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Searching for up to 100 curated homologs for WP_052664800.1 NCBI__GCF_000969705.1:WP_052664800.1 (293 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SSO2636 / Q97VI7 glycolaldehyde oxidoreductase medium subunit from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
    36% identity, 96% coverage of query (174 bits)

Q974U9 glyceraldehyde dehydrogenase (FAD-containing) (subunit 2/3) (EC 1.2.99.8) from Sulfurisphaera tokodaii (see paper)
    38% identity, 98% coverage of query (174 bits)

cutB / Q4J6M6 aldehyde dehydrogenase β subunit (EC 1.2.99.8) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
CUTB_SULAC / Q4J6M6 Glyceraldehyde dehydrogenase medium chain; Glyceraldehyde dehydrogenase subunit B; Glyceraldehyde dehydrogenase subunit beta; EC 1.2.99.8 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4J6M6 glyceraldehyde dehydrogenase (FAD-containing) (subunit 2/3) (EC 1.2.99.8) from Sulfolobus acidocaldarius (see paper)
    36% identity, 96% coverage of query (169 bits)

ndhA / Q59127 NdhA (EC 1.5.99.4) from Paenarthrobacter nicotinovorans (see 2 papers)
NDHM_PAENI / Q59127 Nicotine 6-hydroxylase medium subunit; Nicotine dehydrogenase medium subunit; Nicotine dehydrogenase subunit A; NDH A; EC 1.5.99.4 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see 2 papers)
Q59127 nicotine dehydrogenase (EC 1.5.99.4) from Paenarthrobacter nicotinovorans (see 2 papers)
AAK64243.1 ndhM from Paenarthrobacter nicotinovorans (see paper)
    38% identity, 96% coverage of query (164 bits)

4zohB / Q974U9 Crystal structure of glyceraldehyde oxidoreductase (see paper)
    37% identity, 97% coverage of query (164 bits)

DCMM_HYDPS / P19914 Carbon monoxide dehydrogenase medium chain; CO dehydrogenase subunit M; CO-DH M; EC 1.2.5.3 from Hydrogenophaga pseudoflava (Pseudomonas carboxydoflava) (see paper)
P19914 aerobic carbon monoxide dehydrogenase (subunit 2/3) (EC 1.2.5.3) from Hydrogenophaga pseudoflava (see 2 papers)
    40% identity, 98% coverage of query (162 bits)

kdhA / O87681 ketone dehydrogenase medium subunit (EC 1.5.99.14) from Paenarthrobacter nicotinovorans (see paper)
KDHA_PAENI / O87681 6-hydroxypseudooxynicotine dehydrogenase complex subunit alpha; Ketone dehydrogenase medium FAD subunit; EC 1.5.99.14 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see paper)
AAK64248.1 kdhM from Paenarthrobacter nicotinovorans (see paper)
kdhM / CAC37486.2 ketone dehydrogenase medium subunit from Paenarthrobacter nicotinovorans (see paper)
    36% identity, 98% coverage of query (161 bits)

7dqxE / O87681 Crystal structure of xanthine dehydrogenase family protein
    36% identity, 98% coverage of query (160 bits)

1ffuC / P19914 Carbon monoxide dehydrogenase from hydrogenophaga pseudoflava which lacks the mo-pyranopterin moiety of the molybdenum cofactor (see paper)
    41% identity, 98% coverage of query (160 bits)

DCMM_AFIC5 / P19920 Carbon monoxide dehydrogenase medium chain; CO dehydrogenase subunit M; CO-DH M; EC 1.2.5.3 from Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) (Oligotropha carboxidovorans) (see 3 papers)
P19920 aerobic carbon monoxide dehydrogenase (EC 1.2.5.3); anaerobic carbon-monoxide dehydrogenase (subunit 2/3) (EC 1.2.7.4) from Afipia carboxidovorans (see 3 papers)
    38% identity, 98% coverage of query (155 bits)

1n5wC / P19920 Crystal structure of the cu,mo-co dehydrogenase (codh); oxidized form (see paper)
    38% identity, 98% coverage of query (155 bits)

F9VNL6 glyceraldehyde dehydrogenase (FAD-containing) (subunit 2/3) (EC 1.2.99.8) from Sulfurisphaera tokodaii (see paper)
    33% identity, 97% coverage of query (146 bits)

atcB / A0A127F985 1-testosterone hydratase/dehydrogenase β subunit (EC 1.17.99.11) from Steroidobacter denitrificans (see 2 papers)
A0A127F985 3-oxo-DELTA1-steroid hydratase/dehydrogenase (subunit 2/3) (EC 1.17.99.11) from Steroidobacter denitrificans (see paper)
    36% identity, 98% coverage of query (144 bits)

D5G1Y0 anaerobic carbon-monoxide dehydrogenase (subunit 2/3) (EC 1.2.7.4) from Mycobacterium sp. (see paper)
    37% identity, 97% coverage of query (137 bits)

CDHB_PSEU3 / D7REY4 Caffeine dehydrogenase subunit beta; Caffeine dehydrogenase medium subunit; EC 1.17.5.2 from Pseudomonas sp. (strain CBB1) (see paper)
    30% identity, 98% coverage of query (123 bits)

1t3qC / P72222 Crystal structure of quinoline 2-oxidoreductase from pseudomonas putida 86 (see paper)
    33% identity, 96% coverage of query (118 bits)

P72222 quinoline 2-oxidoreductase (subunit 3/3) (EC 1.3.99.17) from Pseudomonas putida (see paper)
    33% identity, 96% coverage of query (118 bits)

Build an alignment

Build an alignment for WP_052664800.1 and 17 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

picA2 / A0A1X9WE64 picolinate 6-hydroxylase β subunit from Alcaligenes faecalis (see paper)
    29% identity, 97% coverage of query (100 bits)

XdhB / b2867 putative xanthine dehydrogenase FAD-binding subunit XdhB (EC 1.17.1.4) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
xdhB / Q46800 putative xanthine dehydrogenase FAD-binding subunit XdhB (EC 1.17.1.4) from Escherichia coli (strain K12) (see 2 papers)
Q46800 xanthine dehydrogenase (subunit 1/2) (EC 1.17.1.4) from Escherichia coli (see paper)
    28% identity, 95% coverage of query (88.6 bits)

Dshi_2958 Xanthine dehydrogenase (EC 1.17.1.4) from Dinoroseobacter shibae DFL-12
    29% identity, 98% coverage of query (81.3 bits)

hbaD / G3XCQ8 4-hydroxybenzoyl-CoA reductase HbaD subunit (EC 1.1.7.1) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) (see 7 papers)
    30% identity, 79% coverage of query (81.3 bits)

AO356_02560 Xanthine dehydrogenase (EC 1.17.1.4) from Pseudomonas fluorescens FW300-N2C3
    28% identity, 86% coverage of query (72.4 bits)

1jroA / O54050 Crystal structure of xanthine dehydrogenase from rhodobacter capsulatus (see paper)
    29% identity, 91% coverage of query (69.3 bits)

2w54A Crystal structure of xanthine dehydrogenase from rhodobacter capsulatus in complex with bound inhibitor pterin-6-aldehyde
    29% identity, 91% coverage of query (69.3 bits)

O54050 xanthine dehydrogenase (subunit 2/2) (EC 1.17.1.4); xanthine oxidase (EC 1.17.3.2) from Rhodobacter capsulatus (see 2 papers)
xdhA / CAA04469.1 xanthine dehydrogenase from Rhodobacter capsulatus (see paper)
    29% identity, 91% coverage of query (68.9 bits)

hcrB / O33820 4-hydroxybenzoyl-CoA reductase β subunit (EC 1.1.7.1) from Thauera aromatica (see paper)
HCRB_THAAR / O33820 4-hydroxybenzoyl-CoA reductase subunit beta; 4-HBCR subunit beta; EC 1.1.7.1 from Thauera aromatica (see 2 papers)
hcrB / CAA05039.1 4-Hydroxybenzoyl-CoA reductase beta-subunit from Thauera aromatica (see paper)
    25% identity, 94% coverage of query (63.9 bits)

1rm6B / O33820 Structure of 4-hydroxybenzoyl-coa reductase from thauera aromatica (see paper)
    25% identity, 94% coverage of query (63.9 bits)

PS417_20885 Xanthine dehydrogenase (EC 1.17.1.4) from Pseudomonas simiae WCS417
    27% identity, 86% coverage of query (63.5 bits)

hcrB / Q5P3F4 4-hydroxybenzoyl-CoA reductase, β subunit (EC 1.1.7.1) from Aromatoleum aromaticum (strain EbN1) (see 3 papers)
    29% identity, 74% coverage of query (63.5 bits)

XDH1 / Q8GUQ8 xanthine dehydrogenase monomer (EC 1.17.1.4) from Arabidopsis thaliana (see paper)
XDH1_ARATH / Q8GUQ8 Xanthine dehydrogenase 1; AtXDH1; EC 1.17.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
    26% identity, 80% coverage of query (53.1 bits)

Q2QB48 aldehyde oxidase (EC 1.2.3.1) from Canis lupus familiaris (see 2 papers)
    24% identity, 77% coverage of query (51.6 bits)

Q2QB50 aldehyde oxidase (EC 1.2.3.1) from Gallus gallus (see 3 papers)
    24% identity, 82% coverage of query (51.6 bits)

HXNS_EMENI / A0A1U8QNG8 Nicotinate hydroxylase hnxS; Nicotinate catabolism cluster protein hxnS; Purine hydroxylase II; PHII; Xanthine dehydrogenase II; EC 1.-.-.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 3 papers)
    24% identity, 80% coverage of query (50.8 bits)

XDH2_ARATH / F4JLI5 Xanthine dehydrogenase 2; AtXDH2; EC 1.17.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    26% identity, 85% coverage of query (49.3 bits)

AOXB_MACFA / C4NYZ3 Aldehyde oxidase 2; Aldehyde oxidase homolog 3; Azaheterocycle hydroxylase 2; EC 1.2.3.1; EC 1.17.3.- from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
    23% identity, 75% coverage of query (49.3 bits)

AOXD_CAVPO / H9TB18 Aldehyde oxidase 4; Aldehyde oxidase homolog 2; Azaheterocycle hydroxylase 4; Retinal oxidase; EC 1.2.3.1; EC 1.17.3.- from Cavia porcellus (Guinea pig) (see paper)
    24% identity, 76% coverage of query (48.9 bits)

Q2QB49 aldehyde oxidase (EC 1.2.3.1) from Gallus gallus (see 2 papers)
    24% identity, 96% coverage of query (46.6 bits)

5y6qB / Q84IX9 Crystal structure of an aldehyde oxidase from methylobacillus sp. Ky4400 (see paper)
    22% identity, 78% coverage of query (45.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory