Searching for up to 100 curated homologs for WP_073038275.1 NCBI__GCF_900129305.1:WP_073038275.1 (352 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YeaU / b1800 D-malate/3-isopropylmalate dehydrogenase (decarboxylating) (EC 1.1.1.83; EC 1.1.1.85; EC 1.1.1.93) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
dmlA / P76251 D-malate/3-isopropylmalate dehydrogenase (decarboxylating) (EC 1.1.1.83; EC 1.1.1.85; EC 1.1.1.93) from Escherichia coli (strain K12) (see 5 papers)
DMLA_ECOLI / P76251 D-malate dehydrogenase [decarboxylating]; D-malate degradation protein A; D-malate oxidase; EC 1.1.1.83 from Escherichia coli (strain K12) (see 2 papers)
P76251 D-malate dehydrogenase (decarboxylating) (EC 1.1.1.83) from Escherichia coli (see paper)
yeaU / RF|NP_416314 D-malate dehydrogenase [decarboxylating] from Escherichia coli K12 (see 3 papers)
64% identity, 99% coverage of query (447 bits)
3flkA / Q51945 Crystal structure of tartrate dehydrogenase from pseudomonas putida in complex with nadh, oxalate and metal ion (see paper)
63% identity, 97% coverage of query (441 bits)
U05986.1 / Q51945 tartrate dehydrogenase subunit (EC 1.1.1.83; EC 1.1.1.93) from Pseudomonas putida (see 7 papers)
TTUC_PSEPU / Q51945 Tartrate dehydrogenase/decarboxylase; TDH; D-malate dehydrogenase [decarboxylating]; EC 1.1.1.93; EC 4.1.1.73; EC 1.1.1.83 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
63% identity, 97% coverage of query (434 bits)
EBL86_19295 / A0A3G6WGL6 L-tartrate dehydrogenase/D-malate dehydrogenase (decarboxylating)/meso-tartrate decarboxylase monomer (EC 1.1.1.83; EC 1.1.1.93) from Cereibacter sphaeroides (see 2 papers)
66% identity, 96% coverage of query (426 bits)
MJ0720 / Q58130 3-isopropylmalate dehydrogenase subunit (EC 1.1.1.85) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
LEU3_METJA / Q58130 3-isopropylmalate/3-methylmalate dehydrogenase; 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; IPMDH; Beta-IPM dehydrogenase; D-malate dehydrogenase [decarboxylating]; EC 1.1.1.85; EC 1.1.1.n5; EC 1.1.1.83 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
42% identity, 99% coverage of query (254 bits)
2g4oA / P9WKK9 Anomalous substructure of 3-isopropylmalate dehydrogenase (see paper)
46% identity, 94% coverage of query (248 bits)
LEU3_MYCTU / P9WKK9 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
46% identity, 94% coverage of query (248 bits)
P94929 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Mycobacterium tuberculosis variant bovis (see paper)
46% identity, 94% coverage of query (247 bits)
aksF / Q58991 NAD-dependent threo-isocitrate dehydrogenase (EC 1.1.1.87) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
AKSF_METJA / Q58991 Homoisocitrate dehydrogenase; HICDH; Homo(2)-isocitrate/homo(3)-isocitrate dehydrogenase; Isohomocitrate dehydrogenase; IHDH; NAD-dependent threo-isohomocitrate dehydrogenase; EC 1.1.1.87; EC 1.1.1.- from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58991 methanogen homoaconitase (EC 4.2.1.114) from Methanocaldococcus jannaschii (see paper)
37% identity, 99% coverage of query (237 bits)
hicdh / Q5SIJ1 homoisocitrate dehydrogenase subunit (EC 1.1.1.87) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET8 / Q5SIJ1 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET2 / Q72IW9 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 4 papers)
Q5SIJ1 homoisocitrate dehydrogenase (EC 1.1.1.87) from Thermus thermophilus (see paper)
40% identity, 99% coverage of query (232 bits)
3asjA / Q5SIJ1 Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor (see paper)
40% identity, 98% coverage of query (229 bits)
4yb4A Crystal structure of homoisocitrate dehydrogenase from thermus thermophilus in complex with homoisocitrate, magnesium ion (ii) and nadh
40% identity, 98% coverage of query (229 bits)
3asjB Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor
40% identity, 98% coverage of query (229 bits)
ecm3 / Q0X0C1 (2S,3R)-2-[(2-aminophenyl)amino]-3-carboxy-3-hydroxypropanoate dehydrogenase from Streptomyces lasalocidi (see 2 papers)
43% identity, 98% coverage of query (228 bits)
P24098 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus aquaticus (see paper)
40% identity, 98% coverage of query (218 bits)
6m3sB / A0A0H2XBX7 Dimeric isocitrate dehydrogenase from xanthomonas campestris pv. Campestris 8004
37% identity, 99% coverage of query (218 bits)
hdh / BAD06515.1 homoisocitrate dehydrogenase, partial from Deinococcus radiodurans (see paper)
39% identity, 98% coverage of query (214 bits)
6xxyA / P43860 Crystal structure of haemophilus influenzae 3-isopropylmalate dehydrogenase in complex with o-isobutenyl oxalylhydroxamate. (see paper)
39% identity, 95% coverage of query (213 bits)
P43860 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Haemophilus influenzae (see paper)
39% identity, 95% coverage of query (213 bits)
LeuB / b0073 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
leuB / P30125 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Escherichia coli (strain K12) (see 12 papers)
LEU3_ECOLI / P30125 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Escherichia coli (strain K12) (see 2 papers)
P30125 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Escherichia coli (see 2 papers)
leuB / BAA04537.1 3-isopropylmalate dehydrogenase from Escherichia coli (see paper)
39% identity, 99% coverage of query (213 bits)
P61495 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see paper)
39% identity, 98% coverage of query (208 bits)
2y42D / Q5SIY4 Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with nadh and mn (see paper)
39% identity, 98% coverage of query (207 bits)
LEU3_THET8 / Q5SIY4 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 4 papers)
Q5SIY4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see 12 papers)
39% identity, 98% coverage of query (207 bits)
P61494 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see 2 papers)
39% identity, 98% coverage of query (207 bits)
2y41A Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with ipm and mn
39% identity, 98% coverage of query (207 bits)
2ztwA Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+
39% identity, 98% coverage of query (207 bits)
LEU3_SALTY / P37412 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
P37412 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
1cnzA / P37412 3-isopropylmalate dehydrogenase (ipmdh) from salmonella typhimurium (see paper)
38% identity, 99% coverage of query (203 bits)
Q8E9N3 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Shewanella oneidensis (see 4 papers)
39% identity, 95% coverage of query (202 bits)
6lkyA / Q602J2 Crystal structure of isocitrate dehydrogenase from methylococcus capsulatus
37% identity, 96% coverage of query (201 bits)
LEU3_HEYCO / P12010 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Heyndrickxia coagulans (Weizmannia coagulans) (see paper)
35% identity, 99% coverage of query (199 bits)
3vkzA / Q8E9N3 3-isopropylmalate dehydrogenase from shewanella oneidensis mr-1 at atmospheric pressure (see paper)
38% identity, 94% coverage of query (199 bits)
LYS12_YEAST / P40495 Homoisocitrate dehydrogenase, mitochondrial; HIcDH; EC 1.1.1.87 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P40495 homoisocitrate dehydrogenase (EC 1.1.1.87) from Saccharomyces cerevisiae (see 2 papers)
37% identity, 98% coverage of query (199 bits)
D2YZL2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Shewanella benthica (see 3 papers)
37% identity, 95% coverage of query (193 bits)
lysB putative homoisocitrate dehydrogenase from Emericella nidulans (see paper)
36% identity, 99% coverage of query (192 bits)
Q4JB37 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Sulfolobus acidocaldarius (see paper)
36% identity, 99% coverage of query (191 bits)
LEU33_ARATH / Q9SA14 3-isopropylmalate dehydrogenase 3, chloroplastic; 3-IPM-DH 3; AtIMDH2; AtIMDH3; IMDH 3; Beta-IPM dehydrogenase 3; Isopropylmalate dehydrogenase 3; AtIMD3; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9SA14 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 3 papers)
37% identity, 94% coverage of query (191 bits)
2d1cA / P33197 Crystal structure of tt0538 protein from thermus thermophilus hb8
37% identity, 98% coverage of query (191 bits)
P33197 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermus thermophilus (see 2 papers)
icd / RF|YP_144801.1 isocitrate dehydrogenase (NADP(+)); EC 1.1.1.42 from Thermus thermophilus HB8 (see 2 papers)
37% identity, 98% coverage of query (191 bits)
3vmkA / D2YZL2 3-isopropylmalate dehydrogenase from shewanella benthica db21 mt-2 (see paper)
37% identity, 94% coverage of query (190 bits)
IMDH3 / Q9FMT1 isopropylmalate dehydrogenase 3 (EC 1.1.1.85) from Arabidopsis thaliana (see paper)
LEU31_ARATH / Q9FMT1 3-isopropylmalate dehydrogenase 1, chloroplastic; 3-IPM-DH 1; AtIMDH1; IMDH 1; Beta-IPM dehydrogenase 1; Isopropylmalate dehydrogenase 1; AtIMD1; Methylthioalkylmalate dehydrogenase 1; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9FMT1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 4 papers)
36% identity, 94% coverage of query (190 bits)
P29102 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Brassica napus (see paper)
37% identity, 94% coverage of query (190 bits)
4y1pB / Q4JB37 Crystal structure of 3-isopropylmalate dehydrogenase (saci_0600) from sulfolobus acidocaldarius complex with 3-isopropylmalate and mg2+ (see paper)
36% identity, 99% coverage of query (189 bits)
5j32A / P93832 Isopropylmalate dehydrogenase in complex with isopropylmalate (see paper)
37% identity, 94% coverage of query (189 bits)
LEU32_ARATH / P93832 3-isopropylmalate dehydrogenase 2, chloroplastic; 3-IPM-DH 2; AtIMDH2; AtIMDH3; IMDH 2; Beta-IPM dehydrogenase 2; Isopropylmalate dehydrogenase 2; AtIMD2; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
P93832 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 4 papers)
37% identity, 94% coverage of query (189 bits)
HICDH_PYRHO / O59394 Isocitrate/homoisocitrate dehydrogenase; HICDH; Beta-decarboxylating dehydrogenase; EC 1.1.1.286 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
37% identity, 99% coverage of query (189 bits)
5j33A Isopropylmalate dehydrogenase in complex with NAD+
37% identity, 94% coverage of query (189 bits)
G1APK3 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
36% identity, 99% coverage of query (185 bits)
LYS12_SCHPO / O14104 Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.87 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
36% identity, 99% coverage of query (185 bits)
3ty3A / O14104 Crystal structure of homoisocitrate dehydrogenase from schizosaccharomyces pombe bound to glycyl-glycyl-glycine (see paper)
36% identity, 99% coverage of query (184 bits)
IDH3A_MOUSE / Q9D6R2 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Mus musculus (Mouse) (see paper)
Q9D6R2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Mus musculus (see paper)
34% identity, 99% coverage of query (181 bits)
LEU3_SULTO / P50455 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; Beta-IPM dehydrogenase; EC 1.1.1.85 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
P50455 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Sulfurisphaera tokodaii (see 3 papers)
32% identity, 99% coverage of query (181 bits)
IDH3A_PIG / P56471 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Sus scrofa (Pig) (see paper)
34% identity, 99% coverage of query (180 bits)
LEU3_HALVD / D4GYE8 3-isopropylmalate dehydrogenase; EC 1.1.1.85 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
37% identity, 99% coverage of query (179 bits)
leuB / P24015 β-isopropylmalate dehydrogenase subunit (EC 1.1.1.85) from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) (see 2 papers)
P24015 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Leptospira interrogans (see paper)
leuB / AAA72088.1 3-isopropylmalate dehydrogenase from Leptospira borgpetersenii (see paper)
36% identity, 99% coverage of query (179 bits)
IDH3A_BOVIN / P41563 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitrate dehydrogenase subunits 3/4; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Bos taurus (Bovine) (see paper)
34% identity, 99% coverage of query (179 bits)
IDH3A_CAEEL / Q93714 Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Caenorhabditis elegans (see paper)
36% identity, 99% coverage of query (178 bits)
8grdA Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human idh3 in complex with adp and mg
33% identity, 99% coverage of query (177 bits)
5yvtA Crystal structure of the alpha gamma heterodimer of human idh3 in complex with mg(2+) and nadh
34% identity, 99% coverage of query (177 bits)
6kdyA Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD.
34% identity, 99% coverage of query (177 bits)
6kdeA / P50213 Crystal structure of the alpha beta heterodimer of human idh3 in complex with ca(2+) (see paper)
34% identity, 99% coverage of query (176 bits)
IDH3A_RAT / Q99NA5 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Rattus norvegicus (Rat) (see paper)
Q99NA5 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rattus norvegicus (see paper)
33% identity, 99% coverage of query (176 bits)
IDH3A / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3A_HUMAN / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Homo sapiens (Human) (see 5 papers)
P50213 isocitrate dehydrogenase (NAD+) (subunit 2/2) (EC 1.1.1.41) from Homo sapiens (see paper)
34% identity, 99% coverage of query (176 bits)
IDH2_SCHPO / Q9USP8 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 3 papers)
34% identity, 99% coverage of query (176 bits)
idh2 / RF|NP_595203.1 isocitrate dehydrogenase (NAD+) subunit 2; EC 1.1.1.41 from Schizosaccharomyces pombe (see 2 papers)
34% identity, 99% coverage of query (176 bits)
Q5JFV8 isocitrate-homoisocitrate dehydrogenase (EC 1.1.1.286) from Thermococcus kodakarensis (see paper)
38% identity, 99% coverage of query (176 bits)
5hn4A / Q5JFV8 Crystal structure of beta-decarboxylating dehydrogenase (tk0280) from thermococcus kodakarensis complexed with mn and homoisocitrate (see paper)
38% identity, 99% coverage of query (175 bits)
5hn6A Crystal structure of beta-decarboxylating dehydrogenase (tk0280) from thermococcus kodakarensis complexed with mn and 3-isopropylmalate
38% identity, 99% coverage of query (175 bits)
5greA Crystal structure of the alpha gamma heterodimer of human idh3 in complex with mg(2+), citrate and adp
33% identity, 99% coverage of query (174 bits)
6l59A Crystal structure of the alpha gamma heterodimer of human idh3 in complex with cit, mg and atp binding at allosteric site and mg, atp binding at active site.
33% identity, 99% coverage of query (174 bits)
P31958 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Clostridium pasteurianum (see paper)
leuB / AAC41394.1 isopropylmalate dehydrogenase from Clostridium pasteurianum (see paper)
35% identity, 99% coverage of query (173 bits)
P54354 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Bacteroides fragilis (see paper)
leuB / BAA08117.1 beta-isopropylmalate dehydrogenase from Bacteroides fragilis (see paper)
33% identity, 95% coverage of query (173 bits)
IDH-V / Q945K7 NAD+-dependent isocitrate dehydrogenase catalytic subunit (EC 1.1.1.286) from Arabidopsis thaliana (see 3 papers)
IDH5_ARATH / Q945K7 Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial; IDH-V; Isocitric dehydrogenase 5; NAD(+)-specific ICDH 5; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q945K7 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
34% identity, 97% coverage of query (172 bits)
4iwhA / Q2T7H6 Crystal structure of a 3-isopropylmalate dehydrogenase from burkholderia pseudomallei
35% identity, 94% coverage of query (171 bits)
4xxvA Crystal structure of 3-isopropylmalate dehydrogenase from burkholderia thailandensis in complex with NAD
35% identity, 94% coverage of query (171 bits)
AMT6_ALTAL / C9K7B7 3-isopropylmalate dehydrogenase AMT6; AM-toxin biosynthesis protein 6; EC 1.1.1.85 from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
36% identity, 99% coverage of query (168 bits)
1a05A / Q56268 Crystal structure of the complex of 3-isopropylmalate dehydrogenase from thiobacillus ferrooxidans with 3-isopropylmalate (see paper)
35% identity, 94% coverage of query (167 bits)
LEU3_ACIFR / Q56268 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans) (see 2 papers)
Q56268 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Acidithiobacillus ferrooxidans (see paper)
35% identity, 94% coverage of query (167 bits)
S2J6B8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Mucor circinelloides (see paper)
37% identity, 97% coverage of query (167 bits)
IDH6_ARATH / Q8LG77 Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial; IDH-VI; Isocitric dehydrogenase 6; NAD(+)-specific ICDH 6; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LG77 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
33% identity, 97% coverage of query (166 bits)
3blwF / P28241 Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits (see paper)
34% identity, 99% coverage of query (158 bits)
3blvC / P28834 Yeast isocitrate dehydrogenase with citrate bound in the regulatory subunits (see paper)
31% identity, 99% coverage of query (149 bits)
3blwA Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits
31% identity, 99% coverage of query (148 bits)
2iv0A / O29610 Thermal stability of isocitrate dehydrogenase from archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers (see paper)
32% identity, 99% coverage of query (146 bits)
P18869 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; Beta-IPM dehydrogenase; EC 1.1.1.85 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
32% identity, 100% coverage of query (145 bits)
5grfB / P51553 Crystal structure of the alpha gamma mutant (gamma-k151a) of human idh3 in complex with mg(2+), citrate and adp (see paper)
31% identity, 99% coverage of query (133 bits)
5yvtB Crystal structure of the alpha gamma heterodimer of human idh3 in complex with mg(2+) and nadh
31% identity, 99% coverage of query (133 bits)
6l57B Crystal structure of the alpha gamma heterodimer of human idh3 in complex with cit , mg and atp binding at allosteric site.
31% identity, 99% coverage of query (133 bits)
IDH3G / P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3G_HUMAN / P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; Isocitric dehydrogenase subunit gamma; NAD(+)-specific ICDH subunit gamma from Homo sapiens (Human) (see 3 papers)
P51553 isocitrate dehydrogenase (NAD+) (subunit 1/3) (EC 1.1.1.41) from Homo sapiens (see 4 papers)
31% identity, 99% coverage of query (132 bits)
Build an alignment for WP_073038275.1 and 88 homologs with ≥ 30% identity
Or download the sequences
2e5mA / Q96YK6 Crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii strain 7 (see paper)
27% identity, 94% coverage of query (120 bits)
8grdB Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human idh3 in complex with adp and mg
27% identity, 99% coverage of query (118 bits)
2d4vA / Q8GAX0 Crystal structure of NAD dependent isocitrate dehydrogenase from acidithiobacillus thiooxidans (see paper)
28% identity, 98% coverage of query (117 bits)
6kdyF Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD.
27% identity, 99% coverage of query (115 bits)
6kdyD / O43837 Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD. (see paper)
27% identity, 99% coverage of query (115 bits)
1isoA Isocitrate dehydrogenase: structure of an engineered NADP+--> NAD+ specificity-reversal mutant
27% identity, 98% coverage of query (112 bits)
IDH_PSEAB / Q02NB5 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
27% identity, 98% coverage of query (111 bits)
6c0eA / Q5ZXB6 Crystal structure of isocitrate dehydrogenase from legionella pneumophila with bound NADPH with an alpha-ketoglutarate adduct
28% identity, 93% coverage of query (110 bits)
4ajcA 3d structure of e. Coli isocitrate dehydrogenase k100m mutant in complex with alpha-ketoglutarate, calcium(ii) and adenine nucleotide phosphate
27% identity, 98% coverage of query (107 bits)
1groA Regulatory and catalytic mechanisms in escherichia coli isocitrate dehydrogenase: multiple roles for n115
27% identity, 98% coverage of query (106 bits)
IcdE / b1136 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
icd / P08200 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli (strain K12) (see 3 papers)
IDH_ECOLI / P08200 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Escherichia coli (strain K12) (see 7 papers)
P08200 [Isocitrate dehydrogenase (NADP+)] kinase (EC 2.7.11.5) from Escherichia coli (see paper)
4aj3A / P08200 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and NADP - the pseudo-michaelis complex (see paper)
27% identity, 98% coverage of query (105 bits)
4ajaA 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and thionadp
27% identity, 98% coverage of query (105 bits)
Or start over
Lawrence Berkeley National Laboratory