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Searching for up to 100 curated homologs for WP_051184593.1 NCBI__GCF_000422285.1:WP_051184593.1 (223 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

IORB_METTM / P80911 Indolepyruvate oxidoreductase subunit IorB; IOR; Indolepyruvate ferredoxin oxidoreductase subunit beta; EC 1.2.7.8 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    37% identity, 88% coverage of query (121 bits)

iorB / A0A5C0XRQ6 indolepyruvate ferredoxin oxidoreductase β subunit (EC 1.2.7.8) from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see paper)
    35% identity, 87% coverage of query (115 bits)

O07836 indolepyruvate ferredoxin oxidoreductase (subunit 1/2) (EC 1.2.7.8) from Thermococcus kodakarensis (see paper)
    34% identity, 85% coverage of query (114 bits)

Q6LZB5 indolepyruvate ferredoxin oxidoreductase (subunit 1/2) (EC 1.2.7.8) from Methanococcus maripaludis (see paper)
    32% identity, 87% coverage of query (95.9 bits)

Q6M0F6 indolepyruvate ferredoxin oxidoreductase (subunit 1/2) (EC 1.2.7.8) from Methanococcus maripaludis (see paper)
    30% identity, 88% coverage of query (81.3 bits)

Build an alignment

Build an alignment for WP_051184593.1 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

porC / O27772 pyruvate synthase subunit γ (EC 1.2.7.1) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see 7 papers)
    27% identity, 87% coverage of query (57.8 bits)

PORC_METTM / P80902 Pyruvate synthase subunit PorC; Pyruvate oxidoreductase gamma chain; POR; Pyruvic-ferredoxin oxidoreductase subunit gamma; EC 1.2.7.1 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    27% identity, 87% coverage of query (57.8 bits)

KORC_METTM / P80906 2-oxoglutarate synthase subunit KorC; 2-ketoglutarate oxidoreductase gamma chain; KOR; 2-oxoglutarate-ferredoxin oxidoreductase subunit gamma; EC 1.2.7.3 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    30% identity, 86% coverage of query (57.0 bits)

P80523 pyruvate synthase (subunit 2/4) (EC 1.2.7.1) from Methanosarcina barkeri (see paper)
    27% identity, 87% coverage of query (56.6 bits)

padE / Q8L3B3 phenylglyoxylate dehydrogenase (acylating) subunit PadE (EC 1.2.1.58) from Aromatoleum evansii (see 2 papers)
PADE_AROEV / Q8L3B3 NADH-dependent phenylglyoxylate dehydrogenase subunit gamma; Phenylglyoxylate:NAD oxidoreductase; Phenylglyoxylate:acceptor oxidoreductase; EC 1.2.1.58 from Aromatoleum evansii (Azoarcus evansii) (see paper)
    28% identity, 83% coverage of query (56.6 bits)

W8CQB1 pyruvate synthase (subunit 2/4) (EC 1.2.7.1); pyruvate decarboxylase (subunit 2/4) (EC 4.1.1.1) from Thermococcus guaymasensis (see paper)
    27% identity, 89% coverage of query (56.2 bits)

Psest_3517 branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate from Pseudomonas stutzeri RCH2
    28% identity, 88% coverage of query (54.7 bits)

D3DIA3 2-oxoglutarate synthase (subunit 3/5) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 2 papers)
    28% identity, 79% coverage of query (54.3 bits)

Q9P9E7 pyruvate synthase (subunit 2/5) (EC 1.2.7.1) from Methanococcus maripaludis (see paper)
    30% identity, 79% coverage of query (52.8 bits)

korA / B0R3G0 2-oxoglutarate--ferredoxin oxidoreductase α subunit (EC 1.2.7.3) from Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) (see 2 papers)
    26% identity, 87% coverage of query (51.2 bits)

salQ / B0L7F0 5-chloro-4-hydroxy-2-oxopentanoate decarboxylase (acylating) from Salinispora tropica (see paper)
    27% identity, 77% coverage of query (50.8 bits)

Q51799 pyruvate synthase (subunit 1/4) (EC 1.2.7.1) from Pyrococcus furiosus (see 2 papers)
    27% identity, 86% coverage of query (50.4 bits)

korG / Q6LXN4 2-oxoglutarate ferredoxin oxidoreductase γ subunit (EC 1.2.7.3) from Methanococcus maripaludis (strain S2 / LL) (see 2 papers)
    26% identity, 85% coverage of query (47.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory