Searching for up to 100 curated homologs for WP_027179882.1 NCBI__GCF_000429985.1:WP_027179882.1 (491 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YiaX / b3588 aldehyde dehydrogenase B (EC 1.2.1.4) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
aldB / P37685 aldehyde dehydrogenase B (EC 1.2.1.4) from Escherichia coli (strain K12) (see 7 papers)
ALDB_ECOLI / P37685 Aldehyde dehydrogenase B; Acetaldehyde dehydrogenase; EC 1.2.1.4 from Escherichia coli (strain K12) (see 2 papers)
aldB / GB|AAC76612.2 aldehyde dehydrogenase B; EC 1.2.1.- from Escherichia coli K12 (see 5 papers)
aldB / AAC36939.1 aldehyde dehydrogenase B from Escherichia coli (see paper)
48% identity, 98% coverage of query (493 bits)
Psest_2276 Aldehyde dehydrogenase (EC 1.2.1.3) from Pseudomonas stutzeri RCH2
49% identity, 98% coverage of query (481 bits)
Q8KZT4 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Cytophaga sp. (see paper)
48% identity, 100% coverage of query (478 bits)
HP15_3144 Aldehyde dehydrogenase (EC 1.2.1.3) from Marinobacter adhaerens HP15
47% identity, 98% coverage of query (477 bits)
pedI / B1N7J6 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Pseudomonas putida (see paper)
48% identity, 98% coverage of query (477 bits)
adh / A1B4L2 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Paracoccus denitrificans (strain Pd 1222) (see paper)
ALDH_PARDP / A1B4L2 Aldehyde dehydrogenase; Acetaldehyde dehydrogenase; EC 1.2.1.3 from Paracoccus denitrificans (strain Pd 1222) (see paper)
47% identity, 99% coverage of query (474 bits)
BWI76_RS21985 acetaldehyde dehydrogenase (EC 1.2.1.3) from Klebsiella michiganensis M5al
46% identity, 99% coverage of query (468 bits)
aldB / AAC13644.1 NAD-dependent chloroacetaldehyde dehydrogenase from Xanthobacter autotrophicus (see paper)
48% identity, 100% coverage of query (468 bits)
ALD1_ACISP / Q9FDS1 Long-chain-aldehyde dehydrogenase; Aldehyde dehydrogenase 1; EC 1.2.1.48 from Acinetobacter sp. (see paper)
46% identity, 99% coverage of query (467 bits)
ACLDH_PSEAI / Q9ZAA1 Acetaldehyde dehydrogenase; EC 1.2.1.- from Pseudomonas aeruginosa (see paper)
48% identity, 98% coverage of query (465 bits)
aldA / AAC13641.1 chloroacetaldehyde dehydrogenase from Xanthobacter autotrophicus (see paper)
46% identity, 100% coverage of query (459 bits)
Q4F895 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Rhodococcus erythropolis (see paper)
47% identity, 98% coverage of query (457 bits)
thcA / AAC77472.1 ThcA from Rhodococcus erythropolis (see 3 papers)
47% identity, 98% coverage of query (453 bits)
adh3 / Q768S6 NAD+-dependent secondary alcohol dehydrogenase III monomer from Gordonia sp. (strain TY-5) (see paper)
45% identity, 99% coverage of query (448 bits)
FLUDE_STREN / F8JX40 Fluoroacetaldehyde dehydrogenase; EC 1.2.1.69 from Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) (Streptomyces cattleya) (see paper)
46% identity, 98% coverage of query (446 bits)
ALDH4_BACSU / O34660 Putative aldehyde dehydrogenase DhaS; EC 1.2.1.3 from Bacillus subtilis (strain 168) (see paper)
46% identity, 97% coverage of query (443 bits)
ald / Q8NLZ0 acetaldehyde dehydrogenase (EC 1.2.1.3; EC 1.2.1.46) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
45% identity, 99% coverage of query (437 bits)
Q402C7 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Sphingomonas sp. (see paper)
phnN / BAE19973.1 aldehyde dehydrogenase from Sphingomonas sp. 14DN-61 (see paper)
43% identity, 99% coverage of query (417 bits)
8rwkA / P46367 Cryoem structure of the central ald4 filament determined by filamentid (see paper)
45% identity, 98% coverage of query (412 bits)
ALD4 / P46367 potassium-activated aldehyde dehydrogenase, mitochondrial (EC 1.2.1.4; EC 1.2.1.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
ALDH4_YEAST / P46367 Potassium-activated aldehyde dehydrogenase, mitochondrial; K(+)-activated acetaldehyde dehydrogenase; K(+)-ACDH; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P46367 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Saccharomyces cerevisiae (see paper)
45% identity, 98% coverage of query (412 bits)
ALD5 / P40047 aldehyde dehydrogenase, mitochondrial (EC 1.2.1.4; EC 1.2.1.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
ALDH5_YEAST / P40047 Aldehyde dehydrogenase 5, mitochondrial; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
43% identity, 98% coverage of query (410 bits)
ALDH1A2 / O94788 retinal dehydrogenase 2 (EC 1.2.1.36) from Homo sapiens (see 4 papers)
AL1A2_HUMAN / O94788 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); EC 1.2.1.36 from Homo sapiens (Human) (see 3 papers)
O94788 retinal dehydrogenase (EC 1.2.1.36) from Homo sapiens (see 6 papers)
44% identity, 97% coverage of query (409 bits)
6aljA / O94788 Aldh1a2 liganded with NAD and compound win18,446 (see paper)
44% identity, 97% coverage of query (409 bits)
6b5hA Aldh1a2 liganded with NAD and 1-(4-cyanophenyl)-n-(3-fluorophenyl)-3- [4-(methylsulfonyl)phenyl]-1h-pyrazole-4-carboxamide (compound cm121)
44% identity, 97% coverage of query (409 bits)
6b5gA Aldh1a2 liganded with NAD and (3-ethoxythiophen-2-yl){4-[4-nitro-3- (pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone (compound 6-118)
44% identity, 97% coverage of query (409 bits)
5gtkA NAD+ complex structure of aldehyde dehydrogenase from bacillus cereus
42% identity, 98% coverage of query (404 bits)
AL1A2_MOUSE / Q62148 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); EC 1.2.1.36 from Mus musculus (Mouse) (see 3 papers)
Q62148 retinal dehydrogenase (EC 1.2.1.36) from Mus musculus (see 6 papers)
45% identity, 97% coverage of query (404 bits)
P47738 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see 4 papers)
43% identity, 97% coverage of query (404 bits)
5gtlA NADPH complex structure of aldehyde dehydrogenase from bacillus cereus
42% identity, 98% coverage of query (404 bits)
AL1A2_RAT / Q63639 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); EC 1.2.1.36 from Rattus norvegicus (Rat) (see paper)
Q63639 retinal dehydrogenase (EC 1.2.1.36) from Rattus norvegicus (see 4 papers)
44% identity, 97% coverage of query (403 bits)
O93344 retinal dehydrogenase (EC 1.2.1.36) from Gallus gallus (see paper)
44% identity, 97% coverage of query (403 bits)
Q9CZS1 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see 2 papers)
43% identity, 99% coverage of query (402 bits)
P30837 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see 2 papers)
42% identity, 99% coverage of query (400 bits)
7mjcA / P30837 Crystal structure analysis of aldh1b1
42% identity, 99% coverage of query (400 bits)
7radA Crystal structure analysis of aldh1b1
42% identity, 99% coverage of query (400 bits)
7mjdA Crystal structure analysis of aldh1b1
42% identity, 99% coverage of query (400 bits)
P11884 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Rattus norvegicus (see 4 papers)
42% identity, 99% coverage of query (399 bits)
aldA / RF|XP_658158.1 aldehyde dehydrogenase ALDH; EC 1.2.1.3 from Emericella nidulans (see 5 papers)
44% identity, 98% coverage of query (398 bits)
LADH / A3LNE3 NAD(P)+ L-lactaldehyde dehydrogenase from Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (see paper)
43% identity, 98% coverage of query (396 bits)
4o6rA / B4EJX1 Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
39% identity, 97% coverage of query (396 bits)
Q8K4D8 retinal dehydrogenase (EC 1.2.1.36) from Rattus norvegicus (see paper)
42% identity, 97% coverage of query (395 bits)
ALDH2 / P05091 mitochondrial aldehyde dehydrogenase subunit (EC 1.2.1.3; EC 1.2.1.39) from Homo sapiens (see 14 papers)
ALDH2_HUMAN / P05091 Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI; EC 1.2.1.3 from Homo sapiens (Human) (see 3 papers)
P05091 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see 13 papers)
42% identity, 99% coverage of query (394 bits)
O14293 Putative aldehyde dehydrogenase-like protein C9E9.09c; EC 1.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
43% identity, 97% coverage of query (394 bits)
AL1A3_MOUSE / Q9JHW9 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; Aldh1a3; EC 1.2.1.36 from Mus musculus (Mouse) (see 7 papers)
Q9JHW9 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Mus musculus (see 4 papers)
42% identity, 97% coverage of query (393 bits)
AL1A2_TAEGU / Q9I8W8 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); zRalDH; EC 1.2.1.36 from Taeniopygia guttata (Zebra finch) (Poephila guttata) (see paper)
44% identity, 97% coverage of query (393 bits)
P20000 Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI; EC 1.2.1.3 from Bos taurus (Bovine)
42% identity, 99% coverage of query (393 bits)
5l13A Structure of aldh2 in complex with 2p3
42% identity, 99% coverage of query (393 bits)
4kwgA Crystal structure analysis of aldh2+aldib13
42% identity, 99% coverage of query (393 bits)
4kwfA Crystal structure analysis of aldh2+aldib33
42% identity, 99% coverage of query (393 bits)
3sz9A Crystal structure of human aldh2 modified with the beta-elimination product of aldi-3; 1-(4-ethylbenzene)prop-2-en-1-one
42% identity, 99% coverage of query (393 bits)
3injA Human mitochondrial aldehyde dehydrogenase complexed with agonist alda-1
42% identity, 99% coverage of query (393 bits)
2vleA The structure of daidzin, a naturally occurring anti alcohol- addiction agent, in complex with human mitochondrial aldehyde dehydrogenase
42% identity, 99% coverage of query (393 bits)
1o01B Human mitochondrial aldehyde dehydrogenase complexed with crotonaldehyde, NAD(h) and mg2+
42% identity, 99% coverage of query (393 bits)
1cw3A Human mitochondrial aldehyde dehydrogenase complexed with NAD+ and mn2+
42% identity, 99% coverage of query (393 bits)
Q9FRX7 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Oryza sativa (see paper)
43% identity, 97% coverage of query (391 bits)
ALDH_DAVTA / P40108 Aldehyde dehydrogenase; ALDDH; ALDH; Allergen Cla h 3; Allergen Cla h III; Allergen Cla h 10; EC 1.2.1.3 from Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum) (see paper)
43% identity, 99% coverage of query (390 bits)
4cazA / Q9HTJ1 Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
39% identity, 97% coverage of query (390 bits)
BETB_PSEAE / Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HTJ1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Pseudomonas aeruginosa (see 5 papers)
39% identity, 97% coverage of query (390 bits)
2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct.
39% identity, 97% coverage of query (390 bits)
2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa
39% identity, 97% coverage of query (390 bits)
1nzwA Cys302ser mutant of human mitochondrial aldehyde dehydrogenase complexed with nadh and mg2+
42% identity, 99% coverage of query (390 bits)
Q0H2G3 retinal dehydrogenase (EC 1.2.1.36) from Danio rerio (see paper)
42% identity, 97% coverage of query (388 bits)
4fr8C / P05091 Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin (see paper)
42% identity, 99% coverage of query (388 bits)
4fr8A Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin
42% identity, 99% coverage of query (388 bits)
2onmA Human mitochondrial aldehyde dehydrogenase asian variant, aldh2 2, Complexed with NAD+
43% identity, 96% coverage of query (386 bits)
ALDH1A3 / P47895 retinal dehydrogenase 3 (EC 1.2.1.36) from Homo sapiens (see 3 papers)
AL1A3_HUMAN / P47895 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; ALDH1A3; EC 1.2.1.36 from Homo sapiens (Human) (see 9 papers)
P47895 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Homo sapiens (see 6 papers)
42% identity, 97% coverage of query (385 bits)
7a6qB Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound
42% identity, 97% coverage of query (384 bits)
7a6qA / P47895 Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound (see paper)
42% identity, 97% coverage of query (384 bits)
5fhzA Human aldehyde dehydrogenase 1a3 complexed with NAD(+) and retinoic acid
42% identity, 97% coverage of query (384 bits)
7qk9A Crystal structure of the aldh1a3-atp complex
42% identity, 97% coverage of query (383 bits)
6tgwA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with a selective inhibitor
42% identity, 97% coverage of query (380 bits)
6te5B Crystal structure of human aldehyde dehydrogenase 1a3 in complex with lq43 inhibitor compound
41% identity, 97% coverage of query (379 bits)
6tryA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with mf13 inhibitor compound
41% identity, 97% coverage of query (379 bits)
AL2C4_ARATH / Q56YU0 Aldehyde dehydrogenase family 2 member C4; ALDH1a; Protein REDUCED EPIDERMAL FLUORESCENCE 1; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
42% identity, 98% coverage of query (374 bits)
ALD6 / P54115 magnesium-activated aldehyde dehydrogenase, cytosolic (EC 1.2.1.4) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
ALDH6_YEAST / P54115 Magnesium-activated aldehyde dehydrogenase, cytosolic; Mg(2+)-activated acetaldehyde dehydrogenase; Mg(2+)-ACDH; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P54115 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Saccharomyces cerevisiae (see 2 papers)
41% identity, 97% coverage of query (369 bits)
ALDH1A1 / P00352 retinal dehydrogenase 1 (EC 1.2.1.36) from Homo sapiens (see 10 papers)
AL1A1_HUMAN / P00352 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Homo sapiens (Human) (see 7 papers)
P00352 retinal dehydrogenase (EC 1.2.1.36) from Homo sapiens (see 6 papers)
41% identity, 98% coverage of query (367 bits)
5teiA Structure of human aldh1a1 with inhibitor cm039
41% identity, 98% coverage of query (367 bits)
4x4lA Structure of human aldh1a1 with inhibitor cm037
41% identity, 98% coverage of query (367 bits)
4wb9A Human aldh1a1 complexed with nadh
41% identity, 98% coverage of query (367 bits)
8t0nA Structure of compound 4 bound to human aldh1a1
41% identity, 98% coverage of query (367 bits)
7jwwA Crystal structure of human aldh1a1 bound to compound (r)-28
41% identity, 98% coverage of query (367 bits)
7jwvA Crystal structure of human aldh1a1 bound to compound (r)-28
41% identity, 98% coverage of query (367 bits)
7jwuA Crystal structure of human aldh1a1 bound to compound (r)-28
41% identity, 98% coverage of query (367 bits)
7jwtA Crystal structure of human aldh1a1 bound to compound (r)-28
41% identity, 98% coverage of query (367 bits)
7jwsA Crystal structure of human aldh1a1 bound to compound (r)-28
41% identity, 98% coverage of query (367 bits)
6dumA Aldh1a1 n121s in complex with 6-{[(3-fluorophenyl)methyl]sulfanyl}-2- (oxetan-3-yl)-5-phenyl-2,5-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-one (compound 13g)
41% identity, 98% coverage of query (367 bits)
4wp7A Structure of human aldh1a1 with inhibitor cm026
41% identity, 98% coverage of query (367 bits)
8t0tA Structure of compound 4 bound to human aldh1a1
41% identity, 98% coverage of query (367 bits)
7um9A Human aldh1a1 with bound compound cm38
41% identity, 98% coverage of query (367 bits)
6s6wA Crystal structure of human aldh1a3 in complex with 2,6- diphenylimidazo[1,2-a]pyridine (compound ga11) and NAD+
41% identity, 97% coverage of query (367 bits)
5l2oA Crystal structure of aldh1a1 in complex with buc22
41% identity, 98% coverage of query (367 bits)
5l2nA Structure of aldh1a1 in complex with buc25
41% identity, 98% coverage of query (367 bits)
5l2mA Structure of aldh1a1 in complex with buc11
41% identity, 98% coverage of query (367 bits)
4wpnA Structure of human aldh1a1 with inhibitor cm053
41% identity, 98% coverage of query (367 bits)
AL1A1_SHEEP / P51977 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Ovis aries (Sheep) (see 2 papers)
40% identity, 97% coverage of query (361 bits)
4go4A / C1I208 Crystal structure of pnpe in complex with nicotinamide adenine dinucleotide
38% identity, 99% coverage of query (361 bits)
5ac0A Ovis aries aldehyde dehydrogenase 1a1 in complex with a duocarmycin analog
40% identity, 97% coverage of query (360 bits)
5abmA / P51977 Sheep aldehyde dehydrogenase 1a1 (see paper)
40% identity, 97% coverage of query (360 bits)
1bxsA Sheep liver class 1 aldehyde dehydrogenase with NAD bound
40% identity, 97% coverage of query (360 bits)
1o9jA / Q28399 The x-ray crystal structure of eta-crystallin (see paper)
41% identity, 98% coverage of query (359 bits)
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