Searching for up to 100 curated homologs for WP_050465009.1 NCBI__GCF_001189915.1:WP_050465009.1 (310 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SM_b21112 L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase from Sinorhizobium meliloti 1021
    39% identity, 92% coverage of query (194 bits)

8gsrA / Q1NEI7 Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
    40% identity, 80% coverage of query (181 bits)

lra6 / Q1NEI7 2,4-didehydro-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Sphingomonas sp. (strain SKA58) (see paper)
    41% identity, 80% coverage of query (181 bits)

8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form)
    40% identity, 80% coverage of query (181 bits)

BPHYT_RS34210 2,4-diketo-3-deoxy-L-rhamnonate hydrolase (EC 3.7.1.-) from Burkholderia phytofirmans PsJN
    38% identity, 79% coverage of query (177 bits)

C785_RS20550 / A0A2E7P912 5-hydroxy-2,4-dioxopentanoate hydrolase (EC 3.7.1.26) from Herbaspirillum sp. (see paper)
    38% identity, 82% coverage of query (174 bits)

HSERO_RS06355 2,4-diketo-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Herbaspirillum seropedicae SmR1
    37% identity, 82% coverage of query (174 bits)

8skyB / O06724 Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
    41% identity, 70% coverage of query (163 bits)

YISK_BACSU / O06724 Uncharacterized protein YisK from Bacillus subtilis (strain 168) (see paper)
    41% identity, 70% coverage of query (163 bits)

8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid
    41% identity, 70% coverage of query (163 bits)

Y2993_MYCTU / I6Y276 Protein Rv2993c from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    37% identity, 82% coverage of query (159 bits)

3qdfA / B2HIH3 Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
    35% identity, 75% coverage of query (137 bits)

6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
    37% identity, 72% coverage of query (135 bits)

6v77B / A0QTY3 Crystal structure of a putative hpce protein from mycobacterium smegmatis
    34% identity, 88% coverage of query (133 bits)

4dbhA / Q8NQY2 Crystal structure of cg1458 with inhibitor (see paper)
    35% identity, 76% coverage of query (132 bits)

K0A9N9 fumarylacetoacetase (EC 3.7.1.2) from Exiguobacterium antarcticum (see paper)
    36% identity, 72% coverage of query (132 bits)

dntG / Q8VUC7 2,4-dihydroxy-5-methyl-6-oxohexa-2,4-dienoate isomerase from Burkholderia cepacia (see 2 papers)
    34% identity, 74% coverage of query (132 bits)

hbzF / Q0QFQ3 maleylpyruvate hydrolase monomer (EC 3.7.1.23) from Pseudomonas alcaligenes (see 2 papers)
HBZF_PSEAC / Q0QFQ3 Maleylpyruvate hydrolase; MPH11; EC 3.7.1.23 from Pseudomonas alcaligenes (see 3 papers)
Q0QFQ3 maleylpyruvate hydrolase (EC 3.7.1.23) from Pseudomonas alcaligenes (see 2 papers)
    32% identity, 86% coverage of query (127 bits)

3r6oA / B1MJ53 Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
    32% identity, 79% coverage of query (123 bits)

G2IPX5 maleylpyruvate hydrolase (EC 3.7.1.23) from Sphingobium sp. SYK-6 (see paper)
    33% identity, 83% coverage of query (120 bits)

A0A1R4GQY2 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Corynebacterium glutamicum (see paper)
    34% identity, 77% coverage of query (119 bits)

6j5xA / Q8NLC0 Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
    34% identity, 77% coverage of query (118 bits)

6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate
    34% identity, 77% coverage of query (118 bits)

6jvwB / G2IPX5 Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
    31% identity, 83% coverage of query (110 bits)

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Build an alignment for WP_050465009.1 and 24 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

FAH_ARATH / Q8RW90 Fumarylacetoacetase; Fumarylacetoacetate hydrolase; AtFAH; Protein SHORT-DAY SENSITIVE CELL DEATH 1; EC 3.7.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q8RW90 fumarylacetoacetase (EC 3.7.1.2) from Arabidopsis thaliana (see 3 papers)
    22% identity, 88% coverage of query (57.4 bits)

2q1dX 2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and 2,5-dioxopentanoate
    26% identity, 70% coverage of query (45.8 bits)

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