Searching for up to 100 curated homologs for WP_022947301.1 NCBI__GCF_000421465.1:WP_022947301.1 (278 a.a.)

Found high-coverage hits (≥70%) to 32 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SERB_POLSJ / Q12A06 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
    45% identity, 79% coverage of query (175 bits)

SERB_ALBFT / Q21YU0 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Rhodoferax ferrireducens) (see paper)
    47% identity, 72% coverage of query (169 bits)

SERB_IDILO / Q5QXU4 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) (see paper)
    49% identity, 73% coverage of query (166 bits)

7qplA / Q8YI30 Crystal structure of phosphoserine phosphatase (serb) from brucella melitensis in complex with phosphate and magnesium
    44% identity, 74% coverage of query (160 bits)

SERB_STRCO / Q9S281 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    45% identity, 75% coverage of query (150 bits)

1f5sA / Q58989 Crystal structure of phosphoserine phosphatase from methanococcus jannaschii (see paper)
    39% identity, 74% coverage of query (150 bits)

SERB_METJA / Q58989 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58989 phosphoserine phosphatase (EC 3.1.3.3) from Methanocaldococcus jannaschii (see 4 papers)
    39% identity, 74% coverage of query (150 bits)

1l7nA Transition state analogue of phosphoserine phosphatase (aluminum fluoride complex)
    39% identity, 74% coverage of query (150 bits)

SERB2_MYCTU / O53289 Phosphoserine phosphatase SerB2; PSP; PSPase; O-phosphoserine phosphohydrolase; Protein-serine/threonine phosphatase; EC 3.1.3.3; EC 3.1.3.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
O53289 phosphoserine phosphatase (EC 3.1.3.3) from Mycobacterium tuberculosis (see 2 papers)
    43% identity, 76% coverage of query (149 bits)

1l7pA Substrate bound phosphoserine phosphatase complex structure
    39% identity, 74% coverage of query (148 bits)

SerB / b4388 phosphoserine phosphatase (EC 3.1.3.3) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
serB / P0AGB0 phosphoserine phosphatase (EC 3.1.3.3) from Escherichia coli (strain K12) (see 10 papers)
SERB_ECOLI / P0AGB0 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Escherichia coli (strain K12) (see paper)
serB phosphoserine phosphatase; EC 3.1.3.3 from Escherichia coli K12 (see paper)
    39% identity, 89% coverage of query (147 bits)

8a1zA / A0QJI1 Crystal structure of phosphoserine phosphatase serb from mycobacterium avium in complex with 1-(2,4-dichlorophenyl)-3-hydroxyurea (see paper)
    41% identity, 85% coverage of query (144 bits)

SERB_MYCA1 / A0QJI1 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Mycobacterium avium (strain 104) (see paper)
    41% identity, 85% coverage of query (144 bits)

5jlpA Crystal structure of mycobacterium avium serb2 in complex with serine at act domain
    41% identity, 85% coverage of query (144 bits)

8a21A Crystal structure of phosphoserine phosphatase serb from mycobacterium avium in complex with phenylimidazole
    41% identity, 85% coverage of query (144 bits)

SERB_STRT2 / Q5M3B3 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
    43% identity, 74% coverage of query (142 bits)

SERB_WOLSU / Q7M7U5 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes) (see paper)
    40% identity, 74% coverage of query (135 bits)

1l7oA Crystal structure of phosphoserine phosphatase in apo form
    37% identity, 74% coverage of query (133 bits)

SERB_LACLA / Q9CHW3 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) (see paper)
    38% identity, 71% coverage of query (132 bits)

SERB_YEAST / P42941 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    37% identity, 76% coverage of query (130 bits)

SERB_CAMJD / A7H590 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97) (see paper)
    35% identity, 74% coverage of query (117 bits)

3m1yC / O25367 Crystal structure of a phosphoserine phosphatase (serb) from helicobacter pylori
    34% identity, 75% coverage of query (107 bits)

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Build an alignment for WP_022947301.1 and 22 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

PSPH / P78330 L-3-phosphoserine phosphatase (EC 3.1.3.3) from Homo sapiens (see 6 papers)
SERB_HUMAN / P78330 Phosphoserine phosphatase; PSP; PSPase; L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Homo sapiens (Human) (see 7 papers)
P78330 phosphoserine phosphatase (EC 3.1.3.3) from Homo sapiens (see 3 papers)
    29% identity, 72% coverage of query (68.6 bits)

1l8oA Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
    29% identity, 72% coverage of query (68.6 bits)

1l8lA Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase
    29% identity, 72% coverage of query (68.6 bits)

6hyjB / P78330 Psph human phosphoserine phosphatase (see paper)
    29% identity, 72% coverage of query (68.2 bits)

6q6jB Human phosphoserine phosphatase with substrate analogue homo-cysteic acid
    29% identity, 72% coverage of query (68.2 bits)

6hyyA Human phosphoserine phosphatase with serine and phosphate
    29% identity, 72% coverage of query (68.2 bits)

Q5M819 phosphoserine phosphatase (EC 3.1.3.3) from Rattus norvegicus (see paper)
    28% identity, 72% coverage of query (63.5 bits)

Q99LS3 phosphoserine phosphatase (EC 3.1.3.3) from Mus musculus (see paper)
    28% identity, 72% coverage of query (62.8 bits)

SERC_ARATH / O82796 Phosphoserine phosphatase, chloroplastic; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    28% identity, 75% coverage of query (56.2 bits)

C5H3W0 glycerol-3-phosphate dehydrogenase (NAD+) (EC 1.1.1.8) from Dunaliella viridis (see paper)
    24% identity, 72% coverage of query (50.8 bits)

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