Searching for up to 100 curated homologs for WP_043745113.1 NCBI__GCF_000009985.1:WP_043745113.1 (344 a.a.)
Found high-coverage hits (≥70%) to 30 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Hibch / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Rattus norvegicus (see 5 papers)
HIBCH_RAT / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Rattus norvegicus (Rat) (see 2 papers)
46% identity, 100% coverage of query (305 bits)
HIBCH_HUMAN / Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Homo sapiens (Human) (see 2 papers)
43% identity, 99% coverage of query (297 bits)
3bptA / Q6NVY1 Crystal structure of human beta-hydroxyisobutyryl-coa hydrolase in complex with quercetin
43% identity, 99% coverage of query (296 bits)
PfGW456L13_2986 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens GW456-L13
43% identity, 94% coverage of query (262 bits)
PS417_13835 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas simiae WCS417
40% identity, 97% coverage of query (255 bits)
AO353_25665 3-hydroxy-isobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N2E3
42% identity, 91% coverage of query (253 bits)
Psest_2439 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas stutzeri RCH2
42% identity, 94% coverage of query (253 bits)
Pf1N1B4_4790 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N1B4
41% identity, 93% coverage of query (249 bits)
Q9SE41 enoyl-CoA hydratase (EC 4.2.1.17) from Avicennia marina (see paper)
42% identity, 83% coverage of query (243 bits)
HIBCH_NEUCR / Q1K7A4 Small ribosomal subunit protein mS47; 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see paper)
40% identity, 93% coverage of query (242 bits)
HIBC1_ARATH / Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase 1; CoA-thioester hydrolase CHY1; EC 3.1.2.-; EC 3.1.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Arabidopsis thaliana (see paper)
40% identity, 96% coverage of query (242 bits)
RR42_RS28545 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Cupriavidus basilensis FW507-4G11
43% identity, 92% coverage of query (234 bits)
bch / Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see paper)
Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus (see paper)
37% identity, 93% coverage of query (230 bits)
PGA1_c17350 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Phaeobacter inhibens BS107
41% identity, 93% coverage of query (229 bits)
4hdtA / G7CC99 Crystal structure of a carnitinyl-coa dehydratase from mycobacterium thermoresistibile (see paper)
43% identity, 97% coverage of query (223 bits)
echA9 / O53419 steroid enoyl-CoA hydratase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
40% identity, 100% coverage of query (222 bits)
EHD3 / Q5AI24 3-hydroxypropanonyl-CoA hydrolase (EC 3.1.2.4) from Candida albicans (strain SC5314 / ATCC MYA-2876) (see paper)
36% identity, 94% coverage of query (213 bits)
C3KM96 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Sinorhizobium fredii (see paper)
40% identity, 96% coverage of query (209 bits)
HIBCH_YEAST / P28817 Small ribosomal subunit protein mS47; 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
33% identity, 88% coverage of query (167 bits)
Build an alignment for WP_043745113.1 and 19 homologs with ≥ 30% identity
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3rrvB / Q743A2 Crystal structure of an enoyl-coa hydratase/isomerase from mycobacterium paratuberculosis (see paper)
28% identity, 76% coverage of query (65.9 bits)
3zwaA / P07896 Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 3s-hydroxy-hexanoyl-coa (see paper)
25% identity, 83% coverage of query (51.2 bits)
6z5oAAA Peroxisomal bifunctional enzyme
25% identity, 83% coverage of query (51.2 bits)
3zw9A Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with (2s,3s)-3-hydroxy-2- methylbutanoyl-coa
25% identity, 83% coverage of query (51.2 bits)
5omoA Crystal structure of rat peroxisomal multifunctional enzyme type-1 (rpmfe1) complexed with with 3s-hydroxy-decanoyl-coa and 3-keto- decanoyl-coa
25% identity, 83% coverage of query (51.2 bits)
5mgbA Crystal structure of rat peroxisomal multifunctional enzyme type-1 (rpmfe1) complexed with acetoacetyl-coa and NAD
25% identity, 83% coverage of query (51.2 bits)
3zwcA Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 3s-hydroxy-decanoyl-coa
25% identity, 83% coverage of query (51.2 bits)
2x58A The crystal structure of mfe1 liganded with coa
25% identity, 83% coverage of query (51.2 bits)
6zibAAA structure of rat peroxisomal multifunctional enzyme type-1 (rpmfe1) complexed with acetoacetyl-coa and nadh'
25% identity, 83% coverage of query (50.8 bits)
6zicAAA structure of rat peroxisomal multifunctional enzyme type-1 (rpmfe1) complexed with 3s-hydroxybutanoyl-coa and nadh'
25% identity, 83% coverage of query (50.8 bits)
3zwbA Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 2trans-hexenoyl-coa
25% identity, 83% coverage of query (48.5 bits)
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Lawrence Berkeley National Laboratory