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Searching for up to 100 curated homologs for WP_058929521.1 NCBI__GCF_001484605.1:WP_058929521.1 (740 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ACCA1_MYCTU / P9WPQ3 Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit; EC 6.3.4.14 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
CAA79609.1 biotin carboxyl carrier protein from Mycobacterium tuberculosis (see paper)
    54% identity, 93% coverage of query (651 bits)

MCCA_ORYSJ / Q2QMG2 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    44% identity, 93% coverage of query (494 bits)

atuF / Q9HZV6 cis-geranyl-CoA carboxylase α-subunit (EC 6.4.1.5) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    45% identity, 93% coverage of query (493 bits)

Sama_1359 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Shewanella amazonensis SB2B
    43% identity, 91% coverage of query (480 bits)

MCCA_ARATH / Q42523 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q42523 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Arabidopsis thaliana (see 2 papers)
    39% identity, 94% coverage of query (471 bits)

SM_b21124 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Sinorhizobium meliloti 1021
    45% identity, 93% coverage of query (468 bits)

MCCC1 / Q96RQ3 3-methylcrotonyl-CoA carboxylase α subunit (EC 6.4.1.4) from Homo sapiens (see 4 papers)
MCCA_HUMAN / Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Homo sapiens (Human) (see 15 papers)
    40% identity, 91% coverage of query (467 bits)

MCCA_MOUSE / Q99MR8 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Mus musculus (Mouse) (see paper)
    40% identity, 90% coverage of query (455 bits)

Dsui_0516 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dechlorosoma suillum PS
    41% identity, 93% coverage of query (452 bits)

7ybuA / P05165 Human propionyl-coenzyme a carboxylase
    41% identity, 92% coverage of query (438 bits)

PCCA_RUEPO / Q5LUF3 Propionyl-CoA carboxylase alpha chain; EC 6.4.1.3 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
Q5LUF3 propionyl-CoA carboxylase (EC 6.4.1.3) from Ruegeria pomeroyi (see paper)
    40% identity, 93% coverage of query (437 bits)

8rthA / Q57YQ4 Trypanosoma brucei 3-methylcrotonyl-coa carboxylase (see paper)
    39% identity, 93% coverage of query (437 bits)

PCCA / P05165 propionyl-CoA carboxylase α chain, mitochondrial (EC 6.4.1.3) from Homo sapiens (see 4 papers)
PCCA_HUMAN / P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Homo sapiens (Human) (see 11 papers)
P05165 propionyl-CoA carboxylase (subunit 1/2) (EC 6.4.1.3) from Homo sapiens (see paper)
    41% identity, 92% coverage of query (436 bits)

Pf1N1B4_3984 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N1B4
    42% identity, 91% coverage of query (436 bits)

PCCA_PIG / P0DTA4 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Sus scrofa (Pig) (see paper)
    41% identity, 92% coverage of query (435 bits)

8j78I / Q96RQ3 Human 3-methylcrotonyl-coa carboxylase in bccp-h2 state
    39% identity, 90% coverage of query (429 bits)

liuD / Q9I299 methylcrotonyl-CoA carboxylase α-subunit (EC 6.4.1.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I299 methylcrotonoyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.4) from Pseudomonas aeruginosa (see 3 papers)
    43% identity, 90% coverage of query (428 bits)

3n6rG / Q5LUF3 Crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) (see paper)
    40% identity, 93% coverage of query (420 bits)

PCCA_CAEEL / Q19842 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Caenorhabditis elegans (see paper)
Q19842 propionyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.3) from Caenorhabditis elegans (see paper)
    38% identity, 94% coverage of query (417 bits)

PCCA_HALMT / I3R7G3 Propionyl-CoA carboxylase, biotin carboxylase and biotin-carboxyl carrier subunit; PCC; EC 6.4.1.3; EC 6.3.4.14 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
I3R7G3 propionyl-CoA carboxylase (subunit 3/3) (EC 6.4.1.3) from Haloferax mediterranei (see paper)
    39% identity, 89% coverage of query (412 bits)

3n6rA / Q5LUF3 Crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) (see paper)
    35% identity, 93% coverage of query (317 bits)

Build an alignment

Build an alignment for WP_058929521.1 and 21 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

ACC1 / Q13085 acetyl-CoA carboxylase 1 (EC 2.1.3.15; EC 6.4.1.2; EC 6.3.4.14) from Homo sapiens (see 6 papers)
ACACA_HUMAN / Q13085 Acetyl-CoA carboxylase 1; ACC1; Acetyl-Coenzyme A carboxylase alpha; ACC-alpha; EC 6.4.1.2 from Homo sapiens (Human) (see 8 papers)
Q13085 acetyl-CoA carboxylase (EC 6.4.1.2) from Homo sapiens (see 13 papers)
    29% identity, 93% coverage of query (229 bits)

ACACA_MOUSE / Q5SWU9 Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; Acetyl-CoA carboxylase 265; EC 6.4.1.2 from Mus musculus (Mouse) (see 4 papers)
Q5SWU9 acetyl-CoA carboxylase (EC 6.4.1.2) from Mus musculus (see 2 papers)
    29% identity, 93% coverage of query (229 bits)

ACACA_RAT / P11497 Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; EC 6.4.1.2 from Rattus norvegicus (Rat) (see 4 papers)
    29% identity, 93% coverage of query (224 bits)

ACC1 / Q38970 acetyl-CoA carboxylase 1 (EC 6.4.1.2) from Arabidopsis thaliana (see 2 papers)
ACC1_ARATH / Q38970 Acetyl-CoA carboxylase 1; AtACC1; Protein EMBRYO DEFECTIVE 22; Protein GURKE; Protein PASTICCINO 3; EC 6.4.1.2; EC 6.3.4.14 from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
Q38970 acetyl-CoA carboxylase (EC 6.4.1.2) from Arabidopsis thaliana (see paper)
    27% identity, 94% coverage of query (214 bits)

ACAC_SCHPO / P78820 Acetyl-CoA carboxylase; ACC; Cell untimely torn protein 6; EC 6.4.1.2; EC 6.3.4.14 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
cut6 / RF|NP_593271.1 acetyl-CoA/biotin carboxylase; EC 6.3.4.14 from Schizosaccharomyces pombe (see 2 papers)
    27% identity, 93% coverage of query (196 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory