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Searching for up to 100 curated homologs for WP_028321208.1 NCBI__GCF_000422285.1:WP_028321208.1 (573 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ACSA_BACSU / P39062 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Bacillus subtilis (strain 168) (see 2 papers)
acsA / AAA68287.1 acetyl-CoA synthetase from Bacillus subtilis (see 2 papers)
    41% identity, 98% coverage of query (453 bits)

8rplB / A0A535FEC2 Amp-forming acetyl-coa synthetase from chloroflexota bacterium with bound acetyl amp (see paper)
    35% identity, 92% coverage of query (322 bits)

Q2XNL6 acetate-CoA ligase (EC 6.2.1.1) from Methanothermobacter thermautotrophicus (see paper)
    33% identity, 93% coverage of query (304 bits)

Q2I0L7 acetate-CoA ligase (EC 6.2.1.1) from Methanothermobacter thermautotrophicus (see paper)
    32% identity, 93% coverage of query (296 bits)

ACSA_METTP / A0B8F1 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanosaeta thermophila) (see paper)
A0B8F1 acetate-CoA ligase (EC 6.2.1.1) from Methanothrix thermoacetophila (see paper)
    31% identity, 93% coverage of query (280 bits)

A4YGF9 4-hydroxybutyrate-CoA ligase (AMP-forming) (EC 6.2.1.40) from Metallosphaera sedula (see paper)
    32% identity, 93% coverage of query (278 bits)

ACSA_MYCS2 / A0R5G1 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    34% identity, 93% coverage of query (276 bits)

2p20A / Q8ZKF6 Acetyl-coa synthetase, r584a mutation (see paper)
    31% identity, 93% coverage of query (273 bits)

ACSA_SALTY / Q8ZKF6 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 5 papers)
    31% identity, 93% coverage of query (271 bits)

AcsA / b4069 acetyl-CoA synthetase (AMP-forming) (EC 6.2.1.1; EC 6.2.1.17) from Escherichia coli K-12 substr. MG1655 (see 48 papers)
acs / P27550 acetyl-CoA synthetase (AMP-forming) (EC 6.2.1.17; EC 6.2.1.1) from Escherichia coli (strain K12) (see 46 papers)
ACSA_ECOLI / P27550 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Escherichia coli (strain K12) (see 3 papers)
    31% identity, 93% coverage of query (271 bits)

5jrhA Crystal structure of salmonella enterica acetyl-coa synthetase (acs) in complex with camp and coenzyme a
    31% identity, 93% coverage of query (271 bits)

ACSA_MYCTU / P9WQD1 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
    32% identity, 93% coverage of query (270 bits)

2p2fA Acetyl-coa synthetase, wild-type with acetate, amp, and coa bound
    31% identity, 92% coverage of query (269 bits)

1pg3A Acetyl coa synthetase, acetylated on lys609
    31% identity, 91% coverage of query (265 bits)

Q89WV5 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
    30% identity, 93% coverage of query (256 bits)

acsA / P31638 acetyl-CoA synthetase (EC 6.2.1.1; EC 6.2.1.17) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
ACSA_CUPNH / P31638 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
    32% identity, 93% coverage of query (253 bits)

acs1 / Q2LWR8 acetate—CoA ligase (EC 6.2.1.1) from Syntrophus aciditrophicus (strain SB) (see paper)
    30% identity, 97% coverage of query (252 bits)

5gxdA / A8LRC0 Structure of acryloyl-coa lyase prpe from dinoroseobacter shibae dfl 12
    31% identity, 93% coverage of query (248 bits)

AO356_18695 Acetyl-coenzyme A synthetase (EC 6.2.1.1) from Pseudomonas fluorescens FW300-N2C3
    30% identity, 96% coverage of query (247 bits)

ACS2 / CAC41017.1 Acetyl-CoA synthetase from Zygosaccharomyces bailii (see paper)
    31% identity, 93% coverage of query (245 bits)

P78773 Probable acetyl-coenzyme A synthetase; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    31% identity, 86% coverage of query (244 bits)

Build an alignment

Build an alignment for WP_028321208.1 and 21 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

AO353_03060 Acetyl-coenzyme A synthetase (EC 6.2.1.1) from Pseudomonas fluorescens FW300-N2E3
    28% identity, 96% coverage of query (242 bits)

ACS2L_MOUSE / Q99NB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial; Acetate--CoA ligase 2; Acetyl-CoA synthetase 2; AceCS2; Acyl-CoA synthetase short-chain family member 1; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Mus musculus (Mouse) (see 3 papers)
Q99NB1 acetate-CoA ligase (EC 6.2.1.1) from Mus musculus (see paper)
    31% identity, 93% coverage of query (241 bits)

ACS2L_HUMAN / Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial; Acetate--CoA ligase 2; Acetyl-CoA synthetase 2; AceCS2; Acyl-CoA synthetase short-chain family member 1; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Homo sapiens (Human) (see 2 papers)
Q9NUB1 acetate-CoA ligase (EC 6.2.1.1) from Homo sapiens (see paper)
    32% identity, 93% coverage of query (241 bits)

ACS_ARATH / B9DGD6 Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Acetate--CoA ligase; Acetyl-CoA synthetase; EC 6.2.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
B9DGD6 acetate-CoA ligase (EC 6.2.1.1) from Arabidopsis thaliana (see paper)
    30% identity, 97% coverage of query (240 bits)

facA acetyl-coenzyme A synthetase; EC 6.2.1.1 from Emericella nidulans (see 2 papers)
    30% identity, 93% coverage of query (239 bits)

ACS2 / P52910 acetyl CoA synthetase 2 (EC 6.2.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
ACS2_YEAST / P52910 Acetyl-coenzyme A synthetase 2; Acetate--CoA ligase 2; Acyl-activating enzyme 2; EC 6.2.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P52910 acetate-CoA ligase (EC 6.2.1.1) from Saccharomyces cerevisiae (see paper)
    30% identity, 90% coverage of query (233 bits)

Msed_1456 / A4YGR1 3-hydroxypropionyl-CoA synthetase subunit (EC 6.2.1.36) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 2 papers)
HPCAS_METS5 / A4YGR1 3-hydroxypropionyl-coenzyme A synthetase; 3-hydroxypropionyl-CoA synthetase; EC 6.2.1.36 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see paper)
A4YGR1 propionate-CoA ligase (EC 6.2.1.17); 3-hydroxypropionyl-CoA synthase (EC 6.2.1.36) from Metallosphaera sedula (see 2 papers)
    30% identity, 93% coverage of query (233 bits)

ACS2 acetyl-coenzyme A synthetase 2; EC 6.2.1.1 from Candida albicans (see 2 papers)
    30% identity, 91% coverage of query (232 bits)

ACSM4_RAT / Q7TN78 Acyl-coenzyme A synthetase ACSM4, mitochondrial; Olfactory specific medium-chain acyl CoA synthetase; O-MACS; EC 6.2.1.2 from Rattus norvegicus (Rat) (see paper)
    30% identity, 91% coverage of query (232 bits)

8w0bA / Q8NJN3 Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a cyclopropyl amp ester inhibitor
    30% identity, 91% coverage of query (232 bits)

8w0cA Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a cyclopentyl ester amp inhibitor
    30% identity, 91% coverage of query (232 bits)

8w0dA Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with an isopropyl amp ester inhibitor
    30% identity, 91% coverage of query (232 bits)

8v4rA Crystal structure of acetyl-coa synthetase 2 in complex with amp and coa from candida albicans
    30% identity, 91% coverage of query (232 bits)

ACAS2 / Q9NR19 acetyl-coA synthetase (EC 6.2.1.1) from Homo sapiens (see 2 papers)
ACSA_HUMAN / Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acetyl-CoA synthetase 1; AceCS1; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Homo sapiens (Human) (see 3 papers)
Q9NR19 acetate-CoA ligase (EC 6.2.1.1) from Homo sapiens (see 5 papers)
    30% identity, 91% coverage of query (231 bits)

PGA1_c11900 Propionate--CoA ligase (EC 6.2.1.17) from Phaeobacter inhibens BS107
    29% identity, 93% coverage of query (231 bits)

7kvyA / J3KJC6 Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-ethylphosphate and co-enzyme a from coccidioides immitis rs
    30% identity, 91% coverage of query (231 bits)

8v4pA Crystal structure of acetyl-coa synthetase 2 in complex with adenosine-5'-allylphosphate from candida albicans
    30% identity, 91% coverage of query (230 bits)

8v4oA Crystal structure of acetyl-coa synthetase 2 in complex with amp from candida albicans
    30% identity, 91% coverage of query (230 bits)

8w0jA Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a propyne amp ester inhibitor
    30% identity, 91% coverage of query (230 bits)

7kdsA Crystal structure of acetyl-coa synthetase 2 in complex with adenosine-5'-propylphosphate from candida albicans
    30% identity, 91% coverage of query (230 bits)

ACSM3_MOUSE / Q3UNX5 Acyl-coenzyme A synthetase ACSM3, mitochondrial; Acyl-CoA synthetase medium-chain family member 3; Butyrate--CoA ligase 3; Butyryl-coenzyme A synthetase 3; Middle-chain acyl-CoA synthetase 3; Propionate--CoA ligase; Protein SA homolog; EC 6.2.1.2; EC 6.2.1.17 from Mus musculus (Mouse) (see 4 papers)
    29% identity, 93% coverage of query (229 bits)

prpE / Q5LPB4 propionate--CoA ligase (EC 6.2.1.17) from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (see 3 papers)
    29% identity, 93% coverage of query (226 bits)

ACSM3_HUMAN / Q53FZ2 Acyl-coenzyme A synthetase ACSM3, mitochondrial; Acyl-CoA synthetase medium-chain family member 3; Butyrate--CoA ligase 3; Butyryl-coenzyme A synthetase 3; Middle-chain acyl-CoA synthetase 3; Propionate--CoA ligase; Protein SA homolog; EC 6.2.1.2; EC 6.2.1.17 from Homo sapiens (Human) (see paper)
    27% identity, 93% coverage of query (226 bits)

7kdnA / Q4WQ02 Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate from aspergillus fumigatus
    30% identity, 90% coverage of query (224 bits)

ACSS3_HUMAN / Q9H6R3 Acyl-CoA synthetase short-chain family member 3, mitochondrial; Acetate--CoA ligase 3; Acyl-CoA synthetase short-chain family member 3; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Homo sapiens (Human) (see paper)
    30% identity, 93% coverage of query (224 bits)

7l3qA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-methylphosphate and co-enzyme a from coccidioides immitis rs
    30% identity, 90% coverage of query (224 bits)

ACSM1_BOVIN / Q9BEA2 Acyl-coenzyme A synthetase ACSM1, mitochondrial; Acyl-CoA synthetase medium-chain family member 1; Benzoate--CoA ligase; Butyrate--CoA ligase 1; Butyryl-coenzyme A synthetase 1; Lipoate-activating enzyme; Middle-chain acyl-CoA synthetase 1; XL-III; Xenobiotic/medium-chain fatty acid:CoA ligase XL-3; XM-ligase 3; EC 6.2.1.2; EC 6.2.1.25 from Bos taurus (Bovine) (see 2 papers)
    29% identity, 94% coverage of query (222 bits)

7mmzA / Q5ZZ84 Crystal structure of acetyl-coenzyme a synthetase from legionella pneumophila philadelphia 1 in complex with ethyl-amp (see paper)
    29% identity, 86% coverage of query (217 bits)

8sf3A Crystal structure of acetyl-coenzyme a synthetase from leishmania infantum (amp, acetate and coa bound)
    30% identity, 93% coverage of query (215 bits)

8u2rA / A4I093 Crystal structure of acetyl-coenzyme a synthetase from leishmania infantum (ethyl amp bound)
    31% identity, 93% coverage of query (214 bits)

8rwjD / N1P7N2 Cryoem structure of acs1 filament determined by filamentid (see paper)
    30% identity, 90% coverage of query (212 bits)

1ry2A Crystal structure of yeast acetyl-coenzyme a synthetase in complex with amp
    30% identity, 90% coverage of query (211 bits)

5k8fA Crystal structure of acetyl-coa synthetase in complex with atp and acetyl-amp from cryptococcus neoformans h99
    28% identity, 95% coverage of query (211 bits)

7l4gB / J9VFT1 Crystal structure of acetyl-coa synthetase in complex with acetyl adenylate from cryptococcus neoformans h99
    28% identity, 94% coverage of query (210 bits)

5u29A Crystal structure of cryptococcus neoformans h99 acetyl-coa synthetase in complex with ac-ams
    28% identity, 94% coverage of query (210 bits)

8w0mA Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a acetyl sulfamate amp ester inhibitor
    29% identity, 82% coverage of query (206 bits)

8w0lC Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a propyne amp ester inhibitor and coa
    30% identity, 79% coverage of query (204 bits)

8v5gA Crystal structure of acetyl-coa synthetase from cryptococcus neoformans h99 in complex with an ethylsulfamide amp inhibitor
    28% identity, 94% coverage of query (202 bits)

8g0tA Crystal structure of acetyl-coa synthetase in complex with a cyclopropyl ester amp inhibitor from cryptococcus neoformans h99
    27% identity, 97% coverage of query (202 bits)

8g0vA Crystal structure of acetyl-coa synthetase in complex with a propyne ester amp inhibitor from cryptococcus neoformans h99
    28% identity, 94% coverage of query (201 bits)

8g0uA Crystal structure of acetyl-coa synthetase in complex with an isopropyl ester amp inhibitor from cryptococcus neoformans h99
    28% identity, 94% coverage of query (201 bits)

7knoA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-ethylphosphate from cryptococcus neoformans var. Grubii serotype a (h99)
    28% identity, 94% coverage of query (201 bits)

3c5eA Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with atp
    28% identity, 91% coverage of query (201 bits)

3b7wA / Q08AH3 Crystal structure of human acyl-coa synthetase medium-chain family member 2a, with l64p mutation (see paper)
    28% identity, 91% coverage of query (201 bits)

7knpA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-butylphosphate from cryptococcus neoformans var. Grubii serotype a (h99)
    28% identity, 94% coverage of query (201 bits)

3eq6A Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in a ternary complex with products
    28% identity, 91% coverage of query (201 bits)

2wd9A Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with ibuprofen
    28% identity, 91% coverage of query (201 bits)

2vzeA Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with amp
    28% identity, 91% coverage of query (201 bits)

7kcpA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate from coccidioides posadasii c735
    31% identity, 77% coverage of query (200 bits)

ACS2A_HUMAN / Q08AH3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial; Acyl-CoA synthetase medium-chain family member 2A; Benzoate--CoA ligase; Butyrate--CoA ligase 2A; Butyryl-coenzyme A synthetase 2A; Middle-chain acyl-CoA synthetase 2A; EC 6.2.1.2; EC 6.2.1.25 from Homo sapiens (Human) (see paper)
    28% identity, 91% coverage of query (199 bits)

3dayA Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with amp-cpp
    28% identity, 91% coverage of query (199 bits)

5k8fC Crystal structure of acetyl-coa synthetase in complex with atp and acetyl-amp from cryptococcus neoformans h99
    28% identity, 95% coverage of query (197 bits)

8epsA Crystal structure of acetyl-coa synthetase in complex with an allyl ester amp inhibitor from cryptococcus neoformans h99
    28% identity, 94% coverage of query (196 bits)

5ifiA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate from cryptococcus neoformans h99
    28% identity, 94% coverage of query (196 bits)

8g0rA Crystal structure of acetyl-coa synthetase in complex with a cyclopentyl ester amp inhibitor from cryptococcus neoformans h99
    28% identity, 94% coverage of query (196 bits)

7kdnB Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate from aspergillus fumigatus
    30% identity, 77% coverage of query (195 bits)

3gpcA Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in a complex with coa
    28% identity, 91% coverage of query (194 bits)

5k85C Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate and coenzyme a from cryptococcus neoformans h99
    29% identity, 83% coverage of query (183 bits)

4wv3B / F3Y661 Crystal structure of the anthranilate coa ligase auaeii in complex with anthranoyl-amp (see paper)
    31% identity, 85% coverage of query (182 bits)

8biqB Crystal structure of acyl-coa synthetase from metallosphaera sedula in complex with acetyl-amp
    28% identity, 87% coverage of query (173 bits)

8biqA / A4YDT1 Crystal structure of acyl-coa synthetase from metallosphaera sedula in complex with acetyl-amp
    28% identity, 87% coverage of query (173 bits)

8bitA Crystal structure of acyl-coa synthetase from metallosphaera sedula in complex with coenzyme a and acetyl-amp
    28% identity, 87% coverage of query (173 bits)

4rlfB / Q93TK0 Crystal structure of a benzoate coenzyme a ligase with p-toluic acid and o-toluic acid (see paper)
    28% identity, 85% coverage of query (156 bits)

4zjzA Crystal structure of a benzoate coenzyme a ligase with benzoyl-amp
    28% identity, 84% coverage of query (154 bits)

4rmnA Crystal structure of a benzoate coenzyme a ligase with 2-thiophene carboxylic acid
    28% identity, 84% coverage of query (154 bits)

4rm2A Crystal structure of a benzoate coenzyme a ligase with 2-fluoro benzoic acid
    28% identity, 84% coverage of query (154 bits)

4rm3A Crystal structure of a benzoate coenzyme a ligase with 2-furoic acid
    28% identity, 84% coverage of query (154 bits)

6m2uA The crystal structure of benzoate coenzyme a ligase double mutant (h333a/i334a) in complex with 2-chloro-1,3-thiazole-5-carboxylate-amp
    27% identity, 84% coverage of query (152 bits)

6m2tA The crystal structure of benzoate coenzyme a ligase double mutant (h333a/i334a) in complex with 2-methyl-thiazole-5 carboxylate-amp
    27% identity, 84% coverage of query (152 bits)

4gxqA / Q13WK3,Q6ND88 Crystal structure of atp bound rpmatb-bxbclm chimera b1 (see paper)
    28% identity, 84% coverage of query (144 bits)

4CL2 / Q9S725 4-coumarate coenzyme A ligase 2 (EC 6.2.1.12) from Arabidopsis thaliana (see 2 papers)
4CL2_ARATH / Q9S725 4-coumarate--CoA ligase 2; 4CL 2; 4-coumarate--CoA ligase isoform 2; At4CL2; 4-coumaroyl-CoA synthase 2; Caffeate--CoA ligase; EC 6.2.1.12; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9S725 4-coumarate-CoA ligase (EC 6.2.1.12) from Arabidopsis thaliana (see 3 papers)
    26% identity, 88% coverage of query (135 bits)

OldD / b1805 long-chain-fatty-acid—CoA ligase (EC 6.2.1.3) from Escherichia coli K-12 substr. MG1655 (see 14 papers)
fadD / P69451 long-chain-fatty-acid—CoA ligase (EC 6.2.1.3) from Escherichia coli (strain K12) (see 3 papers)
LCFA_ECOLI / P69451 Long-chain-fatty-acid--CoA ligase; Long-chain acyl-CoA synthetase; Acyl-CoA synthetase; EC 6.2.1.3 from Escherichia coli (strain K12) (see 2 papers)
TC 4.C.1.1.4 / P69451 Long chain fatty acyl CoA synthase (ligase), (EC 6.2.1.3) from Escherichia coli (see 6 papers)
fadD long-chain-fatty-acid--CoA ligase; EC 6.2.1.3 from Escherichia coli K12 (see 8 papers)
    25% identity, 91% coverage of query (135 bits)

4CL2_TOBAC / O24146 4-coumarate--CoA ligase 2; 4CL 2; Nt4CL-19; Nt4CL-2; 4-coumaroyl-CoA synthase 2; Caffeate--CoA ligase; Cinnamate--CoA ligase; Ferulate--CoA ligase; EC 6.2.1.12; EC 6.2.1.-; EC 6.2.1.34 from Nicotiana tabacum (Common tobacco) (see 2 papers)
O24146 4-coumarate-CoA ligase (EC 6.2.1.12) from Nicotiana tabacum (see 2 papers)
    26% identity, 89% coverage of query (134 bits)

5bsvA Crystal structure of 4-coumarate:coa ligase complexed with feruloyl adenylate
    26% identity, 88% coverage of query (134 bits)

5bsuA Crystal structure of 4-coumarate:coa ligase complexed with caffeoyl adenylate
    26% identity, 88% coverage of query (134 bits)

5bstA Crystal structure of 4-coumarate:coa ligase complexed with coumaroyl adenylate
    26% identity, 88% coverage of query (134 bits)

5bsrA Crystal structure of 4-coumarate:coa ligase complexed with adenosine monophosphate and coenzyme a
    26% identity, 88% coverage of query (134 bits)

5bsmA / O24146 Crystal structure of 4-coumarate:coa ligase complexed with magnesium and adenosine triphosphate (see paper)
    26% identity, 88% coverage of query (134 bits)

LCFCS_THET8 / Q5SKN9 Long-chain-fatty-acid--CoA ligase; Long-chain fatty acyl-CoA synthetase; LC-FACS; EC 6.2.1.3 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    28% identity, 87% coverage of query (130 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory