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Searching for up to 100 curated homologs for WP_026127746.1 NCBI__GCF_000341125.1:WP_026127746.1 (374 a.a.)

Found high-coverage hits (≥70%) to 40 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SERC_MYCTU / P9WQ73 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WQ73 phosphoserine transaminase (EC 2.6.1.52) from Mycobacterium tuberculosis (see paper)
    66% identity, 100% coverage of query (513 bits)

2fyfA / P9WQ73 Structure of a putative phosphoserine aminotransferase from mycobacterium tuberculosis (see paper)
    66% identity, 99% coverage of query (509 bits)

Build an alignment

Build an alignment for WP_026127746.1 and 2 homologs with ≥ 30% identity

Select sequences

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Additional hits (identity < 30%)

3ffrA Crystal structure of a phosphoserine aminotransferase serc (chu_0995) from cytophaga hutchinsonii atcc 33406 at 1.75 a resolution
    26% identity, 93% coverage of query (109 bits)

5yb0B / Q60I38 Crystal structure of wild type phosphoserine aminotransferase (psat) from e. Histolytica (see paper)
    23% identity, 94% coverage of query (91.7 bits)

serC / Q8TNI1 phosphoserine aminotransferase monomer (EC 2.6.1.52; EC 2.6.1.1) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see 2 papers)
    24% identity, 95% coverage of query (80.9 bits)

SERC_METBF / P52878 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Methanosarcina barkeri (strain Fusaro / DSM 804) (see paper)
P52878 phosphoserine transaminase (EC 2.6.1.52) from Methanosarcina barkeri (see paper)
    23% identity, 95% coverage of query (75.5 bits)

Q2F5M8 phosphoserine transaminase (EC 2.6.1.52) from Bombyx mori (see paper)
    23% identity, 94% coverage of query (63.2 bits)

V9NC98 phosphoserine transaminase (EC 2.6.1.52) from Acanthamoeba castellanii (see paper)
    23% identity, 87% coverage of query (62.4 bits)

SERC_NIACI / Q59196 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Niallia circulans (Bacillus circulans) (see 2 papers)
Q59196 phosphoserine transaminase (EC 2.6.1.52) from Niallia circulans (see paper)
serC / CAA86558.2 phosphoserine aminotransferase from Bacillus circulans subsp. alkalophilus (see paper)
    23% identity, 90% coverage of query (62.0 bits)

PSAT1 / Q9Y617 Phosphoserine aminotransferase (EC 2.6.1.52) from Homo sapiens (see 2 papers)
SERC_HUMAN / Q9Y617 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Homo sapiens (Human) (see 7 papers)
Q9Y617 glycine transaminase (EC 2.6.1.4); phosphoserine transaminase (EC 2.6.1.52) from Homo sapiens (see 5 papers)
    23% identity, 93% coverage of query (62.0 bits)

1bt4A / Q59196 Phosphoserine aminotransferase from bacillus circulans subsp. Alkalophilus
    23% identity, 90% coverage of query (62.0 bits)

8a5vE / Q9Y617 Crystal structure of the human phosposerine aminotransferase (psat) (see paper)
    23% identity, 93% coverage of query (61.6 bits)

8a5wC Crystal structure of the human phosphoserine aminotransferase (psat) in complex with o-phosphoserine
    23% identity, 93% coverage of query (61.6 bits)

8a5wA Crystal structure of the human phosphoserine aminotransferase (psat) in complex with o-phosphoserine
    23% identity, 93% coverage of query (61.6 bits)

8a5vA Crystal structure of the human phosposerine aminotransferase (psat)
    23% identity, 93% coverage of query (61.6 bits)

2dr1A / O59033 Crystal structure of the ph1308 protein from pyrococcus horikoshii ot3
    21% identity, 97% coverage of query (60.8 bits)

AGT1_RABIT / P31030 Alanine--glyoxylate aminotransferase; AGT; Serine--pyruvate aminotransferase; SPT; EC 2.6.1.44; EC 2.6.1.51 from Oryctolagus cuniculus (Rabbit) (see paper)
    26% identity, 80% coverage of query (59.3 bits)

1iugA / P83786 The crystal structure of aspartate aminotransferase which belongs to subgroup iv from thermus thermophilus (see paper)
    26% identity, 84% coverage of query (57.8 bits)

4azjA / Q9RME2 Structural basis of l-phosphoserine binding to bacillus alcalophilus phosphoserine aminotransferase (see paper)
    19% identity, 90% coverage of query (57.8 bits)

8a5wE Crystal structure of the human phosphoserine aminotransferase (psat) in complex with o-phosphoserine
    23% identity, 93% coverage of query (57.8 bits)

SERC_ALKAL / Q9RME2 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Alkalihalobacillus alcalophilus (Bacillus alcalophilus) (see 3 papers)
Q9RME2 phosphoserine transaminase (EC 2.6.1.52) from Alkalihalobacillus alcalophilus (see paper)
    19% identity, 90% coverage of query (57.4 bits)

3kgwB / O35423 Crystal structure of putative aminotransferase (aah25799.1) from mus musculus at 1.65 a resolution
    25% identity, 83% coverage of query (57.4 bits)

3e77A Human phosphoserine aminotransferase in complex with plp
    23% identity, 87% coverage of query (57.4 bits)

Agxt / P09139 serine-pyruvate aminotransferase, mitochondrial subunit (EC 2.6.1.51) from Rattus norvegicus (see 5 papers)
AGT1_RAT / P09139 Alanine--glyoxylate aminotransferase; AGT; Serine--pyruvate aminotransferase, mitochondrial; SPT; EC 2.6.1.44; EC 2.6.1.51 from Rattus norvegicus (Rat) (see 3 papers)
    24% identity, 83% coverage of query (56.6 bits)

3kgxA Crystal structure of putative aminotransferase (aah25799.1) from mus musculus at 1.80 a resolution
    24% identity, 83% coverage of query (56.6 bits)

1w23B Crystal structure of phosphoserine aminotransferase from bacillus alcalophilus
    19% identity, 90% coverage of query (54.3 bits)

SERC_DROME / Q9VAN0 Probable phosphoserine aminotransferase; PSAT; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Drosophila melanogaster (Fruit fly) (see paper)
    22% identity, 94% coverage of query (53.5 bits)

6czyA / Q96255 Crystal structure of arabidopsis thaliana phosphoserine aminotransferase isoform 1 (atpsat1) in complex with pyridoxamine-5'- phosphate (pmp) (see paper)
    22% identity, 93% coverage of query (50.1 bits)

6czzA Crystal structure of arabidopsis thaliana phosphoserine aminotransferase isoform 1 (atpsat1) in complex with plp- phosphoserine geminal diamine intermediate
    22% identity, 93% coverage of query (50.1 bits)

PSAT / Q96255 phosphoserine aminotransferase (EC 2.6.1.52) from Arabidopsis thaliana (see paper)
SERB1_ARATH / Q96255 Phosphoserine aminotransferase 1, chloroplastic; AtPSAT1; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q96255 phosphoserine transaminase (EC 2.6.1.52) from Arabidopsis thaliana (see 3 papers)
    22% identity, 93% coverage of query (49.7 bits)

1j04A / P21549 Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro (see paper)
    24% identity, 82% coverage of query (49.3 bits)

3qboB Crystal structure of phosphoserine aminotransferase from yersinia pestis co92
    23% identity, 72% coverage of query (48.9 bits)

A2V838 alanine-glyoxylate transaminase (EC 2.6.1.44) from Homo sapiens (see 2 papers)
    25% identity, 82% coverage of query (48.1 bits)

SERC_SPIOL / P52877 Phosphoserine aminotransferase, chloroplastic; PSAT; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Spinacia oleracea (Spinach) (see paper)
    22% identity, 78% coverage of query (47.8 bits)

sgaA / O08374 serine-glyoxylate aminotransferase subunit (EC 2.6.1.45) from Hyphomicrobium methylovorum (see 2 papers)
SGAA_HYPME / O08374 Serine--glyoxylate aminotransferase; SGAT; EC 2.6.1.45 from Hyphomicrobium methylovorum (see paper)
    25% identity, 77% coverage of query (47.4 bits)

6xdkD / B2FKF0 Crystal structure of phosphoserine aminotransferase (serc) from stenotrophomonas maltophilia k279a
    24% identity, 72% coverage of query (47.4 bits)

AGXT1 / P21549 Serine--pyruvate aminotransferase (EC 2.6.1.44; EC 2.6.1.51) from Homo sapiens (see 6 papers)
AGT1_HUMAN / P21549 Alanine--glyoxylate aminotransferase; AGT; Serine--pyruvate aminotransferase; SPT; EC 2.6.1.44; EC 2.6.1.51 from Homo sapiens (Human) (see 26 papers)
    23% identity, 82% coverage of query (47.0 bits)

5hhyA Structure of human alanine:glyoxylate aminotransferase major allele (agt-ma) showing x-ray induced reduction of plp internal aldimine to 4'-deoxy-piridoxine-phosphate (plr)
    23% identity, 82% coverage of query (47.0 bits)

6rv0A Human alanine:glyoxylate aminotransferase major allele (agt-ma); with pmp in the active site
    23% identity, 82% coverage of query (47.0 bits)

1h0cA The crystal structure of human alanine:glyoxylate aminotransferase
    23% identity, 82% coverage of query (46.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory