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Searching for up to 100 curated homologs for WP_028316322.1 NCBI__GCF_000429905.1:WP_028316322.1 (396 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DVU0549 proline/arginine ABC transporter, permease component from Desulfovibrio vulgaris Hildenborough JW710
    60% identity, 100% coverage of query (491 bits)

Pf6N2E2_2924 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, permease component 2 LivM from Pseudomonas fluorescens FW300-N2E2
    56% identity, 75% coverage of query (323 bits)

AZOBR_RS08240 L-proline and D-alanine ABC transporter, permease component 2 from Azospirillum brasilense Sp245
    49% identity, 85% coverage of query (320 bits)

TC 3.A.1.4.8 / P21628 High-affinity branched-chain amino acid transport system permease protein BraE, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    54% identity, 72% coverage of query (288 bits)

braE / CAB75550.1 integral membrane protein from Rhizobium leguminosarum bv. viciae (see 2 papers)
    50% identity, 75% coverage of query (284 bits)

LivM / b3456 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
LivM / P22729 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM (EC 7.4.2.2) from Escherichia coli (strain K12) (see 5 papers)
LIVM_ECOLI / P22729 High-affinity branched-chain amino acid transport system permease protein LivM; LIV-I protein M from Escherichia coli (strain K12) (see paper)
TC 3.A.1.4.1 / P22729 LivM aka B3456, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 5 papers)
    48% identity, 74% coverage of query (280 bits)

HSERO_RS00890 L-proline ABC transporter, permease component 2 from Herbaspirillum seropedicae SmR1
    41% identity, 73% coverage of query (235 bits)

TC 3.A.1.4.10 / Q8DQH9 ABC transporter membrane-spanning permease-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    36% identity, 70% coverage of query (155 bits)

TC 3.A.1.4.3 / Q8VM84 BraE aka Bra2E, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae) (see paper)
    33% identity, 75% coverage of query (145 bits)

Build an alignment

Build an alignment for WP_028316322.1 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.4.11 / Q6N8W1 Putative branched-chain amino acid transport system ATP-binding protein, component of The phenylpropeneoid uptake porter, CouPSTW from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
    29% identity, 71% coverage of query (114 bits)

TC 3.A.1.4.7 / Q92TN2 ABC transporter, permease, component of The protocatechuate (3,4-dihydroxybenzoate) uptake porter, PcaMNVWX from Rhizobium meliloti (strain 1021)
    27% identity, 74% coverage of query (90.5 bits)

TC 3.A.1.4.4 / Q9L3S4 UrtC, component of The high-affinity (<1 μM) urea porter (see paper)
    25% identity, 74% coverage of query (84.0 bits)

TC 3.A.1.2.13 / A6VKS9 RbsC, component of The probable autoinducer-2 (AI-2;, a furanosyl borate diester: 3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Shao et al., 2007) (50-70% identical to RbsABC of E. coli; TC# 3.A.1.2.1) from Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
    26% identity, 74% coverage of query (58.5 bits)

TC 3.A.1.2.16 / Q1M4Q8 Erythritol permease, component of ABC transporter, component of The erythritol uptake permease, EryEFG (Yost et al., 2006) (probably orthologous to 3.A.1.2.11) from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    25% identity, 80% coverage of query (56.6 bits)

TC 3.A.1.4.5 / Q8NRV9 UrtC, component of The high affinity urea/thiourea/hydroxyurea porter from Corynebacterium glutamicum (see paper)
    25% identity, 72% coverage of query (54.3 bits)

eryF / Q2YIY3 putative erythritol ABC transporter membrane protein from Brucella abortus (strain 2308) (see 3 papers)
    23% identity, 80% coverage of query (51.2 bits)

LivH / b3457 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
LivH / P0AEX7 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH (EC 7.4.2.2) from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.4.1 / P0AEX7 High-affinity branched-chain amino acid transport system permease protein LivH aka B3457, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 6 papers)
livH high-affinity branched-chain amino acid ABC transporter, permease protein LivH from Escherichia coli K12 (see 6 papers)
    23% identity, 71% coverage of query (47.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory