Sites on a Tree

 

Searching for up to 100 curated homologs for WP_052667449.1 NCBI__GCF_000969705.1:WP_052667449.1 (230 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

U5LHK3 ABC-type quaternary amine transporter (subunit 2/3) (EC 7.6.2.9) from Bacillus infantis (see paper)
    42% identity, 84% coverage of query (126 bits)

TC 3.A.1.12.10 / Q87WH4 OpuC aka PSPTO4576, component of The OpuC transporter selective for glycine betaine > choline, acetylcholine, carnitine and proline betaine (contains tandem cystathionine-β-synthase (CBS) domains in the ABC component of OpuC that are required for osmoregulatory function (Chen and Beattie, 2007)) from Pseudomonas syringae pv. tomato (see paper)
    37% identity, 82% coverage of query (112 bits)

OPUBB_BACSU / Q45461 Choline transport system permease protein OpuBB from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.12.3 / Q45461 OPBB aka OpuBB aka PROW, component of Choline porter from Bacillus subtilis (see 3 papers)
    33% identity, 88% coverage of query (110 bits)

OPUCB_BACSU / O34878 Glycine betaine/carnitine/choline transport system permease protein OpuCB from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.12.4 / O34878 OPCB aka OpuCB, component of Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate from Bacillus subtilis (see 2 papers)
    34% identity, 88% coverage of query (110 bits)

OPUCB_LISM4 / G2JZ43 Carnitine transport permease protein OpuCB from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCB_LISMN / Q9KHT8 Carnitine transport permease protein OpuCB from Listeria monocytogenes (see paper)
    32% identity, 90% coverage of query (107 bits)

OPUCD_BACSU / O34742 Glycine betaine/carnitine/choline transport system permease protein OpuCD from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.12.4 / O34742 OPCD aka OpuCD, component of Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate from Bacillus subtilis (see 2 papers)
    31% identity, 91% coverage of query (99.8 bits)

EGTUB_ENTFA / Q837Z8 Probable ergothioneine transporter EgtUBC from Enterococcus faecalis (strain ATCC 700802 / V583) (see paper)
    40% identity, 81% coverage of query (98.6 bits)

OPUCD_LISM4 / G2JZ41 Carnitine transport permease protein OpuCD from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCD_LISMN / Q9KHT6 Carnitine transport permease protein OpuCD from Listeria monocytogenes (see paper)
    32% identity, 90% coverage of query (93.6 bits)

Build an alignment

Build an alignment for WP_052667449.1 and 8 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

OPUBD_BACSU / P39775 Choline transport system permease protein OpuBD from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.12.3 / P39775 OPBD aka OpuBD aka PROZ, component of Choline porter from Bacillus subtilis (see 4 papers)
    29% identity, 90% coverage of query (90.9 bits)

EGTUB_STAA3 / A0A0H2XK79 Probable ergothioneine transporter EgtUBC from Staphylococcus aureus (strain USA300) (see paper)
    33% identity, 80% coverage of query (89.7 bits)

OSMY_SALTY / Q8ZPK1 Osmoprotectant import permease protein OsmY from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.12.14 / Q8ZPK1 ABC-type transport system protein, component of OsmU (OsmVWXY) transporter for glycine betaine and choline-O-sulfate uptake. Induced by osmotic stress (0.3M NaCl) (Frossard et al., 2012). Also called OpuCA/CB1/CB2/CC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    34% identity, 88% coverage of query (89.4 bits)

OSMW_SALTY / Q8ZPK3 Osmoprotectant import permease protein OsmW from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.12.14 / Q8ZPK3 Putative binding-protein-dependent transport system, component of OsmU (OsmVWXY) transporter for glycine betaine and choline-O-sulfate uptake. Induced by osmotic stress (0.3M NaCl) (Frossard et al., 2012). Also called OpuCA/CB1/CB2/CC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    34% identity, 90% coverage of query (89.0 bits)

TC 3.A.1.12.8 / Q93A34 BilEB aka OpuBB protein, component of A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) from Listeria monocytogenes (see paper)
    36% identity, 81% coverage of query (86.3 bits)

EGTUB_LISMO / Q8Y775 Probable ergothioneine transporter EgtUBC from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) (see 2 papers)
    36% identity, 81% coverage of query (86.3 bits)

TC 3.A.1.12.11 / Q8Q043 Glycine betaine transport system, permease protein, component of The glycine betaine uptake porter, GbpABCD from Methanosarcina mazei (see paper)
    31% identity, 88% coverage of query (81.6 bits)

YehW / b2128 glycine betaine ABC transporter membrane subunit YehW from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yehW / P33359 glycine betaine ABC transporter membrane subunit YehW from Escherichia coli (strain K12) (see 2 papers)
YEHW_ECOLI / P33359 Glycine betaine uptake system permease protein YehW from Escherichia coli (strain K12) (see 3 papers)
    32% identity, 87% coverage of query (76.6 bits)

A0A077T980 ABC-type quaternary amine transporter (subunit 3/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    30% identity, 77% coverage of query (62.4 bits)

RIBX_CHLAA / A9WGD1 Riboflavin transport system permease protein RibX from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
TC 3.A.1.17.14 / A9WGD1 Riboflavin transport system permease protein RibX, component of Riboflavin uptake porter, RibXY (RibX, 168 aas and 6 TMSs; RibY, 351 aas) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
    32% identity, 78% coverage of query (57.8 bits)

SsuC / b0934 aliphatic sulfonate ABC transporter membrane subunit (EC 7.6.2.14) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
SsuC / P75851 aliphatic sulfonate ABC transporter membrane subunit (EC 7.6.2.14) from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.17.10 / P75851 Putative aliphatic sulfonates transport permease protein SsuC, component of Aliphatic sulfonate (alkanesulfonate) import permease, SsuABC (YcbOEM) and is regluated by the transcriptional activator, Cbl from Escherichia coli (strain K12)
    28% identity, 71% coverage of query (55.5 bits)

OPUAB_BACSU / P46921 Glycine betaine transport system permease protein OpuAB from Bacillus subtilis (strain 168) (see 2 papers)
P46921 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see 2 papers)
TC 3.A.1.12.2 / P46921 OPAB aka OpuAB, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis (see 3 papers)
    26% identity, 76% coverage of query (53.1 bits)

NRTB_SYNE7 / P38044 Nitrate import permease protein NrtB from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
TC 3.A.1.16.1 / P38044 NrtB, component of Four component nitrate/nitrite porter (see paper)
    24% identity, 93% coverage of query (48.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory