Searching for up to 100 curated homologs for WP_047092224.1 NCBI__GCF_001013305.1:WP_047092224.1 (530 a.a.)
Found high-coverage hits (≥70%) to 31 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
GLSL_HUMAN / Q9UI32 Glutaminase liver isoform, mitochondrial; GLS; L-glutaminase; L-glutamine amidohydrolase; EC 3.5.1.2 from Homo sapiens (Human) (see 3 papers)
45% identity, 90% coverage of query (441 bits)
GLSL_MOUSE / Q571F8 Glutaminase liver isoform, mitochondrial; GLS; L-glutaminase; L-glutamine amidohydrolase; LGA; EC 3.5.1.2 from Mus musculus (Mouse) (see 2 papers)
45% identity, 90% coverage of query (439 bits)
Gls2 / P28492 glutaminase subunit (EC 3.5.1.38) from Rattus norvegicus (see paper)
45% identity, 90% coverage of query (439 bits)
5uqeD / O94925 Multidomain structure of human kidney-type glutaminase(kga/gls) (see paper)
43% identity, 94% coverage of query (435 bits)
GLSK_MOUSE / D3Z7P3 Glutaminase kidney isoform, mitochondrial; GLS; EC 3.5.1.2 from Mus musculus (Mouse) (see 6 papers)
43% identity, 95% coverage of query (435 bits)
GLSK_RAT / P13264 Glutaminase kidney isoform, mitochondrial; GLS; K-glutaminase; L-glutamine amidohydrolase; EC 3.5.1.2 from Rattus norvegicus (Rat) (see 6 papers)
P13264 glutaminase (EC 3.5.1.2) from Rattus norvegicus (see paper)
43% identity, 95% coverage of query (434 bits)
8gwrB Near full length kidney type glutaminase in complex with 2,2-dimethyl- 2,3-dihydrobenzo[a] phenanthridin-4(1h)-one (ddp)
43% identity, 95% coverage of query (434 bits)
O94925 glutaminase kidney isoform small subunit (EC 3.5.1.38) from Homo sapiens (see 6 papers)
GLSK_HUMAN / O94925 Glutaminase kidney isoform, mitochondrial; GLS; K-glutaminase; L-glutamine amidohydrolase; EC 3.5.1.2 from Homo sapiens (Human) (see 13 papers)
O94925 glutaminase (EC 3.5.1.2) from Homo sapiens (see 4 papers)
42% identity, 97% coverage of query (432 bits)
8t0zA / Q9UI32 Human liver-type glutaminase (k253a) with l-gln, filamentous form (see paper)
46% identity, 72% coverage of query (372 bits)
8jubA Crystal structure of glutaminasE C in complex with compound 27
46% identity, 72% coverage of query (368 bits)
6loxA Crystal structure of human glutaminase with macrocyclic inhibitor
44% identity, 76% coverage of query (366 bits)
6umdB Crystal structure of human gac in complex with inhibitor upgl00012
44% identity, 76% coverage of query (366 bits)
6ul9B Crystal structure of human gac in complex with inhibitor upgl00023
44% identity, 76% coverage of query (366 bits)
5fi7A Crystal structure of human gac in complex with inhibitor upgl_00015: 2-phenyl-~{n}-[5-[(3~{s})-3-[[5-(2-phenylethanoylamino)-1,3,4- thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]ethanamide
44% identity, 76% coverage of query (366 bits)
5fi6A Crystal structure of human gac in complex with inhibitor upgl_00011: 2-phenyl-~{n}-[5-[[(3~{s})-1-[5-(2-phenylethanoylamino)-1,3,4- thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2- yl]ethanamide
44% identity, 76% coverage of query (366 bits)
5fi2A Crystal structure of human gac in complex with inhibitor upgl_00009: 2-phenyl-~{n}-[5-[[(3~{r})-1-[5-(2-phenylethanoylamino)-1,3,4- thiadiazol- 2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2- yl]ethanamide
44% identity, 76% coverage of query (366 bits)
5w2jB Crystal structure of dimeric form of mouse glutaminasE C
44% identity, 76% coverage of query (366 bits)
8jueA Crystal structure of glutaminasE C in complex with compound 11
44% identity, 76% coverage of query (365 bits)
6umfA Crystal structure of human gac in complex with inhibitor upgl00012
44% identity, 76% coverage of query (364 bits)
6umcB Crystal structure of human gac in complex with inhibitor upgl00012
44% identity, 76% coverage of query (364 bits)
6uljA Crystal structure of human gac in complex with inhibitor upgl00012
44% identity, 76% coverage of query (364 bits)
6ulaA Crystal structure of human gac in complex with inhibitor upgl00012
44% identity, 76% coverage of query (364 bits)
6ukbA Crystal structure of human gac in complex with inhibitor upgl00012
44% identity, 76% coverage of query (364 bits)
6ujmA Crystal structure of human gac in complex with inhibitor upgl00013
44% identity, 76% coverage of query (364 bits)
6ujgA Crystal structure of human gac in complex with inhibitor upgl00012
44% identity, 76% coverage of query (364 bits)
5wj6A Crystal structure of glutaminasE C in complex with inhibitor 2-phenyl- n-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}amino) piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide (upgl-00004)
44% identity, 76% coverage of query (364 bits)
5i94A Crystal structure of human glutaminasE C in complex with the inhibitor upgl-00019
44% identity, 76% coverage of query (364 bits)
8bslA Human gls in complex with compound 12
43% identity, 76% coverage of query (359 bits)
3ss4A Crystal structure of mouse glutaminasE C, phosphate-bound form
45% identity, 72% coverage of query (355 bits)
6uk6A Crystal structure of human gac in complex with inhibitor upgl00018
43% identity, 76% coverage of query (352 bits)
5hl1A Crystal structure of glutaminasE C in complex with inhibitor cb-839
42% identity, 76% coverage of query (346 bits)
Build an alignment for WP_047092224.1 and 31 homologs with ≥ 30% identity
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Lawrence Berkeley National Laboratory