Searching for up to 100 curated homologs for WP_027180538.1 NCBI__GCF_000429985.1:WP_027180538.1 (166 a.a.)
Found high-coverage hits (≥70%) to 23 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DVU2983 3-isopropylmalate dehydratase / (R)-citramalate isomerase, small subunit LeuD (EC 4.2.1.33; EC 4.2.1.35) from Desulfovibrio vulgaris Hildenborough JW710
73% identity, 100% coverage of query (259 bits)
leuD / Q58673 isopropylmalate isomerase small subunit (EC 4.2.1.35) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
LEUD_METJA / Q58673 Isopropylmalate/citramalate isomerase small subunit; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; EC 4.2.1.33; EC 4.2.1.35; EC 4.2.1.31 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q58673 3-isopropylmalate dehydratase (EC 4.2.1.33) from Methanocaldococcus jannaschii (see paper)
56% identity, 98% coverage of query (184 bits)
dmdB / Q0QLE1 dimethylmaleate hydratase subunit B (EC 4.2.1.85) from Eubacterium barkeri (see paper)
DMDB_EUBBA / Q0QLE1 2,3-dimethylmalate dehydratase small subunit; EC 4.2.1.85 from Eubacterium barkeri (Clostridium barkeri) (see 2 papers)
53% identity, 95% coverage of query (176 bits)
hacB / Q58667 homoaconitase β subunit (EC 4.2.1.36) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
HACB_METJA / Q58667 Methanogen homoaconitase small subunit; HACN; Homoaconitate hydratase; EC 4.2.1.114 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 3 papers)
53% identity, 97% coverage of query (163 bits)
2pkpA / Q58667 Crystal structure of 3-isopropylmalate dehydratase (leud)from methhanocaldococcus jannaschii dsm2661 (mj1271) (see paper)
53% identity, 97% coverage of query (163 bits)
O59393 3-isopropylmalate dehydratase (EC 4.2.1.33) from Pyrococcus horikoshii (see paper)
38% identity, 97% coverage of query (112 bits)
lysU / Q9ZND9 homoaconitase small subunit (EC 4.2.1.36) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 3 papers)
HACB_THET2 / Q9ZND9 Homoaconitase small subunit; HACN; Homoaconitate hydratase; EC 4.2.1.36 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
40% identity, 93% coverage of query (103 bits)
lysF / GI|1628374 homoaconitase, mitochondrial; EC 4.2.1.36 from Emericella nidulans (see paper)
36% identity, 89% coverage of query (90.1 bits)
LYS4_EMENI / Q92412 Homoaconitase, mitochondrial; Homoaconitate hydratase; EC 4.2.1.36 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
Q92412 homoaconitate hydratase (EC 4.2.1.36) from Aspergillus nidulans (see paper)
36% identity, 89% coverage of query (90.1 bits)
IIL1 / Q9ZW85 isopropylmalate isomerase, small subunit (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
LEUD3_ARATH / Q9ZW85 3-isopropylmalate dehydratase small subunit 1; AtLEUD3; Isopropylmalate isomerase small subunit 1; IPMI SSU1; EC 4.2.1.33 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9ZW85 2-(omega-methylthio)alkylmalate dehydratase (subunit 1/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
37% identity, 96% coverage of query (86.3 bits)
lys2 / RF|NP_593437.1 homoaconitate hydratase Lys2; EC 4.2.1.36 from Schizosaccharomyces pombe (see 2 papers)
33% identity, 93% coverage of query (85.5 bits)
ACON3_ASPFU / Q4WBR0 Putative aconitate hydratase; Aconitase 3; EC 4.2.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
38% identity, 72% coverage of query (83.2 bits)
B1P2N4 homoaconitate hydratase (EC 4.2.1.36) from Penicillium chrysogenum (see paper)
34% identity, 92% coverage of query (82.4 bits)
LYS4_ASPFU / Q4WUL6 Homoaconitase, mitochondrial; Homoaconitate hydratase; EC 4.2.1.36 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
32% identity, 92% coverage of query (80.5 bits)
AN5886 alpha isopropylmalate isomerase (Eurofung) from Emericella nidulans (see paper)
37% identity, 85% coverage of query (79.7 bits)
AMT8_ALTAL / C9K7B9 Aconitase AMT8; AM-toxin biosynthesis protein 8; EC 4.2.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
37% identity, 73% coverage of query (79.0 bits)
IPMI2 / Q9ZW84 isopropylmalate isomerase, small subunit (EC 4.2.1.170) from Arabidopsis thaliana (see paper)
LEUD1_ARATH / Q9ZW84 3-isopropylmalate dehydratase small subunit 2; 2-(omega-methylthio)alkylmalate dehydratase small subunit 2; AtLEUD1; Isopropylmalate isomerase 2; Isopropylmalate isomerase small subunit 2; IPMI SSU2; Methylthioalkylmalate isomerase small subunit; MAM-IS; EC 4.2.1.33; EC 4.2.1.170 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9ZW84 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
33% identity, 95% coverage of query (78.6 bits)
LeuD / b0071 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
leuD / P30126 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli (strain K12) (see 4 papers)
33% identity, 86% coverage of query (78.2 bits)
LEUD1_SALTY / P04787 3-isopropylmalate dehydratase small subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
36% identity, 71% coverage of query (75.5 bits)
AMT82_ALTAL / C9K7I3 Aconitase AMT8-2; AM-toxin biosynthesis protein 8-2; EC 4.2.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
36% identity, 73% coverage of query (73.6 bits)
O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
32% identity, 85% coverage of query (71.6 bits)
Build an alignment for WP_027180538.1 and 21 homologs with ≥ 30% identity
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LEUD_CORGL / Q8NQV7 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
28% identity, 85% coverage of query (56.2 bits)
ACO3M_ARATH / Q9SIB9 Aconitate hydratase 3, mitochondrial; Aconitase 3; mACO1; Citrate hydro-lyase 3; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9SIB9 aconitate hydratase (EC 4.2.1.3) from Arabidopsis thaliana (see paper)
30% identity, 72% coverage of query (42.7 bits)
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Lawrence Berkeley National Laboratory