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Searching for up to 100 curated homologs for WP_026595791.1 NCBI__GCF_000385335.1:WP_026595791.1 (667 a.a.)

Found high-coverage hits (≥70%) to 35 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

pccA / Q3J4D9 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see paper)
    56% identity, 100% coverage of query (710 bits)

PCCA_RUEPO / Q5LUF3 Propionyl-CoA carboxylase alpha chain; EC 6.4.1.3 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
Q5LUF3 propionyl-CoA carboxylase (EC 6.4.1.3) from Ruegeria pomeroyi (see paper)
    54% identity, 100% coverage of query (705 bits)

Dshi_0723 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dinoroseobacter shibae DFL-12
    54% identity, 100% coverage of query (689 bits)

3n6rG / Q5LUF3 Crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) (see paper)
    54% identity, 100% coverage of query (687 bits)

Dsui_0516 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dechlorosoma suillum PS
    55% identity, 100% coverage of query (671 bits)

7ybuA / P05165 Human propionyl-coenzyme a carboxylase
    48% identity, 100% coverage of query (614 bits)

PCCA / P05165 propionyl-CoA carboxylase α chain, mitochondrial (EC 6.4.1.3) from Homo sapiens (see 4 papers)
PCCA_HUMAN / P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Homo sapiens (Human) (see 11 papers)
P05165 propionyl-CoA carboxylase (subunit 1/2) (EC 6.4.1.3) from Homo sapiens (see paper)
    48% identity, 100% coverage of query (613 bits)

PCCA_PIG / P0DTA4 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Sus scrofa (Pig) (see paper)
    47% identity, 100% coverage of query (602 bits)

PCCA_MOUSE / Q91ZA3 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Mus musculus (Mouse) (see paper)
    48% identity, 100% coverage of query (602 bits)

Pcca / P14882 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Rattus norvegicus (see paper)
    47% identity, 100% coverage of query (592 bits)

3n6rA / Q5LUF3 Crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) (see paper)
    48% identity, 100% coverage of query (561 bits)

PCCA_CAEEL / Q19842 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Caenorhabditis elegans (see paper)
Q19842 propionyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.3) from Caenorhabditis elegans (see paper)
    44% identity, 100% coverage of query (545 bits)

8sgxX / A0A640KC69 Leishmania tarentolae propionyl-coa carboxylase (alpha-4-beta-6) (see paper)
    45% identity, 99% coverage of query (544 bits)

MCCC1 / Q96RQ3 3-methylcrotonyl-CoA carboxylase α subunit (EC 6.4.1.4) from Homo sapiens (see 4 papers)
MCCA_HUMAN / Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Homo sapiens (Human) (see 15 papers)
    41% identity, 100% coverage of query (497 bits)

MCCA_MOUSE / Q99MR8 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Mus musculus (Mouse) (see paper)
    41% identity, 100% coverage of query (488 bits)

MCCA_ARATH / Q42523 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q42523 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Arabidopsis thaliana (see 2 papers)
    42% identity, 98% coverage of query (486 bits)

atuF / Q9HZV6 cis-geranyl-CoA carboxylase α-subunit (EC 6.4.1.5) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    43% identity, 100% coverage of query (478 bits)

SM_b21124 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Sinorhizobium meliloti 1021
    45% identity, 98% coverage of query (476 bits)

8j78I / Q96RQ3 Human 3-methylcrotonyl-coa carboxylase in bccp-h2 state
    39% identity, 100% coverage of query (454 bits)

Sama_1359 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Shewanella amazonensis SB2B
    41% identity, 100% coverage of query (450 bits)

AO356_01595 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2C3
    43% identity, 100% coverage of query (449 bits)

Pf6N2E2_2194 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2E2
    42% identity, 100% coverage of query (448 bits)

liuD / Q9I299 methylcrotonyl-CoA carboxylase α-subunit (EC 6.4.1.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I299 methylcrotonoyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.4) from Pseudomonas aeruginosa (see 3 papers)
    43% identity, 100% coverage of query (442 bits)

8rthA / Q57YQ4 Trypanosoma brucei 3-methylcrotonyl-coa carboxylase (see paper)
    40% identity, 99% coverage of query (433 bits)

PCCA_HALMT / I3R7G3 Propionyl-CoA carboxylase, biotin carboxylase and biotin-carboxyl carrier subunit; PCC; EC 6.4.1.3; EC 6.3.4.14 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
I3R7G3 propionyl-CoA carboxylase (subunit 3/3) (EC 6.4.1.3) from Haloferax mediterranei (see paper)
    44% identity, 77% coverage of query (417 bits)

2OCS_HYDTT / D3DJ42 2-oxoglutarate carboxylase small subunit; 2-oxoglutarate carboxylase beta subunit; EC 6.4.1.7 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see 2 papers)
    44% identity, 71% coverage of query (394 bits)

3tw6B / Q2K340 Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a (see paper)
    42% identity, 70% coverage of query (380 bits)

3tw6C Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a
    40% identity, 70% coverage of query (353 bits)

3tw6A Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a
    36% identity, 70% coverage of query (292 bits)

8jxnJ / Q96RQ3 Human 3-methylcrotonyl-coa carboxylase in bccp-h1 state with mcoa
    36% identity, 72% coverage of query (292 bits)

2qf7A / Q2K340 Crystal structure of a complete multifunctional pyruvate carboxylase from rhizobium etli (see paper)
    34% identity, 70% coverage of query (269 bits)

Build an alignment

Build an alignment for WP_026595791.1 and 31 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

ACAC_SCHPO / P78820 Acetyl-CoA carboxylase; ACC; Cell untimely torn protein 6; EC 6.4.1.2; EC 6.3.4.14 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
cut6 / RF|NP_593271.1 acetyl-CoA/biotin carboxylase; EC 6.3.4.14 from Schizosaccharomyces pombe (see 2 papers)
    27% identity, 98% coverage of query (234 bits)

ACAC_YEAST / Q00955 Acetyl-CoA carboxylase; ACC; Fatty acid synthetase 3; mRNA transport-defective protein 7; EC 6.4.1.2; EC 6.3.4.14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
Q00955 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (EC 6.4.1.2) from Saccharomyces cerevisiae (see 6 papers)
    26% identity, 99% coverage of query (213 bits)

5cslB / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
    28% identity, 71% coverage of query (202 bits)

5cslA / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
    25% identity, 100% coverage of query (197 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory