Searching for up to 100 curated homologs for WP_028313202.1 NCBI__GCF_000429905.1:WP_028313202.1 (339 a.a.)

Found high-coverage hits (≥70%) to 33 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q9WYH8 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Thermotoga maritima (see paper)
3pg9A / Q9WYH8 Thermotoga maritima dah7p synthase in complex with inhibitor (see paper)
    49% identity, 98% coverage of query (328 bits)

1rzmA Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahps) from thermotoga maritima complexed with cd2+, pep and e4p
    49% identity, 98% coverage of query (328 bits)

4grsA / Q8U0A9,Q9WYH8 Crystal structure of a chimeric dah7ps (see paper)
    49% identity, 96% coverage of query (325 bits)

5j6fA / L8A208 Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
    45% identity, 91% coverage of query (286 bits)

3nvtA / Q8Y6T2 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
    51% identity, 76% coverage of query (281 bits)

3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate
    51% identity, 76% coverage of query (281 bits)

1zcoB Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    53% identity, 73% coverage of query (273 bits)

1zcoA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    53% identity, 73% coverage of query (273 bits)

4c1kA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    53% identity, 75% coverage of query (273 bits)

P39912 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54); chorismate mutase (EC 5.4.99.5) from Bacillus subtilis (see paper)
    50% identity, 76% coverage of query (268 bits)

P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168)
    50% identity, 76% coverage of query (268 bits)

ccmA / BAA05463.1 32.4kD protein from Synechocystis sp. PCC 6803 (see paper)
    46% identity, 86% coverage of query (266 bits)

1vs1D / Q9YEJ7 Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahp synthase) from aeropyrum pernix in complex with mn2+ and pep
    53% identity, 75% coverage of query (234 bits)

Q9YEJ7 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Aeropyrum pernix (see paper)
    53% identity, 75% coverage of query (234 bits)

A0A482F152 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from uncultured bacterium (see paper)
    48% identity, 71% coverage of query (215 bits)

P95514 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Mannheimia haemolytica (see paper)
    30% identity, 77% coverage of query (100 bits)

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Build an alignment for WP_028313202.1 and 16 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

O68662 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Actinobacillus pleuropneumoniae (see paper)
    29% identity, 77% coverage of query (99.8 bits)

P45251 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Haemophilus influenzae (see paper)
    27% identity, 77% coverage of query (97.1 bits)

Q8GLK7 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Aquifex pyrophilus (see paper)
    28% identity, 72% coverage of query (92.8 bits)

1g7uA / P0A715 Crystal structures of kdo8p synthase in its binary complex with substrate phosphoenol pyruvate (see paper)
    29% identity, 76% coverage of query (91.7 bits)

KdsA / b1215 3-deoxy-D-manno-octulosonate 8-phosphate synthase (EC 2.5.1.55) from Escherichia coli K-12 substr. MG1655 (see 24 papers)
kdsA / P0A715 3-deoxy-D-manno-octulosonate 8-phosphate synthase (EC 2.5.1.55) from Escherichia coli (strain K12) (see 25 papers)
KDSA_ECOLI / P0A715 2-dehydro-3-deoxyphosphooctonate aldolase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase; EC 2.5.1.55 from Escherichia coli (strain K12) (see paper)
P0A715 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Escherichia coli (see 5 papers)
kdsA / PDB|1PHQ 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; EC 2.5.1.55 from Escherichia coli K12 (see 11 papers)
    29% identity, 76% coverage of query (91.3 bits)

Q9ZN55 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Helicobacter pylori (see paper)
    27% identity, 71% coverage of query (91.3 bits)

1g7vA Crystal structures of kdo8p synthase in its binary complexes with the mechanism-based inhibitor
    29% identity, 76% coverage of query (91.3 bits)

1x6uA Kdo8p synthase in it's binary complex with the product kdo8p
    29% identity, 76% coverage of query (90.1 bits)

1phwA Crystal structure of kdo8p synthase in its binary complex with substrate analog 1-deoxy-a5p
    29% identity, 76% coverage of query (90.1 bits)

1phqA Crystal structure of kdo8p synthase in its binary complex with substrate analog e-fpep
    29% identity, 76% coverage of query (90.1 bits)

Q9JZ55 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Neisseria meningitidis serogroup B (see paper)
    26% identity, 75% coverage of query (89.7 bits)

1gg0A Crystal structure analysis of kdop synthase at 3.0 a
    29% identity, 76% coverage of query (89.0 bits)

4z1dA / P56060 Structure of pep and zinc bound kdo8ps from h.Pylori (see paper)
    28% identity, 71% coverage of query (87.4 bits)

P56060 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Helicobacter pylori (see paper)
    28% identity, 71% coverage of query (84.3 bits)

Q9ZFK4 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Pseudomonas aeruginosa (see paper)
    25% identity, 75% coverage of query (83.2 bits)

3fyoD / Q9JZ55 Crystal structure of the triple mutant (n23c/d247e/p249a) of 3-deoxy- d-manno-octulosonate 8-phosphate synthase (kdo8ps) from neisseria meningitidis (see paper)
    26% identity, 75% coverage of query (80.1 bits)

Q46225 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Chlamydia psittaci (see paper)
    29% identity, 71% coverage of query (70.1 bits)

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