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Searching for up to 100 curated homologs for WP_043747053.1 NCBI__GCF_000009985.1:WP_043747053.1 (329 a.a.)

Found high-coverage hits (≥70%) to 28 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

cobC / P21633 threonine-phosphate decarboxylase (EC 4.1.1.81) from Sinorhizobium sp. (see paper)
    46% identity, 98% coverage of query (234 bits)

cobD / P97084 L-threonine-O-3-phosphate decarboxylase subunit (EC 4.1.1.81) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
COBD_SALTY / P97084 Threonine-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase; EC 4.1.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
P97084 threonine-phosphate decarboxylase (EC 4.1.1.81) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    31% identity, 91% coverage of query (95.9 bits)

1lc8A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with its reaction intermediate
    30% identity, 91% coverage of query (94.0 bits)

1lc7A / P97084 Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with a substrate (see paper)
    30% identity, 91% coverage of query (93.6 bits)

1lkcA Crystal structure of l-threonine-o-3-phosphate decarboxylase from salmonella enterica
    30% identity, 91% coverage of query (93.6 bits)

Build an alignment

Build an alignment for WP_043747053.1 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

7szpA / A6TBC4 Crystal structure of histidinol-phosphate aminotransferase from klebsiella pneumoniae subsp. Pneumoniae (strain hs11286)
    29% identity, 89% coverage of query (92.0 bits)

1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate
    29% identity, 95% coverage of query (88.6 bits)

HisC / b2021 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
hisC / P06986 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Escherichia coli (strain K12) (see 5 papers)
HIS8_ECOLI / P06986 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; HPAT; HspAT; EC 2.6.1.9 from Escherichia coli (strain K12) (see 3 papers)
    29% identity, 95% coverage of query (87.8 bits)

1fg3A / P06986 Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
    29% identity, 95% coverage of query (87.8 bits)

1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate
    29% identity, 95% coverage of query (87.8 bits)

DVU1029 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Desulfovibrio vulgaris Hildenborough JW710
    32% identity, 85% coverage of query (85.5 bits)

DvMF_0908 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Desulfovibrio vulgaris Miyazaki F
    34% identity, 86% coverage of query (82.4 bits)

hisC / P17731 histidinol-phosphate aminotransferase; tyrosine/phenylalanine aminotransferase (promiscuous) (EC 2.6.1.1; EC 2.6.1.9) from Bacillus subtilis (strain 168) (see 4 papers)
    26% identity, 77% coverage of query (72.8 bits)

BPHYT_RS14905 Aromatic-amino-acid transaminase (EC 2.6.1.57) from Burkholderia phytofirmans PsJN
    27% identity, 77% coverage of query (65.5 bits)

HIS8_THEMA / Q9X0D0 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    24% identity, 89% coverage of query (63.5 bits)

2f8jA / Q9X0D0 Crystal structure of histidinol-phosphate aminotransferase (ec 2.6.1.9) (imidazole acetol-phosphate transferase) (tm1040) from thermotoga maritima at 2.40 a resolution
    24% identity, 89% coverage of query (63.5 bits)

HIS8_CALS4 / Q8R5Q4 Histidinol-phosphate aminotransferase; Histidine transaminase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9; EC 2.6.1.38 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
Q8R5Q4 histidine transaminase (EC 2.6.1.38) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
    25% identity, 74% coverage of query (63.2 bits)

1uu1A Complex of histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form)
    24% identity, 83% coverage of query (62.4 bits)

1h1cA Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima
    24% identity, 83% coverage of query (62.4 bits)

1uu0A Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form)
    24% identity, 83% coverage of query (62.4 bits)

BT0202 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Bacteroides thetaiotaomicron VPI-5482
    25% identity, 81% coverage of query (61.2 bits)

HIS6A_ARATH / B9DHD3 Histidinol-phosphate aminotransferase 1, chloroplastic; Gene duplicate 1-B protein; Imidazole acetol-phosphate transaminase; Protein EMBRYO DEFECTIVE 2196; Protein HISTIDINE BIOSYNTHESIS 6A; EC 2.6.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    24% identity, 89% coverage of query (58.5 bits)

orf2651 / A0A0D3RBW0 tryptophan—pyruvate aminotransferase (EC 2.6.1.99) from Streptomyces griseus (see 2 papers)
    28% identity, 87% coverage of query (58.2 bits)

8bj3A / A0A072U7F9 Crystal structure of medicago truncatula histidinol-phosphate aminotransferase (hisn6) in complex with histidinol-phosphate (see paper)
    24% identity, 89% coverage of query (57.4 bits)

oxyQ / L8EVF8 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase from Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234) (see 2 papers)
OXYQ_STRRM / Q3S8P9 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase OxyQ; PLP-dependent aminotransferase OxyQ; Reductive transaminase oxyQ; EC 2.6.1.- from Streptomyces rimosus (see paper)
    32% identity, 76% coverage of query (56.6 bits)

PGA1_c25240 histidinol-phosphate aminotransferase [EC:2.6.1.9] from Phaeobacter inhibens BS107
    27% identity, 77% coverage of query (56.2 bits)

patA / P16524 N-acetyl-L,L-diaminopimelate aminotransferase from Bacillus subtilis (strain 168) (see 3 papers)
DAPX_BACSU / P16524 Probable N-acetyl-LL-diaminopimelate aminotransferase; Putative aminotransferase A; EC 2.6.1.- from Bacillus subtilis (strain 168) (see paper)
    23% identity, 75% coverage of query (53.9 bits)

CAMYS_STRVI / Q84CG1 Capreomycidine synthase; Viomycin biosynthesis protein C; EC 4.2.1.145 from Streptomyces vinaceus (see 2 papers)
    29% identity, 86% coverage of query (51.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory