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Searching for up to 100 curated homologs for WP_053768090.1 NCBI__GCF_001280255.1:WP_053768090.1 (424 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

2e7uA / Q5SJS4 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from thermus thermophilus hb8
    88% identity, 100% coverage of query (743 bits)

3bs8A / P30949 Crystal structure of glutamate 1-semialdehyde aminotransferase complexed with pyridoxamine-5'-phosphate from bacillus subtilis (see paper)
    54% identity, 98% coverage of query (454 bits)

P30949 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Bacillus subtilis (see paper)
hemL / AAA22515.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus subtilis (see 2 papers)
    54% identity, 98% coverage of query (453 bits)

2gsaB Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
    54% identity, 98% coverage of query (451 bits)

2gsaA Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
    54% identity, 98% coverage of query (451 bits)

3fq7A / P24630 Gabaculine complex of gsam (see paper)
    53% identity, 98% coverage of query (450 bits)

3usfA Crystal structure of dava-4
    53% identity, 98% coverage of query (450 bits)

2hp2A Inter-subunit signaling in gsam
    53% identity, 98% coverage of query (450 bits)

2hp1A Inter-subunit signaling in gsam
    53% identity, 98% coverage of query (450 bits)

2hozA Inter-subunit signaling in gsam
    53% identity, 98% coverage of query (450 bits)

3fqaA Gabaculien complex of gabaculine resistant gsam version
    53% identity, 98% coverage of query (449 bits)

P24630 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Synechococcus sp. (see 2 papers)
    53% identity, 98% coverage of query (446 bits)

5i92F / P48247 Crystal structure of glutamate-1-semialdehyde 2,1- aminomutase (gsa) from pseudomonas aeruginosa
    54% identity, 99% coverage of query (446 bits)

Gsa / b0154 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
hemL / P23893 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli (strain K12) (see 19 papers)
GSA_ECOLI / P23893 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Escherichia coli (strain K12) (see 3 papers)
    53% identity, 98% coverage of query (442 bits)

hemL / P0CL07 glutamate-1-semialdehyde 2,1-aminomutase subunit (EC 5.4.3.8) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    53% identity, 98% coverage of query (441 bits)

GSA1 / P42799 glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
GSA1_ARATH / P42799 Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic; AtGSA1; GSA 1; Glutamate-1-semialdehyde aminotransferase 1; GSA-AT 1; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
P42799 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
    52% identity, 99% coverage of query (437 bits)

5hdmA / P42799 Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase (see paper)
    52% identity, 99% coverage of query (436 bits)

5hdmB Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase
    52% identity, 99% coverage of query (436 bits)

6w80A / B2FT35 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from stenotrophomonas maltophilia k279a in complex with plp
    53% identity, 98% coverage of query (434 bits)

GSA2_ARATH / Q42522 Glutamate-1-semialdehyde 2,1-aminomutase 2, chloroplastic; GSA 2; Glutamate-1-semialdehyde aminotransferase 2; GSA-AT 2; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    52% identity, 99% coverage of query (432 bits)

hemL / CAD48149.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus megaterium (see paper)
    52% identity, 99% coverage of query (430 bits)

3k28A / Q81LD0 Crystal structure of a glutamate-1-semialdehyde aminotransferase from bacillus anthracis with bound pyridoxal 5'phosphate
    52% identity, 96% coverage of query (422 bits)

3usfB / Q31QJ2 Crystal structure of dava-4
    50% identity, 98% coverage of query (409 bits)

2hp1B Inter-subunit signaling in gsam
    49% identity, 98% coverage of query (405 bits)

hemL / BAA21914.1 glutamate 1-semialdehyde 2,1-aminomutase from Propionibacterium freudenreichii (see 2 papers)
    49% identity, 99% coverage of query (379 bits)

Q8NT73 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Corynebacterium glutamicum (see paper)
    48% identity, 98% coverage of query (369 bits)

GSA_SACS2 / Q980U5 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q980U5 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Saccharolobus solfataricus (see paper)
    46% identity, 98% coverage of query (363 bits)

2zsmA / Q9Y9I9 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from aeropyrum pernix, hexagonal form
    49% identity, 99% coverage of query (361 bits)

2cfbA / Q8DLK8 Glutamate-1-semialdehyde 2,1-aminomutase from thermosynechococcus elongatus (see paper)
    47% identity, 89% coverage of query (344 bits)

4zm4B / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
    40% identity, 96% coverage of query (250 bits)

4zm4D / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
    40% identity, 94% coverage of query (234 bits)

BFAT_VARPD / H8WR05 Beta-phenylalanine transaminase; Aromatic beta-amino acid aminotransferase; Beta-phenylalanine aminotransferase; VpAT; EC 2.6.1.- from Variovorax paradoxus (see paper)
H8WR05 tyrosine transaminase (EC 2.6.1.5) from Variovorax paradoxus (see paper)
    37% identity, 99% coverage of query (229 bits)

4ao9A / H8WR05 Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from variovorax paradoxus (see paper)
    38% identity, 94% coverage of query (229 bits)

4aoaA Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from variovorax paradoxus
    37% identity, 99% coverage of query (229 bits)

D1C218 beta-alanine-pyruvate transaminase (EC 2.6.1.18) from Sphaerobacter thermophilus (see paper)
    35% identity, 98% coverage of query (225 bits)

6k8hB / D1C218 Crystal structure of an omega-transaminase from sphaerobacter thermophilus (see paper)
    35% identity, 98% coverage of query (224 bits)

2ykuA / A3EYF7 Structural determinants of the beta-selectivity of a bacterial aminotransferase (see paper)
    35% identity, 96% coverage of query (218 bits)

2ykyA Structural determinants of the beta-selectivity of a bacterial aminotransferase
    35% identity, 96% coverage of query (218 bits)

2ykxA Structural determinants of the beta-selectivity of a bacterial aminotransferase
    35% identity, 96% coverage of query (218 bits)

2ykvA Structural determinants of the beta-selectivity of a bacterial aminotransferase
    35% identity, 96% coverage of query (218 bits)

4ao4A Structural determinants of the beta-selectivity of a bacterial aminotransferase
    35% identity, 96% coverage of query (218 bits)

MYCA_BACIU / Q9R9J1 Mycosubtilin synthase subunit A; EC 2.3.1.- from Bacillus subtilis (see paper)
    35% identity, 90% coverage of query (198 bits)

6ssdA Transaminase with plp bound (see paper)
    33% identity, 99% coverage of query (198 bits)

6ssgA Transaminase with dcs bound
    33% identity, 99% coverage of query (198 bits)

6ssfA Transaminase with lcs bound
    33% identity, 99% coverage of query (198 bits)

6sseA Transaminase with pmp bound
    33% identity, 99% coverage of query (198 bits)

6kfuA / Q9R9J1 A acp-amt fusion protein of hybrid polyketide/non-ribosomal peptide synthetase
    36% identity, 90% coverage of query (196 bits)

6kfrA Amino-transferase (amt) domain - arg complex of hybrid polyketide/non- ribosomal peptide synthetase
    36% identity, 90% coverage of query (196 bits)

KAT_CLOAI / B0VH76 3-aminobutyryl-CoA aminotransferase; HemL-like protein; EC 2.6.1.111 from Cloacimonas acidaminovorans (strain Evry) (see paper)
B0VH76 3-aminobutanoyl-CoA transaminase (EC 2.6.1.111) from Candidatus Cloacimonas acidaminovorans (see paper)
    30% identity, 99% coverage of query (193 bits)

bmyA / CAE11250.1 BmyA protein from Bacillus amyloliquefaciens (see paper)
    35% identity, 90% coverage of query (193 bits)

dpgA / Q6VY99 D-phenylglycine aminotransferase monomer (EC 2.6.1.72) from Stutzerimonas stutzeri (see 7 papers)
Q6VY99 D-4-hydroxyphenylglycine transaminase (EC 2.6.1.72) from Pseudomonas stutzeri (see 2 papers)
    37% identity, 80% coverage of query (181 bits)

davT / Q9I6M4 5-aminovalerate aminotransferase (EC 2.6.1.48) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
DAVT_PSEAE / Q9I6M4 5-aminovalerate aminotransferase DavT; 5-aminovalerate transaminase; Delta-aminovalerate aminotransferase; EC 2.6.1.48 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I6M4 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas aeruginosa (see paper)
    35% identity, 79% coverage of query (168 bits)

mxcL / Q9F631 myxocheline aldehyde aminotransferase from Stigmatella aurantiaca (see 2 papers)
    31% identity, 97% coverage of query (163 bits)

gdnH / K4JEW9 guadinomine polyketide synthase module 4 from Streptomyces sp. K01-0509 (see paper)
    33% identity, 91% coverage of query (160 bits)

Build an alignment

Build an alignment for WP_053768090.1 and 54 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

YC7B_SCHPO / O94492 Uncharacterized aminotransferase C417.11c; EC 2.6.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    29% identity, 92% coverage of query (158 bits)

Q9HWU0 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Pseudomonas aeruginosa (see paper)
    31% identity, 93% coverage of query (157 bits)

5yktA / Q9HWU0 Crystal structure of a glutamate-1-semialdehyde-aminomutase (k286a) from pseudomonas aeruginosa pao1 in complex with pmp (see paper)
    31% identity, 93% coverage of query (155 bits)

6hbvA / D2D3B2 Structure of plp internal aldimine form of sphingopyxis sp. Mta144 fumi protein
    29% identity, 98% coverage of query (145 bits)

fumI / D2D3B2 aminopentol aminotransferase from Sphingopyxis macrogoltabida (see paper)
FUMI_SPHMC / D2D3B2 Aminopentol aminotransferase; EC 2.6.1.- from Sphingopyxis macrogoltabida (Sphingomonas macrogoltabidus) (see 2 papers)
    29% identity, 98% coverage of query (145 bits)

Pf6N2E2_4013 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas fluorescens FW300-N2E2
    33% identity, 77% coverage of query (144 bits)

gabT / Q4KKA1 4-aminobutyrate transaminase subunit (EC 2.6.1.19) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    33% identity, 77% coverage of query (142 bits)

DAVT_PSEPK / Q88RB9 5-aminovalerate aminotransferase DavT; 5-aminovalerate transaminase; Delta-aminovalerate aminotransferase; EC 2.6.1.48 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
Q88RB9 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas putida (see 2 papers)
    34% identity, 77% coverage of query (142 bits)

δ-OAT / Q9FNK4 ornithine-δ-aminotransferase (EC 2.6.1.13) from Arabidopsis thaliana (see 2 papers)
OAT_ARATH / Q9FNK4 Ornithine aminotransferase, mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9FNK4 ornithine aminotransferase (EC 2.6.1.13) from Arabidopsis thaliana (see paper)
    30% identity, 75% coverage of query (142 bits)

2eh6A / O66442 Crystal structure of acetylornithine aminotransferase from aquifex aeolicus vf5
    35% identity, 72% coverage of query (140 bits)

AO353_11510 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas fluorescens FW300-N2E3
    32% identity, 77% coverage of query (140 bits)

hpnO / B3QHB5 aminobacteriohopanetriol synthase from Rhodopseudomonas palustris (strain TIE-1) (see paper)
    34% identity, 75% coverage of query (140 bits)

O66442 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Aquifex aeolicus (strain VF5)
    35% identity, 72% coverage of query (140 bits)

6io1B / B9L0K9 Crystal structure of a novel thermostable (s)-enantioselective omega- transaminase from thermomicrobium roseum (see paper)
    35% identity, 73% coverage of query (134 bits)

7lleA Crystal structure of genb4 in complex with plp
    32% identity, 78% coverage of query (132 bits)

7lldA / Q6QVT7 Crystal structure of genb4 in complex with external aldimine of plp- sisomicin
    32% identity, 78% coverage of query (132 bits)

7lldB Crystal structure of genb4 in complex with external aldimine of plp- sisomicin
    32% identity, 80% coverage of query (132 bits)

1szkA The structure of gamma-aminobutyrate aminotransferase mutant: e211s
    31% identity, 85% coverage of query (131 bits)

GabT / b2662 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655 (see 29 papers)
gabT / P22256 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli (strain K12) (see 28 papers)
GABT_ECOLI / P22256 4-aminobutyrate aminotransferase GabT; 5-aminovalerate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT; EC 2.6.1.19; EC 2.6.1.48 from Escherichia coli (strain K12) (see 6 papers)
    31% identity, 85% coverage of query (131 bits)

1sffA Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate
    31% identity, 85% coverage of query (131 bits)

1sf2A / P22256 Structure of e. Coli gamma-aminobutyrate aminotransferase (see paper)
    31% identity, 85% coverage of query (131 bits)

A0QYS9 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    36% identity, 73% coverage of query (125 bits)

GoaG / b1302 4-aminobutyrate aminotransferase PuuE (EC 2.6.1.19; EC 2.6.1.48) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
puuE / P50457 4-aminobutyrate aminotransferase PuuE (EC 2.6.1.19; EC 2.6.1.48) from Escherichia coli (strain K12) (see 11 papers)
PUUE_ECOLI / P50457 4-aminobutyrate aminotransferase PuuE; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; EC 2.6.1.19 from Escherichia coli (strain K12) (see 2 papers)
puuE / BAD88710.1 gamma-aminobutyrate aminotransferase from Escherichia coli K-12 (see paper)
    31% identity, 76% coverage of query (121 bits)

5e3kA Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with (s)-4-amino-5-fluoropentanoic acid
    32% identity, 72% coverage of query (120 bits)

5e5iA Structure of the ornithine aminotransferase from toxoplasma gondii in complex with inactivator
    32% identity, 72% coverage of query (120 bits)

5dj9A Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with gabaculine
    32% identity, 72% coverage of query (120 bits)

5eqcA / S8EY38 Structure of the ornithine aminotransferase from toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of plp at the protein active site
    32% identity, 72% coverage of query (120 bits)

5e3kB Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with (s)-4-amino-5-fluoropentanoic acid
    32% identity, 72% coverage of query (120 bits)

2ordA / Q9X2A5 Crystal structure of acetylornithine aminotransferase (ec 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution
    29% identity, 78% coverage of query (119 bits)

Q9X2A5 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
    29% identity, 78% coverage of query (119 bits)

OAT_PLAF7 / Q6LFH8 Ornithine aminotransferase; PfOAT; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Plasmodium falciparum (isolate 3D7) (see 2 papers)
Q6LFH8 ornithine aminotransferase (EC 2.6.1.13) from Plasmodium falciparum (see 2 papers)
    27% identity, 85% coverage of query (119 bits)

7lm0A / Q2MG50 Crystal structure of genb3 in complex with plp
    31% identity, 90% coverage of query (119 bits)

1zobA Crystal structure of dialkylglycine decarboxylases bound with calcium ion
    32% identity, 74% coverage of query (116 bits)

1zc9A The crystal structure of dialkylglycine decarboxylase complex with pyridoxamine 5-phosphate
    32% identity, 74% coverage of query (116 bits)

1m0qA Structure of dialkylglycine decarboxylase complexed with s-1- aminoethanephosphonate
    32% identity, 74% coverage of query (116 bits)

1m0pA Structure of dialkylglycine decarboxylase complexed with 1-amino-1- phenylethanephosphonate
    32% identity, 74% coverage of query (116 bits)

1m0oA Structure of dialkylglycine decarboxylase complexed with 1-amino-1- methylpropanephosphonate
    32% identity, 74% coverage of query (116 bits)

1m0nA Structure of dialkylglycine decarboxylase complexed with 1- aminocyclopentanephosphonate
    32% identity, 74% coverage of query (116 bits)

1dgdA An alkali metal ion size-dependent switch in the active site structure of dialkylglycine decarboxylase
    32% identity, 74% coverage of query (116 bits)

1d7vA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with nma
    32% identity, 74% coverage of query (116 bits)

1d7uA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with lcs
    32% identity, 74% coverage of query (116 bits)

1d7sA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with dcs
    32% identity, 74% coverage of query (116 bits)

1d7rA / P16932 Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with 5pa (see paper)
    32% identity, 74% coverage of query (116 bits)

2eo5A / F9VN77 Crystal structure of 4-aminobutyrate aminotransferase from sulfolobus tokodaii strain7
    30% identity, 82% coverage of query (115 bits)

6j2vA / Q8NT35 Gaba aminotransferase from corynebacterium glutamicum (see paper)
    31% identity, 72% coverage of query (115 bits)

ASRAC_PYRHO / O58478 Alanine/serine racemase; ASR; Ala/Ser racemase; EC 5.1.1.-; EC 5.1.1.1 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
    31% identity, 72% coverage of query (113 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory