Searching for up to 100 curated homologs for WP_066921524.1 NCBI__GCF_001579945.1:WP_066921524.1 (447 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
2vr1A Crystal structure of biotin carboxylase from e. Coli in complex with atp analog, adpcf2p.
71% identity, 100% coverage of query (662 bits)
4mv4A Crystal structure of biotin carboxylase from haemophilus influenzae in complex with amppcp and mg2
70% identity, 100% coverage of query (650 bits)
6oi8A Crystal structure of haemophilus influenzae biotin carboxylase complexed with 7-((1r,5s,6s)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl)- 6-(2-chloro-6-(pyridin-3-yl)phenyl)pyrido[2,3-d]pyrimidin-2-amine
69% identity, 100% coverage of query (645 bits)
AccC / b3256 biotin carboxylase (EC 6.3.4.14) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
accC / P24182 biotin carboxylase (EC 6.3.4.14) from Escherichia coli (strain K12) (see 2 papers)
ACCC_ECOLI / P24182 Biotin carboxylase; Acetyl-coenzyme A carboxylase biotin carboxylase subunit A; EC 6.3.4.14 from Escherichia coli (strain K12) (see 3 papers)
P24182 biotin carboxylase (EC 6.3.4.14) from Escherichia coli (see 7 papers)
fabE / AAA23409.1 biotin carboxylase from Escherichia coli (see 4 papers)
71% identity, 100% coverage of query (644 bits)
A4SVB6 biotin carboxylase (EC 6.3.4.14) from Polynucleobacter asymbioticus QLW-P1DMWA-1 (see paper)
72% identity, 99% coverage of query (644 bits)
6oi9A Crystal structure of e. Coli biotin carboxylase complexed with 7-[3- (aminomethyl)pyrrolidin-1-yl]-6-(2,6-dichlorophenyl)pyrido[2,3- d]pyrimidin-2-amine
71% identity, 100% coverage of query (644 bits)
2w71A Crystal structure of biotin carboxylase from e. Coli in complex with the imidazole-pyrimidine inhibitor
71% identity, 100% coverage of query (644 bits)
2w70A Crystal structure of biotin carboxylase from e. Coli in complex with the amino-thiazole-pyrimidine fragment
71% identity, 100% coverage of query (644 bits)
2w6zA Crystal structure of biotin carboxylase from e. Coli in complex with the 3-(3-methyl-but-2-enyl)-3h-purin-6-ylamine fragment
71% identity, 100% coverage of query (644 bits)
2w6qA Crystal structure of biotin carboxylase from e. Coli in complex with the triazine-2,4-diamine fragment
71% identity, 100% coverage of query (644 bits)
2w6pA Crystal structure of biotin carboxylase from e. Coli in complex with 5-methyl-6-phenyl-quinazoline-2,4-diamine
71% identity, 100% coverage of query (644 bits)
2w6mA Crystal structure of biotin carboxylase from e. Coli in complex with amino-oxazole fragment series
71% identity, 100% coverage of query (644 bits)
2v5aA Crystal structure of biotin carboxylase from e.Coli in complex with potent inhibitor 3
71% identity, 100% coverage of query (644 bits)
2v58A Crystal structure of biotin carboxylase from e.Coli in complex with potent inhibitor 1
71% identity, 100% coverage of query (644 bits)
1dv2A / P24182 The structure of biotin carboxylase, mutant e288k, complexed with atp (see paper)
71% identity, 100% coverage of query (643 bits)
2vqdA / P37798 Crystal structure of biotin carboxylase from pseudomonas aeruginosa complexed with ampcp (see paper)
70% identity, 100% coverage of query (643 bits)
3jziA Crystal structure of biotin carboxylase from e. Coli in complex with benzimidazole series
71% identity, 100% coverage of query (643 bits)
2w6oA Crystal structure of biotin carboxylase from e. Coli in complex with 4-amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment
71% identity, 100% coverage of query (643 bits)
2w6nA Crystal structure of biotin carboxylase from e. Coli in complex with amino-oxazole fragment series
71% identity, 100% coverage of query (643 bits)
2v59A Crystal structure of biotin carboxylase from e.Coli in complex with potent inhibitor 2
71% identity, 100% coverage of query (643 bits)
4mv3A Crystal structure of biotin carboxylase from haemophilus influenzae in complex with amppcp and bicarbonate
69% identity, 100% coverage of query (643 bits)
3jzfB Crystal structure of biotin carboxylase from e. Coli in complex with benzimidazoles series
71% identity, 100% coverage of query (642 bits)
3rupA Crystal structure of e.Coli biotin carboxylase in complex with two adp and two ca ions
71% identity, 99% coverage of query (641 bits)
3g8cA Crystal structure of biotin carboxylase in complex with biotin, bicarbonate, adp and mg ion
71% identity, 99% coverage of query (641 bits)
P43873 biotin carboxylase (EC 6.3.4.14) from Haemophilus influenzae (see paper)
70% identity, 100% coverage of query (636 bits)
Q12EJ0 biotin carboxylase (EC 6.3.4.14) from Polaromonas sp. (see paper)
70% identity, 100% coverage of query (636 bits)
P43873 Biotin carboxylase; Acetyl-coenzyme A carboxylase biotin carboxylase subunit A; EC 6.3.4.14 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
70% identity, 100% coverage of query (636 bits)
1dv1A Structure of biotin carboxylase (apo)
69% identity, 100% coverage of query (635 bits)
2j9gA Crystal structure of biotin carboxylase from e. Coli in complex with amppnp and adp
71% identity, 100% coverage of query (635 bits)
6ojhA / P43873 Crystal structure of haemophilus influenzae biotin carboxylase complexed with (r)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl) pyrido[2,3-d]pyrimidin-2-amine
70% identity, 100% coverage of query (634 bits)
2j9gB Crystal structure of biotin carboxylase from e. Coli in complex with amppnp and adp
70% identity, 100% coverage of query (630 bits)
1dv1B / P24182 Structure of biotin carboxylase (apo) (see paper)
68% identity, 100% coverage of query (627 bits)
4mv1A Crystal structure of biotin carboxylase from haemophilus influenzae in complex with adp and phosphate
68% identity, 99% coverage of query (624 bits)
C1DLJ7 biotin carboxylase (EC 6.3.4.14) from Azotobacter vinelandii (see paper)
70% identity, 100% coverage of query (622 bits)
4rzqA / P43873 Structural analysis of substrate, reaction intermediate and product binding in haemophilus influenzae biotin carboxylase (see paper)
67% identity, 100% coverage of query (611 bits)
4mv7A Crystal structure of biotin carboxylase form haemophilus influenzae in complex with phosphonoformate
66% identity, 99% coverage of query (599 bits)
4mv6A Crystal structure of biotin carboxylase from haemophilus influenzae in complex with phosphonoacetamide
66% identity, 99% coverage of query (598 bits)
4mv9A Crystal structure of biotin carboxylase from haemophilus influenzae in complex with bicarbonate
65% identity, 100% coverage of query (590 bits)
Q3A2P1 biotin carboxylase (EC 6.3.4.14) from Syntrophotalea carbinolica (see paper)
61% identity, 99% coverage of query (545 bits)
pycA / O27939 pyruvate carboxylase subunit A (EC 6.4.1.1) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see paper)
55% identity, 100% coverage of query (511 bits)
Q54755 biotin carboxylase (EC 6.3.4.14) from Synechococcus sp. (see paper)
56% identity, 99% coverage of query (509 bits)
PYCA_METJA / Q58626 Pyruvate carboxylase subunit A; Pyruvic carboxylase A; EC 6.4.1.1 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
56% identity, 99% coverage of query (509 bits)
Q10YA8 biotin carboxylase (EC 6.3.4.14) from Trichodesmium erythraeum (see paper)
57% identity, 98% coverage of query (504 bits)
pycA / Q6M0D0 pyruvate carboxylase subunit A (EC 6.4.1.1) from Methanococcus maripaludis (strain S2 / LL) (see paper)
54% identity, 99% coverage of query (499 bits)
CAC2 / O04983 biotin carboxylase (EC 6.3.4.14) from Arabidopsis thaliana (see paper)
ACCC_ARATH / O04983 Biotin carboxylase, chloroplastic; Acetyl-coenzyme A carboxylase biotin carboxylase subunit A; EC 6.3.4.14 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
53% identity, 98% coverage of query (478 bits)
F2WMV4 biotin carboxylase (EC 6.3.4.14) from Jatropha curcas (see paper)
53% identity, 98% coverage of query (472 bits)
2vpqB / A0A0H3JRR2 Crystal structure of biotin carboxylase from s. Aureus complexed with amppnp (see paper)
53% identity, 98% coverage of query (469 bits)
A4APF1 biotin carboxylase (EC 6.3.4.14) from Maribacter sp. HTCC2170 (see paper)
53% identity, 99% coverage of query (464 bits)
8hz4A / A9W9X0 The tetrameric structure of biotin carboxylase from chloroflexus aurantiacus in complex with bicarbonate (see paper)
54% identity, 99% coverage of query (461 bits)
accC / A9W9X0 biotin carboxylase (EC 6.3.4.14) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
A9W9X0 biotin carboxylase (EC 6.3.4.14) from Chloroflexus aurantiacus (see paper)
55% identity, 99% coverage of query (449 bits)
PCCA_HALMT / I3R7G3 Propionyl-CoA carboxylase, biotin carboxylase and biotin-carboxyl carrier subunit; PCC; EC 6.4.1.3; EC 6.3.4.14 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
I3R7G3 propionyl-CoA carboxylase (subunit 3/3) (EC 6.4.1.3) from Haloferax mediterranei (see paper)
52% identity, 99% coverage of query (449 bits)
MCCA_ORYSJ / Q2QMG2 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
50% identity, 99% coverage of query (445 bits)
Dsui_0516 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dechlorosoma suillum PS
49% identity, 99% coverage of query (433 bits)
Q9FAF5 biotin carboxylase (EC 6.3.4.14) from Myxococcus xanthus (see paper)
52% identity, 99% coverage of query (431 bits)
MCCA_ARATH / Q42523 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q42523 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Arabidopsis thaliana (see 2 papers)
49% identity, 98% coverage of query (431 bits)
ACCA1_MYCTU / P9WPQ3 Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit; EC 6.3.4.14 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
CAA79609.1 biotin carboxyl carrier protein from Mycobacterium tuberculosis (see paper)
49% identity, 99% coverage of query (430 bits)
2OCS_HYDTT / D3DJ42 2-oxoglutarate carboxylase small subunit; 2-oxoglutarate carboxylase beta subunit; EC 6.4.1.7 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see 2 papers)
51% identity, 99% coverage of query (428 bits)
7kctA / D3DJ42 Crystal structure of the hydrogenobacter thermophilus 2-oxoglutarate carboxylase (ogc) biotin carboxylase (bc) domain dimer in complex with adenosine 5'-diphosphate magnesium salt (mgadp), adenosine 5'- diphosphate (adp, and bicarbonate anion (hydrogen carbonate/hco3-) (see paper)
51% identity, 99% coverage of query (427 bits)
atuF / Q9HZV6 cis-geranyl-CoA carboxylase α-subunit (EC 6.4.1.5) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
50% identity, 99% coverage of query (426 bits)
A0A1U7EYC1 biotin carboxylase (EC 6.3.4.14) from Natronomonas pharaonis (see paper)
50% identity, 100% coverage of query (426 bits)
3ouuA / Q0P8W7 Crystal structure of biotin carboxylase-beta-gamma-atp complex from campylobacter jejuni
50% identity, 99% coverage of query (422 bits)
3ouzA Crystal structure of biotin carboxylase-adp complex from campylobacter jejuni
50% identity, 99% coverage of query (422 bits)
8sgxX / A0A640KC69 Leishmania tarentolae propionyl-coa carboxylase (alpha-4-beta-6) (see paper)
48% identity, 98% coverage of query (419 bits)
MCCC1 / Q96RQ3 3-methylcrotonyl-CoA carboxylase α subunit (EC 6.4.1.4) from Homo sapiens (see 4 papers)
MCCA_HUMAN / Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Homo sapiens (Human) (see 15 papers)
48% identity, 98% coverage of query (419 bits)
AO356_01595 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2C3
50% identity, 99% coverage of query (416 bits)
Pf1N1B4_3984 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N1B4
50% identity, 99% coverage of query (416 bits)
Q9HPP8 biotin carboxylase (EC 6.3.4.14) from Halobacterium salinarum (see paper)
48% identity, 99% coverage of query (414 bits)
Pf6N2E2_2194 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2E2
50% identity, 99% coverage of query (412 bits)
xccC / Q5P8S2 4-hydroxyacetophenone carboxylase biotin carboxylase subunit from Aromatoleum aromaticum (strain EbN1) (see paper)
47% identity, 98% coverage of query (411 bits)
Msed_0147 / A4YD22 acyl CoA carboxylase biotin carboxyl carrier protein subunit from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see paper)
Q8J2Z4 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (EC 6.4.1.2) from Metallosphaera sedula (see 2 papers)
46% identity, 99% coverage of query (410 bits)
PCCA_PIG / P0DTA4 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Sus scrofa (Pig) (see paper)
47% identity, 98% coverage of query (407 bits)
MCCA_MOUSE / Q99MR8 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Mus musculus (Mouse) (see paper)
47% identity, 98% coverage of query (405 bits)
accC / Q877I5 acyl CoA carboxylase biotin carboxylase subunit (EC 2.1.3.15; EC 6.4.1.3; EC 6.3.4.14) from Acidianus brierleyi (see 2 papers)
Q877I5 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (subunit 2/3) (EC 6.4.1.2); propionyl-CoA carboxylase (subunit 1/3) (EC 6.4.1.3) from Acidianus brierleyi (see 2 papers)
accC / BAC55867.1 biotin carboxylase subunit of acetyl-CoA carboxylase from Acidianus brierleyi (see paper)
46% identity, 99% coverage of query (404 bits)
7ybuA / P05165 Human propionyl-coenzyme a carboxylase
47% identity, 98% coverage of query (403 bits)
PCCA / P05165 propionyl-CoA carboxylase α chain, mitochondrial (EC 6.4.1.3) from Homo sapiens (see 4 papers)
PCCA_HUMAN / P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Homo sapiens (Human) (see 11 papers)
P05165 propionyl-CoA carboxylase (subunit 1/2) (EC 6.4.1.3) from Homo sapiens (see paper)
47% identity, 98% coverage of query (403 bits)
PCCA_MOUSE / Q91ZA3 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Mus musculus (Mouse) (see paper)
47% identity, 98% coverage of query (403 bits)
liuD / Q9I299 methylcrotonyl-CoA carboxylase α-subunit (EC 6.4.1.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I299 methylcrotonoyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.4) from Pseudomonas aeruginosa (see 3 papers)
50% identity, 99% coverage of query (403 bits)
PYC_BACSU / Q9KWU4 Pyruvate carboxylase; Pyruvic carboxylase; PYC; EC 6.4.1.1 from Bacillus subtilis (strain 168) (see 2 papers)
47% identity, 98% coverage of query (402 bits)
SM_b21124 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Sinorhizobium meliloti 1021
50% identity, 99% coverage of query (401 bits)
Dshi_0723 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dinoroseobacter shibae DFL-12
46% identity, 99% coverage of query (401 bits)
jadJ / Q9XCV7 acetyl CoA carboxylase monomer (EC 6.4.1.2) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
47% identity, 98% coverage of query (400 bits)
pccA / Q3J4D9 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see paper)
47% identity, 98% coverage of query (400 bits)
Sama_1359 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Shewanella amazonensis SB2B
49% identity, 99% coverage of query (399 bits)
Q29RK2 pyruvate carboxylase (EC 6.4.1.1) from Bos taurus (see paper)
48% identity, 98% coverage of query (399 bits)
PYC_MOUSE / Q05920 Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase; PCB; EC 6.4.1.1 from Mus musculus (Mouse) (see paper)
48% identity, 98% coverage of query (399 bits)
PC / P11498 pyruvate carboxylase, mitochondrial (EC 6.4.1.1) from Homo sapiens (see 5 papers)
PYC_HUMAN / P11498 Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase; PCB; EC 6.4.1.1 from Homo sapiens (Human) (see 5 papers)
P11498 pyruvate carboxylase (EC 6.4.1.1) from Homo sapiens (see 5 papers)
48% identity, 98% coverage of query (395 bits)
7wtdC Cryo-em structure of human pyruvate carboxylase with acetyl-coa in the intermediate state 1
48% identity, 98% coverage of query (395 bits)
7wtbB / P11498 Cryo-em structure of human pyruvate carboxylase with acetyl-coa (see paper)
48% identity, 98% coverage of query (395 bits)
5vyzA Crystal structure of lactococcus lactis pyruvate carboxylase in complex with cyclic-di-amp (see paper)
46% identity, 98% coverage of query (390 bits)
7zz3A Cryo-em structure of "bc react" conformation of lactococcus lactis pyruvate carboxylase with acetyl-coa
46% identity, 98% coverage of query (390 bits)
7zyyA Cryo-em structure of lactococcus lactis pyruvate carboxylase with acetyl-coa
46% identity, 98% coverage of query (389 bits)
8rthA / Q57YQ4 Trypanosoma brucei 3-methylcrotonyl-coa carboxylase (see paper)
46% identity, 98% coverage of query (387 bits)
PYC_STAAM / A0A0H3JRU9 Pyruvate carboxylase; EC 6.4.1.1 from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see 3 papers)
A0A0H3JRU9 pyruvate carboxylase (EC 6.4.1.1) from Staphylococcus aureus (see 4 papers)
45% identity, 98% coverage of query (384 bits)
PCCA_RUEPO / Q5LUF3 Propionyl-CoA carboxylase alpha chain; EC 6.4.1.3 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
Q5LUF3 propionyl-CoA carboxylase (EC 6.4.1.3) from Ruegeria pomeroyi (see paper)
44% identity, 98% coverage of query (383 bits)
8j78I / Q96RQ3 Human 3-methylcrotonyl-coa carboxylase in bccp-h2 state
46% identity, 98% coverage of query (380 bits)
3tw6B / Q2K340 Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a (see paper)
45% identity, 98% coverage of query (375 bits)
3n6rG / Q5LUF3 Crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) (see paper)
43% identity, 98% coverage of query (373 bits)
3bg5A / A0A0H3JRU9 Crystal structure of staphylococcus aureus pyruvate carboxylase (see paper)
43% identity, 98% coverage of query (363 bits)
3hb9A Crystal structure of s. Aureus pyruvate carboxylase a610t mutant
43% identity, 98% coverage of query (350 bits)
8hz5A / A9WKH8 The homodimer of a biotin carboxylase isoform from chloroflexus aurantiacus (see paper)
46% identity, 96% coverage of query (348 bits)
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Lawrence Berkeley National Laboratory