomonas putida (see paper)
GI|62084361 phenylserine aldolase; EC 4.1.2.26 from Pseudomonas putida (see paper)
    44% identity, 98% coverage of query (277 bits)

1v72A / Q59IT3 Crystal structure of phenylserine aldolase from pseudomonas putida
    44% identity, 98% coverage of query (276 bits)

5vyeB / A0A166JNM8 Crystal structure of l-threonine aldolase from pseudomonas putida
    39% identity, 86% coverage of query (231 bits)

Q88R13 L-threonine aldolase (EC 4.1.2.5) from Pseudomonas putida (see paper)
    38% identity, 86% coverage of query (231 bits)

O50584 low-specificity L-threonine aldolase (EC 4.1.2.48) from Pseudomonas sp. (see paper)
    39% identity, 86% coverage of query (229 bits)

O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558)
    39% identity, 86% coverage of query (229 bits)

AO353_07670 L-threonine aldolase (EC 4.1.2.5) from Pseudomonas fluorescens FW300-N2E3
    39% identity, 86% coverage of query (226 bits)

PfGW456L13_1114 L-threonine aldolase (EC 4.1.2.5) from Pseudomonas fluorescens GW456-L13
    39% identity, 86% coverage of query (222 bits)

Build an alignment

Build an alignment for WP_020173422.1 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

GLY1 L-threonine aldolase from Candida albicans (see paper)
    24% identity, 80% coverage of query (58.2 bits)

THA2_ARATH / Q9FPH3 Probable low-specificity L-threonine aldolase 2; Threonine aldolase 2; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    27% identity, 91% coverage of query (56.2 bits)

O13427 low-specificity L-threonine aldolase (EC 4.1.2.48) from Candida albicans (see paper)
    23% identity, 80% coverage of query (56.2 bits)

ltaA / O07051 L-allo-threonine aldolase subunit (EC 4.1.2.48) from Aeromonas jandaei (see paper)
LTAA_AERJA / O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see 2 papers)
O07051 L-allo-threonine aldolase (EC 4.1.2.49) from Aeromonas jandaei (see 4 papers)
ltaA / GB|BAA20404.1 L-allo-threonine aldolase; EC 4.1.2.- from Aeromonas jandaei (see 2 papers)
    27% identity, 71% coverage of query (55.8 bits)

3wgcB / O07051 Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
    27% identity, 71% coverage of query (54.7 bits)

GLY1 / P37303 L-threonine aldolase subunit (EC 4.1.2.48) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
GLY1_YEAST / P37303 Low specificity L-threonine aldolase; Low specificity L-TA; TA; EC 4.1.2.48 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P37303 low-specificity L-threonine aldolase (EC 4.1.2.48) from Saccharomyces cerevisiae (see paper)
    23% identity, 83% coverage of query (54.7 bits)

GLY1 / GB|AAA72430.1 threonine aldolase; EC 4.1.2.5 from Saccharomyces cerevisiae (see paper)
    24% identity, 83% coverage of query (54.3 bits)

GLY1 / CAA06545.1 threonine aldolase from Eremothecium gossypii (see paper)
    25% identity, 82% coverage of query (53.1 bits)

3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase
    26% identity, 80% coverage of query (52.8 bits)

VRTJ_PENAE / D7PHZ0 Aldolase vrtJ; Viridicatumtoxin synthesis protein J; EC 4.1.2.- from Penicillium aethiopicum (see 4 papers)
    25% identity, 88% coverage of query (49.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory