Sites on a Tree

 

Searching for up to 100 curated homologs for WP_028314132.1 NCBI__GCF_000429905.1:WP_028314132.1 (204 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q5NMD4 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Zymomonas mobilis (see paper)
    47% identity, 100% coverage of query (192 bits)

HSERO_RS20325 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Herbaspirillum seropedicae SmR1
    43% identity, 99% coverage of query (174 bits)

At-HF / Q9SZ30 imidazole-glycerol-phosphate synthase (EC 4.3.2.10) from Arabidopsis thaliana (see paper)
Q9SZ30 imidazole glycerol-phosphate synthase (EC 4.3.2.10) from Arabidopsis thaliana (see paper)
    38% identity, 99% coverage of query (149 bits)

HIS5_MYCBO / P59957 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
    39% identity, 97% coverage of query (141 bits)

DVU0285 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Desulfovibrio vulgaris Hildenborough JW710
    38% identity, 98% coverage of query (134 bits)

HisH / b2023 imidazole glycerol phosphate synthase subunit HisH (EC 4.3.2.10) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
hisH / P60595 imidazole glycerol phosphate synthase subunit HisH (EC 4.3.2.10) from Escherichia coli (strain K12) (see 5 papers)
HIS5_ECOLI / P60595 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Escherichia coli (strain K12) (see paper)
hisH / RF|NP_416527 IGP synthase glutamine amidotransferase subunit; EC 2.4.2.- from Escherichia coli K12 (see 7 papers)
    40% identity, 97% coverage of query (125 bits)

DvMF_2305 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Desulfovibrio vulgaris Miyazaki F
    35% identity, 100% coverage of query (124 bits)

1ox4B / P33734 Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase (see paper)
    36% identity, 100% coverage of query (124 bits)

HIS5_YEAST / P33734 Imidazole glycerol phosphate synthase hisHF; IGP synthase; IGPS; ImGP synthase; EC 4.3.2.10; EC 3.5.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P33734 imidazole glycerol-phosphate synthase (EC 4.3.2.10) from Saccharomyces cerevisiae (see 4 papers)
    36% identity, 100% coverage of query (123 bits)

1ox5A Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase
    36% identity, 100% coverage of query (123 bits)

HIS5_THET8 / Q7SIC0 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
Q7SIC0 imidazole glycerol-phosphate synthase (subunit 2/2) (EC 4.3.2.10) from Thermus thermophilus (see paper)
    38% identity, 95% coverage of query (119 bits)

Q8ZY40 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Pyrobaculum aerophilum (see paper)
    35% identity, 99% coverage of query (110 bits)

A4WHA5 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Pyrobaculum arsenaticum (see paper)
    36% identity, 99% coverage of query (109 bits)

hisH / Q9X0C8 imidazole-glycerol-phosphate synthase glutamine amidotransferase subunit (EC 4.3.2.10) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
HIS5_THEMA / Q9X0C8 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; TmHisH; EC 4.3.2.10; EC 3.5.1.2 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9X0C8 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Thermotoga maritima (see 5 papers)
    33% identity, 98% coverage of query (108 bits)

7ac8B / Q9X0C8 Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex. (see paper)
    33% identity, 98% coverage of query (105 bits)

cmlB / F2RB79 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see 2 papers)
ADCS_STRVP / F2RB79 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoate synthase; EC 2.6.1.85 from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
    31% identity, 91% coverage of query (55.8 bits)

8hx8A / F2RB79 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae co-crystallized with chorismate (see paper)
    30% identity, 91% coverage of query (54.7 bits)

papA / BAD21140.1 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae (see paper)
    30% identity, 91% coverage of query (54.7 bits)

Build an alignment

Build an alignment for WP_028314132.1 and 18 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory