Searching for up to 100 curated homologs for WP_038201031.1 NCBI__GCF_000745855.1:WP_038201031.1 (440 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

hom / AAF21129.1 homoserine dehydrogenase from Methylobacillus flagellatus (see paper)
    67% identity, 100% coverage of query (583 bits)

DHOM_NEIG1 / Q5F8J4 Homoserine dehydrogenase; HDH; HSD; NAD(+)-dependent homoserine dehydrogenase; NAD(+)-dependent HSD; NgHSD; EC 1.1.1.3 from Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) (see paper)
    58% identity, 100% coverage of query (475 bits)

D8WXQ1 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
    40% identity, 97% coverage of query (329 bits)

Ga0059261_2711 homoserine dehydrogenase (EC 1.1.1.3) from Sphingomonas koreensis DSMZ 15582
    46% identity, 97% coverage of query (310 bits)

DHOM_BACSU / P19582 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Bacillus subtilis (strain 168) (see 3 papers)
P19582 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus subtilis (see paper)
    40% identity, 97% coverage of query (299 bits)

DvMF_1412 homoserine dehydrogenase (EC 1.1.1.3) from Desulfovibrio vulgaris Miyazaki F
    41% identity, 99% coverage of query (298 bits)

Q56R01 homoserine dehydrogenase (EC 1.1.1.3) from Streptomyces clavuligerus (see paper)
    42% identity, 99% coverage of query (288 bits)

DHOM_CORGL / P08499 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 2 papers)
P08499 homoserine dehydrogenase (EC 1.1.1.3) from Corynebacterium glutamicum (see 2 papers)
    41% identity, 99% coverage of query (282 bits)

6dzsA / K5BJC9 Mycobacterial homoserine dehydrogenase thra in complex with NADP
    41% identity, 99% coverage of query (260 bits)

A0A0H2WVX4 homoserine dehydrogenase (EC 1.1.1.3) from Staphylococcus aureus (see 2 papers)
    41% identity, 77% coverage of query (259 bits)

DHOM_LACLC / P52985 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Lactococcus lactis subsp. cremoris (Streptococcus cremoris) (see paper)
    35% identity, 95% coverage of query (257 bits)

P46806 homoserine dehydrogenase (EC 1.1.1.3) from Mycobacterium leprae (see paper)
    39% identity, 100% coverage of query (240 bits)

4pg7A / A0A0M3KKV6 Crystal structure of s. Aureus homoserine dehydrogenase at ph7.5 (see paper)
    39% identity, 77% coverage of query (229 bits)

D8WXQ2 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
    38% identity, 72% coverage of query (226 bits)

Q9WZ17 homoserine dehydrogenase (EC 1.1.1.3); aspartate kinase (EC 2.7.2.4) from Thermotoga maritima (see paper)
    38% identity, 78% coverage of query (206 bits)

DHOM_PSECO / P0DXC5 NAD(+)-dependent homoserine dehydrogenase; NAD(+)-dependent HSD; EC 1.1.1.3 from Pseudomonas canavaninivorans (see paper)
    32% identity, 74% coverage of query (143 bits)

Q5SL04 homoserine dehydrogenase (EC 1.1.1.3) from Thermus thermophilus (see paper)
6a0tB / Q5SL04 Homoserine dehydrogenase k99a mutant from thermus thermophilus hb8 complexed with hse and NADP+ (see paper)
    35% identity, 72% coverage of query (127 bits)

6a0sA Homoserine dehydrogenase from thermus thermophilus hb8 complexed with hse and NADPH
    35% identity, 72% coverage of query (127 bits)

2ejwA Homoserine dehydrogenase from thermus thermophilus hb8
    35% identity, 72% coverage of query (127 bits)

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Build an alignment for WP_038201031.1 and 19 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

4xb2A Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH
    29% identity, 71% coverage of query (115 bits)

DHOM_PYRHO / O58802 Homoserine dehydrogenase; HDH; HSD; HseDH; EC 1.1.1.3 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
O58802 homoserine dehydrogenase (EC 1.1.1.3) from Pyrococcus horikoshii (see paper)
4xb1A / O58802 Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH (see paper)
    28% identity, 71% coverage of query (114 bits)

Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) from Echinicola vietnamensis KMM 6221, DSM 17526
    23% identity, 71% coverage of query (69.7 bits)

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