Searching for up to 100 curated homologs for WP_073040739.1 NCBI__GCF_900129305.1:WP_073040739.1 (439 a.a.)
Found high-coverage hits (≥70%) to 24 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PAAK_PSEPU / O33469 Phenylacetate-coenzyme A ligase; Phenylacetyl-CoA ligase; PA-CoA ligase; EC 6.2.1.30 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
45% identity, 95% coverage of query (385 bits)
paaF / CAD76926.1 phenylacetate-CoA ligase from Pseudomonas sp. Y2 (see paper)
45% identity, 96% coverage of query (384 bits)
PaaK / b1398 phenylacetate-CoA ligase (EC 6.2.1.30) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
PAAK_ECOLI / P76085 Phenylacetate-coenzyme A ligase; Phenylacetyl-CoA ligase; PA-CoA ligase; EC 6.2.1.30 from Escherichia coli (strain K12) (see 3 papers)
46% identity, 95% coverage of query (383 bits)
B4E7B5 phenylacetate-CoA ligase (EC 6.2.1.30) from Burkholderia cenocepacia (see 2 papers)
46% identity, 97% coverage of query (379 bits)
2y27B / B4E7B5 Crystal structure of paak1 in complex with atp from burkholderia cenocepacia (see paper)
46% identity, 97% coverage of query (378 bits)
2y4nA Paak1 in complex with phenylacetyl adenylate
46% identity, 97% coverage of query (371 bits)
paaK / Q9L9C1 phenylacetate-CoA ligase (aerobic) (EC 6.2.1.30) from Aromatoleum evansii (see paper)
PAAK_AROEV / Q9L9C1 Phenylacetate-coenzyme A ligase; Phenylacetyl-CoA ligase; PA-CoA ligase; EC 6.2.1.30 from Aromatoleum evansii (Azoarcus evansii) (see 3 papers)
pacD / CAC10605.1 aerobic phenylacetate-CoA ligase from Aromatoleum evansii (see paper)
45% identity, 97% coverage of query (365 bits)
4r1mA / Q8AAN6 Crystal structure of a putative acyl-coa ligase (bt_0428) from bacteroides thetaiotaomicron vpi-5482 at 2.48 a resolution
42% identity, 99% coverage of query (362 bits)
2y4oA / B4EL89 Crystal structure of paak2 in complex with phenylacetyl adenylate (see paper)
44% identity, 93% coverage of query (360 bits)
B4EL89 phenylacetate-CoA ligase (EC 6.2.1.30) from Burkholderia cenocepacia (see 2 papers)
44% identity, 96% coverage of query (360 bits)
4r1lA Crystal structure of a putative acyl-coa ligase (bt_0428) from bacteroides thetaiotaomicron vpi-5482 at 2.42 a resolution
43% identity, 95% coverage of query (360 bits)
2y4oB Crystal structure of paak2 in complex with phenylacetyl adenylate
44% identity, 93% coverage of query (360 bits)
PAAK_THET2 / Q72K16 Phenylacetate-coenzyme A ligase; Phenylacetyl-CoA ligase; PA-CoA ligase; EC 6.2.1.30 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
Q72K16 phenylacetate-CoA ligase (EC 6.2.1.30) from Thermus thermophilus (see paper)
42% identity, 98% coverage of query (355 bits)
6he0A / I3VE75 Crystal structure of 2-hydroxyisobutyryl-coa ligase (hcl) in complex with 2-hib-amp and coa in the thioesterfication state (see paper)
30% identity, 95% coverage of query (181 bits)
Build an alignment for WP_073040739.1 and 14 homologs with ≥ 30% identity
Or download the sequences
mdpP / A2SP20 2-hydroxyisobutanoate-CoA ligase from Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) (see paper)
29% identity, 98% coverage of query (180 bits)
bal / Q5P5G7 benzoylacetate-CoA ligase from Aromatoleum aromaticum (strain EbN1) (see paper)
32% identity, 96% coverage of query (176 bits)
6hdyA Crystal structure of 2-hydroxyisobutyryl-coa ligase (hcl) in the postadenylation state in complex with s3-hb-amp
29% identity, 98% coverage of query (172 bits)
6hdxA Crystal structure of 2-hydroxyisobutyryl-coa ligase (hcl) in the postadenylation state in complex with r3-hib-amp
29% identity, 98% coverage of query (172 bits)
ftsA / Q50751 factor 390 synthetase from Methanothermobacter thermautotrophicus (see 3 papers)
31% identity, 73% coverage of query (156 bits)
ind3 / A0A0D4BST1 4,5-dehydro-L-arginine--indolmycenate ligase from Streptomyces griseus subsp. griseus (see paper)
30% identity, 73% coverage of query (111 bits)
6sixB / A0A022MRT4 Paak family amp-ligase with anp (see paper)
26% identity, 92% coverage of query (111 bits)
6siwA Paak family amp-ligase with amp
26% identity, 92% coverage of query (110 bits)
6siyA Paak family amp-ligase with amp and substrate
26% identity, 92% coverage of query (110 bits)
ptmA1 / D8L2T7 7α-hydroxy-ent-kauranol-carboxylate adenylase from Streptomyces platensis (see paper)
27% identity, 83% coverage of query (92.4 bits)
Or start over
Lawrence Berkeley National Laboratory