Searching for up to 100 curated homologs for WP_020173974.1 NCBI__GCF_000385335.1:WP_020173974.1 (282 a.a.)
Found high-coverage hits (≥70%) to 79 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CCNA_00003 shikimate dehydrogenase (EC 1.1.1.25) from Caulobacter crescentus NA1000
42% identity, 93% coverage of query (155 bits)
AroE / b3281 shikimate dehydrogenase (EC 1.1.1.25) from Escherichia coli K-12 substr. MG1655 (see 33 papers)
aroE / P15770 shikimate dehydrogenase (EC 1.1.1.25) from Escherichia coli (strain K12) (see 32 papers)
AROE_ECOLI / P15770 Shikimate dehydrogenase (NADP(+)); SD; SDH; EC 1.1.1.25 from Escherichia coli (strain K12) (see 2 papers)
P15770 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Escherichia coli (see 3 papers)
39% identity, 94% coverage of query (154 bits)
1nytA / P15770 Shikimate dehydrogenase aroe complexed with NADP+ (see paper)
39% identity, 94% coverage of query (154 bits)
AROE_STAEQ / Q5HNV1 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Staphylococcus epidermidis (strain ATCC 35984 / RP62A) (see paper)
Q5HNV1 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Staphylococcus epidermidis (see paper)
35% identity, 92% coverage of query (149 bits)
AROE_VIBCH / Q9KVT3 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
38% identity, 93% coverage of query (142 bits)
3pgjA / Q9KVT3 2.49 angstrom resolution crystal structure of shikimate 5- dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. N16961 in complex with shikimate
39% identity, 90% coverage of query (141 bits)
3dooA / Q5HNV1 Crystal structure of shikimate dehydrogenase from staphylococcus epidermidis complexed with shikimate (see paper)
34% identity, 92% coverage of query (139 bits)
Q88RQ5 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Pseudomonas putida (see 2 papers)
38% identity, 93% coverage of query (139 bits)
2hk9B Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with shikimate and NADP+ at 2.2 angstrom resolution
36% identity, 89% coverage of query (138 bits)
2hk9A / O67049 Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with shikimate and NADP+ at 2.2 angstrom resolution (see paper)
36% identity, 89% coverage of query (137 bits)
AROE_AQUAE / O67049 Shikimate dehydrogenase (NADP(+)); SD; SDH; EC 1.1.1.25 from Aquifex aeolicus (strain VF5) (see paper)
O67049 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Aquifex aeolicus (see 2 papers)
36% identity, 89% coverage of query (137 bits)
3sefC / Q9KVT3 2.4 angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. N16961 in complex with shikimate and NADPH
37% identity, 90% coverage of query (132 bits)
3sefA 2.4 angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. N16961 in complex with shikimate and NADPH
38% identity, 90% coverage of query (132 bits)
O27957 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Archaeoglobus fulgidus (see 2 papers)
39% identity, 91% coverage of query (130 bits)
1nvtA / Q58484 Crystal structure of shikimate dehydrogenase (aroe or mj1084) in complex with NADP+ (see paper)
33% identity, 94% coverage of query (129 bits)
aroE / Q58484 shikimate dehydrogenase monomer (EC 1.1.1.25) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
AROE_METJA / Q58484 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
33% identity, 94% coverage of query (129 bits)
1nvtB Crystal structure of shikimate dehydrogenase (aroe or mj1084) in complex with NADP+
33% identity, 94% coverage of query (129 bits)
AROE_GEOKA / Q5KWX7 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Geobacillus kaustophilus (strain HTA426)
37% identity, 94% coverage of query (126 bits)
A4QEK4 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Corynebacterium glutamicum (see paper)
35% identity, 90% coverage of query (122 bits)
Q88IJ7 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Pseudomonas putida KT2440 (see paper)
35% identity, 92% coverage of query (116 bits)
Q9WYI1 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Thermotoga maritima (see 2 papers)
34% identity, 94% coverage of query (111 bits)
AROE_HAEIN / P43876 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
P43876 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Haemophilus influenzae (see paper)
32% identity, 94% coverage of query (110 bits)
AROE_LISMO / Q8Y9N5 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
3tozA / Q8Y9N5 2.2 angstrom crystal structure of shikimate 5-dehydrogenase from listeria monocytogenes in complex with NAD.
31% identity, 88% coverage of query (110 bits)
YdiB / b1692 quinate/shikimate dehydrogenase (EC 1.1.1.282) from Escherichia coli K-12 substr. MG1655 (see 17 papers)
ydiB / P0A6D5 quinate/shikimate dehydrogenase (EC 1.1.1.282) from Escherichia coli (strain K12) (see 14 papers)
YDIB_ECOLI / P0A6D5 Quinate/shikimate dehydrogenase; NAD-dependent shikimate 5-dehydrogenase; EC 1.1.1.282 from Escherichia coli (strain K12) (see 6 papers)
P0A6D5 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Escherichia coli (see paper)
1npdB / P0A6D5 X-ray structure of shikimate dehydrogenase complexed with NAD+ from e.Coli (ydib) northeast structural genomics research consortium (nesg) target er24 (see paper)
ydiB / RF|NP_416207 quinate/shikimate dehydrogenase; EC 1.1.1.282 from Escherichia coli K12 (see 11 papers)
31% identity, 89% coverage of query (110 bits)
3tnlA 1.45 angstrom crystal structure of shikimate 5-dehydrogenase from listeria monocytogenes in complex with shikimate and NAD.
31% identity, 88% coverage of query (110 bits)
1o9bA Quinate/shikimate dehydrogenase ydib complexed with nadh
31% identity, 89% coverage of query (109 bits)
Q6PUF9 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); 3-dehydroquinate dehydratase (EC 4.2.1.10) from Nicotiana tabacum (see paper)
33% identity, 89% coverage of query (108 bits)
2o7sA Crystal structure of the a. Thaliana dhq-dehydroshikimate-sdh- shikimate-NADP(h)
32% identity, 89% coverage of query (105 bits)
2o7qA / Q9SQT8 Crystal structure of the a. Thaliana dhq-dehydroshikimate-sdh- shikimate-NADP(h)
32% identity, 89% coverage of query (104 bits)
1p77A / P43876 Crystal structure of shikimate dehydrogenase (aroe) from haemophilus influenzae (see paper)
32% identity, 94% coverage of query (104 bits)
AROE_THET8 / Q5SJF8 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
Q5SJF8 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Thermus thermophilus (see paper)
2ev9B / Q5SJF8 Crystal structure of shikimate 5-dehydrogenase (aroe) from thermus thermophilus hb8 in complex with NADP(h) and shikimate (see paper)
37% identity, 91% coverage of query (102 bits)
A0A045GU47 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Mycobacterium tuberculosis (see paper)
A5U5Q2 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Mycobacterium tuberculosis (see 2 papers)
P95001 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Mycobacterium tuberculosis (see paper)
33% identity, 96% coverage of query (102 bits)
2cy0A Crystal structure of shikimate 5-dehydrogenase (aroe) from thermus thermophilus hb8 in complex with NADP
37% identity, 91% coverage of query (102 bits)
SHDHL_HAEIN / P44774 Shikimate dehydrogenase-like protein HI_0607; SDH-L; EC 1.1.1.25 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
30% identity, 88% coverage of query (101 bits)
AT3G06350 / Q9SQT8 shikimate dehydrogenase (EC 1.1.1.25; EC 4.2.1.10) from Arabidopsis thaliana (see 3 papers)
DHQSD_ARATH / Q9SQT8 Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic; DHQ-SDH protein; DHQase-SORase; Protein EMBRYO DEFECTIVE 3004; EC 4.2.1.10; EC 1.1.1.25 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9SQT8 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); 3-dehydroquinate dehydratase (EC 4.2.1.10) from Arabidopsis thaliana (see 4 papers)
32% identity, 89% coverage of query (101 bits)
A0A5H2X4C4 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); 3-dehydroquinate dehydratase (EC 4.2.1.10) from Eucalyptus camaldulensis (see paper)
30% identity, 89% coverage of query (100 bits)
A0A168S2B8 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Vitis vinifera (see paper)
31% identity, 89% coverage of query (100 bits)
A0A0A0LQ48 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Cucumis sativus (see paper)
31% identity, 89% coverage of query (100 bits)
Q8ZPR4 Quinate/shikimate dehydrogenase; NAD-dependent shikimate 5-dehydrogenase; EC 1.1.1.282 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
33% identity, 89% coverage of query (100 bits)
A0A5H2WVH6 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Eucalyptus camaldulensis (see paper)
31% identity, 88% coverage of query (99.4 bits)
3jyoA / Q9X5C9 Quinate dehydrogenase from corynebacterium glutamicum in complex with NAD (see paper)
31% identity, 91% coverage of query (99.0 bits)
qsuD / Q9X5C9 quinate/shikimate dehydrogenase monomer (EC 1.1.1.24) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
AROE_CORGL / Q9X5C9 Quinate/shikimate dehydrogenase (NAD(+)); QSDH; EC 1.1.1.-; EC 1.1.1.24 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 2 papers)
Q9X5C9 quinate/shikimate dehydrogenase [NAD(P)+] (EC 1.1.1.282) from Corynebacterium glutamicum (see 2 papers)
31% identity, 91% coverage of query (99.0 bits)
AROE_CORGB / A4QB65 Quinate/shikimate dehydrogenase (NAD(+)); QSDH; EC 1.1.1.-; EC 1.1.1.24 from Corynebacterium glutamicum (strain R) (see paper)
A4QB65 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); quinate/shikimate dehydrogenase [NAD(P)+] (EC 1.1.1.282) from Corynebacterium glutamicum (see 2 papers)
31% identity, 91% coverage of query (99.0 bits)
3jyqA Quinate dehydrogenase from corynebacterium glutamicum in complex with shikimate and nadh
31% identity, 91% coverage of query (99.0 bits)
3jypA Quinate dehydrogenase from corynebacterium glutamicum in complex with quinate and nadh
31% identity, 91% coverage of query (99.0 bits)
4p4gA / I6Y120 Crystal structure of mycobacterium tuberculosis shikimate dehydrogenase
33% identity, 95% coverage of query (98.6 bits)
2gptA Crystal structure of arabidopsis dehydroquinate dehydratase-shikimate dehydrogenase in complex with tartrate and shikimate
35% identity, 89% coverage of query (98.6 bits)
AROE_HELPX / Q56S04 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Helicobacter pylori (Campylobacter pylori) (see paper)
Q56S04 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Helicobacter pylori (see 2 papers)
32% identity, 88% coverage of query (98.2 bits)
A0A168S2G5 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Vitis vinifera (see paper)
30% identity, 88% coverage of query (97.4 bits)
AROE_HELPY / P56119 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
31% identity, 88% coverage of query (96.3 bits)
6bmqA Crystal structure of arabidopsis dehydroquinate dehydratase-shikimate dehydrogenase (t381g mutant) in complex with tartrate and shikimate
34% identity, 89% coverage of query (95.5 bits)
CA265_RS19745 shikimate dehydrogenase (EC 1.1.1.25) from Pedobacter sp. GW460-11-11-14-LB5
36% identity, 88% coverage of query (94.4 bits)
HA49_09215 / A0A095ULP3 5-ketofructose reductase (NADP) monomer (EC 1.1.1.124) from Tatumella morbirosei (see 3 papers)
32% identity, 84% coverage of query (94.0 bits)
4fosA / P56119 Crystal structure of shikimate dehydrogenase (aroe) q237a mutant from helicobacter pylori in complex with shikimate
31% identity, 88% coverage of query (93.6 bits)
3phiA Shikimate 5-dehydrogenase (aroe) from helicobacter pylori in complex with shikimate and NADPH
31% identity, 88% coverage of query (93.6 bits)
Build an alignment for WP_020173974.1 and 55 homologs with ≥ 30% identity
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4k28A / Q88JP1 2.15 angstrom resolution crystal structure of a shikimate dehydrogenase family protein from pseudomonas putida kt2440 in complex with NAD+ (see paper)
29% identity, 85% coverage of query (92.0 bits)
Q88JP1 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); quinate/shikimate dehydrogenase [NAD(P)+] (EC 1.1.1.282) from Pseudomonas putida (see paper)
29% identity, 85% coverage of query (92.0 bits)
7colA Crystal structure of 5-ketofructose reductase complexed with NADPH (see paper)
33% identity, 83% coverage of query (89.4 bits)
3phjA Shikimate 5-dehydrogenase (aroe) from helicobacter pylori in complex with 3-dehydroshikimate
31% identity, 88% coverage of query (88.6 bits)
Q88K85 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); quinate/shikimate dehydrogenase [NAD(P)+] (EC 1.1.1.282) from Pseudomonas putida (see paper)
30% identity, 94% coverage of query (87.0 bits)
A0A168S2H6 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Vitis vinifera (see paper)
28% identity, 89% coverage of query (84.7 bits)
A0A5H2WZU5 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); 3-dehydroquinate dehydratase (EC 4.2.1.10) from Eucalyptus camaldulensis (see paper)
29% identity, 89% coverage of query (81.6 bits)
6hqvA / G0S061 Pentafunctional arom complex from chaetomium thermophilum (see paper)
29% identity, 92% coverage of query (81.3 bits)
A0A3Q7H2B2 quinate/shikimate dehydrogenase [NAD(P)+] (EC 1.1.1.282) from Solanum lycopersicum (see paper)
29% identity, 88% coverage of query (80.5 bits)
Q88GF6 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); quinate/shikimate dehydrogenase [NAD(P)+] (EC 1.1.1.282) from Pseudomonas putida (see paper)
29% identity, 85% coverage of query (80.5 bits)
ARO1 / P08566 pentafunctional AROM polypeptide (EC 4.2.3.4; EC 1.1.1.25; EC 2.7.1.71; EC 2.5.1.19; EC 4.2.1.10) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
ARO1_YEAST / P08566 Pentafunctional AROM polypeptide; EC 4.2.3.4; EC 2.5.1.19; EC 2.7.1.71; EC 4.2.1.10; EC 1.1.1.25 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
29% identity, 91% coverage of query (80.1 bits)
A0A3G3BK08 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Camellia sinensis (see paper)
30% identity, 90% coverage of query (79.7 bits)
A0A5H2WXM2 quinate/shikimate dehydrogenase (NAD+) (EC 1.1.1.24) from Eucalyptus camaldulensis (see paper)
27% identity, 89% coverage of query (76.3 bits)
Q6PUG0 shikimate dehydrogenase (NADP+) (EC 1.1.1.25); 3-dehydroquinate dehydratase (EC 4.2.1.10) from Nicotiana tabacum (see paper)
28% identity, 92% coverage of query (75.9 bits)
A0A6P8EJ47 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Punica granatum (see paper)
32% identity, 88% coverage of query (75.5 bits)
BT4215 shikimate dehydrogenase (EC 1.1.1.25) from Bacteroides thetaiotaomicron VPI-5482
28% identity, 88% coverage of query (75.5 bits)
A0A3Q7IET9 quinate/shikimate dehydrogenase [NAD(P)+] (EC 1.1.1.282) from Solanum lycopersicum (see paper)
28% identity, 90% coverage of query (74.7 bits)
A0A5H2X0F8 quinate/shikimate dehydrogenase (NAD+) (EC 1.1.1.24) from Eucalyptus camaldulensis (see paper)
27% identity, 89% coverage of query (73.9 bits)
ARO1_EMENI / P07547 Pentafunctional AROM polypeptide; EC 4.2.3.4; EC 2.5.1.19; EC 2.7.1.71; EC 4.2.1.10; EC 1.1.1.25 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
P07547 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Aspergillus nidulans (see paper)
aromA pentafunctional AROM polypeptide; EC 1.1.1.25; EC 2.5.1.19; EC 2.7.1.71; EC 4.2.1.10; EC 4.2.3.4 from Emericella nidulans (see 4 papers)
27% identity, 92% coverage of query (73.2 bits)
QUTR_NEUCR / P11637 Transcription factor qa-1s; Quinic acid degradation cluster protein 1s; Quinic acid utilization repressor qa-1s from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 4 papers)
27% identity, 91% coverage of query (73.2 bits)
QUTR_EMENI / Q00784 Quinate repressor protein from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 4 papers)
qutR negative-acting regulatory protein from Emericella nidulans (see paper)
28% identity, 92% coverage of query (67.4 bits)
D7TUX1 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Vitis vinifera (see paper)
29% identity, 90% coverage of query (67.0 bits)
rifI / A0A0H3CYS8 5-amino-3-dehydroquinate dehydrogenase from Amycolatopsis mediterranei (strain U-32) (see 2 papers)
29% identity, 89% coverage of query (53.5 bits)
Q6W3D0 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Toxoplasma gondii (see paper)
22% identity, 71% coverage of query (52.0 bits)
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Lawrence Berkeley National Laboratory