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Searching for up to 100 curated homologs for WP_026596459.1 NCBI__GCF_000421465.1:WP_026596459.1 (801 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

otsB1 / P9WN15 trehalose-6-phosphate phosphatase OtsB1 (EC 3.1.3.12) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
Y2006_MYCTO / P9WN14 Uncharacterized glycosyl hydrolase MT2062; EC 3.2.1.- from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see paper)
Y2006_MYCTU / P9WN15 Uncharacterized glycosyl hydrolase Rv2006; EC 3.2.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
    51% identity, 99% coverage of query (784 bits)

trePP / Q9CID5 trehalose-6-phosphate phosphorylase (EC 2.4.1.216) from Lactococcus lactis subsp. lactis (strain IL1403) (see paper)
Q9CID5 trehalose 6-phosphate phosphorylase (EC 2.4.1.216) from Lactococcus lactis (see paper)
AAK04526.1 trehalose-6-phosphate phosphorylase (TrePP;YeeA;L39593;LL0428) (EC 2.4.1.216) (see protein)
    33% identity, 98% coverage of query (423 bits)

A4XGP2 kojibiose phosphorylase (EC 2.4.1.230) from Caldicellulosiruptor saccharolyticus (see paper)
ABP66077.1 kojibiose phosphorylase (CsKP;Csac_0439) (EC 2.4.1.230) (see protein)
3wirA / A4XGP2 Crystal structure of kojibiose phosphorylase complexed with glucose (see paper)
    32% identity, 94% coverage of query (362 bits)

3wiqA Crystal structure of kojibiose phosphorylase complexed with kojibiose
    32% identity, 94% coverage of query (362 bits)

kojP / Q8L163 kojibiose phosphorylase monomer (EC 2.4.1.230) from Thermoanaerobacter brockii (see 7 papers)
Q8L163 kojibiose phosphorylase (EC 2.4.1.230) from Thermoanaerobacter brockii (see paper)
AAE30762.1 kojibiose phosphorylase (KojP;KPase) (EC 2.4.1.230) (see protein)
    31% identity, 96% coverage of query (345 bits)

Build an alignment

Build an alignment for WP_026596459.1 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

TREP_THEBR / Q8L164 Alpha,alpha-trehalose phosphorylase; TPase; EC 2.4.1.64 from Thermoanaerobacter brockii (Thermoanaerobium brockii)
Q8L164 alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) from Thermoanaerobacter brockii (see paper)
BAB97299.1 trehalose phosphorylase (TreP) (EC 2.4.1.64) (see protein)
    27% identity, 97% coverage of query (268 bits)

CA265_RS24655 maltose phosphorylase (EC 2.4.1.8) from Pedobacter sp. GW460-11-11-14-LB5
    25% identity, 98% coverage of query (254 bits)

GGP_BACIE / D6XZ22 1,2-alpha-glucosylglycerol phosphorylase; 2-O-alpha-glucosylglycerol phosphorylase; GGP; EC 2.4.1.332 from Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) (see 2 papers)
D6XZ22 1,2-alpha-glucosylglycerol phosphorylase (EC 2.4.1.332) from Salisediminibacterium selenitireducens (see 2 papers)
ADI00307.1 2-O-α-glucopyranosylglycerol: phosphate β-glucosyltransferase / 2-O-α-glucosylglycerol phosphorylase (GGP;Bsel_2816) (EC 2.4.1.-) (see protein)
    28% identity, 98% coverage of query (253 bits)

4ktpA / D6XZ22 Crystal structure of 2-o-alpha-glucosylglycerol phosphorylase in complex with glucose (see paper)
    28% identity, 98% coverage of query (252 bits)

4ktpB Crystal structure of 2-o-alpha-glucosylglycerol phosphorylase in complex with glucose
    28% identity, 98% coverage of query (252 bits)

4ktrA Crystal structure of 2-o-alpha-glucosylglycerol phosphorylase in complex with isofagomine and glycerol
    28% identity, 98% coverage of query (252 bits)

treP / Q8GRC3 trehalose phosphorylase subunit (EC 2.4.1.64) from Geobacillus stearothermophilus (see 2 papers)
TREP_GEOSE / Q8GRC3 Alpha,alpha-trehalose phosphorylase; TPase; EC 2.4.1.64 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see paper)
BAC20640.1 trehalose phosphorylase (TPase) (EC 2.4.1.64) (see protein)
    27% identity, 95% coverage of query (245 bits)

Cphy_1019 / A9KM56 3-O-α-D-glucosyl-L-rhamnose phosphorylase (EC 2.4.1.282) from Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (see paper)
3OAGR_LACP7 / A9KM56 3-O-alpha-D-glucosyl-L-rhamnose phosphorylase; 3-O-alpha-D-glucopyranosyl-L-rhamnopyranose:phosphate beta-D-glucosyltransferase; EC 2.4.1.282 from Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Clostridium phytofermentans) (see paper)
A9KM56 3-O-alpha-D-glucosyl-L-rhamnose phosphorylase (EC 2.4.1.282) from Lachnoclostridium phytofermentans (see paper)
ABX41399.1 3-O-α-glucopyranosyl-L-rhamnose phosphorylase (Cphy_1019) (EC 2.4.1.282) (see protein)
    26% identity, 96% coverage of query (233 bits)

BAD97810.1 maltose phosphorylase (MapA) (EC 2.4.1.8) (see protein)
    27% identity, 95% coverage of query (232 bits)

D6XSD4 alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) from Salisediminibacterium selenitireducens (see paper)
    28% identity, 95% coverage of query (232 bits)

NIGP_LACP7 / A9KT32 Nigerose phosphorylase; EC 2.4.1.279 from Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Clostridium phytofermentans) (see paper)
A9KT32 nigerose phosphorylase (EC 2.4.1.279) from Lachnoclostridium phytofermentans (see paper)
ABX42243.1 nigerose phosphorylase (Cphy_1874) (EC 2.4.1.279) (see protein)
    26% identity, 93% coverage of query (223 bits)

YcjT / b1316 kojibiose phosphorylase (EC 2.4.1.230) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ycjT / P77154 kojibiose phosphorylase (EC 2.4.1.230) from Escherichia coli (strain K12) (see 2 papers)
KOJP_ECOLI / P77154 Kojibiose phosphorylase; EC 2.4.1.230 from Escherichia coli (strain K12) (see paper)
P77154 kojibiose phosphorylase (EC 2.4.1.230) from Escherichia coli (see paper)
    26% identity, 96% coverage of query (219 bits)

D6XUS4 maltose phosphorylase (EC 2.4.1.8) from Salisediminibacterium selenitireducens (see paper)
ADH99560.1 maltose phosphorylase (Bsel2056;Bsel_2056) (EC 2.4.1.8) (see protein)
    26% identity, 96% coverage of query (214 bits)

Q7SIE1 maltose phosphorylase (EC 2.4.1.8) from Levilactobacillus brevis (see 2 papers)
1h54B / Q7SIE1 Maltose phosphorylase from lactobacillus brevis (see paper)
    24% identity, 96% coverage of query (200 bits)

Q5FI04 maltose phosphorylase (EC 2.4.1.8) from Lactobacillus acidophilus (see 2 papers)
AAV43670.1 maltose phosphorylase (MalP;LBA1870) (EC 2.4.1.8) (see protein)
    25% identity, 95% coverage of query (198 bits)

BAC54904.1 maltose phosphorylase (MPase) (EC 2.4.1.8) (see protein)
    27% identity, 94% coverage of query (196 bits)

MALPY_ENTFT / E6ENP7 Maltose phosphorylase; EC 2.4.1.8 from Enterococcus faecalis (strain TX4000 / JH2-2) (see paper)
    25% identity, 94% coverage of query (187 bits)

AAO80764.1 maltose phosphorylase (MalP;EF0957) (EC 2.4.1.8) (see protein)
    25% identity, 94% coverage of query (186 bits)

CAA11905.1 maltose phosphorylase (EC 2.4.1.8) (see protein)
    26% identity, 95% coverage of query (182 bits)

CCE43253.1 trehalase (Atc1;CpATC1;CPAR2_208980) (EC 3.2.1.28) (see protein)
    22% identity, 94% coverage of query (95.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory