Sites on a Tree

 

Searching for up to 100 curated homologs for WP_044050603.1 NCBI__GCF_000738435.1:WP_044050603.1 (306 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BPHYT_RS25805 deoxyribose kinase (EC 2.7.1.15) from Burkholderia phytofirmans PsJN
    54% identity, 99% coverage of query (300 bits)

H281DRAFT_01116 deoxyribose kinase (EC 2.7.1.15) from Paraburkholderia bryophila 376MFSha3.1
    53% identity, 98% coverage of query (286 bits)

BT2803 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
    41% identity, 97% coverage of query (206 bits)

AO356_00950 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2C3
    41% identity, 99% coverage of query (197 bits)

Pf1N1B4_6031 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N1B4
    41% identity, 99% coverage of query (191 bits)

AO353_20835 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2E3
    40% identity, 99% coverage of query (186 bits)

BWI76_RS00290 Ribokinase (EC 2.7.1.15) from Klebsiella michiganensis M5al
    40% identity, 99% coverage of query (186 bits)

deoK / Q8XGW5 deoxyribokinase monomer (EC 2.7.1.229) from Salmonella typhi (see 4 papers)
DEOK_SALTI / P0DX97 Deoxyribokinase; dRK; ATP:2-deoxy-D-ribose 5-phosphotransferase; EC 2.7.1.229 from Salmonella typhi (see paper)
DEOK_SALTY / Q7CPF5 Deoxyribokinase; dRK; ATP:2-deoxy-D-ribose 5-phosphotransferase; EC 2.7.1.229 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    37% identity, 99% coverage of query (185 bits)

8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
    37% identity, 98% coverage of query (182 bits)

4xckA / A0A0H2UL04 Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion. (see paper)
    39% identity, 98% coverage of query (179 bits)

A0A0H2UL04 ribokinase (EC 2.7.1.15) from Vibrio cholerae (see paper)
    39% identity, 98% coverage of query (179 bits)

1rk2A E. Coli ribokinase complexed with ribose and adp, solved in space group p212121
    39% identity, 98% coverage of query (168 bits)

RbsK / b3752 ribokinase (EC 2.7.1.15) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
rbsK / P0A9J6 ribokinase (EC 2.7.1.15) from Escherichia coli (strain K12) (see 19 papers)
RBSK_ECOLI / P0A9J6 Ribokinase; RK; EC 2.7.1.15 from Escherichia coli (strain K12) (see 5 papers)
rbsK / RF|NP_418208 ribokinase from Escherichia coli K12 (see 4 papers)
    39% identity, 98% coverage of query (167 bits)

1gqtB / P0A9J6 Activation of ribokinase by monovalent cations (see paper)
    39% identity, 98% coverage of query (167 bits)

2fv7A Crystal structure of human ribokinase
    37% identity, 97% coverage of query (167 bits)

5c41A / Q9H477 Crystal structure of human ribokinase in complex with amppcp in p21 spacegroup and with 4 protomers
    37% identity, 97% coverage of query (166 bits)

6wjzA Crystal structure of human ribokinase in complex with ampcp
    37% identity, 97% coverage of query (166 bits)

6wk0B Crystal structure of human ribokinase in complex with amppcp and ribose
    37% identity, 97% coverage of query (166 bits)

5c3yA Structure of human ribokinase crystallized with amppnp
    37% identity, 97% coverage of query (166 bits)

RBSK_HUMAN / Q9H477 Ribokinase; RK; EC 2.7.1.15 from Homo sapiens (Human) (see paper)
Q9H477 ribokinase (EC 2.7.1.15) from Homo sapiens (see paper)
    38% identity, 95% coverage of query (162 bits)

5byfA Crystal structure of human ribokinase in complex with amp
    38% identity, 95% coverage of query (162 bits)

RBSK_STAAC / A0A0H2WZY4 Ribokinase; RK; EC 2.7.1.15 from Staphylococcus aureus (strain COL) (see paper)
A0A0H2WZY4 ribokinase (EC 2.7.1.15) from Staphylococcus aureus (see paper)
    36% identity, 99% coverage of query (160 bits)

RBSKI_FRUSL / P83534 Bifunctional ribokinase/ribose-5-phosphate isomerase A; EC 2.7.1.15; EC 5.3.1.6 from Fructilactobacillus sanfranciscensis (strain ATCC 27651 / DSM 20451 / JCM 5668 / CCUG 30143 / KCTC 3205 / NCIMB 702811 / NRRL B-3934 / L-12) (Lactobacillus sanfranciscensis) (see paper)
    34% identity, 99% coverage of query (159 bits)

RBSK_SCHPO / O60116 Ribokinase; RK; EC 2.7.1.15 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    35% identity, 98% coverage of query (158 bits)

BT2804 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
    34% identity, 99% coverage of query (151 bits)

HSERO_RS11500 Ribokinase (EC 2.7.1.15) from Herbaspirillum seropedicae SmR1
    37% identity, 97% coverage of query (150 bits)

6a8aA / A0A3S7X0F5 Ribokinase from leishmania donovani with atp (see paper)
    34% identity, 97% coverage of query (148 bits)

RBSK_LEIMA / E9AD19 Ribokinase; RK; EC 2.7.1.15 from Leishmania major (see paper)
    34% identity, 97% coverage of query (148 bits)

6a8cA Ribokinase from leishmania donovani with adp
    34% identity, 97% coverage of query (148 bits)

6a8bA Ribokinase from leishmania donovani with amppcp
    34% identity, 97% coverage of query (148 bits)

6znxC / A0A0B0SD75 Ribokinase from thermus species
    35% identity, 91% coverage of query (145 bits)

Q8NQR0 ribokinase (EC 2.7.1.15) from Corynebacterium glutamicum (see paper)
    34% identity, 96% coverage of query (141 bits)

SMc01103 Ribokinase (EC 2.7.1.15) from Sinorhizobium meliloti 1021
    33% identity, 98% coverage of query (126 bits)

6ilsB / A1A6H3 Structure of arabidopsis thaliana ribokinase complexed with ribose and atp (see paper)
    32% identity, 98% coverage of query (118 bits)

RBSK / A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see 2 papers)
RBSK_ARATH / A1A6H3 Ribokinase; AtRBSK; RK; EC 2.7.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see paper)
    32% identity, 98% coverage of query (117 bits)

Build an alignment

Build an alignment for WP_044050603.1 and 35 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

RBSK_YEAST / P25332 Ribokinase; RK; EC 2.7.1.15 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    28% identity, 97% coverage of query (104 bits)

SquV / b3883 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yihV / P32143 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli (strain K12) (see 2 papers)
SQUV_ECOLI / P32143 Sulfofructose kinase; SF kinase; EC 2.7.1.184 from Escherichia coli (strain K12) (see 2 papers)
    27% identity, 98% coverage of query (92.4 bits)

7ag6A / P32143 Crystal structure of sf kinase yihv from e. Coli in complex with sulfofructose (sf), adp-mg (see paper)
    27% identity, 98% coverage of query (92.4 bits)

7agkA Crystal structure of e. Coli sf kinase (yihv) in complex with product sulfofructose phosphate (sfp)
    27% identity, 98% coverage of query (92.4 bits)

7aghA Crystal structure of sf kinase yihv from e. Coli in complex with amppnp-mg
    27% identity, 98% coverage of query (91.3 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    29% identity, 90% coverage of query (87.8 bits)

SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    29% identity, 90% coverage of query (87.4 bits)

SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
    28% identity, 86% coverage of query (85.9 bits)

Q9YG89 6-phosphofructokinase (EC 2.7.1.11) from Aeropyrum pernix (see 2 papers)
    29% identity, 96% coverage of query (85.9 bits)

SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
    29% identity, 90% coverage of query (84.3 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    27% identity, 89% coverage of query (84.3 bits)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    27% identity, 89% coverage of query (84.0 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    28% identity, 89% coverage of query (84.0 bits)

Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    26% identity, 89% coverage of query (82.8 bits)

3in1A / P77493 Crystal structure of a putative ribokinase in complex with adp from e.Coli
    25% identity, 89% coverage of query (82.0 bits)

YdjH / b1772 L-glycero-L-galacto-octuluronate kinase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
ydjH / P77493 L-glycero-L-galacto-octuluronate kinase from Escherichia coli (strain K12) (see 2 papers)
    25% identity, 89% coverage of query (82.0 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    27% identity, 89% coverage of query (80.9 bits)

P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
    27% identity, 89% coverage of query (80.1 bits)

Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    27% identity, 89% coverage of query (80.1 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    26% identity, 89% coverage of query (79.3 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    27% identity, 89% coverage of query (79.0 bits)

KDGK_BACSU / P50845 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Bacillus subtilis (strain 168) (see paper)
    27% identity, 99% coverage of query (78.2 bits)

3ikhA / A6T989 Crystal structure of ribokinase in complex with atp and glycerol in the active site from klebsiella pneumoniae
    27% identity, 99% coverage of query (78.2 bits)

3i3yD Crystal structure of ribokinase in complex with d-ribose from klebsiella pneumoniae
    27% identity, 99% coverage of query (77.8 bits)

TK2029 / Q5JDG9 α-D-ribose-1-phosphate 5-kinase (ADP) (EC 2.7.1.212) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
R1PKD_THEKO / Q5JDG9 ADP-dependent ribose-1-phosphate kinase; ADP-R1P kinase; ADP:alpha-D-ribose-1-phosphate 5-phosphotransferase; Alpha-D-ribose-1-phosphate 5-kinase (ADP); EC 2.7.1.212 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    25% identity, 100% coverage of query (76.6 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    28% identity, 89% coverage of query (73.6 bits)

P71913 ribokinase (EC 2.7.1.15) from Mycobacterium tuberculosis (see paper)
    33% identity, 90% coverage of query (73.6 bits)

SCRK2_MAIZE / Q6XZ78 Fructokinase-2; ZmFRK2; EC 2.7.1.4 from Zea mays (Maize)
    24% identity, 89% coverage of query (72.8 bits)

3go6A / P71913 Crystal structure of m. Tuberculosis ribokinase (rv2436) in complex with ribose and amp-pnp
    33% identity, 89% coverage of query (72.8 bits)

3go6B Crystal structure of m. Tuberculosis ribokinase (rv2436) in complex with ribose and amp-pnp
    33% identity, 89% coverage of query (72.8 bits)

cscK / GB|CAA57218.2 fructokinase; EC 2.7.1.4 from Escherichia coli (see paper)
    26% identity, 87% coverage of query (72.4 bits)

Dshi_2797 Fructokinase (EC 2.7.1.4) from Dinoroseobacter shibae DFL-12
    30% identity, 87% coverage of query (70.9 bits)

NK_METJA / Q57849 Nucleoside kinase; NK; ATP-dependent nucleoside monophosphokinase; Cytidine kinase; Guanosine-inosine kinase; EC 2.7.1.213; EC 2.7.1.73 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
    22% identity, 99% coverage of query (67.8 bits)

2c49A / Q57849 Crystal structure of methanocaldococcus jannaschii nucleoside kinase - an archaeal member of the ribokinase family (see paper)
    22% identity, 99% coverage of query (67.8 bits)

PFKB_THETC / D9TT10 ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase; EC 2.7.1.11 from Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (see paper)
    23% identity, 87% coverage of query (67.8 bits)

yeiC / Q1R9Q6 pseudouridine kinase (EC 2.7.1.83) from Escherichia coli (strain UTI89 / UPEC) (see 2 papers)
    23% identity, 99% coverage of query (67.4 bits)

7w93A / A0A140N873 Crystal structure of e.Coli pseudouridine kinase psuk complexed with n1-methyl-pseudouridine (see paper)
    23% identity, 92% coverage of query (66.6 bits)

PsuK / b2166 putative pseudouridine kinase (EC 2.7.1.83) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PSUK_ECOLI / P30235 Pseudouridine kinase; EC 2.7.1.83 from Escherichia coli (strain K12) (see paper)
P30235 pseudouridine kinase (EC 2.7.1.83) from Escherichia coli (see paper)
    23% identity, 92% coverage of query (66.6 bits)

7vtfA Cytidine bound structure of pseudouridine kinase (puki) from escherichia coli strain b
    25% identity, 88% coverage of query (66.2 bits)

RR42_RS28860 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus basilensis FW507-4G11
    29% identity, 89% coverage of query (65.9 bits)

7vteA Uridine bound structure of pseudouridine kinase (puki) from escherichia coli strain b
    25% identity, 81% coverage of query (64.3 bits)

3kzhA / Q8XKB8 Crystal structure of a putative sugar kinase from clostridium perfringens
    25% identity, 82% coverage of query (63.9 bits)

Q0K080 dehydrogluconokinase (EC 2.7.1.13); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus necator (see paper)
    26% identity, 88% coverage of query (63.9 bits)

6xk2A / J9VQ51 Crystal structure of ribokinase from cryptococcus neoformans var. Grubii serotype a in complex with adp
    25% identity, 98% coverage of query (62.8 bits)

CCNA_01356 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Caulobacter crescentus NA1000
iolC-DUF2090 / A0A0H3C6B4 bifunctional 5-dehydro-2-deoxygluconokinase/5-dehydro-2-deoxyphosphogluconate aldolase (EC 2.7.1.92; EC 4.1.2.29) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 3 papers)
    25% identity, 99% coverage of query (62.0 bits)

Q4KD57 2-ketogluconokinase (EC 2.7.1.13) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    24% identity, 85% coverage of query (60.1 bits)

A0A0H3AER7 fructokinase (EC 2.7.1.4) from Vibrio cholerae (see paper)
    25% identity, 90% coverage of query (59.7 bits)

5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
    25% identity, 90% coverage of query (59.7 bits)

5yggA / A0A0H3AER7 Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
    24% identity, 90% coverage of query (57.8 bits)

7vskA Crystal structure of e.Coli pseudouridine kinase psuk complexed with pseudouridine.
    23% identity, 89% coverage of query (56.6 bits)

STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
    27% identity, 89% coverage of query (55.8 bits)

1tz3A / Q8ZKR2 Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
    27% identity, 89% coverage of query (54.7 bits)

1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog
    27% identity, 89% coverage of query (54.7 bits)

3iq0B / A0A0H2VDX9 Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
    24% identity, 83% coverage of query (54.3 bits)

4lbxA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with cytidine
    26% identity, 83% coverage of query (54.3 bits)

4k8kA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 1-(4-methoxyphenyl)-1-cyclopropane and 2- aminoperimidine
    26% identity, 83% coverage of query (54.3 bits)

4lc4A Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with guanosine
    27% identity, 82% coverage of query (54.3 bits)

4kbeA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with benzoguanamine
    27% identity, 82% coverage of query (54.3 bits)

4kanA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetic acid
    27% identity, 82% coverage of query (54.3 bits)

4kalA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with quinoline-3-carboxylic acid
    27% identity, 82% coverage of query (54.3 bits)

4kahA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 4-bromo-1h-pyrazole
    27% identity, 82% coverage of query (54.3 bits)

4kadA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n1-(2.3-dihydro-1h-inden-5-yl)acetam
    27% identity, 82% coverage of query (54.3 bits)

4k9iA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with norharmane
    27% identity, 82% coverage of query (54.3 bits)

4k9cA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n-(hydroxymethyl)benzamide and 4-methyl-3,4- dihydro-2h-1,4-benzoxazine-7-carboxylic acid
    27% identity, 82% coverage of query (54.3 bits)

4k93A Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n-(hydroxymethyl)benzamide
    27% identity, 82% coverage of query (54.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory