Sites on a Tree

 

Searching for up to 100 curated homologs for WP_068173818.1 NCBI__GCF_001592305.1:WP_068173818.1 (345 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YjfF / b4231 galactofuranose ABC transporter putative membrane subunit YjtF (EC 7.5.2.9) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
YjfF / P37772 galactofuranose ABC transporter putative membrane subunit YjtF (EC 7.5.2.9) from Escherichia coli (strain K12) (see 3 papers)
YJFF_ECOLI / P37772 Inner membrane ABC transporter permease protein YjfF from Escherichia coli (strain K12) (see paper)
    52% identity, 92% coverage of query (295 bits)

Shewana3_2076 L-arabinose ABC transporter, permease component 2 AraZ from Shewanella sp. ANA-3
    52% identity, 86% coverage of query (271 bits)

FRUG_BIFLO / Q8G845 Fructose import permease protein FruG from Bifidobacterium longum (strain NCC 2705) (see paper)
    41% identity, 90% coverage of query (195 bits)

TC 3.A.1.2.13 / A6VKS9 RbsC, component of The probable autoinducer-2 (AI-2;, a furanosyl borate diester: 3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Shao et al., 2007) (50-70% identical to RbsABC of E. coli; TC# 3.A.1.2.1) from Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
    37% identity, 85% coverage of query (147 bits)

PS417_11895 Inositol transport system permease protein from Pseudomonas simiae WCS417
    32% identity, 97% coverage of query (144 bits)

TC 3.A.1.2.19 / Q9X050 ABC-type transporter, integral membrane subunit, component of D-ribose porter (Nanavati et al., 2006). Induced by ribose from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    33% identity, 93% coverage of query (143 bits)

PS417_12060 xylitol ABC transporter, permease component from Pseudomonas simiae WCS417
    36% identity, 97% coverage of query (139 bits)

eryF / Q2YIY3 putative erythritol ABC transporter membrane protein from Brucella abortus (strain 2308) (see 3 papers)
    33% identity, 99% coverage of query (136 bits)

HSERO_RS03645 D-mannose ABC transporter, permease component from Herbaspirillum seropedicae SmR1
    35% identity, 85% coverage of query (135 bits)

AO353_21390 m-Inositol ABC transporter, permease component (iatP) from Pseudomonas fluorescens FW300-N2E3
    32% identity, 84% coverage of query (134 bits)

TC 3.A.1.2.20 / G4FGN4 Putative beta-xyloside ABC transporter, permease component, component of Glucose porter. Also bind xylose (Boucher and Noll 2011). Induced by glucose (Frock et al. 2012). Directly regulated by glucose-responsive regulator GluR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    34% identity, 85% coverage of query (134 bits)

RbsC / b3750 ribose ABC transporter membrane subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsC / P0AGI1 ribose ABC transporter membrane subunit from Escherichia coli (strain K12) (see 4 papers)
RBSC_ECOLI / P0AGI1 Ribose import permease protein RbsC from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.2.1 / P0AGI1 Ribose transport system permease protein RbsC aka B3750, component of Ribose porter from Escherichia coli (see 6 papers)
    37% identity, 92% coverage of query (134 bits)

TC 3.A.1.2.16 / Q1M4Q8 Erythritol permease, component of ABC transporter, component of The erythritol uptake permease, EryEFG (Yost et al., 2006) (probably orthologous to 3.A.1.2.11) from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    32% identity, 96% coverage of query (130 bits)

YphD / b2546 putative ABC transporter membrane subunit YphD from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    36% identity, 84% coverage of query (129 bits)

AraH / b4460 arabinose ABC transporter membrane subunit (EC 7.5.2.13; EC 7.5.2.12) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
araH / P0AE26 arabinose ABC transporter membrane subunit (EC 7.5.2.13) from Escherichia coli (strain K12) (see paper)
ARAH_ECOLI / P0AE26 L-arabinose transport system permease protein AraH from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.2 / P0AE26 L-arabinose transport system permease protein araH aka b4460, component of Arabinose porter from Escherichia coli (see 7 papers)
araH / GB|AAN43497.1 L-arabinose ABC transporter, permease protein AraH from Escherichia coli K12 (see 2 papers)
    35% identity, 79% coverage of query (127 bits)

RR42_RS03365 fructose ABC transporter, permease component (FrcC) from Cupriavidus basilensis FW507-4G11
    34% identity, 92% coverage of query (124 bits)

HSERO_RS11490 D-ribose ABC transporter, permease component RbsC from Herbaspirillum seropedicae SmR1
    32% identity, 87% coverage of query (117 bits)

PS417_18395 D-ribose ABC transporter, permease component RbsC from Pseudomonas simiae WCS417
    33% identity, 94% coverage of query (113 bits)

Build an alignment

Build an alignment for WP_068173818.1 and 18 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

PGA1_c07310 Inositol transport system permease protein from Phaeobacter inhibens BS107
    28% identity, 96% coverage of query (112 bits)

XylH / b3568 xylose ABC transporter membrane subunit (EC 7.5.2.13; EC 7.5.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
XylH / P0AGI4 xylose ABC transporter membrane subunit (EC 7.5.2.13) from Escherichia coli (strain K12) (see paper)
TC 3.A.1.2.4 / P0AGI4 Xylose transport system permease protein XylH aka B3568, component of Xylose porter from Escherichia coli (see 4 papers)
xylH / RF|NP_418025 D-xylose ABC transporter, permease protein from Escherichia coli K12 (see 7 papers)
    31% identity, 97% coverage of query (110 bits)

Pf6N2E2_5970 ABC transporter for D-galactose/L-arabinose, permease component from Pseudomonas fluorescens FW300-N2E2
    30% identity, 94% coverage of query (107 bits)

Pf1N1B4_409 ABC transporter for D-galactose/L-arabinose, permease component from Pseudomonas fluorescens FW300-N1B4
    30% identity, 95% coverage of query (107 bits)

BPHYT_RS16925 D-galactose ABC transporter, permease component from Burkholderia phytofirmans PsJN
    30% identity, 99% coverage of query (107 bits)

FRCC_RHIML / Q9F9B1 Fructose import permease protein FrcC from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
TC 3.A.1.2.7 / Q9F9B1 FrcC, component of Fructose/mannose/ribose porter from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
    33% identity, 84% coverage of query (107 bits)

Pf1N1B4_6033 D-ribose ABC transporter, permease component RbsC from Pseudomonas fluorescens FW300-N1B4
    33% identity, 88% coverage of query (107 bits)

TC 3.A.1.2.18 / Q9WXW7 ABC-type transporter, integral membrane subunit, component of Xylose porter (Nanavati et al. 2006). Regulated by xylose-responsive regulator XylR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    33% identity, 79% coverage of query (107 bits)

AlsC / b4086 D-allose ABC transporter membrane subunit (EC 7.5.2.8) from Escherichia coli K-12 substr. MG1655 (see paper)
AlsC / P32720 D-allose ABC transporter membrane subunit (EC 7.5.2.8) from Escherichia coli (strain K12) (see paper)
ALSC_ECOLI / P32720 D-allose transport system permease protein AlsC from Escherichia coli (strain K12) (see paper)
TC 3.A.1.2.6 / P32720 AlsC aka B4086, component of D-allose porter from Escherichia coli (see 6 papers)
    30% identity, 87% coverage of query (97.8 bits)

HSERO_RS05255 ABC transporter for L-fucose, permease component from Herbaspirillum seropedicae SmR1
    32% identity, 78% coverage of query (95.9 bits)

FRUF_BIFLO / Q8G846 Fructose import permease protein FruF from Bifidobacterium longum (strain NCC 2705) (see paper)
    32% identity, 82% coverage of query (95.5 bits)

BPHYT_RS34240 ABC transporter for L-rhamnose/L-fucose/xylitol, permease component from Burkholderia phytofirmans PsJN
    29% identity, 86% coverage of query (94.7 bits)

Shewana3_2075 L-arabinose ABC transporter, permease component 1 AraW from Shewanella sp. ANA-3
    29% identity, 79% coverage of query (87.8 bits)

LSRD_SALTY / Q8ZKQ2 Autoinducer 2 import system permease protein LsrD; AI-2 import system permease protein LsrD from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    30% identity, 78% coverage of query (82.8 bits)

TC 3.A.1.2.24 / O50505 Probable ABC-type transmembrane transport protein, component of XylFGH downstream of characterized transcriptional regulator, ROK7B7 (Sco6008); XylF (Sco6009); XylG (Sco6010); XylH (Sco6011)) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    28% identity, 80% coverage of query (82.4 bits)

YdeZ / b1515 Autoinducer-2 ABC transporter membrane subunit LsrD (EC 7.6.2.13) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lsrD / P0AFS1 Autoinducer-2 ABC transporter membrane subunit LsrD (EC 7.6.2.13) from Escherichia coli (strain K12) (see 2 papers)
LSRD_ECOLI / P0AFS1 Autoinducer 2 import system permease protein LsrD; AI-2 import system permease protein LsrD from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.8 / P0AFS1 LsrD(M)AKA Inner membrane ABC transporter permease protein ydeZ, component of Autoinducer-2 (AI-2, a furanosyl borate diester: (3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Taga et al., 2001, 2003) from Escherichia coli (see 6 papers)
lsrD autoinducer 2 ABC transporter, permease protein LsrD from Escherichia coli K12 (see paper)
    30% identity, 79% coverage of query (80.1 bits)

H281DRAFT_01112 deoxynucleoside transporter, permease component 2 from Paraburkholderia bryophila 376MFSha3.1
    28% identity, 94% coverage of query (77.8 bits)

YdeY / b1514 Autoinducer-2 ABC transporter membrane subunit LsrC (EC 7.6.2.13) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lsrC / P77672 Autoinducer-2 ABC transporter membrane subunit LsrC (EC 7.6.2.13) from Escherichia coli (strain K12) (see 2 papers)
LSRC_ECOLI / P77672 Autoinducer 2 import system permease protein LsrC; AI-2 import system permease protein LsrC from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.8 / P77672 LsrC(M), component of Autoinducer-2 (AI-2, a furanosyl borate diester: (3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Taga et al., 2001, 2003) from Escherichia coli (see 6 papers)
lsrC / RF|NP_416031.1 autoinducer 2 ABC transporter, permease protein LsrC from Escherichia coli (see paper)
    31% identity, 84% coverage of query (77.4 bits)

LSRC_SALTY / Q8ZKQ3 Autoinducer 2 import system permease protein LsrC; AI-2 import system permease protein LsrC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    29% identity, 92% coverage of query (75.5 bits)

H281DRAFT_01115 deoxynucleoside transporter, permease component 1 from Paraburkholderia bryophila 376MFSha3.1
    29% identity, 70% coverage of query (58.2 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory