Sites on a Tree

 

Searching for up to 100 curated homologs for WP_051060823.1 NCBI__GCF_002263495.1:WP_051060823.1 (559 a.a.)

Found high-coverage hits (≥70%) to 35 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

C6L2F4 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Toxoplasma gondii (see paper)
    38% identity, 92% coverage of query (294 bits)

pgcA / P18159 α-phosphoglucomutase (EC 5.4.2.2) from Bacillus subtilis (strain 168) (see paper)
PGCA_BACSU / P18159 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
    34% identity, 92% coverage of query (286 bits)

PGM3_SCHPO / O74478 Probable phosphoribomutase; PRM; Phosphoglucomutase 3 homolog; PGM 3 homolog; EC 5.4.2.7 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    34% identity, 92% coverage of query (285 bits)

pgmA / CAB96418.1 phosphoglucomutase from Streptococcus thermophilus (see paper)
    34% identity, 96% coverage of query (281 bits)

PGM2_MOUSE / Q7TSV4 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-1; Phosphoglucomutase-2; PGM 2; EC 5.4.2.7; EC 5.4.2.2 from Mus musculus (Mouse) (see paper)
    33% identity, 98% coverage of query (275 bits)

PGM2 / Q96G03 phosphoglucomutase-2 (EC 5.4.2.2; EC 5.4.2.7) from Homo sapiens (see 2 papers)
PGM2_HUMAN / Q96G03 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-2; EC 5.4.2.7; EC 5.4.2.2 from Homo sapiens (Human) (see 2 papers)
    33% identity, 98% coverage of query (273 bits)

PGM2L_MOUSE / Q8CAA7 Glucose 1,6-bisphosphate synthase; Phosphoglucomutase-2-like 1; EC 2.7.1.106 from Mus musculus (Mouse) (see paper)
    33% identity, 95% coverage of query (268 bits)

PGM3_YEAST / Q03262 Phosphoribomutase; PRM; Phosphoglucomutase 3; PGM 3; EC 5.4.2.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
    33% identity, 93% coverage of query (267 bits)

PGM2L_HUMAN / Q6PCE3 Glucose 1,6-bisphosphate synthase; PMMLP; Phosphoglucomutase-2-like 1; EC 2.7.1.106 from Homo sapiens (Human) (see 3 papers)
    33% identity, 95% coverage of query (265 bits)

PGCA_STAA8 / Q2FVC1 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    32% identity, 93% coverage of query (247 bits)

Build an alignment

Build an alignment for WP_051060823.1 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

celB / AAA21561.1 phosphoglucomutase from Komagataeibacter xylinus (see paper)
    25% identity, 95% coverage of query (99.8 bits)

PH0923 / O58651 phosphomannose mutase (EC 5.4.2.8) from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
1wqaA / O58651 Crystal structure of pyrococcus horikoshii phosphomannomutase/phosphoglucomutase complexed with mg2+
    26% identity, 70% coverage of query (94.0 bits)

Q5X1A3 phosphoglucosamine mutase (EC 5.4.2.10) from Legionella pneumophila (see paper)
    26% identity, 85% coverage of query (86.7 bits)

M1T754 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2); phosphomannomutase (EC 5.4.2.8) from Sphingomonas sanxanigenens (see paper)
    27% identity, 73% coverage of query (79.7 bits)

Q81VN7 phosphoglucosamine mutase (EC 5.4.2.10) from Bacillus anthracis (see paper)
    25% identity, 89% coverage of query (75.9 bits)

GLMM_STRR6 / Q8DP16 Phosphoglucosamine mutase; EC 5.4.2.10 from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
    25% identity, 76% coverage of query (75.5 bits)

P74027 glucose-1,6-bisphosphate synthase from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
    25% identity, 85% coverage of query (74.3 bits)

YhbF / b3176 phosphoglucosamine mutase (EC 5.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
glmM / P31120 phosphoglucosamine mutase (EC 5.4.2.10) from Escherichia coli (strain K12) (see 9 papers)
GLMM_ECOLI / P31120 Phosphoglucosamine mutase; EC 5.4.2.10 from Escherichia coli (strain K12) (see 2 papers)
glmM phosphoglucosamine mutase; EC 5.4.2.10 from Escherichia coli K12 (see 6 papers)
    28% identity, 85% coverage of query (73.6 bits)

7omlA Bacillus subtilis phosphoglucomutase glmm (metal bound)
    24% identity, 89% coverage of query (68.9 bits)

7ojrA / O34824 Bacillus subtilis phosphoglucomutase glmm (phosphate bound) (see paper)
    24% identity, 89% coverage of query (68.9 bits)

6nqhA Xanthomonas citri dephospho-pgm in complex with xylose-1-phosphate
    26% identity, 88% coverage of query (65.9 bits)

6np8A Xanthomonas citri phospho-pgm in complex with mannose-6-phosphate
    26% identity, 88% coverage of query (65.9 bits)

6nolA Xanthomonas citri dephospho-pgm in complex with mannose-1-phosphate
    26% identity, 88% coverage of query (65.9 bits)

6nnpA Xanthomonas citri dephospho-pgm in complex with glucose-6-phosphate
    26% identity, 88% coverage of query (65.9 bits)

6nn2A Xanthomonas citri pgm apo-phospho
    26% identity, 88% coverage of query (65.9 bits)

6n1eA Crystal structure of x. Citri phosphoglucomutase in complex with 1- methyl-glucose 6-phosphate
    26% identity, 88% coverage of query (65.9 bits)

6mnvA Crystal structure of x. Citri phosphoglucomutase in complex with ch2fg1p
    26% identity, 88% coverage of query (65.9 bits)

6mlhA Crystal structure of x. Citri phosphoglucomutase in complex with glucopyranosyl-1-methyl-phosphonic acid
    26% identity, 88% coverage of query (65.9 bits)

6mlfA Crystal structure of x. Citri phosphoglucomutase in complex with 6- fluoro glucose 1-phosphate
    26% identity, 88% coverage of query (65.9 bits)

5kl0A Crystal structure of phosphoglucomutase from xanthomonas citri citri complexed with glucose-1,6-biphosphate
    26% identity, 88% coverage of query (65.9 bits)

6mlwA Crystal structure of x. Citri phosphoglucomutase in complex with 2- fluoro mannosyl-1-methyl-phosphonic acid
    26% identity, 87% coverage of query (65.5 bits)

5bmpA Crystal structure of phosphoglucomutase from xanthomonas citri complexed with glucose-1-phosphate (see paper)
    26% identity, 87% coverage of query (65.5 bits)

3i3wA / Q5NII8 Structure of a phosphoglucosamine mutase from francisella tularensis
    22% identity, 89% coverage of query (64.3 bits)

PGM_SCHPO / O74374 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    23% identity, 74% coverage of query (60.1 bits)

4hjhA Iodide sad phased crystal structure of a phosphoglucomutase from brucella melitensis complexed with glucose-6-phosphate
    28% identity, 85% coverage of query (57.4 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory