Searching for up to 100 curated homologs for WP_053938584.1 NCBI__GCF_001294205.1:WP_053938584.1 (257 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DEOC_SALTY / Q8ZJV8 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    58% identity, 98% coverage of query (261 bits)

Q7WT44 deoxyribose-phosphate aldolase (EC 4.1.2.4) from Klebsiella pneumoniae (see paper)
    58% identity, 97% coverage of query (259 bits)

Tlr / b4381 deoxyribose-phosphate aldolase (EC 4.1.2.4) from Escherichia coli K-12 substr. MG1655 (see 16 papers)
deoC / P0A6L0 deoxyribose-phosphate aldolase (EC 4.1.2.4) from Escherichia coli (strain K12) (see 14 papers)
DEOC_ECOLI / P0A6L0 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Escherichia coli (strain K12) (see 4 papers)
deoC / RF|NP_418798 phosphodeoxyriboaldolase from Escherichia coli K12 (see paper)
    59% identity, 98% coverage of query (259 bits)

5el1A Crystal structure of deoxyribose-phosphate aldolase from escherichia coli (k58e-y96w mutant) after acetaldehyde treatment
    60% identity, 95% coverage of query (256 bits)

5ekyA Crystal structure of deoxyribose-phosphate aldolase from escherichia coli (k58e-y96w mutant)
    60% identity, 95% coverage of query (256 bits)

1jcjA / P0A6L0 Observation of covalent intermediates in an enzyme mechanism at atomic resolution (see paper)
    59% identity, 96% coverage of query (255 bits)

6z9iB Escherichia coli d-2-deoxyribose-5-phosphate aldolase - n21k mutant complex with reaction products
    59% identity, 95% coverage of query (254 bits)

7p76A Re-engineered 2-deoxy-d-ribose-5-phosphate aldolase catalysing asymmetric michael addition reactions, schiff base complex with cinnamaldehyde
    57% identity, 94% coverage of query (250 bits)

8forA Crystal structure of kemp eliminase ke70-core with bound transition state analogue
    53% identity, 89% coverage of query (209 bits)

3q2dA Optimization of the in silico designed kemp eliminase ke70 by computational design and directed evolution
    52% identity, 89% coverage of query (201 bits)

DEOC_HUMAN / Q9Y315 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Homo sapiens (Human) (see paper)
Q9Y315 deoxyribose-phosphate aldolase (EC 4.1.2.4) from Homo sapiens (see paper)
    37% identity, 92% coverage of query (148 bits)

A0A125YLW2 deoxyribose-phosphate aldolase (EC 4.1.2.4) from Toxoplasma gondii (see paper)
    39% identity, 90% coverage of query (135 bits)

D5AHU8 deoxyribose-phosphate aldolase (EC 4.1.2.4) from Streptococcus suis (see paper)
    37% identity, 74% coverage of query (90.9 bits)

Q9AIP7 deoxyribose-phosphate aldolase (EC 4.1.2.4) from Streptococcus mutans (see paper)
    35% identity, 79% coverage of query (85.1 bits)

DEOC_BACSU / P39121 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Bacillus subtilis (strain 168) (see paper)
    37% identity, 75% coverage of query (81.6 bits)

C7E719 deoxyribose-phosphate aldolase (EC 4.1.2.4) from Paenibacillus sp. (see paper)
    36% identity, 75% coverage of query (77.8 bits)

Build an alignment

Build an alignment for WP_053938584.1 and 16 homologs with ≥ 30% identity

Or download the sequences

Additional hits (identity < 30%)

DPA_TOXGO / A0A7J6KBZ0 Divergent deoxyribose-phosphate aldolase-like protein; TgDPA; Divergent 2-deoxyribose 5-phosphate aldolase-like protein; Divergent dR5P aldolase-like protein from Toxoplasma gondii (see 3 papers)
    26% identity, 89% coverage of query (71.6 bits)

3ngjD / C4M5C6 Crystal structure of a putative deoxyribose-phosphate aldolase from entamoeba histolytica
    32% identity, 81% coverage of query (69.7 bits)

DEOC_PYRAE / Q8ZXK7 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2) (see paper)
    32% identity, 87% coverage of query (63.9 bits)

DEOC_AERPE / Q9Y948 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (see paper)
    29% identity, 81% coverage of query (50.4 bits)

Or start over