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Searching for up to 100 curated homologs for WP_020176684.1 NCBI__GCF_000385335.1:WP_020176684.1 (484 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4f4fA / Q8YFS0 X-ray crystal structure of plp bound threonine synthase from brucella melitensis
    61% identity, 96% coverage of query (583 bits)

Q8YFS0 threonine synthase (EC 4.2.3.1) from Brucella melitensis (see paper)
    61% identity, 96% coverage of query (582 bits)

AgTHR4 / CAA62506.1 AgTHR4 from Eremothecium gossypii (see paper)
    44% identity, 94% coverage of query (370 bits)

THRC_YEAST / P16120 Threonine synthase; TS; EC 4.2.3.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P16120 threonine synthase (EC 4.2.3.1) from Saccharomyces cerevisiae (see paper)
    44% identity, 87% coverage of query (360 bits)

1kl7A / P16120 Crystal structure of threonine synthase from yeast (see paper)
    44% identity, 87% coverage of query (356 bits)

THRC_CORGL / P23669 Threonine synthase; TS; EC 4.2.3.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
    43% identity, 94% coverage of query (351 bits)

thrC / AAF21130.1 threonine synthase from Methylobacillus flagellatus (see paper)
    41% identity, 95% coverage of query (348 bits)

Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    43% identity, 88% coverage of query (348 bits)

thrC / CAA82670.1 THREONINE SYNTHASE from Corynebacterium glutamicum (see paper)
    42% identity, 94% coverage of query (346 bits)

Q2SWH9 threonine synthase (EC 4.2.3.1) from Burkholderia thailandensis (see paper)
    41% identity, 95% coverage of query (341 bits)

THNS2_HUMAN / Q86YJ6 Threonine synthase-like 2; TSH2; Secreted osteoclastogenic factor of activated T-cells; SOFAT; EC 4.2.3.- from Homo sapiens (Human) (see paper)
    37% identity, 92% coverage of query (306 bits)

THNS2_MOUSE / Q80W22 Threonine synthase-like 2; TSH2; mTSH2; EC 4.2.3.- from Mus musculus (Mouse) (see paper)
    36% identity, 92% coverage of query (290 bits)

PerR / VIMSS78912 PerR regulator of Iron homeostasis; Manganese homeostasis; Oxidative stress response, effector Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide (repressor) from Lactococcus lactis subsp. lactis Il1403
    34% identity, 97% coverage of query (278 bits)

8g1yA / A0A0H2US33 Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
    39% identity, 88% coverage of query (275 bits)

thrC / CAA43214.1 threonine synthase from Serratia marcescens (see paper)
    35% identity, 90% coverage of query (251 bits)

ThrC / b0004 threonine synthase (EC 4.2.3.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
thrC / P00934 threonine synthase (EC 4.2.3.1) from Escherichia coli (strain K12) (see 3 papers)
THRC_ECOLI / P00934 Threonine synthase; TS; EC 4.2.3.1 from Escherichia coli (strain K12) (see paper)
P00934 threonine synthase (EC 4.2.3.1) from Escherichia coli (see paper)
1vb3A / P00934 Crystal structure of threonine synthase from escherichia coli
thrC / GB|BAB96581.1 threonine synthase; EC 4.2.3.1 from Escherichia coli (see paper)
    35% identity, 95% coverage of query (248 bits)

ABZR86_RS15975 threonine synthase (EC 4.2.3.1) from Dyella japonica UNC79MFTsu3.2
    33% identity, 92% coverage of query (193 bits)

Build an alignment

Build an alignment for WP_020176684.1 and 17 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
    23% identity, 79% coverage of query (54.3 bits)

THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    23% identity, 79% coverage of query (53.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory