Searching for up to 100 curated homologs for WP_050464367.1 NCBI__GCF_001189915.1:WP_050464367.1 (310 a.a.)
Found high-coverage hits (≥70%) to 23 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PS417_07250 2-deoxy-3-keto-D-ribonoate cleavage enzyme from Pseudomonas simiae WCS417
76% identity, 100% coverage of query (483 bits)
DOHCE_PARG4 / B1G5Y9 3,5-dioxohexanoate:acetyl-CoA acetone transferase; 3,5-dioxohexanoate cleavage enzyme; BKACE_274; EC 2.3.1.319 from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
69% identity, 100% coverage of query (441 bits)
3e49A / Q13GE9 Crystal structure of a prokaryotic domain of unknown function (duf849) with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb400 at 1.75 a resolution
66% identity, 99% coverage of query (439 bits)
3e02A / Q13I95 Crystal structure of a duf849 family protein (bxe_c0271) from burkholderia xenovorans lb400 at 1.90 a resolution
59% identity, 100% coverage of query (394 bits)
8ripA / A1B802 Beta-keto acid cleavage enzyme from paracoccus denitrificans with bound malonate and coenzyme a
62% identity, 100% coverage of query (385 bits)
8rioA Beta-keto acid cleavage enzyme from paracoccus denitrificans
62% identity, 98% coverage of query (384 bits)
H281DRAFT_00641 2-deoxy-3-keto-D-ribonate cleavage enzyme from Paraburkholderia bryophila 376MFSha3.1
57% identity, 99% coverage of query (360 bits)
3lotD / O29058 Crystal structure of protein of unknown function (np_070038.1) from archaeoglobus fulgidus at 1.89 a resolution
53% identity, 100% coverage of query (328 bits)
kce / Q8RHX2 3-keto,5-aminohexanoate cleavage enzyme subunit (EC 2.3.1.247) from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) (see 2 papers)
KCE_FUSNN / Q8RHX2 3-keto-5-aminohexanoate cleavage enzyme; EC 2.3.1.247 from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) (see 2 papers)
Q8RHX2 3-keto-5-aminohexanoate cleavage enzyme (EC 2.3.1.247) from Fusobacterium nucleatum subsp. nucleatum (see 2 papers)
37% identity, 96% coverage of query (168 bits)
KCE_CLOAI / B0VHH0 3-keto-5-aminohexanoate cleavage enzyme; EC 2.3.1.247 from Cloacimonas acidaminovorans (strain Evry) (see paper)
B0VHH0 3-keto-5-aminohexanoate cleavage enzyme (EC 2.3.1.247) from Candidatus Cloacimonas acidaminovorans (see paper)
kce / CAO80785.1 3-keto-5-aminohexanoate cleavage enzyme from Candidatus Cloacimonas acidaminovorans str. Evry (see paper)
34% identity, 95% coverage of query (156 bits)
2y7gA Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (kce) from c. Cloacamonas acidaminovorans in complex with the product acetoacetate
34% identity, 95% coverage of query (156 bits)
2y7fD Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (kce) from c. Cloacamonas acidaminovorans in complex with the substrate 3- keto-5-aminohexanoate
34% identity, 95% coverage of query (156 bits)
2y7fA Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (kce) from c. Cloacamonas acidaminovorans in complex with the substrate 3- keto-5-aminohexanoate
34% identity, 95% coverage of query (156 bits)
2y7dD / B0VHH0 Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (kce) from candidatus cloacamonas acidaminovorans (orthorombic form) (see paper)
34% identity, 95% coverage of query (155 bits)
DHCCE_RHIME / Q92NF6 3-dehydrocarnitine:acetyl-CoA trimethylamine transferase; 3-dehydrocarnitine cleavage enzyme; EC 2.3.1.317 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
33% identity, 97% coverage of query (148 bits)
Pf6N2E2_4692 dehydrocarnitine cleavage enzyme (EC 2.3.1.-) from Pseudomonas fluorescens FW300-N2E2
35% identity, 95% coverage of query (140 bits)
cdhC / Q9HTH7 3-dehydrocarnitine cleavage enzyme from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
DHCCE_PSEAE / Q9HTH7 3-dehydrocarnitine:acetyl-CoA trimethylamine transferase; 3-dehydrocarnitine cleavage enzyme; EC 2.3.1.317 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
33% identity, 96% coverage of query (137 bits)
3fa5A / A1B7S1 Crystal structure of a duf849 family protein (pden_3495) from paracoccus denitrificans pd1222 at 1.90 a resolution
30% identity, 96% coverage of query (122 bits)
3no5E / Q471D6 Crystal structure of a pfam duf849 domain containing protein (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution
31% identity, 97% coverage of query (117 bits)
3OXCE_CUPNH / Q0KAA1 3-oxoadipate:acetyl-CoA acetyltransferase; 3-oxoadipate cleavage enzyme; BKACE_378; EC 2.3.1.318 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
30% identity, 97% coverage of query (116 bits)
Build an alignment for WP_050464367.1 and 20 homologs with ≥ 30% identity
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3chvA / Q6SJB6 Crystal structure of a prokaryotic domain of unknown function (duf849) member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a resolution
28% identity, 97% coverage of query (112 bits)
5zmyA Crystal structure of a cis-epoxysuccinate hydrolase producing d(-)- tartaric acids
29% identity, 90% coverage of query (85.1 bits)
5zmuD / F1LJ99 Crystal structure of a cis-epoxysuccinate hydrolase producing d(-)- tartaric acids (see paper)
29% identity, 90% coverage of query (83.2 bits)
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Lawrence Berkeley National Laboratory