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Searching for up to 100 curated homologs for WP_078429924.1 NCBI__GCF_002019605.1:WP_078429924.1 (213 a.a.)

Found high-coverage hits (≥70%) to 53 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q4FQF7 ATP phosphoribosyltransferase (EC 2.4.2.17) from Psychrobacter arcticus (see 2 papers)
    49% identity, 96% coverage of query (184 bits)

6fcaA / Q4FQF7 Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with prpp
    49% identity, 96% coverage of query (183 bits)

6fcyA Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with prpp and adp
    49% identity, 96% coverage of query (183 bits)

6fd9A Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with amp
    49% identity, 96% coverage of query (183 bits)

6fcwA Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with pratp
    49% identity, 96% coverage of query (183 bits)

6fctA Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with prpp and atp
    49% identity, 96% coverage of query (183 bits)

AO356_06970 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens FW300-N2C3
    47% identity, 97% coverage of query (180 bits)

Pf6N2E2_3253 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens FW300-N2E2
    47% identity, 97% coverage of query (180 bits)

Pf1N1B4_1067 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens FW300-N1B4
    47% identity, 97% coverage of query (179 bits)

PS417_04415 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas simiae WCS417
    47% identity, 97% coverage of query (178 bits)

AO353_05115 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens FW300-N2E3
    46% identity, 97% coverage of query (178 bits)

HP15_2429 ATP phosphoribosyltransferase (EC 2.4.2.17) from Marinobacter adhaerens HP15
    46% identity, 98% coverage of query (177 bits)

BPHYT_RS17715 ATP phosphoribosyltransferase (EC 2.4.2.17) from Burkholderia phytofirmans PsJN
    46% identity, 97% coverage of query (176 bits)

PfGW456L13_5001 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens GW456-L13
    46% identity, 97% coverage of query (176 bits)

HSERO_RS20350 ATP phosphoribosyltransferase (EC 2.4.2.17) from Herbaspirillum seropedicae SmR1
    44% identity, 97% coverage of query (173 bits)

Psest_3299 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas stutzeri RCH2
    46% identity, 97% coverage of query (173 bits)

PP_0965 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas putida KT2440
    45% identity, 97% coverage of query (172 bits)

AZOBR_RS19500 ATP phosphoribosyltransferase (EC 2.4.2.17) from Azospirillum brasilense Sp245
    43% identity, 98% coverage of query (161 bits)

Q02129 ATP phosphoribosyltransferase (EC 2.4.2.17) from Lactococcus lactis (see paper)
    44% identity, 94% coverage of query (157 bits)

1z7nF / Q02129 Atp phosphoribosyl transferase (hiszg atp-prtase) from lactococcus lactis with bound prpp substrate (see paper)
    44% identity, 94% coverage of query (156 bits)

1z7mE Atp phosphoribosyl transferase (hiszg atp-prtase) from lactococcus lactis
    44% identity, 94% coverage of query (153 bits)

Ga0059261_1280 ATP phosphoribosyltransferase (EC 2.4.2.17) from Sphingomonas koreensis DSMZ 15582
    41% identity, 99% coverage of query (151 bits)

1usyG / Q9X0D2 Atp phosphoribosyl transferase (hisg:hisz) complex from thermotoga maritima (see paper)
    38% identity, 98% coverage of query (141 bits)

2vd3A / O27550 The structure of histidine inhibited hisg from methanobacterium thermoautotrophicum
    34% identity, 97% coverage of query (112 bits)

Q9Z472 ATP phosphoribosyltransferase (EC 2.4.2.17) from Corynebacterium glutamicum (see 2 papers)
    32% identity, 97% coverage of query (96.7 bits)

7dahC / Q9KSX4 Adenosine triphosphate phosphoribosyltransferase from vibrio cholerae in complex with atp and prpp
    32% identity, 92% coverage of query (92.8 bits)

5u99A Transition state analysis of adenosine triphosphate phosphoribosyltransferase
    32% identity, 97% coverage of query (92.0 bits)

HIS1 / GB|CAA58751.1 ATP phosphoribosyltransferase; EC 2.4.2.17 from Candida albicans (see paper)
    31% identity, 98% coverage of query (90.9 bits)

HIS1_MYCTU / P9WMN1 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
5lhtA / P9WMN1 Atp phosphoribosyltransferase from mycobacterium tuberculosis in complex with the allosteric activator 3-(2-thienyl)-l-alanine (see paper)
    30% identity, 97% coverage of query (89.4 bits)

1nh8A Atp phosphoribosyltransferase (atp-prtase) from mycobacterium tuberculosis in complex with amp and histidine
    32% identity, 97% coverage of query (89.4 bits)

HisG / b2019 ATP phosphoribosyltransferase (EC 2.4.2.17) from Escherichia coli K-12 substr. MG1655 (see paper)
hisG / P60757 ATP phosphoribosyltransferase (EC 2.4.2.17) from Escherichia coli (strain K12) (see 36 papers)
HIS1_ECOLI / P60757 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Escherichia coli (strain K12) (see 4 papers)
hisG / RF|NP_416523 ATP phosphoribosyltransferase from Escherichia coli K12 (see paper)
    31% identity, 96% coverage of query (84.0 bits)

1h3dA / P60757 Structure of the e.Coli atp-phosphoribosyltransferase (see paper)
    31% identity, 96% coverage of query (83.6 bits)

1q1kA Structure of atp-phosphoribosyltransferase from e. Coli complexed with pr-atp
    31% identity, 96% coverage of query (83.6 bits)

HIS1_SALTY / P00499 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    32% identity, 96% coverage of query (83.2 bits)

DvMF_1963 ATP phosphoribosyltransferase (EC 2.4.2.17) from Desulfovibrio vulgaris Miyazaki F
    31% identity, 93% coverage of query (81.6 bits)

Build an alignment

Build an alignment for WP_078429924.1 and 35 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

DVU0114 ATP phosphoribosyltransferase (EC 2.4.2.17) from Desulfovibrio vulgaris Hildenborough JW710
    29% identity, 93% coverage of query (80.5 bits)

4yb6A / Q5HSJ4 Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with the inhibitors amp and histidine (see paper)
    30% identity, 97% coverage of query (74.7 bits)

5ubgA Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni with bound phosphoribosyl-atp
    30% identity, 97% coverage of query (74.7 bits)

4yb7A Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with atp
    30% identity, 97% coverage of query (74.7 bits)

Q5HSJ4 ATP phosphoribosyltransferase (EC 2.4.2.17) from Campylobacter jejuni (see 3 papers)
Q9PM78 ATP phosphoribosyltransferase (EC 2.4.2.17) from Campylobacter jejuni (see paper)
    30% identity, 97% coverage of query (74.3 bits)

4yb7C Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with atp
    30% identity, 97% coverage of query (74.3 bits)

5ubiA Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni with bound prpp
    30% identity, 96% coverage of query (73.9 bits)

5ub9A Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni
    30% identity, 97% coverage of query (72.8 bits)

4yb6E Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with the inhibitors amp and histidine
    30% identity, 97% coverage of query (71.6 bits)

Q56US5 ATP phosphoribosyltransferase (EC 2.4.2.17) from Alyssum montanum (see paper)
    30% identity, 79% coverage of query (69.7 bits)

Q56UT3 ATP phosphoribosyltransferase (EC 2.4.2.17) from Odontarrhena lesbiaca (see paper)
    26% identity, 95% coverage of query (68.9 bits)

AtATP-PRT1 / Q9S762 ATP-phosphoribosyl transferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
HIS1A_ARATH / Q9S762 ATP phosphoribosyltransferase 1, chloroplastic; ATP-PRTase 1; AtATP-PRT1; EC 2.4.2.17 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9S762 ATP phosphoribosyltransferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
    27% identity, 95% coverage of query (66.2 bits)

Q56UT2 ATP phosphoribosyltransferase (EC 2.4.2.17) from Odontarrhena lesbiaca (see paper)
    25% identity, 95% coverage of query (64.3 bits)

his1 / RF|NP_594525.1 ATP phosphoribosyltransferase; EC 2.4.2.17 from Schizosaccharomyces pombe (see paper)
his1 / AAA92790.1 ATP phosphoribosyltransferase from Schizosaccharomyces pombe (see paper)
    24% identity, 86% coverage of query (63.9 bits)

6czmE / G7JFL4 Crystal structure of medicago truncatula atp-phosphoribosyltransferase in tense form (see paper)
    28% identity, 77% coverage of query (63.2 bits)

G7JFL4 ATP phosphoribosyltransferase (EC 2.4.2.17) from Medicago truncatula (see paper)
    28% identity, 77% coverage of query (62.8 bits)

AtATP-PRT2 / Q8GSJ1 ATP-phosphoribosyl transferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
HIS1B_ARATH / Q8GSJ1 ATP phosphoribosyltransferase 2, chloroplastic; ATP-PRTase 2; AtATP-PRT2; EC 2.4.2.17 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    24% identity, 99% coverage of query (60.5 bits)

6czmF / G7JFL4 Crystal structure of medicago truncatula atp-phosphoribosyltransferase in tense form (see paper)
    24% identity, 91% coverage of query (44.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory