Sites on a Tree

 

Searching for up to 100 curated homologs for WP_040912329.1 NCBI__GCF_000224785.1:WP_040912329.1 (221 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Psest_1077 acetyl-CoA:acetoacetate CoA transferase, B subunit (EC 2.8.3.8) from Pseudomonas stutzeri RCH2
    47% identity, 92% coverage of query (200 bits)

scoB / P56007 succinyl-CoA-transferase subunit B (EC 2.8.3.5) from Helicobacter pylori (strain ATCC 700392 / 26695) (see paper)
    45% identity, 93% coverage of query (192 bits)

SCO2A_RAT / Q5XIJ9 Succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial; 3-oxoacid CoA-transferase 2A; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 1; SCOT-t1; EC 2.8.3.5 from Rattus norvegicus (Rat) (see paper)
    45% identity, 94% coverage of query (189 bits)

lpsJ / AAK53493.1 beta-subunit of putative 3-oxoacid CoA-transferase from Xanthomonas campestris pv. campestris (see 4 papers)
    49% identity, 91% coverage of query (188 bits)

SCOT_DROME / Q9W058 Succinyl-CoA:3-ketoacid-coenzyme A transferase, mitochondrial; 3-oxoacid CoA-transferase; EC 2.8.3.5 from Drosophila melanogaster (Fruit fly) (see paper)
Q9W058 3-oxoacid CoA-transferase (EC 2.8.3.5) from Drosophila melanogaster (see paper)
    46% identity, 91% coverage of query (186 bits)

SCO2B_MOUSE / Q9ESL0 Succinyl-CoA:3-ketoacid coenzyme A transferase 2B, mitochondrial; 3-oxoacid CoA-transferase 2B; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 2; SCOT-t2; EC 2.8.3.5 from Mus musculus (Mouse) (see paper)
    43% identity, 93% coverage of query (186 bits)

Q9JJN4 3-oxoacid CoA-transferase (EC 2.8.3.5) from Mus musculus (see paper)
    43% identity, 93% coverage of query (186 bits)

8i3yD / Q386P1 Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
    44% identity, 93% coverage of query (185 bits)

8i40A Crystal structure of asct from trypanosoma brucei in complex with coa.
    44% identity, 93% coverage of query (185 bits)

pcaJ / P0A102 β subunit of β-ketoadipate succinyl-CoA transferase (EC 2.8.3.6) from Pseudomonas putida (see paper)
P0A102 3-oxoadipate CoA-transferase (subunit 1/2) (EC 2.8.3.6) from Pseudomonas putida (see paper)
pcaJ / GI|151428 3-oxoadipate CoA-transferase subunit B; EC 2.8.3.6 from Pseudomonas putida (see paper)
    45% identity, 90% coverage of query (184 bits)

CTFB_CLOAB / P23673 Acetoacetyl-CoA:acetate/butyrate CoA-transferase beta subunit; Butyrate--acetoacetate CoA-transferase subunit B; Coat B; EC 2.8.3.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W) (see 3 papers)
    48% identity, 90% coverage of query (184 bits)

SCOT1_PIG / Q29551 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinate-coenzyme A transferase; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Sus scrofa (Pig) (see 6 papers)
Q29551 3-oxoacid CoA-transferase (EC 2.8.3.5) from Sus scrofa (see 3 papers)
    43% identity, 94% coverage of query (184 bits)

8i3yA Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
    44% identity, 90% coverage of query (183 bits)

OXCT1 / P55809 succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) from Homo sapiens (see 4 papers)
SCOT1_HUMAN / P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Homo sapiens (Human) (see 7 papers)
P55809 3-oxoacid CoA-transferase (EC 2.8.3.5) from Homo sapiens (see 3 papers)
    44% identity, 91% coverage of query (182 bits)

SCOT2_HUMAN / Q9BYC2 Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial; 3-oxoacid CoA-transferase 2A; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase; SCOT-t; EC 2.8.3.5 from Homo sapiens (Human) (see paper)
Q9BYC2 3-oxoacid CoA-transferase (EC 2.8.3.5) from Homo sapiens (see paper)
    43% identity, 93% coverage of query (182 bits)

AtoA / b2222 acetyl-CoA:acetoacetyl-CoA transferase subunit β from Escherichia coli K-12 substr. MG1655 (see 4 papers)
atoA / P76459 acetyl-CoA:acetoacetyl-CoA transferase subunit β from Escherichia coli (strain K12) (see 2 papers)
ATOA_ECOLI / P76459 Acetate CoA-transferase subunit beta; Acetoacetyl-CoA transferase subunit beta; AA-CoA transferase subunit beta; Acetyl-CoA:acetoacetate CoA-transferase subunit beta; EC 2.8.3.8 from Escherichia coli (strain K12) (see 4 papers)
    46% identity, 91% coverage of query (182 bits)

1o9lA / Q29551 Succinate:coenzyme-a transferase (pig heart)
    44% identity, 91% coverage of query (182 bits)

3k6mC Dynamic domains of succinyl-coa:3-ketoacid-coenzyme a transferase from pig heart.
    44% identity, 91% coverage of query (182 bits)

Pf6N2E2_2112 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit B from Pseudomonas fluorescens FW300-N2E2
    49% identity, 79% coverage of query (181 bits)

2nrbA / Q29551 C28s mutant of succinyl-coa:3-ketoacid coa transferase from pig heart (see paper)
    44% identity, 91% coverage of query (181 bits)

Sama_1356 3-oxoacid CoA-transferase (EC 2.8.3.5), subunit B from Shewanella amazonensis SB2B
    48% identity, 90% coverage of query (181 bits)

3oxoE Succinyl-coa:3-ketoacid coa transferase from pig heart covalently bound to coa
    44% identity, 90% coverage of query (181 bits)

SCOT1_RAT / B2GV06 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Rattus norvegicus (Rat) (see paper)
B2GV06 3-oxoacid CoA-transferase (EC 2.8.3.5) from Rattus norvegicus (see 2 papers)
    44% identity, 93% coverage of query (180 bits)

Q9D0K2 3-oxoacid CoA-transferase (EC 2.8.3.5) from Mus musculus (see paper)
    43% identity, 91% coverage of query (178 bits)

catJ / AAC46433.1 beta-ketoadipate succinyl-CoA transferase beta-subunit from Acinetobacter baylyi (see 8 papers)
    43% identity, 90% coverage of query (174 bits)

pcaJ / Q0K4S4 adipate CoA-transferase β subunit (EC 6.2.1.5) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
    44% identity, 92% coverage of query (174 bits)

pcaJ / AAC37147.1 beta-ketoadipate succinylCoA transferase beta subunit from Acinetobacter baylyi (see 11 papers)
    43% identity, 90% coverage of query (173 bits)

Build an alignment

Build an alignment for WP_040912329.1 and 27 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

CARA_ACEWO / F1CYZ5 Caffeate CoA-transferase; Hydrocaffeyl-CoA:caffeate CoA transferase; EC 2.8.3.23 from Acetobacterium woodii (see 2 papers)
F1CYZ5 caffeate CoA-transferase (EC 2.8.3.23) from Acetobacterium woodii (see 2 papers)
    26% identity, 89% coverage of query (51.2 bits)

pct / G0VND6 propanoyl-CoA transferase monomer (EC 2.8.3.1) from Megasphaera elsdenii DSM 20460 (see 3 papers)
A0A140JTF0 propionate CoA-transferase (EC 2.8.3.1) from Megasphaera elsdenii (see paper)
    25% identity, 85% coverage of query (45.4 bits)

2ahvA / Q8X5X6 Crystal structure of acyl-coa transferase from e. Coli o157:h7 (ydif)- thioester complex with coa- 1 (see paper)
    25% identity, 85% coverage of query (42.7 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory