Searching for up to 100 curated homologs for WP_078717452.1 NCBI__GCF_900167125.1:WP_078717452.1 (265 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

aroA' / Q57843 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase monomer (EC 4.1.2.13; EC 2.2.1.10) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 3 papers)
ADHS_METJA / Q57843 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; ADH synthase; ADHS; ADTH synthase; Transaldolase-like ADHS; EC 2.2.1.10 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 3 papers)
Q57843 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase (EC 2.2.1.10) from Methanocaldococcus jannaschii (see 3 papers)
    56% identity, 98% coverage of query (312 bits)

2qjgA / Q57843 M. Jannaschii adh synthase complexed with f1,6p (see paper)
    56% identity, 98% coverage of query (312 bits)

ADHS_METMP / Q6LZE3 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; ADH synthase; ADHS; ADTH synthase; EC 2.2.1.10 from Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL) (see paper)
    53% identity, 99% coverage of query (307 bits)

griI / A0JC77 2-amino-4,5-dihydroxy-6-one-heptanoic acid-7-phosphate synthase subunit (EC 4.1.2.56) from Streptomyces griseus (see paper)
GRII_STRGR / A0JC77 2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate synthase; EC 4.1.2.56 from Streptomyces griseus (see paper)
A0JC77 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase (EC 4.1.2.56) from Streptomyces griseus (see paper)
    42% identity, 95% coverage of query (191 bits)

ptmB1 / D8L2V7 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase (EC 4.1.2.56) from Streptomyces platensis (see 4 papers)
    44% identity, 89% coverage of query (191 bits)

creI / A0A0K2JKT6 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase (EC 4.1.2.56) from Streptomyces cremeus (see paper)
    45% identity, 91% coverage of query (189 bits)

ALF1_THEKO / Q8J308 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; Tk-fba; EC 4.1.2.13 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    33% identity, 92% coverage of query (150 bits)

fba / P58314 fructose-1,6-bisphosphate aldolase subunit (EC 4.1.2.13) from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see paper)
    32% identity, 92% coverage of query (144 bits)

P58314 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; EC 4.1.2.13 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
    32% identity, 92% coverage of query (144 bits)

ALF1_THETK / P58315 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; FBPA; EC 4.1.2.13 from Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1) (see 3 papers)
    32% identity, 95% coverage of query (131 bits)

ALF1_HALS3 / B0R3Y0 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; EC 4.1.2.13 from Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) (see paper)
    32% identity, 91% coverage of query (129 bits)

2yceE / P58315 Structure of an archaeal fructose-1,6-bisphosphate aldolase with the catalytic lys covalently bound to the carbinolamine intermediate of the substrate. (see paper)
    32% identity, 92% coverage of query (128 bits)

1w8sA The mechanism of the schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates
    33% identity, 92% coverage of query (128 bits)

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Build an alignment for WP_078717452.1 and 13 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

LSRF_SALTY / Q8ZKQ0 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase; EC 2.3.1.245 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    28% identity, 99% coverage of query (117 bits)

LsrF / b1517 3-hydroxy-2,4-pentadione 5-phosphate thiolase (EC 2.3.1.245) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
lsrF / P76143 3-hydroxy-2,4-pentadione 5-phosphate thiolase (EC 2.3.1.245) from Escherichia coli (strain K12) (see 6 papers)
LSRF_ECOLI / P76143 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase; EC 2.3.1.245 from Escherichia coli (strain K12) (see 4 papers)
P76143 3-hydroxy-5-phosphooxypentane-2,4-dione thiolase (EC 2.3.1.245) from Escherichia coli (see 2 papers)
    28% identity, 99% coverage of query (113 bits)

4p2vA / P76143 Structure of the ai-2 processing enzyme lsrf in complex with the product of the lsrg reaction p-hpd (see paper)
    28% identity, 99% coverage of query (110 bits)

3gndA Crystal structure of e. Coli lsrf in complex with ribulose-5-phosphate
    28% identity, 99% coverage of query (110 bits)

3glcA Crystal structure of e. Coli lsrf in complex with ribose-5-phosphate
    28% identity, 99% coverage of query (110 bits)

DhnA / b2097 fructose-bisphosphate aldolase class I (EC 4.1.2.13) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
fbaB / P0A991 fructose-bisphosphate aldolase class I (EC 4.1.2.13) from Escherichia coli (strain K12) (see 12 papers)
ALF1_ECOLI / P0A991 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; EC 4.1.2.13 from Escherichia coli (strain K12) (see paper)
    22% identity, 86% coverage of query (50.1 bits)

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