Searching for up to 100 curated homologs for WP_028988618.1 NCBI__GCF_000423825.1:WP_028988618.1 (274 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ttg2 / GI|4336798 toluene tolerance protein Ttg2A from Pseudomonas putida (see paper)
60% identity, 96% coverage of query (326 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
59% identity, 95% coverage of query (316 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
58% identity, 92% coverage of query (311 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
58% identity, 92% coverage of query (311 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
59% identity, 92% coverage of query (311 bits)
7ch8I Cryo-em structure of p.Aeruginosa mlafebd with adp-v
58% identity, 95% coverage of query (299 bits)
YrbF / b3195 intermembrane phospholipid transport system, ATP binding subunit MlaF from Escherichia coli K-12 substr. MG1655 (see 6 papers)
MLAF_ECOLI / P63386 Intermembrane phospholipid transport system ATP-binding protein MlaF; EC 7.6.2.- from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.27.3 / P63386 Probable phospholipid import ATP-binding protein mlaF, component of ABC transporter maintaining outer membrane (OM) lipid asymmetry, MlaABCDEF (YrbABCDEF) (Malinverni and Silhavy, 2009). MlaA (VacJ) is a "spreading" protein, essential for Shigella from Escherichia coli (strain K12) (see 3 papers)
yrbF / RF|NP_417662 uncharacterized ABC transporter ATP-binding protein yrbF from Escherichia coli K12 (see paper)
57% identity, 95% coverage of query (293 bits)
7ch6C / P63386 Cryo-em structure of e.Coli mlafeb with amppnp (see paper)
57% identity, 95% coverage of query (293 bits)
6xgyA Crystal structure of e. Coli mlafb abc transport subunits in the dimeric state
57% identity, 95% coverage of query (293 bits)
7cgnB The overall structure of the mlafedb complex in atp-bound eqtall conformation (mutation of e170q on mlaf)
57% identity, 95% coverage of query (291 bits)
TC 3.A.1.27.4 / Q0SFA1 Probable bifunctional ABC transport system, component of The cholesterol uptake porter (Mohn et al., 2008). Takes up cholesterol, 5-α-cholestanol, 5-α-cholestanone, β-sitosterol, etc. (It is not established that all of these proteins comprise the system or that other gene products are not involved.) from Rhodococcus sp. (strain RHA1) (see paper)
39% identity, 90% coverage of query (187 bits)
TC 3.A.1.27.4 / Q0SD37 ABC superfamily, ATP-binding component, component of The cholesterol uptake porter (Mohn et al., 2008). Takes up cholesterol, 5-α-cholestanol, 5-α-cholestanone, β-sitosterol, etc. (It is not established that all of these proteins comprise the system or that other gene products are not involved.) from Rhodococcus sp. (strain RHA1) (see paper)
38% identity, 90% coverage of query (186 bits)
TC 3.A.1.27.5 / P63357 Probable ribonucleotide transport ATP-binding protein mkl, component of The Mce/Yrb/Mlk (Mammalian cell entry) ABC-type putative steroid uptake transporter (involved in several aspects of mycobacterial pathogenesis) from Mycobacterium tuberculosis (see 2 papers)
38% identity, 95% coverage of query (182 bits)
TGD3_ARATH / Q9AT00 Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic; ABC transporter I family member 13; ABC transporter ABCI.13; AtABCI13; Non-intrinsic ABC protein 11; AtNAP11 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.27.2 / Q9AT00 Tdg3, component of The chloroplast lipid (trigalactosyl diacyl glycerol (TDG)) transporter, Tdg1,2,3 (Lu et al., 2007). Lipids such as mono- and digalactolipids are synthesized in the endoplasmic reticulum (ER) of plant cells and transferred to the thylakoid membranes of chloroplasts. Mutations in an outer chloroplastic envelope protein with 350 aas and 7 putative TMSs in the last 250 residues may catalyze translocation as part of a lipid transfer complex from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
38% identity, 90% coverage of query (167 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
35% identity, 93% coverage of query (157 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
34% identity, 93% coverage of query (155 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
34% identity, 93% coverage of query (155 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
34% identity, 93% coverage of query (155 bits)
TC 3.A.1.27.1 / A4PCH8 Putative ATPase component of ABC transporter system aka LinL, component of The γ-hexachlorocyclohexane (γHCH) uptake permease, LinKLMN (most similar to 3.A.1.12.4, the QAT family) from Sphingobium japonicum (see paper)
36% identity, 89% coverage of query (150 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
37% identity, 80% coverage of query (139 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
37% identity, 80% coverage of query (139 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
37% identity, 80% coverage of query (139 bits)
TC 3.A.1.1.38 / Q9WYQ2 Glycerol-3-phosphate-transporting ATPase, component of Inositol phosphate porter (Rodionova et al. 2013). Binds inositol phosphate with low Kd and inositol with a lower affinity from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
34% identity, 88% coverage of query (137 bits)
TC 3.A.1.11.7 / Q97Q42 Spermidine/putrescine import ATP-binding protein PotA, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
33% identity, 83% coverage of query (137 bits)
TMOW_PELUB / Q4FL37 Trimethylamine N-oxide transport system ATP-binding protein TmoW; TMAO transport system ATP-binding protein TmoW; EC 7.6.2.9 from Pelagibacter ubique (strain HTCC1062) (see paper)
33% identity, 84% coverage of query (137 bits)
ProU / b2677 glycine betaine ABC transporter ATP binding subunit ProV (EC 7.6.2.9) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
proV / P14175 glycine betaine ABC transporter ATP binding subunit ProV (EC 7.6.2.9) from Escherichia coli (strain K12) (see 6 papers)
PROV_ECOLI / P14175 Glycine betaine/proline betaine transport system ATP-binding protein ProV from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.12.1 / P14175 ProV aka B2677, component of Glycine betaine/proline porter, ProU or ProVWX (also transports proline betaine, carnitine, dimethyl proline, homobetaine, γ-butyrobetaine and choline with low affinity) from Escherichia coli (see 6 papers)
proV / GB|AAC75724.1 glycine betaine/l-proline transport atp-binding protein prov from Escherichia coli K12 (see 6 papers)
37% identity, 81% coverage of query (137 bits)
PROV_SALTY / P17328 Glycine betaine/proline betaine transport system ATP-binding protein ProV from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
36% identity, 81% coverage of query (137 bits)
TC 3.A.1.12.6 / Q9KKE1 HutV aka HISV aka R02702 aka SMC00670, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
38% identity, 77% coverage of query (135 bits)
TC 3.A.1.3.25 / Q9CES4 Glutamine ABC transporter ATP-binding protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
31% identity, 87% coverage of query (134 bits)
TC 3.A.1.3.14 / P39456 TcyC (YckI), component of Uptake system for L-cystine from Bacillus subtilis (see 7 papers)
34% identity, 82% coverage of query (133 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
32% identity, 81% coverage of query (133 bits)
TC 3.A.1.12.9 / Q8U4S5 OtaA, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see 2 papers)
33% identity, 86% coverage of query (133 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
33% identity, 82% coverage of query (126 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
33% identity, 77% coverage of query (124 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
33% identity, 77% coverage of query (124 bits)
2olkA Abc protein artp in complex with adp-beta-s
33% identity, 77% coverage of query (124 bits)
2oljA Abc protein artp in complex with adp/mg2+
33% identity, 77% coverage of query (124 bits)
7ahhC Opua inhibited inward-facing, sbd docked
32% identity, 82% coverage of query (119 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
32% identity, 82% coverage of query (119 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
33% identity, 78% coverage of query (118 bits)
7ahdC Opua (e190q) occluded
33% identity, 74% coverage of query (118 bits)
8tzjA / Q9KVJ5 Cryo-em structure of vibrio cholerae ftse/ftsx complex (see paper)
34% identity, 77% coverage of query (116 bits)
8wm7C / Q8YZ76 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
35% identity, 80% coverage of query (116 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
33% identity, 81% coverage of query (115 bits)
5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
37% identity, 80% coverage of query (114 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
31% identity, 87% coverage of query (114 bits)
5xu1B / Q8DQF8 Structure of a non-canonical abc transporter from streptococcus pneumoniae r6 (see paper)
35% identity, 72% coverage of query (113 bits)
8w9mC Cryo-em structure of the cyanobacterial nitrate transporter nrtbcd in complex with atp
34% identity, 80% coverage of query (113 bits)
8i6rB / Q9I6C0 Cryo-em structure of pseudomonas aeruginosa ftse(e163q)x/envc complex with atp in peptidisc (see paper)
34% identity, 74% coverage of query (113 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
31% identity, 77% coverage of query (112 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
31% identity, 79% coverage of query (112 bits)
Build an alignment for WP_028988618.1 and 51 homologs with ≥ 30% identity
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8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
29% identity, 92% coverage of query (109 bits)
4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
30% identity, 80% coverage of query (109 bits)
4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
30% identity, 80% coverage of query (108 bits)
5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
29% identity, 92% coverage of query (108 bits)
8wm7D / Q8YZ75 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
33% identity, 73% coverage of query (107 bits)
8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
29% identity, 92% coverage of query (107 bits)
8iddA Cryo-em structure of mycobacterium tuberculosis atp bound ftsex/ripc complex in peptidisc
33% identity, 74% coverage of query (107 bits)
FTSE_MYCTA / A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
33% identity, 74% coverage of query (106 bits)
8igqA / O05779 Cryo-em structure of mycobacterium tuberculosis adp bound ftsex/ripc complex in peptidisc (see paper)
33% identity, 74% coverage of query (106 bits)
8w9mD Cryo-em structure of the cyanobacterial nitrate transporter nrtbcd in complex with atp
32% identity, 73% coverage of query (106 bits)
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
32% identity, 82% coverage of query (103 bits)
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
32% identity, 82% coverage of query (103 bits)
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
32% identity, 82% coverage of query (103 bits)
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
32% identity, 82% coverage of query (103 bits)
6b89A E. Coli lptb in complex with adp and novobiocin
32% identity, 82% coverage of query (103 bits)
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
32% identity, 82% coverage of query (103 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
34% identity, 82% coverage of query (103 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
35% identity, 77% coverage of query (103 bits)
FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
32% identity, 95% coverage of query (103 bits)
1g291 / Q9YGA6 Malk (see paper)
30% identity, 77% coverage of query (103 bits)
7qkrA / F2QQK6 Cryo-em structure of abc transporter ste6-2p from pichia pastoris with verapamil at 3.2 a resolution (see paper)
32% identity, 78% coverage of query (102 bits)
6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
32% identity, 82% coverage of query (102 bits)
ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
29% identity, 90% coverage of query (102 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
33% identity, 82% coverage of query (101 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
33% identity, 82% coverage of query (101 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
33% identity, 82% coverage of query (101 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
33% identity, 82% coverage of query (101 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
33% identity, 82% coverage of query (101 bits)
8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
32% identity, 81% coverage of query (101 bits)
5d3mB Folate ecf transporter: amppnp bound state
32% identity, 81% coverage of query (101 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
33% identity, 82% coverage of query (101 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
33% identity, 82% coverage of query (101 bits)
2pclA / O66646 Crystal structure of abc transporter with complex (aq_297) from aquifex aeolicus vf5
33% identity, 75% coverage of query (101 bits)
3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
35% identity, 82% coverage of query (100 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
26% identity, 89% coverage of query (100 bits)
sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
31% identity, 81% coverage of query (100 bits)
HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
30% identity, 89% coverage of query (100 bits)
8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
31% identity, 81% coverage of query (100 bits)
1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
30% identity, 88% coverage of query (100 bits)
8f5bA / P78363 Human abca4 structure in complex with amp-pnp
33% identity, 78% coverage of query (100 bits)
7e7oA / P78363 Cryo-em structure of human abca4 in nrpe-bound state (see paper)
33% identity, 82% coverage of query (99.8 bits)
ABCA4_HUMAN / P78363 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM proteinv; RmP; Retinal-specific ATP-binding cassette transporter; Stargardt disease protein; EC 7.6.2.1 from Homo sapiens (Human) (see 38 papers)
TC 3.A.1.211.2 / P78363 The retinal-specific ABC transporter (RIM protein, ABCR or ABCA4) (Stargardt's disease protein, involved in retinal/macular degeneration) in the rod outer segment. Changes in the oligomeric state of the nucleotide binding domains of ABCR are coupled to ATP hydrolysis and might represent a signal for the TMDs of ABCR to export the bound substrate (Biswas-Fiss 2006). The ABCA4 porter flips N-retinylidene-phosphatidylethanolamine, a product generated from the photobleaching of rhodopsin, from the lumen to the cytoplasmic side of disc membranes following the photobleaching of rhodopsin, insuring that retinoids do not accumulate in disc membranes (Molday, 2007; Molday et al. 2009; Tsybovsky et al. 2013). It also transports several vitamin A derivatives (Sun, 2011) and phosphatidylethanolamine in the same direction. Mutations, known to cause Stargardt disease, decrease N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine transport activities (Quazi et al. 2012). It functions as an inwardly directed retinoid flippase in the visual cycle from Homo sapiens (Human) (see 28 papers)
33% identity, 78% coverage of query (99.8 bits)
7o9wA Encequidar-bound human p-glycoprotein in complex with uic2-fab
32% identity, 78% coverage of query (99.4 bits)
7a6fA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and zosuquidar
32% identity, 78% coverage of query (99.4 bits)
7a6eA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and tariquidar
32% identity, 78% coverage of query (99.4 bits)
7a6cA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and elacridar
32% identity, 78% coverage of query (99.4 bits)
7a69A Nanodisc reconstituted human abcb1 in complex with mrk16 fab and vincristine
32% identity, 78% coverage of query (99.4 bits)
6qexA / P08183 Nanodisc reconstituted human abcb1 in complex with uic2 fab and taxol (see paper)
32% identity, 78% coverage of query (99.4 bits)
7lkpA Structure of atp-free human abca4
33% identity, 76% coverage of query (99.0 bits)
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