Searching for up to 100 curated homologs for WP_057507870.1 NCBI__GCF_001431535.1:WP_057507870.1 (375 a.a.)
Found high-coverage hits (≥70%) to 38 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
dapE / CAA08876.1 DapE from Bordetella pertussis (see paper)
57% identity, 99% coverage of query (430 bits)
DAPE_NEIMB / Q9JYL2 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Neisseria meningitidis serogroup B (strain MC58) (see paper)
Q9JYL2 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Neisseria meningitidis (see paper)
55% identity, 99% coverage of query (427 bits)
4o23A / Q9JYL2 Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
55% identity, 99% coverage of query (427 bits)
7t1qA / A3M8H2 Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
56% identity, 96% coverage of query (425 bits)
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril
55% identity, 99% coverage of query (425 bits)
dapE / P44514 N-succinyl-L,L-diaminopimelate desuccinylase subunit (EC 3.5.1.18) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
DAPE_HAEIN / P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 7 papers)
P44514 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Haemophilus influenzae (see 3 papers)
51% identity, 99% coverage of query (414 bits)
5vo3A / P44514 Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
51% identity, 99% coverage of query (414 bits)
DAPE_SALTY / Q8ZN75 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; Aspartyl peptidase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
52% identity, 99% coverage of query (399 bits)
7lgpB / P0AED8 Dape enzyme from shigella flexneri
52% identity, 99% coverage of query (397 bits)
MsgB / b2472 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
dapE / P0AED7 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Escherichia coli (strain K12) (see paper)
DAPE_ECOLI / P0AED7 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Escherichia coli (strain K12) (see paper)
dapE / RF|NP_416967 succinyl-diaminopimelate desuccinylase; EC 3.5.1.18 from Escherichia coli K12 (see 7 papers)
52% identity, 99% coverage of query (397 bits)
DAPE_VIBCH / Q9KQ52 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q9KQ52 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Vibrio cholerae (see paper)
52% identity, 99% coverage of query (382 bits)
DAPE_HELPY / O25002 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
O25002 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Helicobacter pylori (see paper)
36% identity, 98% coverage of query (236 bits)
Build an alignment for WP_057507870.1 and 12 homologs with ≥ 30% identity
Or download the sequences
argE / CAB95019.1 acetylornithinase (n2-acetyl-l-ornithine amidohydrolase) from Moritella abyssi (see paper)
29% identity, 92% coverage of query (96.7 bits)
Q92Y75 acetylornithine deacetylase (EC 3.5.1.16) from Sinorhizobium meliloti (see paper)
31% identity, 88% coverage of query (94.4 bits)
7uoiA / A0A1S8KJG1 Crystallographic structure of dape from enterococcus faecium
27% identity, 87% coverage of query (90.9 bits)
BT3549 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Bacteroides thetaiotaomicron VPI-5482
25% identity, 71% coverage of query (74.3 bits)
DAPE_MYCS2 / A0R2G4 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
29% identity, 94% coverage of query (70.9 bits)
Echvi_3851 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Echinicola vietnamensis KMM 6221, DSM 17526
26% identity, 72% coverage of query (68.2 bits)
Q59284 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Corynebacterium glutamicum (see paper)
23% identity, 83% coverage of query (67.8 bits)
N515DRAFT_3767 N-acetylcitrulline deacetylase (EC 3.5.1.-) from Dyella japonica UNC79MFTsu3.2
26% identity, 91% coverage of query (65.1 bits)
FAPD_BACSU / O31724 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase; Formylaminopyrimidine deformylase; Amidohydrolase YlmB; EC 3.5.1.- from Bacillus subtilis (strain 168) (see paper)
24% identity, 77% coverage of query (65.1 bits)
CA265_RS18500 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Pedobacter sp. GW460-11-11-14-LB5
23% identity, 73% coverage of query (63.2 bits)
ACY1_MOUSE / Q99JW2 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Mus musculus (Mouse) (see 2 papers)
Q99JW2 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Mus musculus (see 2 papers)
22% identity, 95% coverage of query (62.8 bits)
G8EJ32 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Heliothis virescens (see paper)
23% identity, 86% coverage of query (60.8 bits)
DUG2 / P38149 Deficient in Utilization of Glutathione from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
DUG2_YEAST / P38149 Probable di- and tripeptidase DUG2; Deficient in utilization of glutathione protein 2; GSH degradosomal complex subunit DUG2; EC 3.4.-.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
22% identity, 85% coverage of query (60.1 bits)
Q6AYS7 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Rattus norvegicus (see 2 papers)
23% identity, 95% coverage of query (60.1 bits)
ACY1 / Q03154 aminoacylase 1 monomer (EC 3.5.1.14) from Homo sapiens (see 7 papers)
ACY1_HUMAN / Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 5 papers)
Q03154 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Homo sapiens (see 4 papers)
24% identity, 83% coverage of query (59.7 bits)
ACY1B_RAT / Q6PTT0 Aminoacylase-1B; ACY-1B; ACY IB; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Rattus norvegicus (Rat) (see paper)
23% identity, 83% coverage of query (58.2 bits)
C9K2Z6 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Streptomyces mobaraensis (see paper)
25% identity, 84% coverage of query (57.4 bits)
P9WHS9 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Mycobacterium tuberculosis (see 2 papers)
27% identity, 98% coverage of query (57.0 bits)
CNDP2_HUMAN / Q96KP4 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase; EC 3.4.13.18 from Homo sapiens (Human) (see 5 papers)
Q96KP4 cytosol nonspecific dipeptidase (EC 3.4.13.18) from Homo sapiens (see 2 papers)
24% identity, 70% coverage of query (54.3 bits)
P37111 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Sus scrofa (see 6 papers)
22% identity, 95% coverage of query (52.8 bits)
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig)
22% identity, 95% coverage of query (52.8 bits)
1cg2A / P06621 Carboxypeptidase g2 (see paper)
26% identity, 83% coverage of query (52.4 bits)
CBPG_PSES6 / P06621 Carboxypeptidase G2; CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase; EC 3.4.17.11 from Pseudomonas sp. (strain RS-16) (see paper)
P06621 glutamate carboxypeptidase (EC 3.4.17.11) from Pseudomonas sp. (see 2 papers)
cpg / AAA62842.1 carboxypeptidase G2 precursor from Variovorax paradoxus (see 2 papers)
26% identity, 83% coverage of query (52.4 bits)
7m6uB / P06621 Crystal structure of a circular permutation and computationally designed pro-enzyme of carboxypeptidase g2 (see paper)
27% identity, 78% coverage of query (51.6 bits)
5xoyA / Q8VUS5 Crystal structure of lysk from thermus thermophilus in complex with lysine (see paper)
27% identity, 91% coverage of query (49.7 bits)
argE / Q8P8J5 acetylcitrulline deacetylase subunit (EC 3.5.1.16) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
ACDAS_XANCP / Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 3 papers)
26% identity, 91% coverage of query (46.2 bits)
Or start over
Lawrence Berkeley National Laboratory