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Searching for up to 100 curated homologs for WP_020308877.1 NCBI__GCF_000013785.1:WP_020308877.1 (434 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

hom / AAF21129.1 homoserine dehydrogenase from Methylobacillus flagellatus (see paper)
    66% identity, 100% coverage of query (582 bits)

DHOM_NEIG1 / Q5F8J4 Homoserine dehydrogenase; HDH; HSD; NAD(+)-dependent homoserine dehydrogenase; NAD(+)-dependent HSD; NgHSD; EC 1.1.1.3 from Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) (see paper)
    58% identity, 100% coverage of query (480 bits)

D8WXQ1 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
    40% identity, 99% coverage of query (329 bits)

Ga0059261_2711 homoserine dehydrogenase (EC 1.1.1.3) from Sphingomonas koreensis DSMZ 15582
    46% identity, 95% coverage of query (305 bits)

DvMF_1412 homoserine dehydrogenase (EC 1.1.1.3) from Desulfovibrio vulgaris Miyazaki F
    41% identity, 99% coverage of query (303 bits)

DHOM_BACSU / P19582 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Bacillus subtilis (strain 168) (see 3 papers)
P19582 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus subtilis (see paper)
    39% identity, 99% coverage of query (302 bits)

Q56R01 homoserine dehydrogenase (EC 1.1.1.3) from Streptomyces clavuligerus (see paper)
    39% identity, 99% coverage of query (276 bits)

DHOM_CORGL / P08499 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 2 papers)
P08499 homoserine dehydrogenase (EC 1.1.1.3) from Corynebacterium glutamicum (see 2 papers)
    41% identity, 95% coverage of query (276 bits)

DHOM_LACLC / P52985 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Lactococcus lactis subsp. cremoris (Streptococcus cremoris) (see paper)
    36% identity, 92% coverage of query (267 bits)

6dzsA / K5BJC9 Mycobacterial homoserine dehydrogenase thra in complex with NADP
    40% identity, 98% coverage of query (265 bits)

A0A0H2WVX4 homoserine dehydrogenase (EC 1.1.1.3) from Staphylococcus aureus (see 2 papers)
    40% identity, 77% coverage of query (254 bits)

P46806 homoserine dehydrogenase (EC 1.1.1.3) from Mycobacterium leprae (see paper)
    39% identity, 100% coverage of query (238 bits)

D8WXQ2 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
    36% identity, 78% coverage of query (226 bits)

4pg7A / A0A0M3KKV6 Crystal structure of s. Aureus homoserine dehydrogenase at ph7.5 (see paper)
    38% identity, 77% coverage of query (225 bits)

Q9WZ17 homoserine dehydrogenase (EC 1.1.1.3); aspartate kinase (EC 2.7.2.4) from Thermotoga maritima (see paper)
    43% identity, 73% coverage of query (215 bits)

Build an alignment

Build an alignment for WP_020308877.1 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory