Sites on a Tree

 

Searching for up to 100 curated homologs for WP_048081445.1 NCBI__GCF_000745485.1:WP_048081445.1 (258 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

gno / P50199 D-gluconate 5-dehydrogenase monomer from Gluconobacter oxydans (strain 621H) (see paper)
GNO_GLUOX / P50199 Gluconate 5-dehydrogenase; D-gluconate 5-dehydrogenase (NADP); Gluconate:NADP 5-oxidoreductase; GNO; EC 1.1.1.- from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
    40% identity, 99% coverage of query (179 bits)

A0A0M4UR95 L-xylulose reductase (EC 1.1.1.10) from Rhizomucor pusillus (see paper)
    35% identity, 98% coverage of query (172 bits)

5u9pB / B4EEX4 Crystal structure of a gluconate 5-dehydrogenase from burkholderia cenocepacia j2315 in complex with NADP and tartrate
    38% identity, 98% coverage of query (165 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    39% identity, 95% coverage of query (164 bits)

Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
    39% identity, 95% coverage of query (164 bits)

7x5jC / A0A520KTT2 Acp-dependent oxoacyl reductase
    38% identity, 97% coverage of query (164 bits)

6vspB / H9XP47 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a (see paper)
    38% identity, 95% coverage of query (164 bits)

budC / H9XP47 meso-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) from Serratia marcescens (see paper)
MBDH_SERMA / H9XP47 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens (see 3 papers)
    38% identity, 95% coverage of query (164 bits)

6xewA Structure of serratia marcescens 2,3-butanediol dehydrogenase
    38% identity, 95% coverage of query (164 bits)

6vspA Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a
    38% identity, 95% coverage of query (164 bits)

3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
    39% identity, 95% coverage of query (163 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    38% identity, 97% coverage of query (160 bits)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    37% identity, 97% coverage of query (157 bits)

uxaD / Q9WYS2 fructuronate reductase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    35% identity, 99% coverage of query (156 bits)

5wuwA / A0A192ICX3 Serratia marcescens short-chain dehydrogenase/reductase f98l/f202l mutant (see paper)
    36% identity, 97% coverage of query (155 bits)

BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
    33% identity, 97% coverage of query (154 bits)

7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
    33% identity, 97% coverage of query (154 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    36% identity, 97% coverage of query (154 bits)

1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
    35% identity, 98% coverage of query (152 bits)

zgc:113054 / Q5BLE6 gadusol synthase from Danio rerio (see 2 papers)
    32% identity, 97% coverage of query (151 bits)

YjgU / b4266 5-keto-D-gluconate 5-reductase (EC 1.1.1.69) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
idnO / P0A9P9 5-keto-D-gluconate 5-reductase (EC 1.1.1.69) from Escherichia coli (strain K12) (see 4 papers)
IDNO_ECOLI / P0A9P9 5-keto-D-gluconate 5-reductase; EC 1.1.1.69 from Escherichia coli (strain K12) (see paper)
    34% identity, 100% coverage of query (150 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    38% identity, 97% coverage of query (150 bits)

4za2D Crystal structure of pectobacterium carotovorum 2-keto-3-deoxy-d- gluconate dehydrogenase complexed with NAD+ (see paper)
    38% identity, 98% coverage of query (150 bits)

5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    32% identity, 98% coverage of query (150 bits)

bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
    32% identity, 98% coverage of query (149 bits)

SDR_YARLI / Q6CEE9 Probable NADP-dependent mannitol dehydrogenase; MtDH; Mannitol 2-dehydrogenase [NADP(+)]; Short chain dehydrogenase/reductase; YlSDR; EC 1.1.1.138 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) (see paper)
    35% identity, 98% coverage of query (149 bits)

YfeF / b2426 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
ucpA / P37440 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli (strain K12) (see 6 papers)
    37% identity, 97% coverage of query (149 bits)

SOU1_CANAL / P87219 Sorbose reductase SOU1; Sorbitol utilization protein SOU1; EC 1.1.1.289 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see paper)
P87219 sorbose reductase (EC 1.1.1.289) from Candida albicans (see paper)
SOU1 / GI|2183243 Sorbose reductase SOU1; EC 1.1.1.289 from Candida albicans (see 2 papers)
    35% identity, 98% coverage of query (149 bits)

PHGR_EUBOX / P57793 Phloroglucinol reductase; EC 1.3.1.57 from Eubacterium oxidoreducens (see paper)
    34% identity, 99% coverage of query (149 bits)

YgeC / b2842 putative 2-keto-3-deoxy-D-gluconate dehydrogenase (EC 1.1.1.127) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
kduD / P37769 putative 2-keto-3-deoxy-D-gluconate dehydrogenase (EC 1.1.1.127) from Escherichia coli (strain K12) (see 5 papers)
KDUD_ECOLI / P37769 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-deoxy-D-gluconate 3-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; 20-ketosteroid reductase; EC 1.1.1.127; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
    38% identity, 97% coverage of query (148 bits)

W5VJM4 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
    34% identity, 97% coverage of query (147 bits)

GOLD_LISIN / Q92EU6 NAD-dependent glycerol dehydrogenase; Dha-forming NAD-dependent glycerol dehydrogenase; EC 1.1.1.6 from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) (see paper)
    36% identity, 98% coverage of query (147 bits)

8cxaA / A0QVD5 Crystal structure of 3-oxoacyl-[acyl-carrier-protein] reductase from mycobacterium smegmatis with bound NAD
    37% identity, 97% coverage of query (147 bits)

PLH6_FORAG / T2KLZ8 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-deoxy-D-gluconate 3-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; P6_dehydrogenase; Polysaccharide utilization locus H protein P6; PUL H protein P6; EC 1.1.1.127 from Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) (see paper)
    33% identity, 98% coverage of query (147 bits)

dhuD / Q8E370 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase monomer (EC 1.1.1.127) from Streptococcus agalactiae serotype III (strain NEM316) (see paper)
    33% identity, 99% coverage of query (146 bits)

hpsO / Q46N54 (S)-sulfopropanediol 2-dehydrogenase from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
    32% identity, 97% coverage of query (146 bits)

barS1 / Q9LBV3 A-factor type γ-butyrolactone 6-reductase (6S-forming) monomer (EC 1.1.1.413) from Streptomyces virginiae (see paper)
BARS1_STRVG / Q9LBV3 A-factor type gamma-butyrolactone 1'-reductase (1S-forming); 6-dehydro-VB-A reductase; Butyrolactone autoregulator synthesis; EC 1.1.1.413 from Streptomyces virginiae (Streptomyces cinnamonensis) (see 2 papers)
    35% identity, 98% coverage of query (146 bits)

kduD / Q05528 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127) from Dickeya dadantii (strain 3937) (see 3 papers)
KDUD_DICD3 / Q05528 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; EC 1.1.1.127 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    36% identity, 98% coverage of query (145 bits)

ptmO8 / D8L2W5 ent-kauranol 7β-dehydrogenase from Streptomyces platensis (see paper)
    35% identity, 97% coverage of query (145 bits)

W5VJJ6 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens (see paper)
    34% identity, 97% coverage of query (144 bits)

FABG_SYNY3 / P73574 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100 from Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa) (see paper)
    37% identity, 97% coverage of query (144 bits)

NMTDH_ALTAL / P0C0Y4 NADP-dependent mannitol dehydrogenase; MtDH; Mannitol 2-dehydrogenase [NADP(+)]; Allergen Alt a 8; EC 1.1.1.138 from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 2 papers)
P0C0Y4 mannitol 2-dehydrogenase (NADP+) (EC 1.1.1.138) from Alternaria alternata (see paper)
    34% identity, 100% coverage of query (144 bits)

1g6kA / P40288 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+
    35% identity, 98% coverage of query (143 bits)

A0A1H3NGY9 gluconate 5-dehydrogenase (EC 1.1.1.69) from Lentibacter algarum (see paper)
    37% identity, 98% coverage of query (143 bits)

ped / Q5P5I4 1-phenylethanol dehydrogenase subunit (EC 1.1.1.311) from Aromatoleum aromaticum (strain EbN1) (see paper)
PED_AROAE / Q5P5I4 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain DSM 19018 / LMG 30748 / EbN1) (Azoarcus sp. (strain EbN1)) (see 2 papers)
Q5P5I4 (S)-1-phenylethanol dehydrogenase (EC 1.1.1.311) from Azoarcus sp. (see paper)
ped / CAI07428.1 (S)-1-Phenylethanol dehydrogenase from Aromatoleum aromaticum EbN1 (see 4 papers)
    38% identity, 96% coverage of query (143 bits)

2ewmB / Q5P5I4 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 (see paper)
    38% identity, 96% coverage of query (143 bits)

xecD / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.268) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 5 papers)
HCDR1_XANP2 / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase; R-HPCDH; 2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase; Aliphatic epoxide carboxylation component III; Epoxide carboxylase component III; RHPCDH1; EC 1.1.1.268 from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 7 papers)
Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268) from Xanthobacter autotrophicus (see 4 papers)
2cfcA / Q56840 Structural basis for stereo selectivity in the (r)- and (s)- hydroxypropylethane thiosulfonate dehydrogenases (see paper)
    38% identity, 97% coverage of query (143 bits)

CHCB2_CORCT / P0DXE1 Cis-4-hydroxycyclohexanecarboxylate dehydrogenase; Cis-4-hydroxyCHCA dehydrogenase; EC 1.1.1.438 from Corynebacterium cyclohexanicum (Sinomonas cyclohexanicum) (see paper)
    36% identity, 97% coverage of query (142 bits)

TRN1_COCOF / A7DY56 Tropinone reductase; EC 1.1.1.206; EC 1.1.1.236 from Cochlearia officinalis (Common scurvygrass) (see paper)
A7DY56 tropinone reductase I (EC 1.1.1.206); tropinone reductase II (EC 1.1.1.236) from Cochlearia officinalis (see paper)
    33% identity, 99% coverage of query (142 bits)

DHG_PRIMG / P40288 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) (see paper)
P40288 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Priestia megaterium (see 9 papers)
    35% identity, 98% coverage of query (141 bits)

CHCB1_CORCT / P0DXE0 Trans-4-hydroxycyclohexanecarboxylate dehydrogenase; Trans-4-hydroxyCHCA dehydrogenase; 4-hydroxycyclohexanecarboxylate dehydrogenase; EC 1.1.1.226 from Corynebacterium cyclohexanicum (Sinomonas cyclohexanicum) (see 2 papers)
    37% identity, 95% coverage of query (141 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    36% identity, 97% coverage of query (141 bits)

6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
    36% identity, 98% coverage of query (141 bits)

W5VJT8 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
    33% identity, 97% coverage of query (140 bits)

Q9WYD3 D-arabinitol 2-dehydrogenase (EC 1.1.1.250) from Thermotoga maritima (see paper)
    35% identity, 100% coverage of query (140 bits)

SILD_FORIN / Q94KL7 Secoisolariciresinol dehydrogenase; EC 1.1.1.331 from Forsythia intermedia (Border forsythia) (Forsythia suspensa x Forsythia viridissima) (see paper)
    33% identity, 98% coverage of query (140 bits)

LINX_SPHIU / D4Z260 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
    35% identity, 97% coverage of query (140 bits)

3ay6B / P39485 Crystal structure of bacillus megaterium glucose dehydrogenase 4 a258f mutant in complex with nadh and d-glucose (see paper)
    34% identity, 98% coverage of query (140 bits)

P39485 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Priestia megaterium (see paper)
    34% identity, 98% coverage of query (140 bits)

P39482 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Priestia megaterium (see paper)
    35% identity, 98% coverage of query (140 bits)

3o03A Quaternary complex structure of gluconate 5-dehydrogenase from streptococcus suis type 2 (see paper)
    33% identity, 98% coverage of query (140 bits)

7dlmA / G8BHG6 Short chain dehydrogenase (scr) crystal structure with NADPH (see paper)
    33% identity, 98% coverage of query (139 bits)

7vyqA Short chain dehydrogenase (scr) cryoem structure with NADP and ethyl 4-chloroacetoacetate
    33% identity, 98% coverage of query (139 bits)

A0A545BBR2 (1R,2S)-ephedrine 1-dehydrogenase (EC 1.1.1.423) from Arthrobacter sp. TS-15 (see paper)
    36% identity, 97% coverage of query (138 bits)

GMDH_GLUOX / Q5FPE5 Glucose 1-dehydrogenase; EC 1.1.1.119 from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
    35% identity, 97% coverage of query (138 bits)

8w0oA / M9TFE3 Gdh-105 crystal structure
    33% identity, 98% coverage of query (138 bits)

3uf0A / C5BY10 Crystal structure of a putative NAD(p) dependent gluconate 5- dehydrogenase from beutenbergia cavernae(efi target efi-502044) with bound NADP (low occupancy)
    36% identity, 97% coverage of query (138 bits)

gdh / P12310 glcDH (EC 1.1.1.47) from Bacillus subtilis (strain 168) (see 6 papers)
    33% identity, 98% coverage of query (138 bits)

lxr1 / Q8NK50 D-mannitol 2-dehydrogenase (EC 1.1.1.67) from Hypocrea jecorina (see 3 papers)
NMTDH_HYPJR / Q8NK50 NADP-dependent mannitol dehydrogenase; MtDH; Mannitol 2-dehydrogenase [NADP(+)]; EC 1.1.1.138 from Hypocrea jecorina (strain ATCC 56765 / BCRC 32924 / NRRL 11460 / Rut C-30) (Trichoderma reesei) (see 2 papers)
Q8NK50 L-xylulose reductase (EC 1.1.1.10) from Trichoderma reesei (see paper)
    35% identity, 99% coverage of query (138 bits)

A0A1E3M3N6 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acinetobacter baumannii (see paper)
6zzsD / A0A1E3M3N6 Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and 3-oxovalerate (see paper)
    33% identity, 97% coverage of query (138 bits)

6zzqA Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and acetoacetate
    33% identity, 97% coverage of query (138 bits)

4wecA / A0QVJ7 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
    33% identity, 97% coverage of query (136 bits)

7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
    33% identity, 98% coverage of query (136 bits)

3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
    35% identity, 99% coverage of query (135 bits)

6j7uA / D6NKF4 Crystal structure of blue fluorescent protein from metagenomic library in complex with NADPH (see paper)
    33% identity, 97% coverage of query (135 bits)

5g4lA Phloroglucinol reductase from clostridium sp. With bound NADPH (see paper)
    34% identity, 98% coverage of query (135 bits)

2dtxA Structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt) in complex with d-mannose
    32% identity, 98% coverage of query (134 bits)

2dteA / Q9HK51 Structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt) in complex with nadh (see paper)
    32% identity, 98% coverage of query (134 bits)

7krmC / A0A077GFB1 Putative fabg bound to nadh from acinetobacter baumannii
    33% identity, 97% coverage of query (134 bits)

4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
    37% identity, 96% coverage of query (134 bits)

5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    31% identity, 98% coverage of query (133 bits)

4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
    34% identity, 99% coverage of query (133 bits)

DHRS4_HUMAN / Q9BTZ2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; Short-chain dehydrogenase/reductase family member 4; EC 1.1.1.184 from Homo sapiens (Human) (see 7 papers)
Q9BTZ2 NADP-retinol dehydrogenase (EC 1.1.1.300) from Homo sapiens (see paper)
    34% identity, 98% coverage of query (132 bits)

4qecA / I6ZQW6 Elxo with NADP bound (see paper)
    31% identity, 95% coverage of query (132 bits)

3o4rA / Q9BTZ2 Crystal structure of human dehydrogenase/reductase (sdr family) member 4 (dhrs4)
    34% identity, 96% coverage of query (132 bits)

1zemA / Q8GR61 Crystal structure of NAD+-bound xylitol dehydrogenase (see paper)
    34% identity, 96% coverage of query (132 bits)

6qheA / A0A545BBS8 Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
    32% identity, 99% coverage of query (131 bits)

6d9yB / B2JLJ0 Crystal structure of a short chain dehydrogenase/reductase sdr from burkholderia phymatum with partially occupied NAD
    35% identity, 98% coverage of query (130 bits)

7krgF / P0C0Y5 Crystal structure of mannitol dehydrogenase (chmdh) from cladosporium herbarum in complex with NADP+ and na (see paper)
    33% identity, 99% coverage of query (130 bits)

3gdfA Crystal structure of the NADP-dependent mannitol dehydrogenase from cladosporium herbarum.
    33% identity, 99% coverage of query (130 bits)

C0IR58 aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Ralstonia sp. (see paper)
4bmsF / C0IR58 Short chain alcohol dehydrogenase from ralstonia sp. Dsm 6428 in complex with NADPH
    32% identity, 98% coverage of query (130 bits)

5ha5D Crystal structure of an NAD-bound oxidoreductase from brucella ovis
    36% identity, 97% coverage of query (130 bits)

9clyB / Q8E0R2 Crystal structure of the 3-ketoacyl-(acyl-carrier-protein) reductase, cylg, from streptococcus agalactiae 2603v/r
    34% identity, 95% coverage of query (129 bits)

5t2uA / A0R723 Short chain dehydrogenase/reductase family protein (see paper)
    33% identity, 97% coverage of query (129 bits)

1yxmB / Q9BY49 Crystal structure of peroxisomal trans 2-enoyl coa reductase
    31% identity, 97% coverage of query (129 bits)

2rh4A Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin
    32% identity, 95% coverage of query (128 bits)

1xr3A Actinorhodin polyketide ketoreductase with NADP and the inhibitor isoniazid bound
    32% identity, 95% coverage of query (128 bits)

1w4zA Structure of actinorhodin polyketide (actiii) reductase
    32% identity, 95% coverage of query (128 bits)

2rh4B / P16544 Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin (see paper)
    32% identity, 95% coverage of query (128 bits)

ACT3_STRCO / P16544 Putative ketoacyl reductase; EC 1.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 2 papers)
    32% identity, 95% coverage of query (128 bits)

Build an alignment

Build an alignment for WP_048081445.1 and 100 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory