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Searching for up to 100 curated homologs for WP_048080437.1 NCBI__GCF_000745485.1:WP_048080437.1 (226 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TPIS_METBR / O74025 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Methanobacterium bryantii (see paper)
O74025 triose-phosphate isomerase (EC 5.3.1.1) from Methanobacterium bryantii (see paper)
    98% identity, 100% coverage of query (437 bits)

B6YUE5 triose-phosphate isomerase (EC 5.3.1.1) from Thermococcus onnurineus (see paper)
    62% identity, 100% coverage of query (292 bits)

tpiA / P62003 triose phosphate isomerase subunit (EC 5.3.1.1) from Pyrococcus woesei (see paper)
TPIS_PYRWO / P62003 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Pyrococcus woesei (see 2 papers)
P62002 triose-phosphate isomerase (EC 5.3.1.1) from Pyrococcus furiosus (see paper)
P62003 triose-phosphate isomerase (EC 5.3.1.1) from Pyrococcus woesei (see 2 papers)
    62% identity, 100% coverage of query (286 bits)

1hg3A / P62003 Crystal structure of tetrameric tim from pyrococcus woesei. (see paper)
    62% identity, 97% coverage of query (284 bits)

Q12UK2 triose-phosphate isomerase (EC 5.3.1.1) from Methanococcoides burtonii (see paper)
    59% identity, 97% coverage of query (267 bits)

tpiA / Q58923 triosephosphate isomerase monomer (EC 5.3.1.1) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
TPIS_METJA / Q58923 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q58923 triose-phosphate isomerase (EC 5.3.1.1) from Methanocaldococcus jannaschii (see 2 papers)
    57% identity, 96% coverage of query (259 bits)

Q97VM8 triose-phosphate isomerase (EC 5.3.1.1) from Saccharolobus solfataricus (see paper)
    42% identity, 96% coverage of query (194 bits)

1w0mA / Q8NKN9 Triosephosphate isomerase from thermoproteus tenax (see paper)
    47% identity, 95% coverage of query (178 bits)

TPIS_THETK / Q8NKN9 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1) (see paper)
Q8NKN9 triose-phosphate isomerase (EC 5.3.1.1) from Thermoproteus tenax (see 2 papers)
    47% identity, 95% coverage of query (178 bits)

Q9HLB6 triose-phosphate isomerase (EC 5.3.1.1) from Thermoplasma acidophilum (see paper)
    36% identity, 94% coverage of query (139 bits)

5csrC / Q9HLB6 Crystal structure of triosephosphate isomerase from thermoplasma acidophilium (see paper)
    36% identity, 94% coverage of query (139 bits)

5cssA Crystal structure of triosephosphate isomerase from thermoplasma acidophilum with glycerol 3-phosphate
    36% identity, 94% coverage of query (139 bits)

Build an alignment

Build an alignment for WP_048080437.1 and 12 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

tpi1 / CAD98875.1 triose phosphate isomerase from Klebsiella pneumoniae (see paper)
    28% identity, 72% coverage of query (48.9 bits)

TPIS_PARBA / Q96VN5 Triosephosphate isomerase; TIM; Triose-phosphate isomerase; EC 5.3.1.1 from Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis) (see paper)
    25% identity, 90% coverage of query (45.8 bits)

5eywA / K0E682 Crystal structure of litopenaeus vannamei triosephosphate isomerase complexed with 2-phosphoglycolic acid (see paper)
    26% identity, 76% coverage of query (44.3 bits)

1ssgA / P00940 Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase (see paper)
    25% identity, 74% coverage of query (44.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory